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| Number | Title | Issue Date |
| 8182860 | Dental filler The present invention provides dental fillers having the optical and/or mechanical characteristics required to dental materials, a method of producing the same, and a dental composite material prepared with use of the dental filler. More specifically, the present in... | 05/22/2012 |
| 8128984 | Implantable material and a method for the preparation thereof A method for the preparation of a regenerated silk fibroin solution comprises the steps of: treating silk or silk cocoons with an ionic reagent comprising an aqueous solution of monovalent cations and monovalent anions, the cations and anions having ionic radii of a... | 03/06/2012 |
| 7815963 | Enhanced bonding layers on titanium materials The present invention provides a dense-coverage, adherent phosphorous-based coating on the native oxide surface of a material. Disclosed phosphorous-based coatings include phosphate and organo-phosphonate coatings. The present invention also provides further derivat... | 10/19/2010 |
| 7749555 | Modification of chemical forces of bone constructs The present invention relates to a method for enhancing ingrowth of host bone comprising: modifying a bone graft structure to provide an ionic gradient to produce a modified bone graft structure; and implanting the modified bone graft structure. The present inventio... | 07/06/2010 |
| 7740897 | Process for producing rigid reticulated articles A method for forming a ceramic article useful as a bone substitute and having an outer surface defining a shape having a bulk volume and having open, interconnecting openings extending throughout the volume and opening through the surface, includes, providing an org... | 06/22/2010 |
| 7687098 | Chemical mechanical vapor deposition device for production of bone substitute material A method for fabricating a substitute component for bone, including the processes of: provision of a chemical spray including at least three of calcium chloride, hydrogen phosphate, hydrogen carbonate and water to form a combined solution; reaction and precipitation... | 03/30/2010 |
| 7648728 | Method for producing bone filter of calcium phosphate A method for producing a calcium phosphate bone filler by preparing a mixed liquid comprising a calcium solution and a phosphoric acid solution in such a manner that a substrate of calcium phosphate exists in the mixed liquid, thereby precipitating calcium phosphate... | 01/19/2010 |
| 7452566 | Osseoinductive magnesium-titanate implant and method of manufacturing the same A magnesium titanate oxide film implant, and a method for preparing the same. The magnesium titanate oxide film implant is prepared by forming a titanium oxide film (a magnesium titanate oxide film) in which magnesium is incorporated into the surface of titanium or ... | 11/18/2008 |
| 7425345 | Apparatus and method for coating objects using an optical system An apparatus comprises a dispenser, a coherent energy source and an beam steering system. The dispenser defines a path of a droplet. The beam steering system is coupled to the coherent energy source and is configured to define a beam path of the coherent energy sour... | 09/16/2008 |
| 7407684 | Multi-step method of manufacturing a medical device A multi-step method of manufacturing a medical device containing therapeutic agents that results in a lower maximum error in the amount of therapeutic agents actually disposed thereon and that allows for differential drug release kinetics along the length of the med... | 08/05/2008 |
| 7390525 | Processes for producing polymer coatings for release of therapeutic agent A method for furnishing a therapeutic-agent-containing medical device is provided. The method comprises: (a) providing a reactive layer comprising a cross-linking agent on a medical device surface; and (b) subsequently applying a polymer-containing layer, which comp... | 06/24/2008 |
| 7390526 | Methods and materials for nanocrystalline surface coatings and attachment of peptide amphiphile nanofibers thereon Biocompatible composites comprising peptide amphiphiles and surface modified substrates and related methods for attachment thereon. ... | 06/24/2008 |
| 7371424 | Method and apparatus for coating a medical device using a coating head Methods and apparatuses for coating surface of medical devices using coating heads are disclosed. In one embodiment, the invention includes a coating method using a coating head, wherein the coating head comprises at least one outlet orifice from which flows a coati... | 05/13/2008 |
| 7368065 | Implants with textured surface and methods for producing the same Compositions and methods are provided for preparing a metal substrate having a uniform textured surface with a plurality of indentations with a diameter in the nanometer and micrometer range. The textured surface is produced by exposing the substrate to an etching f... | 05/06/2008 |
| 7351433 | Method for producing polymeric sol of calcium phosphate compound and method for coating the same on a metal implant Disclosed is a method for producing a transparent and homogenized polymeric sol of a calcium phosphate compound, containing apatite and having excellent wettability and bioactivity, according to a sol-gel synthesis, and a method for coating the polymeric sol on a me... | 04/01/2008 |
| 7344749 | Method for coating a substrate with calcium phosphate A method for coating substrates with calcium phosphate. The aim of the method is to be able to carry out a simple coating for all materials as well as for particles. To this end, the substrate to be coated is placed in a calcium phosphate gel, whereupon this substra... | 03/18/2008 |
| 7341756 | Coated implants and methods of coating A method including forming a first coating layer derived from an alkoxide on a substrate having a dimension suitable for an implant and forming a second coating layer on the first coating layer that promotes osseointegration. An apparatus comprising a substrate havi... | 03/11/2008 |
| 7323211 | Bone-adherent implant with shock-absorbing property and manufacturing method thereof It is to provide an implant with shock-absorbing property that is able to be strongly secured in a living body as well as a manufacturing method of such implant. The implant comprising: a substrate; a first film on the substrate, which is comprised of a polym... | 01/29/2008 |
| 7323208 | Modified porous materials and method of forming the same Modified porous materials are disclosed having interconnected, complexly shaped three-dimensional surfaces. The modification is accomplished by crosslinking the three-dimensional surfaces and/or by coating the three-dimensional surfaces with a layer of a predetermin... | 01/29/2008 |
| 7292336 | Method and instrument for detecting biomolecular interactions Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An instrument system for detecting a biochemical interaction on a biosensor. The system includes an array of... | 11/06/2007 |
| 7261914 | Method and apparatus for forming a nitride layer on a biomedical device This invention is a method of forming a nitride layer on at least one metal or metal alloy biomedical device, comprising: providing a vacuum chamber with at least one biomedical device positioned thereon on a worktable within the vacuum chamber; reducing the pressur... | 08/28/2007 |
| 7258810 | In-situ oxidized textured surfaces for prosthetic devices and method of making same A textured surface and oxidation layer coating on a metallic material is accomplished through the chemical and/or electrochemical etching of the surface to modify the surface texture and an in-situ oxidation procedure. The surface is useful for the fabrication of pr... | 08/21/2007 |
| 7252685 | Fusion implant and method of making same The present invention provides an implant for use in fusing adjacent bony structures. The implant comprises at least one structural member combined with at least one flexible planar member to retain the at least one structural member to form the implant. ... | 08/07/2007 |
| 7241313 | Surgical implant A surgical implant comprises a core region and a porous surface region extending over at least part of the core region. The surface region has a predetermined pore volume fraction. A method of manufacturing a surgical implant comprises: (i) loading metallic powder h... | 07/10/2007 |
| 7186364 | Composite prosthetic bearing constructed of polyethylene and an ethylene-acrylate copolymer and method for making the same An implantable prosthetic bearing is constructed of a composite material having a first layer and second layer. The first layer has an articulating surface defined therein, whereas the second layer has a engaging surface defined therein for engaging either another p... | 03/06/2007 |
| 7169185 | Canine acetabular cup A plurality of canine acetabular cups designed to fit within different sized spherical reamed bone cavities to produce controlled interference without use of cements, screws or nails. Each of the canine acetabular cups, regardless of size, mates with a common femora... | 01/30/2007 |
| 7169186 | Monopolar constrained acetabular component The present invention provides monopolar acetabular liners that can enclose a femoral head to form a hip replacement prosthesis, wherein the liner has a rim that creates an orifice, wherein the orifice has a diameter that is smaller than the diameter of the femoral ... | 01/30/2007 |
| 7156851 | Implant and process of modifying an implant surface An implant and a process of modifying an implant surface, which implant is in particular a hip implant, a tooth implant, a bone screw, fixation pin or a fixation nail (pin-fixation), comprising a metallic base body, which implant has a surface modified by a material... | 01/02/2007 |
| 7144428 | Method for surface treatment of implants or prosthesis made of titanium or other materials A section of the implant is treated successively and separately with three different acids—hydrofluoric, sulphuric and hydrochloric acid— to create evenly distributed peaks on the surface and sufficient surface area. Plasma rich in growth factors is then applied... | 12/05/2006 |
| 7087085 | Surface-modified implants An osteogenic implant with improved osteointegration properties, this implant being made of titanium metal or a titanium-based alloy and being suitable for implantation in bones, said implant having a roughened surface, which in the hydroxylated state has been at le... | 08/08/2006 |
| 7077867 | Prosthetic knee joint having at least one diamond articulation surface Prosthetic joints, components for prosthetic joints, superhard bearing and articulation surfaces, diamond bearing and articulation surfaces, substrate surface topographical features, materials for making joints, bearing and articulation surfaces, and methods for man... | 07/18/2006 |
| 7052907 | Adult human dental pulp stem cells in vitro and in vivo The present invention provides a culture of isolated adult human dental pulp stem cells that can differentiate into dentin/pulp tissue that can be used to produce a tooth in a human being. The present invention further provides a method of regenerating human dentin/... | 05/30/2006 |
| 7052514 | Methods and reagents for tissue engineering of cartilage in vitro The present invention makes available an optimal concentration of a hedgehog polypeptide for modulating growth and/or cartilage production by chondrocytes. The present invention allows for improvements in the culturing of chondrocytes to develop cartilaginous tissue... | 05/30/2006 |
| 7041221 | Method for removing oil spills The present invention provides methods and apparatus for removing oil and oil containment for oil spills using crushed glass. ... | 05/09/2006 |
| 7004977 | Soft tissue substitute and method of soft tissue reformation A soft tissue implant material is formed from biologically-compatible polymeric particles. The particles may have a diameter of up to about 500 microns and intraparticulate pores sized for ingrowth of soft tissue. The particles may have an inner core of a first biol... | 02/28/2006 |
| 7001881 | Tribonectins The invention features a tribonectin and a method of tribosupplementation carried out by administering tribonectins directly to an injured or arthritic joint. ... | 02/21/2006 |
| 6994883 | Method for applying a bioactive coating on a medical device The invention relates to the field of medical devices. More in particular, the invention relates to a method for coating by depositing inorganic ions and a bioactive agent to provide sterile medical devices, wherein said coating improves the biocompatibility and/or ... | 02/07/2006 |
| 6994550 | Vapor deposited titanium and titanium-nitride layers for dental devices A coating for a biomedical device is disclosed, including a metal layer and/or a ceramic layer, such as a layer of titanium (Ti) and a layer of titanium-nitride (TiN). The coating can form a coping for a crown for a tooth, the crown including a porcelain layer bonde... | 02/07/2006 |
| 6984236 | Bone connective prosthesis and method of forming same The above-discussed and other problems and deficiencies of the prior art are overcome or alleviated by the improved bone connective prosthesis and method of forming the same of the present invention, comprising the addition of at least one biocompatible metal coupli... | 01/10/2006 |
| 6977095 | Process for producing rigid reticulated articles A process for producing a rigid reticulated article involves coating a reticulated substrate which has open, interconnected porosity with a first dispersion comprising a ceramic or metal powder to form a first coating thereon; drying the coated reticulated substrate... | 12/20/2005 |
