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| Number | Title | Issue Date |
| 7396667 | Enzymatic depolymerization process of polylactic acid, and producing process of polylactic acid using depolymerization product A depolymerizing process of polylactic acid, wherein the polylactic acid is depolymerized in the presence of a hydrolase in an organic solvent or a supercritical fluid, thereby producing a re-polymerizable oligomer. A producing process of polylactic acid, wherein th... | 07/08/2008 |
| 7125692 | Process for producing monomer A process for producing a monomer for resists represented by the following general formula 1: wherein R1 represents hydrogen or an optionally substituted alkyl group; R2 | 10/24/2006 |
| 7052885 | Process for preparing heterocyclic (R)- and (S)-cyanohydrins A process for preparing enantiomer-enriched heterocyclic (R)- and (S)-cyanohydrins of the formula (I), where R1, R2, R3, R4 independently of one another are H, an unsubstituted or substituted C1–C... | 05/30/2006 |
| 6967239 | Method of filtering viruses from a factor VIII solution Method for preparing a factor VIII solution that is essentially free of viruses and essentially devoid of vWF (von Willebrand factor) and factor VIII-vWF complexes by (a) obtaining a starting factor VIII solution devoid of factor VIII-vWF complexes; and (b) filterin... | 11/22/2005 |
| 6924677 | Phase-locked loop integrated circuits that support clock signal updates during dead zone compensation time intervals PLL integrated circuits include a charge pump having first and second input terminals that are configured to receive UP and DOWN control signals, respectively. A phase detector is also provided. The phase detector is configured to generate the UP and DOWN control si... | 08/02/2005 |
| 6680055 | Mycolactone and related compounds, compositions and methods of use The present invention provides, inter alia, polyketide macrolides including a polyketide macrolide of the structure ##STR1## wherein R1 -R5 are the same or different and each is independently selected from the group consisting of hyd... | 01/20/2004 |
| 6479657 | Crystalline 1-kestose and process for preparing the same A process for producing crystal 1-kestose wherein granular crystal 1-kestose in the form of large crystals can be produced at a high yield is disclosed. A highly pure solution of 1-kestose is concentrated to a Brix of 75 or higher; either seed crystals ar... | 11/12/2002 |
| 6284512 | Chemically modified mutant enzymes and methods for producing them, and screening them for amidase and/or esterase activity The present invention relates to a method for screening chemically modified mutant enzymes for amidase and/or esterase activity. This method includes providing a chemically modified mutant enzyme with one or more amino acid residues from an enzyme being r... | 09/04/2001 |
| 5965604 | Chrolactomycin compound The present invention relates to chrolactomycin compound represented by the following formula (I): ##STR1## or pharmaceutically acceptable salts thereof having antibacterial and antitumor activities.... | 10/12/1999 |
| 5900366 | Production of sophorolipid acetate acids from oils or esters A process for the fed batch production of a sophorolipid composition is described, in which culturing takes place of at least one Candida bombicola strain in a culture medium incorporating a sugar and a nitrogen source and said cultured strain is exposed ... | 05/04/1999 |
| 5817489 | Di-nitrogen heterocycle compositions Compositions comprising novel di-nitrogen heterocycle compounds containing at least one N-meta-substituted alkaryl group are prepared. The compounds of the present invention are useful as antibacterial and as other pharmaceutical agents and as intermediat... | 10/06/1998 |
| 5763233 | Process for the production of δ decalactone This invention provides a process for the production of δ-decalactone by the microbial reduction of massoia lactone, characterized in that a bacterium having the ability to reduce massoia lactone is used as the microorganism. The δ-decalactone produced ... | 06/09/1998 |
| 5753471 | Biotechnological perparation of alcohols, aldehydes and carboxylic acids A process for the biotechnological preparation of alcohols, aldehydes and carboxylic acids by oxidation of compounds of the formula R1 --C(CH3).dbd.CR2 R3, where R1, R2 and R3 ha... | 05/19/1998 |
| 5646022 | Process for the production of gamma nonalactones in natural form Gamma lactones with 9 carbon atoms, saturated or unsaturated and mixtures thereof, in natural form, are obtained by: A) culturing a microorganism selected from the group comprising Pichia ohmeri and Pichia stipitis or both of these in a substrate comprising an... | 07/08/1997 |
| 5641804 | Fungicidal compound comprising a cyclic polylactone The invention is directed to compounds having general formula (I) or general formula (II). Compounds of formulae (I) or (II) have interesting antifungal activities and may, accordingly, be used as active ingredients in fungicidal compositions. ##STR1... | 06/24/1997 |
| 5620874 | Process for producing parasiticidal milbemycin derivatives by culturing streptomyces Compounds of formula (I): ##STR1## wherein R1 is hydrogen or methyl, R2 is hydrogen or (E)-2-methyl 2-butenoyloxy, and R3 is hydrogen or hydroxy, with the proviso that when R3 is hydrogen, R1 and... | 04/15/1997 |
| 5561060 | Penicillium cultures capable of producing 10-membered ring lactones Penicillium cultures capable of producing 10-member ring lactones. It is possible with the aid of Penicillium strains to prepare new 10-membered ring lactones having a pharmacological action.... | 10/01/1996 |
| 5413960 | Antibiotic reuterin The antibiotic ଲ-hydroxypropionaldehyde is obtained by cultivating strains of Lactobacillus reuteri under anaerobic conditions in the presence of glycerol or glyceraldehyde. This antibiotic has activity against Gram positive and Gram negative bacter... | 05/09/1995 |
| 5352586 | Method of determining the presence of an antibiotic produced by Lactobacillus reuteri The antibiotic reuterin is obtained by cultivating strains of Lactobacillus reuteri under controlled conditions. Reuterin has inhibitory activity against Gram positive and Gram negative bacteria, against yeast, Saccharomyces cerevisiae, and against the pr... | 10/04/1994 |
| 5281533 | Scytophycins-producing Scytonema pseudohofmanni microorganisms Scytophycins A, B, C, D and E, an aldehyde and alcohol derivative of scytophycin B and the specified alkanoyl and benzoyl esters of scytophycins A, B, C, D and E and the B derivatives (scytophycin compounds) are novel antineoplastic and antifungal agents.... | 01/25/1994 |
| 5278068 | Biologically pure culture of Cytospora useful as angiotensin II antagonist An organism of the Cytospora species produces substituted hexahydrobenzopyran compounds of the Formulas A, B, or C which are useful as angiotensin II antagonists: ##STR1##... | 01/11/1994 |
| 5266484 | Streptomyces spectabilis strains employed for producing streptovaricin C Disclosed is a method for selecting a mutant strain belonging to the genus Streptomyces which is a hyper-producer of Streptovaricin C superior to those know heretofore. This is accomplished by first subjecting a natural strain of Streptomyces spectabilis ... | 11/30/1993 |
| 5258291 | Process for producing antibiotics A method for separation and recovery of polymeric beads from an antibiotic fermentation broth comprising suspending a mixture of the beads and any inherent mold from the fermentation in an aqueous solution having a specific gravity which is effective to c... | 11/02/1993 |
| 5242815 | Process for preparation of streptovaricin A method for producing streptovaricin by culturing a streptovaricin producing strain in the presence of a nonionic adsorbent. This procedure substantially increases the production efficiency of the streptovaricin. A second embodiment wherein the streptova... | 09/07/1993 |
| 5236832 | Microbiological oxidation of methyl groups in heterocycles A microbiological process for the oxidation of methyl groups in aromatic 5- or 6-member ring heterocycles to the corresponding carboxylic acid. The heterocycle serves as the substrate and exhibits no substituent on the carbon atoms adjacent to the methyl ... | 08/17/1993 |
| 5213973 | Microbiological process for oxidation of methyl groups A microbiological process for oxidation of methyl groups in aromatic 5- or 6-ring heterocycles to the corresponding carboxylic acid. The reaction of the heterocycle takes place by microorganisms of the genus Pseudomonas, which utilize toluene, xylene or c... | 05/25/1993 |
| 5210033 | Process for preparing and selecting hyperproducing microorganism strains used for the process for producing streptovaricin C Disclosed is a method for selecting a mutant strain belonging to the genus Streptomyces which is a hyper-producer of Streptovaricin C superior to those know heretofore. This is accomplished by first subjecting a natural strain of Streptomyces spectabilis ... | 05/11/1993 |
| 5190866 | Process for producing antibiotic streptovaricin A method for separation and recovery of polymeric beads from an antibiotic fermentation broth comprising suspending a mixture of the beads and any inherent mold from the fermentation in an aqueous solution having a specific gravity which is effective to c... | 03/02/1993 |
| 5171676 | Method of introducing hydroxyl groups into artemisinin and its derivatives The fungus Beauveria sulfurescens has been employed to introduce hydroxyl groups into artemisinin and derivatives of artemisinin, an antimalarial. Hydroxylated derivatives of artemisinin and derivatives of artemisinin produced thereby possess antimalarial... | 12/15/1992 |
| 5156961 | Process for producing antibiotics A method for separation and recovery of polymeric beads from an antibiotic fermentation broth comprising suspending a mixture of the beads and any inherent mold from the fermentation in an aqueous solution having a specific gravity which is effective to c... | 10/20/1992 |
| 5126254 | Process for preparation of streptovaricin A method for producing streptovaricin by culturing a streptovaricin producing strain in the presence of a nonionic adsorbent. This procedure substantially increases the production efficiency of the streptovaricin. A second embodiment wherein the streptova... | 06/30/1992 |
| 5112742 | Screening for anti-adhesin antibiotics by employing photoinduced cyanobacteria The present invention relates to the method of screening for antibiotics employing a cyanobacterium, Nostoc muscorum A. The cyanobacterium is photoinduced under specified growing conditions to enable the cyanobacterium to be employed for screening of chem... | 05/12/1992 |
| 5104798 | Microbiological oxidation of methyl groups in heterocycles A microbiological process for the oxidation of methyl groups in aromatic 5- or 6-member ring heterocycles to the corresponding carboxylic acid. The heterocycle serves as the substrate and exhibits no substituent on the carbon atoms adjacent to the methyl ... | 04/14/1992 |
| 5102793 | Stereospecific keto reduction of bicyclooctandione-carboxylic acid esters by microorganisms A microbiological process for sterospecific monoketo reduction of racemic 3-keto-bicyclic carbacyclin intermediates to the corresponding optically active 30 hydroxy compounds is provided.... | 04/07/1992 |
| 5084388 | Method of producing brassinosteroids A method of producing a brassinosteroid is disclosed, wherein crown gall cells capable of producing the brassinosteroid are cultured in a culture medium in the presence of a cultivation aid selected from auxins, sterols, squalene, casamino acid and mixtur... | 01/28/1992 |
| 5045457 | Novel compounds Compounds of formula (II): ##STR1## wherein R3 is optionally protected hydroxy; one of R4 and R5 is optionally protected hydroxy; and the other of R4 and R5 is hydrogen, which are obtainable by t... | 09/03/1991 |
| 5026642 | Process for the enzymatic production of ketones In a process for the reduction of ketones, the keto compounds are enantioselectively reduced to give secondary alcohols by means of microorganisms. Keto compounds of the formula R3 NH--CHR1 --CO--CH2 --COOR2 in which... | 06/25/1991 |
| 5008191 | Macrolide compounds, their preparation and their use Compounds with acaricidal, insecticidal and anthelmintic activities have the formula: ##STR1## wherein: --X--Y-- is selected from the group consisting of --CH2 --CH2 --, --CH2 --CHOH--, --CH.dbd.CH--, and --CH2 | 04/16/1991 |
| 4946782 | Process for preparing compositions containing unsaturated lactones, products produced thereby and organoleptic uses of said products Described is a process for the preparation of compositions of matter containing unsaturated lactones defined according to the generic structure: ##STR1## wherein R represents C6 alkyl or alkenyl; and X represents C2, C... | 08/07/1990 |
| 4885246 | Optically active carbacyclin intermediates and processes for the preparation thereof New intermediate, an optically active (1S,5R)-7,7-alkylenedioxy-2-alkoxycarbonylbicyclo[3.3.0]octan-3-one which is useful for the synthesis of an optically active carbacyclin. This intermediate is prepared, as a non-reduced compound, from a racemic c... | 12/05/1989 |
