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| Number | Title | Issue Date |
| 8070466 | Seamless capsule manufacturing apparatus In a seamless capsule manufacturing apparatus that ejects a droplet from a nozzle into hardening liquid to manufacture a seamless capsule SC, tube passages which are synthetic resin tubes are provided as flexible sections between pumps and the nozzle. The vibration ... | 12/06/2011 |
| 7766637 | Method and apparatus for the preparation of capsules An apparatus for a continuous encapsulation process is provided. The apparatus is a vibrating tubing used alone, in series, or in combination with an encapsulation apparatus, which is used alone or in series. The vibrating tubing is a flat coil, a standing spiral, o... | 08/03/2010 |
| 7452195 | Apparatus for preparation of aqueous emulsion from curable silicone composition and suspension of cured silicone particles Method for preparation of an aqueous emulsion from a curable silicone composition consisting of (A) an organopolysiloxane having at least two silicon-bonded hydroxyl groups, (B) an organohydrogensiloxane, and (C) a curing catalyst, said method being characterized by... | 11/18/2008 |
| 7377760 | Soft capsule manufacturing apparatus In a sheet forming part 2 of a soft capsule manufacturing apparatus 1, a drum drive system 27 which forms a gelatin sheet 13, and a pickup roller drive system 28 which peels off the gelatin sheet 13 are constructed to drive ... | 05/27/2008 |
| 7261529 | Apparatus for preparing biodegradable microparticle formulations containing pharmaceutically active agents This invention is directed to an apparatus and method for producing microparticles comprising pharmacologically active agents and biodegradable polymers. The apparatus includes a spinning disk containing a reservoir in the center thereof and a flat inclined surface.... | 08/28/2007 |
| 7247010 | Servo control for capsule making machine An encapsulation machine utilizes servo-driven components and a control system to control the encapsulation machine. Servomotors drive the fill supply mechanism, the die rollers and the casting drums. The control system uses a programmable controller to establish re... | 07/24/2007 |
| 7234290 | Process for producing aspheric seamless capsule and apparatus therefor In manufacturing an aspherical seamless capsule comprises, firstly, a seamless capsule C1 having a filler encapsulated with a shell membrane is provided, then it is dried in a dryer 12 until a predetermined percentage content of solvent in the shell me... | 06/26/2007 |
| 7048908 | Particles for inhalation having sustained release properties The invention generally relates to a method for pulmonary delivery of therapeutic, prophylactic and diagnostic agents to a patient wherein the agent is released in a sustained fashion, and to particles suitable for use in the method. In particular, the invention rel... | 05/23/2006 |
| 7045342 | Diagnostic detection device and method The invention provides an improved test cell for detecting the presence of an analyte in a liquid sample. The device has an elongate casing defining a liquid sample inlet, a reservoir volume, a test volume, and a window through the casing at the test volume. Dispose... | 05/16/2006 |
| 6989169 | Production of capsules and particles for improvement of food products The present invention is related to the production of capsules or particles of micro and nanometric size, for introduction into food, using stable electrified coaxial jets of two immiscible liquids with diameters in the micro and nanometric range. An aerosol of char... | 01/24/2006 |
| 6982095 | Capsules containing vital cells or tissues Capsules which contain vital cells or tissues as the contents and in which these cells or tissues can be grown. Since these cells or tissues can be grown in the capsules, an extremely high cell density can be achieved. By using these capsules, foods having an excell... | 01/03/2006 |
| 6958848 | Capsules, materials for use therein and electrophoretic media and displays containing such capsules An encapsulation material, intended for use in encapsulated electrophoretic displays, comprises the coacervation product of a polyanionic polymer having a vinyl main chain and a plurality of anionic groups bonded to the main chain, with a cationic or zwitterionic wa... | 10/25/2005 |
| 6855277 | Method and apparatus for liposome production A new method of producing liposomes is described using an in-line mixing system. The liposomes produced by this method find utility in numerous therapeutic applications. ... | 02/15/2005 |
| 6843942 | Method and device for producing lipid vesicles The invention relates to a device for producing lipid vesicles, which is equipped with a line (1) for transporting a polar liquid phase, with a line (2) for transporting an organic liquid phase containing lipids, with a collecting receptacle (7)... | 01/18/2005 |
| 6805818 | Apparatus and methods for forming patterned soft gelatin capsules An apparatus and a process useful for producing patterned gelatin ribbons for forming patterned soft gelatin capsules are disclosed. The apparatus and process use multiple spreader boxes to form a wide variety of possible patterns. ... | 10/19/2004 |
| 6638044 | Apparatus for forming composite pellets for the controlled release of the active ingredient in the treatment of humans or animals An apparatus for forming composite pellets containing active ingredients encapsulated in encapsulating material for the controlled release of the active ingredient in the treatment of humans, animals or plants that is capable of the following steps: produ... | 10/28/2003 |
| 6569363 | Apparatus and methods for forming patterned soft gelatin capsules An apparatus and a process useful for producing patterned gelatin ribbons for forming patterned soft gelatin capsules are disclosed. The apparatus and process use multiple spreader boxes to form a wide variety of possible patterns.... | 05/27/2003 |
| 6534018 | Method and apparatus for liposome production A new method of producing liposomes is described using an in-line mixing system. The liposomes produced by this method find utility in numerous therapeutic applications.... | 03/18/2003 |
| 6458296 | Method and device for capsulating microbial, plant and animal cells or biological and chemical substances The invention relates to a method for capsulating microbial, plant and animal cells or biological and chemical substances, using a nozzle to obtain small, especially spherical particles by vibrating an immobilisation mixture. According to said method, the... | 10/01/2002 |
| 6394945 | Radioactively coated devices This invention relates to radioactively coated devices, preferably radioactively coated medical devices. These coated devices are characterized as having a low rate of leaching of the radioisotope from the surface of the coated device and a uniform radioa... | 05/28/2002 |
| 6361298 | Methods and apparatus for making seamless capsules Apparatus for the production of seamless capsules in which capsule forming material passes from a heated carrier fluid to a cooled carrier fluid during formation and solidification of the capsules.... | 03/26/2002 |
| 6347930 | Device and method for manufacturing a segmented tubular capsule containing a biologically active medium A device for manufacturing tubular fibre includes an extrusion head through which a polymer and a biologically active material flow. The biologically active material is encapsulated within compartments formed in the fibre. Partial solidification is caused... | 02/19/2002 |
| 6318191 | Fluid sample testing system A sample testing system has a chamber sealing, apparatus adapted to receive a chamber containing a fluid sample material and to seal portions of a chamber into segments. A reagent injector cartridge actuator is adapted to receive a reagent injector cartri... | 11/20/2001 |
| 6174466 | Methods for making seamless capsules Method for the production of seamless capsules in which capsule forming material passes from a heated carrier fluid to a cooled carrier fluid during formation and solidification of the capsules.... | 01/16/2001 |
| 6022499 | Method for striping or marbleizing capsules An apparatus and a process useful for producing patterned gelatin ribbons for forming patterned soft gelatin capsules are disclosed. The apparatus and process use multiple spreader boxes to form a wide variety of possible patterns.... | 02/08/2000 |
| 5843334 | Method of producing emulsions and an emulsification apparatus There is provided a method of producing an emulsion by which an emulsion consisting of uniform and microfine globules can be easily obtained with a reduced energy input as compared with the conventional technology. This method of producing an emulsion comprise... | 12/01/1998 |
| 5827707 | Method for manufacturing minimal volume capsules containing biological materials The present invention provides methods and a device for producing minimal volume capsules containing viable cells or cellular aggregates. The methods and device use a two-phase aqueous emulsion system to form a dispersion of liquid capsule-forming materia... | 10/27/1998 |
| 5795506 | Method and system for controlling microcapsule particle diameters In a production line for microcapsules, which is provided with an emulsifying machine, an emulsion or microcapsules are automatically sampled on a on-line basis from a portion of a process pipeline, which portion is located downstream of the emulsifying m... | 08/18/1998 |
| 5672300 | Method for striping or marbleizing capsules An apparatus and a process useful for producing patterned gelatin ribbons for forming patterned soft gelatin capsules are disclosed. The apparatus and process use multiple spreader boxes to form a wide variety of possible patterns.... | 09/30/1997 |
| 5656469 | Method of encapsulating biological substances in microspheres A method for encapsulating biological substances in biocompatible microcapsules is disclosed, the method comprising: (a) maintaining a coating-forming liquid film sheet transverse to a vertical plane, said sheet comprising an organic polymerizable monomer ... | 08/12/1997 |
| 5558820 | Process for preparing microcapsules A process for the preparation of microcapsules having a wall membrane made of a polyurethane urea resin, which includes steps of mixing an oily solution and an aqueous solution, passing the resulting mixed solution through a clearance between an inner cyl... | 09/24/1996 |
| 5556580 | Liposome continuous size reduction method and apparatus A method of extruding liposomes from liposomal material comprising extruding the liposomal material through a frit, and apparatus for extrusion.... | 09/17/1996 |
| 5554382 | Methods and apparatus for making liposomes The present application features methods and apparatus for making liposomes with critical, supercritical or near critical fluids. The methods and apparatus combine a phospholipid and an aqueous phase, or multilamellar vesicles, with a critical, supercriti... | 09/10/1996 |
| 5453368 | Method of encapsulating biological substances in microspheres A method for encapsulating a biological substance is biocompatible microcapsules is disclosed, said method comprising: a) maintaining a coating-forming liquid film sheet comprising a solution of a soluble organic polymer in an organic solvent, b) causing dropl... | 09/26/1995 |
| 5440187 | Long life radioisotope-powered, voltaic-junction battery using radiation resistant materials An electric battery comprises: a nuclear source of relatively high energy radiation fluence; a semiconductor junction characterized by a curve for this fluence relating minority carrier diffusion length and a damage constant and; an enclosure having a suf... | 08/08/1995 |
| 5405558 | Method of manufacturing microcapsules A method for manufacturing microcapsules which prevents capsule particles from adhering to the inner wall surfaces of a wall-film-forming reactor device, thereby to eliminate the possibility that qualities of the microcapsule, such as the heat resisting, ... | 04/11/1995 |
| 5387093 | Apparatus for manufacturing seamless capsules An apparatus for manufacturing seamless capsules is provided with a multiple nozzle which blows multilayer liquid drops into a hardening liquid. The hardening liquid flows through a main flow path and an auxiliary flow path. The flow of hardening liquid t... | 02/07/1995 |
| 5271881 | Apparatus and method for making microcapsules An abrupt pressure change applied to a dispersion of core and shell material in a liquid carrier medium encapsulates the core material within the shell material. The method and apparatus of this invention permit a wider range of core and shell materials t... | 12/21/1993 |
| 5260621 | High energy density nuclide-emitter, voltaic-junction battery An electric battery comprises a semiconductor junction incorporating an inorganic crystalline compound of Group III and Group V elements of the Periodic Table characterized by a predetermined annealing temperature for defects therein; a nuclear source of ... | 11/09/1993 |
| 5254294 | Soft gelatin capsules In a dropping procedure for the formation of soft gelatin capsules in which, suitably, a pasty, fluid or sol/gel forming filling material is encapsulated with a soft gelatin mass, the solidification of the soft gelatin mass in a cooling bath of a chemical... | 10/19/1993 |