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| Number | Title | Issue Date |
| 7413735 | Pharmaceutical composition comprising arginine deiminase for inhibiting angiogenesis The present invention relates to a pharmaceutical composition for inhibiting angiogenesis which comprises arginine deiminase as an active ingredient, where the arginine deiminase, obtained from Mycoplasma arginini or prepared by a genetic recombination techni... | 08/19/2008 |
| 7407783 | Fructosylamine oxidase The present invention provides a fructosylamine oxidase which is obtainable by culturing Fusarium proliferatum, and purifying two types of fructosylamine oxidase (FAO) with different substrate specificities from the culture, and which is useful in the measure... | 08/05/2008 |
| 7407784 | L-amino acid oxidase with cytotoxic activity from The present invention relates to a cytotoxic polypeptide which is an L-amino acid oxidase isolated from the ink of the sea hare Aplysia punctata. ... | 08/05/2008 |
| 7371928 | Plant seed-specific expression promoter derived from sesame and seed-specific expression vector comprising the promoter Provided are a seed-specific expression promoter derived from sesame microsomal oleic acid desaturase (Si-FAD2) gene, an intron for expression enhancement, a seed-specific expression vector including the promoter and/or the intron, and a transgenic plant transformed... | 05/13/2008 |
| 7368284 | Porcine CMP-N-Acetylneuraminic acid hydroxylase gene The present invention provides porcine CMP-N-Acetylneuraminic-Acid Hydroxylase (CMP-Neu5Ac hydroxylase) protein, cDNA, and genomic DNA regulatory sequences. Furthermore, the present invention includes porcine animals, tissues, and organs, as well as cells and cell l... | 05/06/2008 |
| 7332311 | Fatty acyl-CoA: fatty alcohol acyltransferases By this invention, nucleic acid sequences encoding for fatty acyl-CoA:fatty alcohol acyltransferase (wax synthase) are provided, wherein said wax synthase is active in the formation of a wax ester from fatty alcohol and fatty acyl-CoA substrates. Of special interest... | 02/19/2008 |
| 7329520 | Fructosyl peptide oxidase and utilization thereof The present invention is directed to a defructosylation enzyme originating from a plant, a method of defructosylating a fructosylated peptide or protein through use of the enzyme, and a method of measuring a fructosylated peptide or protein. ... | 02/12/2008 |
| 7323328 | Obligately symbiotic thermophile SC-1 producing thermostable L-tyrosine phenol-lyase and L-tryptophan indole-lyase The present invention relates to a novel obligately symbiotic thermophile Symbiobacterium toebii SC-1 (Accession NO: KCTC 0685BP), and a thermostable L-tyrosine phenol-lyase and L-tryptophan indole-lyase produced by Symbiobacterium toebii SC-1. The pre... | 01/29/2008 |
| 7323167 | Method of treatment with modified arginine deiminase The present invention is directed to arginine deiminase modified with polyethylene glycol, to methods of treating cancer, and to methods of treating and/or inhibiting metastasis. ... | 01/29/2008 |
| 7319027 | Thermostable Omega-Transaminases Thermostable omega-transaminases, particularly thermostable omega-transaminases which have a high reaction rate and which are tolerant to high concentrations of donor amine, can be used to enrich enantiomerically a mixture of chiral amines or to synthesize stereosel... | 01/15/2008 |
| 7285406 | Nucleic acid fragments encoding nitrile hydratase and amidase enzymes from 5-MGAM-4D and recombinant organisms expressing those enzymes useful for the production of amides and acids The invention relates to the isolation, sequencing, and recombinant expression of genes encoding either a nitrile hydratase (NHase) or amidase (Am) from Comamonas testosteroni 5-MGAM-4D, where the NHase is useful for catalyzing the hydration of nitrites to th... | 10/23/2007 |
| 7279329 | Expression system for producing collagen A DNA molecule consisting of the nucleotide sequence of SEQ ID NO: 1, which encodes a collagenous (COL1) domain and a C-terminal noncollagenous (NC1) domain of type XXI collagen. Expression systems and methods for the expression of the DNA molecule are also provided... | 10/09/2007 |
| 7276360 | Thermostable omega-transaminases Thermostable omega-transaminases, particularly thermostable omega-transaminases which have a high reaction rate and which are tolerant to high concentrations of donor amine, can be used to enrich enantiomerically a mixture of chiral amines or to synthesize stereosel... | 10/02/2007 |
| 7273703 | Detection of mutations The present invention relates to a polypeptide which is a flavin-containing monooxygenase 3 (FMO3), wherein said FMO3 is a polypeptide comprising at least a sequence having at least 85% identity with the polypeptide sequence SEQ ID NO: 15, in particular to a polypep... | 09/25/2007 |
| 7268215 | Photoprotein derived from okinawan squid and gene encoding the photoprotein By using a bioluminescence, a method for detection of a monovalent cation is provided and the method is a high sensitive and simple method. According to the present invention, an amino acid sequence of symplectin and a base sequence encoding the protein are provided... | 09/11/2007 |
| 7267969 | Thermostable omega-transaminases Thermostable omega-transaminases, particularly thermostable omega-transaminases which have a high reaction rate and which are tolerant to high concentrations of donor amine, can be used to enrich enantiomerically a mixture of chiral amines or to synthesize stereosel... | 09/11/2007 |
| 7264952 | Thermostable omega-transaminases Thermostable omega-transaminases, particularly thermostable omega-transaminases which have a high reaction rate and which are tolerant to high concentrations of donor amine, can be used to enrich enantiomerically a mixture of chiral amines or to synthesize stereosel... | 09/04/2007 |
| 7262038 | Simplified eukaryotic nitrate reductase The invention provides modification to the polynucleotide coding sequence for Pichia angusta NAD (P)H: nitrate reductase [YNaR1; GenBank accession number Z49110], which has Enzyme Commission number 1.7.1.2 (formerly EC 1.6.6.2), yielding the polynucleotide co... | 08/28/2007 |
| 7256016 | Recycling system for manipulation of intracellular NADH availability The present invention describes a novel recombinant NADH recycling system that is used as a process for producing reduced compounds. In a specific embodiment, the reduced compounds include ethanol, succinate, lactate, a vitamin, a pharmaceutical and a biodegraded or... | 08/14/2007 |
| 7250269 | Composition for assaying glycoprotein Compositions for accurately assaying a glycated protein by: 1) avoiding effects of globulin and ascorbic acid components, 2) siabilizing proteases and at least enzymes acting on glycated amino acids; 3) accurately assaying albumin; and 4) assaying glycated albumin w... | 07/31/2007 |
| 7247460 | Thermostable omega-transaminases Thermostable omega-transaminases, particularly thermostable omega-transaminases which have a high reaction rate and which are tolerant to high concentrations of donor amine, can be used to enrich enantiomerically a mixture of chiral amines or to synthesize stereosel... | 07/24/2007 |
| 7241602 | Nucleic acid sequences encoding enantioselective amidases The invention relates to nucleic acid sequence encoding enantioselective amides with an amino acid sequence of SEQ ID NO: 2. The invention also relates to a process for fermentation, comprising a batch and a feed phase, of a microorganism in a fermentation medium, w... | 07/10/2007 |
| 7235378 | Method of selectively determining glycated hemoglobin A method of determining glycated hemoglobin is provided, by which a ratio of the glycated hemoglobin in a sample can be determined accurately and easily. The ratio of glycated hemoglobin can be determined by degrading a glycated hemoglobin in a whole blood sample se... | 06/26/2007 |
| 7229812 | Modified sarcosine oxidase, process for producing the same and reagent composition using the same A protein having been modified by addition, deletion, insertion or substitution of at least one amino acid in an amino acid sequence constituting a protein having a sarcosine oxidase activity and still having the sarcosine oxidase activity, characterized by having a... | 06/12/2007 |
| 7217415 | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase for therapeutic use According to the present invention, a series of genes are identified in Group B Streptococcus, the products of which may be located on the outer surface of the organism. The genes, or functional fragments thereof, may be useful in the preparation of therapeut... | 05/15/2007 |
| 7217544 | Method for the preparation of L-amino acids from D-amino acids The invention relates to recombinant microorganisms which, in comparison to the starting organism, have a higher concentration or activity of a D-amino acid oxidase, of an L-amino acid dehydrogenase, of an NADH cosubstrate regenerating enzyme and, if necessary, of a... | 05/15/2007 |
| 7214526 | Alleles of the mqo gene from coryneform bacteria The invention relates to mutants and alleles of the coryneform bacterium mqo gene which encodes malate quinone oxidoreductases which contain any amino acid apart from L-serine at position 111, or a comparable position, in the amino acid sequence, and to processes fo... | 05/08/2007 |
| 7208302 | Deracemisation of amines The present invention relates to a method for the deracemisation or chiral inversion of chiral amines by enzymatic treatment. The method employs a stereoselective enzymatic conversion and either a non-selective or partially selective chemical or enzymatic conversion... | 04/24/2007 |
| 7208303 | Bacterial nitric oxide synthases and uses thereof The present invention relates to isolated nucleic acid molecules encoding nitric oxide synthases. The isolated nucleic acid molecules and their encoded protein or polypeptides are useful in methods for attaching a nitrogen group to a target moiety of a compound and ... | 04/24/2007 |
| 7202070 | Method for reductive amination of a ketone using a mutated enzyme Methods for chemically transforming compounds using a mutated enzyme are provided, and more particularly a method for the production of an amino acid from a target 2-ketoacid, the production of an amine from a target ketone and the production of an alcohol from a ta... | 04/10/2007 |
| 7198785 | Systems and methods related to degradation of uremic toxins The present invention generally relates to the treatment of uremic toxins in vivo using uremic toxin-treating enzymes, and/or cells capable of producing uremic toxin-treating enzymes or otherwise reacting with uremic toxins. Non-limiting examples of cases where the ... | 04/03/2007 |
| 7192729 | Methods for assaying homocysteine The present invention relates to compositions and methods for assaying homocysteine (Hcy) and thus related moieties, e.g., S-adenosylhomocysteine (SAH) or adenosine. More particularly, assay methods that employ, mutant SAH hydrolase having binding affinity for Hcy, ... | 03/20/2007 |
| 7186699 | Method for treating cancer by vector-mediated delivery of one or more anti-angiogenic or pro-apoptotic genes The present invention provides therapeutic compositions and methods for vector-mediated delivery and in vivo expression of polynucleotides encoding anti-cancer compounds that are effective in the treatment of cancer. In particular, the invention relates to the use o... | 03/06/2007 |
| 7179615 | Method of prophylaxis and treatment The present invention relates generally to a method for the prophylaxis and treatment of parasitic infections in animals and birds. More particularly, the present invention contemplates a method for the prophylaxis and treatment of Plasmodium infection in mam... | 02/20/2007 |
| 7172885 | Thermostable omega-transaminases Thermostable omega-transaminases, particularly thermostable omega-transaminases which have a high reaction rate and which are tolerant to high concentrations of donor amine, can be used to enrich enantiomerically a mixture of chiral amines or to synthesize stereosel... | 02/06/2007 |
| 7169685 | Wafer back side coating to balance stress from passivation layer on front of wafer and be used as die attach adhesive A method for balancing layer-caused compressive or tensile stress in a semiconductor die, die wafer or similar substrate uses a stress-balancing layer (SBL) attached to the opposite side from the stress-causing layer before the die or wafer is significantly warped a... | 01/30/2007 |
| 7166465 | Constitutive promoter from The present invention is directed to a promoter derivable from an Arabidopsis ENDO gene. Nucleic acid constructs, vectors, plant cells and transgenic plants comprising the promoter are also provided. ... | 01/23/2007 |
| 7160690 | Nitrate sensor A biosensor method and apparatus for detecting and measuring nitrate. The biosensor is based on the fluorescence properties of a receptor molecule fragment. The biosensor apparatus contains the active-site fragment of the receptor molecule for detecting nitrate. Bot... | 01/09/2007 |
| 7157255 | Process for the preparation of dihydroxy esters and derivatives thereof A process is provided for the preparation of a compound of formula (1) wherein R and R′ represent optionally substituted hydrocarbyl groups and X represents a hydrocarbyl linking group. The process comprises ei... | 01/02/2007 |
| 7153666 | Methods and compositions for determination of glycated proteins This invention relates generally to the field of glycated protein detection. In particular, the invention provides chimeric proteins, nucleic acids encoding the chimeric proteins, methods and kits for assaying for a glycated protein in a sample, using inter alia, an... | 12/26/2006 |
