Did You Know...
...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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| Number | Title | Issue Date |
| 7455997 | Production of fermentation product A process of producing fermentation product comprising the steps of, (i) forming an acidified suspension of particulate plant derived material comprising a first polysaccharide which is more readily hydrolysable and a second polysaccharide which is more difficult to... | 11/25/2008 |
| 7432085 | Method for producing L-amino acid In a method for producing an L-amino acid by culturing a microorganism having an ability to produce an L-amino acid in a medium to produce and accumulate the L-amino acid in the medium and collecting the L-amino acid from the medium, a Gram-negative bacterium having... | 10/07/2008 |
| 7399616 | Enzymatic synthesis of N-acyl-L-arginine esters The invention relates to a process for preparing a Na-acyl-L-arginine ester, derived from fatty acids and esterified dibasic amino acids, according to the following formula (I), where: X— is Br—, Cl—, or HSO4— R1: is linear alkyl chain from an saturated fatt... | 07/15/2008 |
| 7300776 | L-amino acid-producing bacterium and a method for producing L-amino acid An L-amino acid-producing strain of Escherichia coli is bred by modifying an Escherichia coli K12 strain or a derivative thereof so as to become resistant to L-valine and have an ability to produce one or more L-amino acids selected from the group cons... | 11/27/2007 |
| 7172866 | Methods and gel compositions for encapsulating living cells and organic molecules A method for encapsulating biologics within a hydrogel by using an aqueous solution of an isocyanate-functional hydrogel prepolymer which is mixed with an amount of biologics and an aqueous solution containing a dithiol crosslinking agent under physiological pH cond... | 02/06/2007 |
| 7160703 | Nucleotide sequences coding for the PtsI protein The present invention provides nucleotide sequences from Coryneform bacteria which code for the PtsI protein and a process for the fermentative preparation of amino acids using bacteria in which the ptsI gene is enhanced. ... | 01/09/2007 |
| 7157251 | Process for the racemization of N-protected amino acids using racemase The present invention relates to the processes of racemization and deprotection of special N-protected amino acids in the acylase/racemase system for the total conversion of special N-protected racemic amino acids into optically pure amino acids. ... | 01/02/2007 |
| 7129059 | Process for the preparation of compounds with enhanced optical purity A process for preparation of a compound with enhanced optical purity is disclosed wherein a mixture of the enantiomers of a chiral amine is brought into contact with an enzyme having peptide deformylase activity with a bivalent metal ion as a cofactor. ... | 10/31/2006 |
| 7041468 | Blood glucose tracking apparatus and methods A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand... | 05/09/2006 |
| 7037690 | Method for producing L-amino acid In a method for producing an L-amino acid by culturing a microorganism having an ability to produce an L-amino acid in a medium to produce and accumulate the L-amino acid in the medium and collecting the L-amino acid from the medium, a Gram-negative bacterium having... | 05/02/2006 |
| 7018817 | Process for the preparation of compounds with enhanced optical purity Process for the preparation of a compound with enhanced optical purity wherein a mixture of the enantiomers of a chiral compound of formula 1 wherein: R1 represents an alkyl or an aryl group... | 03/28/2006 |
| 6967097 | Phenylalainine ammonia lyase polypeptide and polynucleotide sequences and methods of obtaining and using same The present provides a Rhodotorula phenylalanine lyase polypeptide, polynucleotides that encode the polypeptide, and methods of obtaining and using these products. In particular the polypeptide can be employed for the production of phenylalanine, phenylalanin... | 11/22/2005 |
| 6953677 | Recombinant L-N-carbamoylase from Arthrobacter aurescens and method of producing L-amino acids therewith A novel rec-L-N-carbamoylase from Arthrobacter aurescens and its method of use for producing L-amino acids. The recombinantly produced L-carbamoylase is unexpectedly stable, so that an industrial method of producing L-amino acids can be established with it, i... | 10/11/2005 |
| 6939706 | Method for decomposing polyesters containing aromatic moieties, a denier reduction method of fiber, and microorganism having activity of decomposing the polyester A polyester containing aromatic moieties is contacted with microorganisms having the activity of decomposing the polyester to decompose or reduce it. Preferably, either or both of Trichosporon FERM BP-6445 or Arthrobacter FERM BP-6444 was contacted wit... | 09/06/2005 |
| 6919190 | Regulation of carbon assimilation The present invention provides a method of increasing the productivity of a microorganism by improving the assimilation of carbon dioxide. Specifically, the invention provides a polypeptide having phosphoenolpyruvate carboxylase activity which does not require acety... | 07/19/2005 |
| 6821760 | Methods for producing L-aspartic acid This invention relates to a method for producing L-aspartic acid comprising treating an ammonium fumarate solution with aspartase to generate an ammonium L-aspartate solution; adding fumaric acid to the solution; and then crystallizing L-aspartic acid from the solut... | 11/23/2004 |
| 6808914 | Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the accDA gene is amplified. ... | 10/26/2004 |
| 6806070 | Use of bacterial extracts of the pseudomonadaceae family as cosmetic agents Use of an extract of bacterium from the family Pseudomonadaceae in the production of cosmetic compositions in particular for combating ageing of the skin. ... | 10/19/2004 |
| 6730518 | Method for preventing photooxidation or air oxidation in food, pharmaceuticals and plastics Disclosed is a method of reducing photooxidation or air oxidation in susceptible materials such as food, plastics or pharmaceuticals comprising mixing the material with an antioxidation composition comprising at least one amino acid, at least one metal ion, and at l... | 05/04/2004 |
| 6656710 | Process for the production of amino acids using racemase and acylase The present invention relates to the processes of racemization and deprotection of special N-protected amino acids in the acylase/racemase system for the total conversion of special N-protected racemic amino acids into optically pure amino acids.... | 12/02/2003 |
| 6617127 | Synthesis and recovery of aspartame involving enzymatic deformylation step The invention relates to the synthesis of aspartame involving enzymatic deformylation of an N-formyl--L-aspartyl-L-phenylalanine compound by treatment with an enzyme having formylmethionyl peptide deformylase activity and having as a co-factor grou... | 09/09/2003 |
| 6559280 | Controlling protein levels in eucaryotic organisms The invention relates to novel compounds comprising a ubiquitination recognition element and a protein binding element. The invention also relates to the use of said compounds for modulating the level and/or activity of a target protein. The compounds are... | 05/06/2003 |
| 6551803 | Method for purification of amino acid containing solutions by electrodialysis A process is described for purifying an amino acid-containing solution by means of electrodialysis, wherein an amino acid-containing solution is employed which is obtained from the fermentation for producing at least one amino acid.... | 04/22/2003 |
| 6420166 | Process for the preparation of D-asparagine derivatives The present invention provides a process for the preparation of D-asparagine derivatives of formula I ##STR1## wherein R1 is an amino protecting group and R2 is an alkyl, a substituted alkyl or a group of formula A R3 (OCH... | 07/16/2002 |
| 6410265 | Gene encoding a putive efflux protein for solvents/antibiotics in Pseudomonas mendocina This invention relates to the isolation of a novel putative efflux gene from Pseudomonas mendocina. The putative efflux gene is useful for probing an organism's efflux system to gain an understanding of the mechanisms of solvent tolerance. The invention f... | 06/25/2002 |
| 6379934 | Process for the fermentative preparation of L-amino acids using coryneform bacteria The invention provides a process for the fermentative preparation of L-amino acids using coryneform bacteria, in which the subunit carrying the biotin-carboxyl carrier protein domain and the biotin-carboxylase domain of the nucleotide sequence encoding th... | 04/30/2002 |
| 6344348 | Process for the production of aspartic acid condensate The invention provides a process for the production of aspartic acid poly-condensate from a carbohydrate comprising the steps of: fermenting a carbohydrate-containing medium by means of a fumaric acid-producing microorganism, whereby a fumarate-containing... | 02/05/2002 |
| 6300105 | Methods for producing a succinimide polymer, an aspartic acid polymer and L-aspartic acid A succinimide polymer is produced by thermally polymerizing an ammonium salt of aspartic acid in the presence of an acid catalyst such as a boric acid catalyst. Another amino acid may be added for copolymerizing with the ammonium salt of aspartic acid. Am... | 10/09/2001 |
| 6258572 | Process for preparing L-aspartic acid An improved process for preparing L-aspartic acid by enzyme-catalyzed reaction of fumaric acid with ammonia, in which process L-aspartic acid is precipitated out by nitric acid and the resultant mother liquor is subjected to a nanofiltration.... | 07/10/2001 |
| 6238895 | Production of aspartic and malic acids with microbacterium The use of strains of the genus Microbacterium for the production of organic acids or amino acids by the enzymatic conversion of a fumaric acid to the organic acid or amino acid desired, as well as methods for such use and the conversion solution produced... | 05/29/2001 |
| 6214589 | Method for producing L-aspartic acid This invention relates to a method for producing L-aspartic acid, comprising the steps of: immobilizing microbial cells containing aspartase to produce an immobilized aspartase; feeding an ammonium fumarate solution into a reactor filled with the immobili... | 04/10/2001 |
| 6168940 | Protein having ethylenediamine-N,N'-disuccinic acid:ethylenediamine lyase acitivity and gene encoding the same The present specification relates to a DNA comprising a nucleotide sequence coding for a polypeptide having ethylenediamine-N,N'-disuccinic acid:ethylenediamine lyase activity, the polypeptide having the amino acid sequence of SEQ ID NO: 1 which may have ... | 01/02/2001 |
| 6150142 | Process for production of L-aspartic acid A process for producing crystalline L-aspartic acid is disclosed essentially consisting of the steps of preparing a mix solution containing fumaric acid, ammonia and an alkaline metal hydroxide, reacting the mix solution with aspartase to give a reaction ... | 11/21/2000 |
| 6143552 | Process for producing L-amino acids by fermentation The present invention provides a process for producing an L-amino acid which comprises culturing in a nutrient medium a microorganism which is capable of producing the L-amino acid and which can not grow in a synthetic medium containing said L-amino acid ... | 11/07/2000 |
| 6133018 | Enzymatic synthesis of chiral amines using -2-amino propane as amine donor 2-Aminopropane is used as the amine donor in the stereoselective synthesis of a chiral amine from a ketone with a transaminase. In a typical embodiment, (S)-1-methoxy-2-aminopropane is prepared by bringing methoxyacetone into contact with a transaminase i... | 10/17/2000 |
| 6103508 | Method for removing fumarase activity, microorganisms obtainable by the method, and production of optically active aminopolycarboxylic acids using the microorganisms This invention relates to a method for removing fumarase activity from a microorganism or processed product thereof having ethylenediamine-N,N'-disuccinic acid ethylenediamine lyase activity, which includes treating the microorganism or processed product ... | 08/15/2000 |
| 6071728 | Process for the production of crystalline aspartic acid The invention provides a process for the preparation of aspartic acid via a fermentation process for the preparation of ammonia fumarate, wherein the pH of the fermentation broth is controlled by the addition of a calcium base to produce a calcium fumarat... | 06/06/2000 |
| 6063615 | Enzymatic acylation of amino acid esters using a carboxylic acid ester substituted with oxygen on the alpha carbon Disclosed is a process for preparing acylated amino esters and a process for preparing optically active amino esters from racemic amino esters with a carboxylic ester as acylating agent, whose acid component has a halogen, nitrogen, oxygen or sulfur atom ... | 05/16/2000 |
| 6015704 | Mutant aspartase and the preparation thereof Disclosed is a mutant aspartase comprising the amino acid sequence of a wild-type E. coli aspartase wherein the amino acid residue at one of positions 25, 123, 421 and 463 is substituted. Also disclosed is a process for preparing the above mutant aspartas... | 01/18/2000 |
| 6011001 | Method of protein therapy by orally administering crosslinked protein crystals A protein such as an enzyme or antibody is immobilized by crosslinking crystals of the protein with a multifunctional crosslinking agent. The crosslinked protein crystals may be lyophilized for storage. A preferred protein is an enzyme such as thermolysin... | 01/04/2000 |
