...that Kleenex tissue was originally designed to be a gas mask filter? It was developed at the beginning of World War I to replace cotton, which was then in short supply as a surgical dressing.
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| Number | Title | Issue Date |
| 7785650 | Method for dip coating dosage forms Water soluble, gelatin-free dip coatings for pharmaceutical solid dosage forms such as tablets comprising HPMC and xanthan gum, carrageenan, and mixtures thereof, or HPMC and castor oil or maltodextrin. ... | 08/31/2010 |
| 7335391 | Method for coating implantable devices A method of forming a coating for an implantable medical device, such as a stent, is provided which includes applying a composition to the device in an environment having a selected pressure. ... | 02/26/2008 |
| 7329430 | Method and device for coating pharmaceutical products The present invention relates to a method for coating of a pharmaceutical product. The method comprises the step of producing discrete droplets (7) of controlled size, shape and composition with at least one micro dispenser (1) and distributing droplet... | 02/12/2008 |
| 7300662 | Drug/drug delivery systems for the prevention and treatment of vascular disease A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia f... | 11/27/2007 |
| 7297314 | Fluidized bed device A fluidized bed apparatus has a rotary rotor 4 arranged at the bottom center thereof, a disintegrator mechanism 5 arranged above the rotary rotor 4, and a cylindrical draft tube 6 installed above the disintegrator mechanism 5. A fl... | 11/20/2007 |
| 7267743 | Wax emulsion coating applications Waxes prepared from hydrogenated plant oils, such as castor, palm, and soybean, are used to prepare water based emulsions. The inventive waxes, obtained from naturally derived, renewable resources, were emulsified under anionic, cationic and nonionic conditions, pro... | 09/11/2007 |
| 7229473 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 06/12/2007 |
| 7223286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/29/2007 |
| 7217286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/15/2007 |
| 7201940 | Method and apparatus for thermal spray processing of medical devices The invention relates to devices for the treatment of heart disease and particularly to endo-arterial prostheses, which are commonly called stents. More particularly, the invention relates to methods of manufacturing and coating stents utilizing thermal spray proces... | 04/10/2007 |
| 7163715 | Spray processing of porous medical devices Thermal spray processing and cold spray processing are utilized to manufacture porous starting materials (such as tube stock, wire and substrate sheets) from biocompatible metals, metal alloys, ceramics and polymers that may be further processed into porous medical ... | 01/16/2007 |
| 7087243 | Pharmaceutical coating composition and method of use A composition is disclosed comprising a polymer and a surfactant in a solvent exhibiting a common solubility for the polymer and the surfactant. The composition provides a dosage form for administering a drug over time. ... | 08/08/2006 |
| 6997989 | Medical implant processing chamber Apparatus and method for treating medical implants are provided. The apparatus may include a vessel having a treatment chamber with an inside surface, an outside surface, an entrance, a plurality of fluid passages passing from the outside surface to the inside surfa... | 02/14/2006 |
| 6994895 | Magnetic recording medium including an annealed alloy particle layer and method of producing the same A method of producing a magnetic recording medium including the steps of preparing alloy particles capable of forming a CuAu type or Cu3Au type ferromagnetic order alloy phase, forming an alloy particle layer on a support using the alloy particles, oxidiz... | 02/07/2006 |
| 6946157 | Method and apparatus for monitoring the coating on particle during manufacturing of a pharmaceutical product In a method of monitoring the formation of a coating on a single particle (P), an apparatus is used which comprises means (2,5,6,9) for arranging said particle (P) at a given spatial location, and a fluid supply unit (3) adapted to apply a coating flui... | 09/20/2005 |
| 6939376 | Drug-delivery endovascular stent and method for treating restenosis An intravascular stent and method for inhibiting restenosis, following vascular injury, is disclosed. The stent has an expandable, linked-filament body and a drug-release coating formed on the stent-body filaments, for contacting the vessel injury site when the sten... | 09/06/2005 |
| 6932840 | Implant device A human or animal implant device including a first, inner sealed silicone sheet sac, a second, intermediate sealed silicone sheet sac completely surrounding the first, inner sac, and a third, outer sealed silicone sheet sac completely surrounding the second sac. Eac... | 08/23/2005 |
| 6872336 | Process for producing a pharmaceutical solid preparation containing a poorly soluble drug Among the conventional processes for producing solid dispersion, the solid dispersion obtained by a solvent method is excellent in terms of solubility and bioavailability of a poorly soluble drug. However, due to frequent uses of organic solvents in the solvent meth... | 03/29/2005 |
| 6723372 | Method for producing encased spherical granular grains A process for the production of encased, spherical granular grains comprising spraying grains which consist of a prostane derivative and a cyclodextrin vehicle, forming together a prostane-cyclodextrine-clathrate, with an aqueous polymer dispersion of ethyl cellulos... | 04/20/2004 |
| 6709678 | Easy to swallow oral medicament composition An oral composition which is adapted to be dispersed in an aqueous carrier substantially immediately prior to administration comprises a multiplicity of particles comprising an active substance, the particles being combined with one or more gelling or swelling agent... | 03/23/2004 |
| 6652903 | Dry-copying method for producing flat, individually dosed preparations of active agents A method for metering active ingredient in powder form onto a predetermined area is characterized in that the active ingredient is transferred as electrically charged powder to a roll with the opposite charge, the active ingredient transferred to the r... | 11/25/2003 |
| 6410087 | Deposition of pyrocarbon Pyrolytic carbon of extremely uniform crystalline characteristics and essentially free of discontinuities is obtained in a fluidized bed coater by creating an asymmetric recirculation of the fluidized bed within the high temperature coating chamber. Throu... | 06/25/2002 |
| 6368658 | Coating medical devices using air suspension Methods and apparatuses for coating medical devices and the devices thereby produced are disclosed. In one embodiment, the invention includes a method comprising the steps of suspending the medical device in an air stream and introducing a coating materia... | 04/09/2002 |
| 6296868 | Chewable tablets containing mannitol and aspartame Chewable tablets and particulate food and pharmaceutical products are disclosed which are made from agglomerates comprising an alcohol sugar such as mannitol and a high intensity sweetener such as Aspartame from which agglomerate tablets may be directly c... | 10/02/2001 |
| 6274190 | Method of coating particulate material An apparatus for coating seeds and particulate material includes an elongated tray operably mounted on a support frame with a motor for oscillating the tray to move particulate material from a rearward end to a forward end therealong. The tray includes a ... | 08/14/2001 |
| 6264989 | Spherical single-substance particles, medicines and foodstuffs containing the particles, and method of production thereof The present invention relates to a process for producing a spherical particle comprising an aggregate of particles containing at least 95% of a water-soluble single substance having a viscosity of 10 mPa.s or less as determined in the form of a saturated ... | 07/24/2001 |
| 6080429 | Method for drying microspheres A method for drying microspheres in a fluidized bed is provided, along with a composition comprising microspheres dried by that method.... | 06/27/2000 |
| 5958460 | Preparation process for a multiparticulate pharmaceutical form with plurality of sequences of controlled release Preparation process for a multiparticulate pharmaceutical form with a plurality of sequences of controlled release of the type which allows the body of the patient to be provided with a sufficient concentration of one or more active ingredients by one or ... | 09/28/1999 |
| 5888545 | Carbamazepine medicament with retarded active substance release An oral administration carbamazepine medicament with a retarded active substance release is disclosed. An aqueous plasticised polymer dispersion is applied on carbamazepine crystals without causing formation of carbamazepine dihydrate. The carbamazepine c... | 03/30/1999 |
| 5871775 | Controlled release pharmaceutical compositions for the oral administration containing nifedipine as active substance Controlled release pharmaceutical compositions for the oral administration of nifedipine are disclosed which comprise an amorphous coprecipitate of nifedipine and polyvinylpyrrolidone with suitable excipients. The release rate may be varied from 8 to 24 h... | 02/16/1999 |
| 5837292 | Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug A granulate, containing a drug having a solubility in water of 1:>10 and ࣘ15 weight percent of a water dispersible hydrocolloid incorporated into a fast-disintegrating and fast-dissolving composition.... | 11/17/1998 |
| 5792507 | Lactose spherical particles and process for their production To provide spherical particles made substantially from lactose and having high surface smoothness with low abrasiveness, and a process for their production. A process for producing spherical particles containing at least 95 wt % lactose, characterized by ... | 08/11/1998 |
| 5707636 | Apparatus and method for preparing solid forms with controlled release of the active ingredient Controlled release solid forms, apparatus and method for preparing solid forms for controlled release of an active ingredient.... | 01/13/1998 |
| 5618559 | Method of making modified-release metronidazole compositions Pharmaceutical compositions having a modified release profile for once daily dosing of metronidazole, methods for making the pharmaceutical compositions, and methods for treating a microbial infection with once daily dosing of the pharmaceutical compositi... | 04/08/1997 |
| 5609909 | Prolamine coatings for taste masking Prolamine fractions of grain proteins, applied as a single coating in weight ratios of 5 to 100% relative to the active substance being coated, result in the production of a liquid suspension which effectively masks the taste of orally administered drugs ... | 03/11/1997 |
| 5547683 | Method for producing microgranulated particle The present invention relates to a method for producing a microgranulated particle having particle size of not more than 0.2 mm, wherein a fine powder with the average particle size of not more than 10 .mu.m, which is being agitated, tumbled or fluidized,... | 08/20/1996 |
| 5436011 | Solid pharmaceutical dosage form and a method for reducing abrasion A method for reducing abrasion during film coating of susceptible solid dosage forms by applying to an uncoated dosage form, a subcoat containing a pharmaceutically acceptable polyalkylene glycol and the resulting solid pharmaceutical dosage form.... | 07/25/1995 |
| 5225238 | Method for coating active principles with a pH-sensitive polymer A new method of coating an active principle which comprises the step of coating an active principle with an aqueous emulsion or dispersion containing one or more pH-sensitive polymers.... | 07/06/1993 |
| 5158804 | Particle coating apparatus for small-scale processing Apparatus and methods are provided for coating relatively small quantities of particles including tablets, pellets, or granules. The device effectively fluidizes the particles to be coated by controlled vibration of a perforated platform through which dry... | 10/27/1992 |
| 5132142 | Apparatus and method for producing pellets by layering power onto particles An apparatus for layering powder onto particles has a vessel in which a rotor is mounted rotatable therein around a vertical axis. The rotor is a disc with a supporting surface for supporting particles. The apparatus also has a feeder with a substantially... | 07/21/1992 |