"Rail travel at high speeds is not possible because passengers, unable to breathe, would die of asphyxia."
Dionysius Lardner, Professor of Natural Philosophy and Astronomy at University College, London ; 1830
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| Number | Title | Issue Date |
| 8173196 | Method of coating a stent with a polysaccharide layer and associated stents The invention concerns methods of coating stents and stents produced in accordance therewith. The object of the invention is to provide methods of coating stents with a polysaccharide layer which has improved adhesion capacity on the substrate surface of the implant... | 05/08/2012 |
| 8173197 | Coated medical devices and methods of making same Methods of protecting an insertable medical device from chemical degradation are provided. Methods include coating the insertable medical device with an acrylic layer and then coating the acrylic layer with an acrylic-grafted fluoropolymer. Medical devices coated wi... | 05/08/2012 |
| 8163326 | Implantable or insertable medical devices visible under magnetic resonance imaging Disclosed is an implantable or insertable medical device comprising (a) a substrate and (b) a hydrogel polymer coating at a least a portion of the surface of the substrate, wherein the hydrogel polymer is adapted to render the medical device visible under magnetic r... | 04/24/2012 |
| 8163327 | Hydrophilic polymeric coatings for medical articles The invention provides a durable, lubricious coating for a medical article that can be prepared from a first polymer that is synthetic, soluble in a polar liquid, and having first reactive groups, and a second polymer that is synthetic, hydrophilic, and that include... | 04/24/2012 |
| 8153181 | Medical devices and related methods This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon. ... | 04/10/2012 |
| 8147897 | Cross-linkable polyionic coatings for medical devices A method for making an article comprising a core material and a coating thereon, the method comprising the steps of: (a) providing the core material; (b) applying one or more layers of a crosslinkable polycationic material, wherein the polycationic mat... | 04/03/2012 |
| 8142835 | Method for coating silicone hydrogels The invention relates to a process for producing biomedical articles, in particular, silicone hydrogel contact lenses having durable hydrophilic chitosan coating. The chitosan coating is covalently attached to the medical device by performing a crosslinking reaction... | 03/27/2012 |
| 8124166 | Method for loading nanoporous layers with therapeutic agent The present invention relates generally to medical devices with therapy eluting components and methods for making same. More specifically, the invention relates to implantable medical devices having at least one porous layer, and methods for making such devices, and... | 02/28/2012 |
| 8124165 | Pressurized dip coating system The present disclosure provides a method and apparatus for coating a medical device. ... | 02/28/2012 |
| 8124167 | Medical device with adherent coating, and method for preparing same A medical device such as a wire guide has a lubricious and/or therapeutic coating adhered to an etched, carbonaceous polymeric surface, for example a sodium-etched polymer surface. A method for preparing a lubricious and/or therapeutic coating on a medical device in... | 02/28/2012 |
| 8119183 | Method of doping surfaces Disclosed herein are methods of treating an article surface. The method comprises removing a metal oxide surface from the metal substrate to expose a metal surface; and delivering particles comprising a dopant from at least one fluid jet to the metal surface to impr... | 02/21/2012 |
| 8114464 | Hybrid thin films that incorporate lamellar phospholipid layer assemblies and transmembrane proteins The present disclosure provides various novel methods for forming hybrid thin films that contain multi-lamellar assemblies of phospholipid bilayers and can incorporate proteins, polypeptides, biological complexes, transmembrane proteins and other membrane-associated... | 02/14/2012 |
| 8110242 | Methods of preparing hydrogel coatings The present invention provides hydrogel coated, implantable medical devices and methods of coating hydrogels onto implantable medical devices. In one embodiment, a hydrogel coated medical device is formed by physically treating a surface of the medical device, chemi... | 02/07/2012 |
| 8097291 | Methods for coating workpieces The present invention is directed to methods, processes, and systems for coating portions of a workpiece as well as to workpieces that have themselves been coated in accord with the invention. Under these methods and processes of the invention, a means to repel may ... | 01/17/2012 |
| 8092854 | Method of attaching an antimicrobial cationic polyelectrolyte to the surface of a substrate A method of bonding an antimicrobial cationic polyelectrolyte to the surface of a substrate is described, wherein the antimicrobial thus attached to the substrate provides the substrate with antimicrobial properties, and at least a portion of the bonded antimicrobia... | 01/10/2012 |
| 8071155 | Medical devices and methods of making the same Medical devices, such as stents, and methods of making the devices are disclosed. In some embodiments, a method includes diffusing a first element into a first portion of the medical device. The first element includes carbon, hydrogen, nitrogen, oxygen, or combinati... | 12/06/2011 |
| 8062692 | Methods for using dental compositions containing fluorescent agents A method of applying a dental composition to tooth surfaces is provided. The dental composition, comprising polymerizable resin and fluorescing compound, is applied to a tooth surface and cured so that it hardens. The composition is preferably used as a dental seala... | 11/22/2011 |
| 8062691 | Method for treating medical devices using glycerol and an antimicrobial agent A non-metallic medical device treated with a antimicrobial agents is provided. Different combinations of antimicrobial agents can be used for different types of non-metallic medical devices depending on the types of infections related to each device. The combination... | 11/22/2011 |
| 8057842 | Method of contact coating a microneedle array A method of coating a microneedle array by applying a coating fluid using a flexible film in a brush-like manner. A method of coating a microneedle array comprising: providing a microneedle array having a substrate and a plurality of microneedles; providing a flexib... | 11/15/2011 |
| 8057841 | Mechanically attached medical device coatings The present invention relates to nanofibrous coatings on medical devices such a surgical mesh or stent, wherein the coating is mechanically attached to the device. The principal mechanism for attaching the coating is through causing the fibers to permeate and entang... | 11/15/2011 |
| 8048471 | Marked precoated medical device and method of manufacturing same A medical device, such as a medical wire, which includes a coating applied to the surface of the medical wire. The coating includes a base layer bonded to the surface of the medical wire and an at least partially transparent low-friction top coat applied to the base... | 11/01/2011 |
| 8043651 | System and method for coating a medical device A method and device for coating a medical device, such as a stent, including rolling the stent against a ribbon or gravure roll impregnated with coating material. The ribbon and gravure roll may include a recessed pattern matching a strut pattern of the stent. The s... | 10/25/2011 |
| 8025915 | Method of preparing a macromolecule deterrent surface on a pharmaceutical package A method of preparing a macromolecule deterrent surface on a pharmaceutical package. In particular, the present invention relates to a method of preparing a protein deterrent surface on a pharmaceutical package by applying a coating or coatings directly to the pharm... | 09/27/2011 |
| 8007855 | Method for coating implantable medical devices A method of coating an implantable medical device is disclosed, the method includes applying a composition onto the device and drying the composition at elevated temperature in an environment having increased relative humidity. ... | 08/30/2011 |
| 8007854 | Ceramic coating and method of preparation thereof A ceramic coating with gradient density/porosity and/or incorporated biologically active agents can be fabricated on the surface of substrates, including the surface of implantable medical devices. ... | 08/30/2011 |
| 8007856 | Mounting assembly for a stent and a method of using the same to coat a stent A mounting assembly for a stent and a method of coating a stent using the assembly are provided. ... | 08/30/2011 |
| 8003156 | Rotatable support elements for stents Various embodiments of methods and devices for coating stents are described herein. ... | 08/23/2011 |
| 7998523 | Open-pore biocompatible surface layer for an implant, methods of production and use The invention relates to open-pore biocompatible surface layers for implants, which layers are arranged over virgin surfaces of the implants, wherein pores of the open-pore surface layers are connected to form coherent pore networks and the surface layers have a spe... | 08/16/2011 |
| 7989018 | Fluid treatment of a polymeric coating on an implantable medical device A method for modifying a polymeric coating on an implantable medical device, such as a stent, is disclosed. The method includes application of a fluid to a wet or dry polymeric coating with and without drugs. ... | 08/02/2011 |
| 7985440 | Method of using a mandrel to coat a stent A method of applying a coating to a stent supported by a mandrel is disclosed. ... | 07/26/2011 |
| 7985442 | Patterned mold for medical device An apparatus and method for imprinting a pattern on a medical device to provide a surface with greater surface area and improved adhesion properties. ... | 07/26/2011 |
| 7985441 | Purification of polymers for coating applications Various embodiments of methods and devices for coating stents are described herein. Among these embodiments are methods of manufacturing an implantable medical device by purifying a polymer with a fluid capable of swelling the polymer, and subsequently coating a dev... | 07/26/2011 |
| 7981461 | Metallic bone implant having improved implantability and method of making the same An implantable device composed of a biocompatible material having an enhanced surface topography that has an implanted calcium ion concentration and method of making the same. ... | 07/19/2011 |
| 7972648 | Deposition of discrete nanoparticles on a nanostructured surface of an implant A method of forming an implant to be implanted into living bone is disclosed. The method comprises the act of roughening at least a portion of the implant surface to produce a microscale roughened surface. The method further comprises forming a nanoscale roughened s... | 07/05/2011 |
| 7955637 | Anti-microbial electrosurgical electrode and method of manufacturing same An electrosurgical device including a reinforcing underlayment having a non-stick, anti-microbial coating. In one embodiment, the coating includes a non-stick material having anti-microbial particles interspersed in the non-stick material. This coating is applied to... | 06/07/2011 |
| 7955636 | Antimicrobial coating Described herein are coatings containing water-soluble oligodynamic metal salts that are formulated and applied from hydrophobic solvents. In particular, articles of manufacture comprising polymer coatings containing oligodynamic metal salts can include hydrophobic ... | 06/07/2011 |
| 7951412 | Laser based metal deposition (LBMD) of antimicrobials to implant surfaces A method is provided for depositing a hard wear resistant surface onto a porous or non-porous base material of a medical implant. The wear resistant surface of the medical implant device may be formed by a Laser Based Metal Deposition (LBMD) method such as Laser Eng... | 05/31/2011 |
| 7935379 | Coated and imprinted medical devices and methods of making the same The present invention relates generally to coated medical devices, preferably a stent, that has a drug-eluting surface completely or partially coated with a coating that is imprinted with an impression. In particular, the invention is directed to a coated medical de... | 05/03/2011 |
| 7931932 | Processes for producing polymer coatings through surface polymerization A medical device with a therapeutic agent-releasing polymer coating. The medical device is provided by a method that comprises: (a) attaching at least one reactive species to a medical device surface, which reactive species leads to chain growth polymerization in th... | 04/26/2011 |
| 7931931 | Medicated porous metal prosthesis and a method of making the same A porous prosthesis for delivering a medication to the site of implantation, and a method of making the same, is disclosed. ... | 04/26/2011 |