...that after Walter Hunt patented the safety pin in 1849, he sold the rights to it for $400?
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| Number | Title | Issue Date |
| 8414957 | Non-fouling surfaces for reflective spheres The present invention relates to treating of reflective surfaces to prevent fouling. The present invention also relates to reflective materials treated to prevent fouling, as well as methods of using such reflective materials. ... | 04/09/2013 |
| 8414956 | Medicinal inhalation devices and components thereof A medicinal inhalation device having a non-metal coating applied by plasma deposition under ion bombardment conditions. ... | 04/09/2013 |
| 8394446 | Methods of providing antioxidants to implantable medical devices Methods of incorporating an antioxidant into a medical device including a polymer are described, and methods of packaging medical devices. ... | 03/12/2013 |
| 8389041 | Systems and methods for rotating and coating an implantable device A method for applying a coating to an implantable device is disclosed. The method includes positioning an implantable device relative to an ultrasonic material delivery apparatus. The implantable device is rotated at a relative speed. The relative speed may be more ... | 03/05/2013 |
| 8377499 | Methods of forming Poly(ester amide)-based drug delivery systems with controlled release rate and morphology A method of forming a coating on a medical device having a controlled morphology is described. ... | 02/19/2013 |
| 8377498 | Method for producing a medical device with a cross-linked hydrophilic coating Disclosed is a production method for medical devices with a hydrophilic coating, which ensures adequate adhesion to the substrate, as well as good water retention and low friction properties. Specifically, the method comprises providing a coating solution comprising... | 02/19/2013 |
| 8372468 | Surface modification to improve lubricity, abrasion resistance and temperature resilience of leads A medical electrical lead body having an outer surface and including at least one lumen having an inner surface treated with a silane surface modifying agent to form a three-dimensional, densely cross-linked lubricious coating over at least a portion of the inner su... | 02/12/2013 |
| 8361536 | Method for fixing antibody on the surface of medical instrument A method for fixing antibody on the surface of medical instrument, mainly includes: 1) pre-treating the instrument surface; 2) preparing holes: preparing multicrystal phase structure which has same size holes in the surface of the instrument by chemical corrosion, e... | 01/29/2013 |
| 8337936 | Implant and method for manufacturing same The present invention proposes a method for manufacturing an implant, in particular an intraluminal endoprosthesis, having a body such that the body has metallic material. To control the degradation in a desired time window, e.g., between four weeks and six months, ... | 12/25/2012 |
| 8323722 | Processing of biocompatible coating on polymeric implants The present invention provides polymeric substrates comprising a biocompatible coating and methods of preparation thereof. In particular, the coating may be a ceramic material, especially a calcium phosphate material, which may be functionally graded. The invention ... | 12/04/2012 |
| 8318235 | Method for applying drug coating to a medical device in surgeon room Medical devices, and in particular implantable medical devices such as stents and stent delivery systems including catheters, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organ... | 11/27/2012 |
| 8309161 | Aluminum oxide coated implants and components The invention provides a medical implant device or component thereof comprising a metal substrate, an intermediate coating, and an outer coating of aluminum oxide, as well as a method of making such a medical implant device or component thereof. ... | 11/13/2012 |
| 8298606 | Methods and compositions for stabilizing the myocardium The present invention provides materials and methods that can serve as a prosthetic and/or, for tissue engineer applications, as a supporting matrix in the stabilization of the myocardium. ... | 10/30/2012 |
| 8287938 | Method to produce a coating and to fine-tune the coating morphology This invention relates to a method to produce reproducible and homogeneous coatings and to fine-tune the coating morphology. More particularly, the invention relates to a method and apparatus for controlling the particle formation and deposition process to form a bi... | 10/16/2012 |
| 8287937 | Endoprosthese A coating having a smooth orange peel morphology is formed on an adluminal surface of a stent, concurrently with the formation of a coating having a rough rice grain morphology on an abluminal surface of the stent. During the formation of the two coatings, a mandrel... | 10/16/2012 |
| 8282979 | Method for coating medical devices An apparatus for coating medical devices at the point of care with a polymer and/or therapeutic agent comprising an environmentally controlled device coating chamber in which the device may be delivered by the manufacturer as the device packaging, or the device may ... | 10/09/2012 |
| 8277867 | Microdrop ablumenal coating system and method Systems and methods for coating medical devices are provided that allow for relatively precise control over the deposition area and coating uniformity with improved efficiency. A microdrop source is used to provide a flow of coating microdrops. A charging electrode ... | 10/02/2012 |
| 8273402 | Drug coated stent with magnesium topcoat A method for manufacturing a drug carrying stent includes applying at least a first therapeutic agent to at least an outer portion of a stent framework and applying a first magnesium coating on at least a first portion of the applied first therapeutic agent. ... | 09/25/2012 |
| 8268381 | Methods and systems for coating a medical device A coating system and method are described. In some embodiments, a system may include a composition. The composition may include one or more bridged polycyclic compounds. At least one of the bridged polycyclic compounds may include at least two cyclic groups, and at ... | 09/18/2012 |
| 8263169 | Stent mandrel fixture and method for reducing coating defects A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. ... | 09/11/2012 |
| 8257776 | Surface modification method and surface modified material A surface modification method includes a step of applying, onto a material, an application fluid containing a polymer having a functional group capable of producing a silanol group through hydrolysis thereof and an alkoxysilane and a step of applying, onto the mater... | 09/04/2012 |
| 8252361 | Implantable medical devices for local and regional treatment Implantable medical devices adapted to erodibly release delivery media for local and regional treatment are disclosed. ... | 08/28/2012 |
| 8247018 | Methods for quality control The present invention relates to method for quality control of surface coated objects used independently or in conjunction with product authentication; methods for assuring proper product handling; methods for assuring that product contents' match product's label, c... | 08/21/2012 |
| 8231927 | Marked precoated medical device and method of manufacturing same A method of manufacturing a coated medical device, such as a medical guide wire, including at least applying a first colored coating to at least a first portion of an outer surface of a medical guide wire, securing a first end of the medical guide wire, and for each... | 07/31/2012 |
| 8231926 | Marked precoated medical device and method of manufacturing same A medical device, such as a medical wire, which includes a coating applied to the surface of the medical wire. The coating includes a base layer bonded to the surface of the medical wire and an at least partially transparent low-friction top coat applied to the base... | 07/31/2012 |
| 8227016 | Laminated drug-polymer coated stent with dipped and cured layers The present invention provides a method of applying a drug-polymer coating on a stent. A stent framework is dipped into a first polymeric solution including a first polymer, a first therapeutic agent, and a first solvent. The polymeric solution is dried and the firs... | 07/24/2012 |
| 8216629 | Lubricious intraocular lens insertion device This invention relates to a method of making an intraocular lens insertion device comprising a lubricious insertion tip assembly and to the device itself. ... | 07/10/2012 |
| 8216630 | Porous biomaterials surface activation method The present invention relates to a porous biomaterials surface activation method by coating with a layer of apatitic nanocrystals in order to increase their surface reactivity. The method according to the invention is characterized by the following steps: a) prepari... | 07/10/2012 |
| 8197879 | Method for selectively coating surfaces of a stent A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. A method supporting a stent during the application of a coating substance is also provided. ... | 06/12/2012 |
| 8192785 | Apparatus and method for coating implantable devices A coating for implantable devices, such as stents, and a method of making the same is disclosed. Moreover, an apparatus for depositing the coating is disclosed. ... | 06/05/2012 |
| 8173197 | Coated medical devices and methods of making same Methods of protecting an insertable medical device from chemical degradation are provided. Methods include coating the insertable medical device with an acrylic layer and then coating the acrylic layer with an acrylic-grafted fluoropolymer. Medical devices coated wi... | 05/08/2012 |
| 8173196 | Method of coating a stent with a polysaccharide layer and associated stents The invention concerns methods of coating stents and stents produced in accordance therewith. The object of the invention is to provide methods of coating stents with a polysaccharide layer which has improved adhesion capacity on the substrate surface of the implant... | 05/08/2012 |
| 8163327 | Hydrophilic polymeric coatings for medical articles The invention provides a durable, lubricious coating for a medical article that can be prepared from a first polymer that is synthetic, soluble in a polar liquid, and having first reactive groups, and a second polymer that is synthetic, hydrophilic, and that include... | 04/24/2012 |
| 8163326 | Implantable or insertable medical devices visible under magnetic resonance imaging Disclosed is an implantable or insertable medical device comprising (a) a substrate and (b) a hydrogel polymer coating at a least a portion of the surface of the substrate, wherein the hydrogel polymer is adapted to render the medical device visible under magnetic r... | 04/24/2012 |
| 8153181 | Medical devices and related methods This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon. ... | 04/10/2012 |
| 8147897 | Cross-linkable polyionic coatings for medical devices A method for making an article comprising a core material and a coating thereon, the method comprising the steps of: (a) providing the core material; (b) applying one or more layers of a crosslinkable polycationic material, wherein the polycationic mat... | 04/03/2012 |
| 8142835 | Method for coating silicone hydrogels The invention relates to a process for producing biomedical articles, in particular, silicone hydrogel contact lenses having durable hydrophilic chitosan coating. The chitosan coating is covalently attached to the medical device by performing a crosslinking reaction... | 03/27/2012 |
| 8124166 | Method for loading nanoporous layers with therapeutic agent The present invention relates generally to medical devices with therapy eluting components and methods for making same. More specifically, the invention relates to implantable medical devices having at least one porous layer, and methods for making such devices, and... | 02/28/2012 |
| 8124165 | Pressurized dip coating system The present disclosure provides a method and apparatus for coating a medical device. ... | 02/28/2012 |
| 8124167 | Medical device with adherent coating, and method for preparing same A medical device such as a wire guide has a lubricious and/or therapeutic coating adhered to an etched, carbonaceous polymeric surface, for example a sodium-etched polymer surface. A method for preparing a lubricious and/or therapeutic coating on a medical device in... | 02/28/2012 |