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Class 427/2.19 - Retarded or controlled-release layer produced (e.g., enteric)


Subclass of Class 427 - Coating processes
Definition: Processes in which the product is intended to provide retarded
No. of patents: 47
Last issue date: 03/04/2008


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NumberTitleIssue Date
7338677Methods for manufacturing coated confectionary products
Methods for manufacturing coated confectionary or chewing gum products are provided. The method of manufacturing a confectionary product comprises the steps of providing a confectionary center, heating at least one polyol to the polyol's melting point to produce a m...
03/04/2008
7022663Oral, nasal and pulmonary dosage formulations of copolymer 1
Pharmaceutical compositions useful for treating autoimmune diseases in a mammal comprising as an active ingredient a therapeutically effective amount of Copolymer 1, and microcrystalline cellulose are disclosed. Processes for the manufacture of such compositions are...
04/04/2006
6723372Method for producing encased spherical granular grains
A process for the production of encased, spherical granular grains comprising spraying grains which consist of a prostane derivative and a cyclodextrin vehicle, forming together a prostane-cyclodextrine-clathrate, with an aqueous polymer dispersion of ethyl cellulos...
04/20/2004
5882715Method of preparing an oral preparation provided on the outer side with an enteric coating, as well as an oral preparation obtained by the method
A method of preparing an oral preparation, especially in the form of hard gelatin capsules, tablets or pellets, for use by the administration of drugs or supplementary nutrients for human beings or animals, said preparation on its outer side being provide...
03/16/1999
5851579Aqueous enteric coating compositions
The present invention sets forth an enteric coating composition comprising a blend of a) an alkali-soluble acrylic latex polymer and b) an aqueous solution of ammonium or alkaline salts of cellulose polymers. The invention also sets forth a method for preparing an ...
12/22/1998
5744164Sustained release microparticulate caffeine formulation
The present invention relates to compositions and methods for increasing the alertness of an individual through the administration of a stimulant such as xanthine or an xanthine derivative and preferably caffeine. A particular composition has one or more ...
04/28/1998
5700484Sustained release microparticulate caffeine formulation
The present invention relates to compositions and methods for increasing the alertness of an individual through the administration of a stimulant such as xanthine or an xanthine derivative and preferably caffeine. A particular composition has one or more ...
12/23/1997
5650192Method for manufacturing buccal delivery device
The invention relates to a muco-adherent, soluble device for administering active ingredients, a method of using said device, and an improved method of manufacturing said device using a continuous, enclosed mixing device capable of operating under pressur...
07/22/1997
5641513Tablet coating method
A method for coating pharmaceutical tablets is disclosed in which polymeric coating ingredients are combined with saccharides in a melt spinning operation to form composite particulates. The particulates are then dispersed in water to form an aqueous poly...
06/24/1997
5547683Method for producing microgranulated particle
The present invention relates to a method for producing a microgranulated particle having particle size of not more than 0.2 mm, wherein a fine powder with the average particle size of not more than 10 .mu.m, which is being agitated, tumbled or fluidized,...
08/20/1996
5505983Spherical seed cores, spherical granules and process for production thereof
Pharmacologically inactive spherical seed cores comprising at least 50% by weight of microcrystalline cellulose having an average degree of polymerization of 60 to 375, wherein the spherical seed cores have an average particle size of 100 to 1000 μm, a t...
04/09/1996
5393533Pharmaceuticals microencapsulated by vapor deposited polymers and method
A microencapsulated pharmaceutical is formed by vapor depositing a polymeric film about an active pharmaceutical agent. The film thickness of the vapor deposited film is controlled to provide effective controlled release of said pharmaceutical agent subse...
02/28/1995
5310572Process for forming a coated active agent-containing article
Aqueous coating compositions for forming elastomeric films around active cores (e.g., drugs) comprising a dispersion of pre-crosslinked polyorganosiloxane latex particles, colloidal silica particles, and a water-dispersible organic material (e.g., polyeth...
05/10/1994
5256440Process for producing a tablet core aperture
Process for preparing and film coating a dosage form. An intagliated dosage form core is produced by inscribing one or more areas on the surface of the dosage form core prior to coating. An aqueous dispersion of a polymeric coating is then applied to the ...
10/26/1993
5198227Dual subcoated simulated capsule medicament
A simulated capsule-like medicament comprising a dual subcoating comprising an initial subcoating of a water soluble film forming polymer, e.g. povidone and a secondary subcoating of a mixture of two soluble film forming polymers, e.g. povidone and hydrox...
03/30/1993
5194464Enteric film and preparatoin thereof
An enteric film is produced by spraying on a material a mixed solution of (a) hydroxypropylmethylcellulose phthalate exhibiting a viscosity of about 136 to 204 centistokes as 10% methanol/dichloromethane (1:1 by weight) solution at 20° C., (b) polyethyle...
03/16/1993
5178874Intermittent release dosage form
Veterinary delayed release dosage forms which remain in the rumeno-reticular sac of an animal over an extended period of time and in which the therapeutically active substance has a predictable and delayed release pattern. The compositions comprise a dens...
01/12/1993
5112621Sustained release pharmaceutical composition of diltiazem
A sustained-release pharmaceutical composition which comprises microparticles comprising an active principle, said microparticles being coated with a coating mixture comprising ethyl cellulose and an acrylic resin which is a polymerizate of acrylic and me...
05/12/1992
5098715Flavored film-coated tablet
The invention comprises a flavored thin film coating on solid oral dosage pharmaceutical tablets containing unpleasant tasting ingredients such as triprolidine hydrochloride and pseudoephedrine hydrochloride. The flavored coating of the invention is compr...
03/24/1992
5047258Aqueous spray-coating process
A process for spray-coating tablets and the like utilizing only an acrylate enteric polymer and plasticizer in water is disclosed. The process can be practiced on a commercial scale and requires no antiadherent in the coating formulation. The process comp...
09/10/1991
5026709Method for the preparation of a theophylline sustained release pharmaceutical composition and the composition prepared thereby
A method for the preparation of a sustained release pharmaceutical composition comprising forming a fluidized ring of said particles and contacting said particles maintained suspended in said ring with a liquid composition containing a pharmaceutically ac...
06/25/1991
5023108Aqueous dispersions of waxes and lipids for pharmaceutical coating
This invention relates to the coating of pharmaceutically useful solids with an emulsion comprising a wax/lipid, an emulsifying agent and water, which emulsion can be spray dried to form a powder which can subsequently be dispersed in water and coated ont...
06/11/1991
4948622Method for the preparation of coated solid medicament form
Solid medicament forms, such as granules, beads, tablets, are first coated with a hot aqueous dispersion of a cellulose ether, which is soluble in cold water but insoluble in hot water, and then subjected to a wax treatment with heating to form a masking ...
08/14/1990
4933186Dihydropyridine depot formulation
A pharmaceutical formulation tablet with a long-lasting action for 1 to 2 daily doses having a diameter between about 0.5 and 15 mm and comprising (a) a rapid-release core of a dihydropyridine, (b) a coat containing no active compound and formed of a free-flowing ...
06/12/1990
4853249Method of preparing sustained-release pharmaceutical/preparation
A method of preparing a sustained-release pharmaceutical preparation, which comprises applying a solution of a binder in water or an alcohol and a fine powder of a hydrophobic solid material which does not easily dissolve within the stomach and intestines...
08/01/1989
4816264Sustained release formulations
Drug delivery systems which exhibit sustained release properties when administered are produced using a "dual control" system which employs polymeric agents in core and membrane portions....
03/28/1989
4816259Process for coating gelatin capsules
This invention provides a new gelatin capsule formulation and subcoating for producing soft gelatine capsules having better mechanical strength and an improved capacity for adhering to known coating compositions, particularly enteric coating compositions....
03/28/1989
4800056Process for making dispenser with cooperating elements
A method of forming a dispenser for delivering a beneficial agent to a biological environment. A beneficial agent and an expandable composition are placed in a capsule made of fluid dissolvable material. The capsule is closed and surrounded by a semiperme...
01/24/1989
4775536Enteric coated tablet and process for making
An enteric coated tablet and process is described in which a core tablet of a pharmaceutically active ingredient is provided with an enteric coating layer of a film forming enteric polymer and an overcoat layer of non-enteric film forming polymer; optiona...
10/04/1988
4684516Sustained release tablets and method of making same
This invention relates to new dosage units of medicinal agents for oral administration in the form of tablets which provide a controlled rate of release of the medicament in the gastrointestinal tract. More particularly, the invention relates to dense com...
08/04/1987
4670287Method of film-coating hard capsules
A method of film-coating hard capsules is provided which comprises subjecting, drug-filled hard capsules to a vacuum to remove air entrapped therein and then coating the evacuated capsules while under a vacuum with a film-forming substance which is select...
06/02/1987
4644031Coating for pharmaceutical dosage forms
Coated pharmaceutical dosage forms which are resistant to gastric juice and release their active ingredient rapidly at a predetermined pH value in the range from pH 5 to pH 8 are obtained in accordance with the invention by coating pharmaceutical dosage f...
02/17/1987
4574080Combination formulation
A pharmaceutical oral controlled release multiple-units formulation is prepared by mixing units containing an active substance and coated with a substantially water-insoluble, but water diffusable controlled release coating with particles of an active sub...
03/04/1986
4572833Method for preparing a pharmaceutical controlled release composition
A pharmaceutical oral multiple-units composition with controlled release, in which the individual units are coated units of an active substance, e.g. potassium chloride, which is subject to controlled release in consequence of the units being coated with ...
02/25/1986
4533562Method of preparing coated solid preparations
Solid materials, especially pharmaceutical preparations, are coated, without the use of solvents, with a powdered film-forming polymer and with a liquid plasticizer having an affinity for the polymer....
08/06/1985
4497847Process for coating solid pharmaceutical preparations and coated preparations thus obtained
A plasticizer for film-forming enteric polymers to be used in coating solid pharmaceutical preparations comprises a monoester or diester or both of glycerol with a saturated aliphatic carboxylic acid having from 6 to 10 carbon atoms. This is particularly ...
02/05/1985
4433076Coating agent for medicaments and methods for making and using the same
What are disclosed are methods for making a suspension suitable for use as a coating agent for medicaments by suspending a powder of certain vinyl copolymers in an aqueous solution or suspension of a plasticizer therefor, methods for converting such a sus...
02/21/1984
4367217Dipyricamole sustained release forms comprising lacquer-coated particles and the preparation thereof
This invention relates to a composition for the sustained release of dipyridamole which comprises (i) spheroid particles comprised of dipyridamole or crystallized salts thereof and pharmacologically acceptable acid or acid substance, and (ii) a coating su...
01/04/1983
4226981Ether-ester derivatives of cellulose and their applications
A novel cellulose derivative provided in this invention is a mixed ester of an alkoxy or hydroxyalkoxy substituted cellulose ether, prepared by the esterification reaction of the ether with succinic anhydride and an anhydride of an aliphatic monocarboxyli...
10/07/1980
4218433Constant-rate eluting tablet and method of producing same
A tablet formed with a hollow or hollows in its surface and containing a water-soluble component is coated with a coating agent which is insoluble in water but has water permeability, thereby to obtain a constant-rate eluting medicinal tablet. A process o...
08/19/1980
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