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| Number | Title | Issue Date |
| 8067214 | Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors The invention provides a non-naturally occurring microbial organism having 4-hydroxybutanoic acid (4-HB) and 1,4-butanediol (1,4-BDO) biosynthetic pathways. The pathways include exogenous nucleic acids encoding a) an α-ketoglutarate decarboxylase; b) a 4-hydroxybut... | 11/29/2011 |
| 7968319 | Method for producing 1,3-propanediol and 2,3-butanediol from raw starch material The invention discloses a method for producing 1,3-propanediol and 2,3-butanediol from raw starch materials, including the following steps: 1) Candida krusei or Hansenula Arabitolgens Fang are inoculated into a fermentation medium with the saccharifyin... | 06/28/2011 |
| 7923226 | Synthesis of 1,2,4-butanetriol enantiomers from carbohydrates A bioengineered synthesis scheme for the production of L-1,2,4-butanetriol, D-1,2,4-butanetriol and racemic mixtures thereof from a carbon source is provided. Methods of producing L-1,2,4-butanetriol, D-1,2,4-butanetriol and racemic mixtures thereof are also provide... | 04/12/2011 |
| 7867740 | mannitol dehydrogenase Nucleic acids encoding Thermotoga maritima mannitol dehydrogenase and the Thermotoga maritima mannitol dehydrogenase polypeptide are disclosed. Further provided are an electrochemical bioreactor system and a bioreactor electrode that can be used to con... | 01/11/2011 |
| 7858350 | Microorganisms for the production of 1,4-butanediol The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO) pathway comprising at least one exogenous nucleic acid encoding a BDO pathway enzyme expressed in a sufficient amount to produce BDO. The invention additionally prov... | 12/28/2010 |
| 7846702 | Method for preparing xylitol with high yield using recycling microorganism Provided is a process for continuously producing xylitol in high yield and productivity using a vacuum microfiltration bioreactor containing a fermentation medium for a strain of the genus Candida, which includes: 5 300 g/l of xylose, 1 10 g/l of urea, 1 10 g... | 12/07/2010 |
| 7807426 | Processes for producing optically active 1-substituted 2-methylpyrrolidine The present invention relates to a process for producing an optically active 1,4-pentanediol by asymmetrically reducing 5-hydroxy-2-pentanone, which is easily available at low cost. The present invention also relates to a process for producing an optically active 1-... | 10/05/2010 |
| 7745184 | Process for the biological production of 1,3-propanediol with high yield The present invention provides a microorganism useful for biologically producing 1,3-propanediol from a fermentable carbon source at higher yield than was previously known. The complexity of the cofactor requirements necessitates the use of a whole cell catalyst for... | 06/29/2010 |
| 7625728 | Process for the simultaneous production of xylitol and ethanol Effective processes are provided for the production of xylitol and ethanol and other products from solutions derived from lignocellulose-containing material in biomass. The solutions can be hydrolyzed or partially hydrolyzed before being fermented with microbes. The... | 12/01/2009 |
| 7582457 | Method for the production of 1,3-propanediol by recombinant organisms comprising genes for coenzyme B12 synthesis Recombinant organisms are provided comprising genes encoding cob(II)alamin reductase, cob(I)alamin adenosyltransferase, glycerol dehydratase and 1,3-propanediol oxidoreductase activities useful for the production of 1,3-propanediol from a variety of carbon substrate... | 09/01/2009 |
| 7427500 | Method for preparing xylitol with high yield using recycling microorganism Provided is a process for continuously producing xylitol in high yield and productivity using a vacuum microfiltration bioreactor containing a fermentation medium for a strain of the genus Candida, which includes: 5 300 g/l of xylose, 1 10 g/l of urea, 1 10 g... | 09/23/2008 |
| 7405063 | Biooxidation capabilities of sp A bioprocess for producing carboxylic acids, alcohols and aldehydes is provided by culturing Candida sp. in a fermentation medium containing various defined substrates. ... | 07/29/2008 |
| 7381553 | Highly active xylose reductase from A new xylose reductase encoding gene from Neurspora crassa was heterologously expressed in E. coli as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was shown to have a high turnover rate and catalytic efficienc... | 06/03/2008 |
| 7371558 | Process for the biological production of 1,3-propanediol with high yield The present invention provides a microorganism useful for biologically producing 1,3-propanediol from a fermentable carbon source at higher yield than was previously known. The complexity of the cofactor requirements necessitates the use of a whole cell catalyst for... | 05/13/2008 |
| 7358072 | Fermentative production of mannitol The invention provides processes for continuous fed-batch fermentative production and continuous recycle fermentative production of mannitol. ... | 04/15/2008 |
| 7341855 | Plant mangrove-associated fungus and a simple and efficient method of obtaining high yield of pure mannitol from the same The present invention relates to a plant mangrove-associated fungus Curvularia lunata, and a simple and efficient method of obtaining high yield of pure mannitol from a plant mangrove-associated fungus Curvularia lunata, said method comprising steps of... | 03/11/2008 |
| 7323539 | Polytrimethylene ether glycol and polytrimethylene ether ester with excellent quality A process is provided comprising contacting 1,3-propanediol with a suitable polymerization catalyst to produce polytrimethylene ether glycol or random polytrimethylene ether ester, wherein the 1,3-propanediol comprises about 10 microg/g or less peroxide compounds, b... | 01/29/2008 |
| 7267972 | Method for preparing 1,3-propanediol by a recombinant micro-organism in the absence of coenzyme b12 or one of its precursors The invention concerns a method for preparing 1,3-propanediol from a carbon-containing substance, said method comprising a step which consists in culturing a recombinant micro-organism not producing coenzyme B12 in the absence of coenzyme B12 or one of its precursor... | 09/11/2007 |
| 7247468 | Method for producing optically active 1,2-diols by microorganism culturing A method for producing an optically active compound comprising: a first step of culturing a microorganism capable of assimilating either the R-isomer or the S-isomer of a compound represented by Formula (1): | 07/24/2007 |
| 7247458 | Enzymatic decarboxylation of 2-keto-L-gulonic acid to produce xylose The invention is drawn to the enzymatic decarboxylation of 2-keto-L-gulonic acid (2-KLG) to produce xylose. The invention is also drawn to a method to detect xylose in vitro or in vivo (intracellularly), which employs an L-xylose dehydrogenase. ... | 07/24/2007 |
| 7229558 | Chromatographic separation method A method for fractionating a solution into two or more fractions. More particularly the invention relates to a method for fractionating a solution by a chromatographic simulated moving bed (SMB) process in which the dissolved substances present in the feedstock are ... | 06/12/2007 |
| 7229803 | Reaction of (di)amines in the presence of a lysine oxidase and of a reducing agent The invention relates to methods for reacting (di)amines as substrates in the presence of a lysine oxidase arid a reducing agent, resulting in alcohols, diols or cyclic secondary amines. In a particular embodiment, the invention is directed to methods of preparing c... | 06/12/2007 |
| 7226761 | Manufacture of five-carbon sugars and sugar alcohols The invention relates to the methods of manufacturing five-carbon sugars and sugar alcohols as well as other compounds derived from pentose-phosphate pathway from readily available substrates such a hexoses using metabolically engineered microbial hosts. ... | 06/05/2007 |
| 7169588 | Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism A new polypropylene terephthalate composition is provided. The polypropylene terephthalate is comprised of 1,3-propanediol and terephthalate. The 1,3-propanediol is produced by the bioconversion of a fermentatble carbon source, preferable glucose. The resulting poly... | 01/30/2007 |
| 7135309 | Processes for the bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism A process is provided for the bioconversion of a carbon substrate to 1,3-propanediol by a single organism utilizing microorganisms, such as, Citrobacter, Enterobacter, Clostridium, Klebsiella, Aerobacter, Lactobacillus, Aspergillus, Saccharomyces, Zygosaccharomyc... | 11/14/2006 |
| 7109005 | Process for the simultaneous production of xylitol and ethanol Effective processes are provided for the production of xylitol and ethanol and other products from solutions derived from lignocellulose-containing material in biomass. The solutions can be hydrolyzed or partially hydrolyzed before being fermented with microbes. The... | 09/19/2006 |
| 7098368 | Hydrogenation of biochemical derived 1,3 -propanediol The invention discloses a hydrogenation process for removing impurities and controlling acid for use in downstream processing of biochemically-derived 1,3-propanediol. Preferably, the biochemically-derived 1,3-propanediol, before the contacting, has an initial color... | 08/29/2006 |
| 7067300 | Process for the biological production of 1,3-propanediol with high titer The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanedio... | 06/27/2006 |
| 7060477 | Epoxide hydrolases of origin The invention concerns proteins of fungal origin having an epoxide hydrolase activity, such as those obtained in essentially pure form by extraction from fungi cells, or by culturing in host cells transformed by a nucleotide sequence coding for said fungal proteins.... | 06/13/2006 |
| 7056439 | Process for producing 1, 3-propanediol Disclosed herein are processes for the recovery of 1,3-propanediol from an aqueous feed stream. The present invention involves contacting an aqueous feed stream that comprises water, 1,3-propanediol, and at least one contaminant with at least one solvent extractant ... | 06/06/2006 |
| 7049109 | Method of producing 1,2-propanediol using A method of producing 1,2-propandiol is provided. The method includes incubating Klebsiella pneumoniae in a medium containing 10–30 g/L of a sugar carbon source excluding 6-deoxyhexose, in aerobic conditions; and separating 1,2-propandiol from the cultures.... | 05/23/2006 |
| 7022503 | Process for the stereoselective preparation of functionalized vicinal diols The present invention relates to a process for the kinetic resolution of racemic functionalized epoxides in the presence of microorganisms, crude or pure preparations thereof comprising a polypeptide having epoxide hydrolase activity. Preferred microorganisms are ye... | 04/04/2006 |
| 7005291 | Transformed microorganisms and genes useful in the production of glycerol and 1,3-propanediol Recombinant organisms are provided comprising genes encoding a glycerol-3-phosphate dehydrogenase and/or a glycerol-3-phosphatase activity useful for the production of glycerol from a variety of carbon substrates. The organisms further contain disruptions in the end... | 02/28/2006 |
| 6953684 | Method for the recombinant production of 1,3-propanediol The present invention provides a microorganism for the production of 1,3-propanediol from a variety of carbon sources in an organism capable of 1,3-propanediol production and comprising a) at least one gene encoding a dehydratase activity; b) at least one gene encod... | 10/11/2005 |
| 6943001 | Epoxide hydrolases, nucleic acids encoding them and methods for making and using them The invention is directed to polypeptides having epoxide hydrolase activity, polynucleotides encoding the polypeptides, antibodies that bind to these polypeptides, and methods for making and using these polynucleotides and polypeptides. The epoxide hydrolases are us... | 09/13/2005 |
| 6924131 | Xylitol dehydrogenase of acetic acid bacteria and gene thereof Xylitol is produced by allowing xylitol dehydrogenase or cells instoduced with a DNA coding for xylitol dehydrogenase, which is a protein of the following (A) or (B) to act on D-xylulose, and collecting produced xylitol: (A) a prot... | 08/02/2005 |
| 6916639 | Erythritol-producing moniliella strains An isolated strain of the Moniliella species that converts glucose to erythritol with a conversion rate of at least about 45% is disclosed, as is a method of producing erythritol from such a strain. ... | 07/12/2005 |
| 6911565 | Process for the production of xylitol The present invention relates to a process for the production of xylitol. The process utilises ribulose for the preparation of xylitol and involves several different conversion reactions, such as reduction, epimerisation and/or isomerisation. The present invention a... | 06/28/2005 |
| 6900361 | Process for lactose conversion to polyols A process for converting lactose into polyols that includes (a) hydrolyzing lactose to produce a hydrolyzate that includes at least one monosaccharide, (b) subsequently hydrogenating the hydrolyzate to produce an alditol-containing intermediate composition, and (c) ... | 05/31/2005 |
| 6894199 | Process for the production of xylitol The present invention relates to the production of xylitol. In particular, processes utilising L-xylose as an intermediate for xylitol production are described. The present invention also relates to process for the preparation or L-xylose, as an intermediate, by-pro... | 05/17/2005 |
