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| Number | Title | Issue Date |
| 8182806 | Synovial villi for use with tissue engineering Synovial villi derived explants and related surgical tools used to repair or prevent damage to injured or diseased tissue, including connective tissue. The tools including a harvesting tool for selectively harvesting synovial villi from the joint of patient and a de... | 05/22/2012 |
| 8178089 | Neuronal progenitors from feeder-free human embryonic stem cell culture The present invention relates to methods for producing feeder cell-free neuroprogenitor cells (preferably adherent) from embryonic stems cells, preferably human embryonic stem cells, the feeder cell-free neuroprogenitor cells, preferably human cells themselves, as w... | 05/15/2012 |
| 8173119 | Use of adipose-tissue cell fractions for post-irradiation tissue regeneration The present invention concerns the use of cells derived from the cellular fraction of the vascular stroma of the extramedullary adipose tissue to promote the regeneration of tissue following lesions caused by irradiation. More specifically, the use according to the ... | 05/08/2012 |
| 8168173 | CerCan: an energy supplement product for boosting the immune system This invention concerns the process of creating an energy supplement product, good also as an anti-aging, aphrodisiac and as an alternative source to prevent or to remedy some diseases. The product is a composition of five ingredients: four marine animals (sea cucum... | 05/01/2012 |
| 8168174 | Method of isolating human neuroepithelial precursor cells from human fetal tissue A method for isolating human neuroepithelial precursor cells from human fetal tissue by culturing the human fetal cells in fibroblast growth factor and chick embryo extract and immunodepleting from the cultured human fetal cells any cells expressing A2B5, NG2 and eN... | 05/01/2012 |
| 8163276 | Systems and methods for isolating and using clinically safe adipose derived regenerative cells Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and me... | 04/24/2012 |
| 8158122 | Mixed cell populations for tissue repair and separation technique for cell processing The present invention provides a fluid exchange cell culture technique and tissue repair cells (TRCs) made by these methods, as well as methods using these cells. The method includes a new wash step which increases the tissue repair properties of the TRCs of the inv... | 04/17/2012 |
| 8147824 | Immunomodulatory properties of multipotent adult progenitor cells and uses thereof Isolated cells are described that are not embryonic stem cells, not embryonic germ cells, and not germ cells. The cells can differentiate into at least one cell type of each of at least two of the endodermal, ectodermal, and mesodermal lineages. The cells do not pro... | 04/03/2012 |
| 8142773 | Methods of implanting mesenchymal stem cells for tissue repair and formation The invention relates to methods of isolating and implanting mesenchymal stem cells for tissue repair or formation, without prior culture expansion of the mesenchymal stem cells. In particular, the invention relates to methods of isolating mesenchymal stem cells fro... | 03/27/2012 |
| 8142774 | Methods of treatment using electromagnetic field stimulated stem cells Methods of modifying stem cells and compositions of modified stem cells, in particular mesenchymal stem cells, using electric or electromagnetic fields. In various embodiments, the present invention's methods are for the treatment of a human or other mammal subject ... | 03/27/2012 |
| 8137665 | Systemic non-nodular endosymbiotic nitrogen fixation in plants Non-leguminous crops, e.g. wheat, maize and rice, do not form nodules and are dependant for their nutrition on fixed nitrogen from the soil, or from chemical/nitrogenous fertilizers. The present invention provides non-leguminous plants and leguminous plants, includi... | 03/20/2012 |
| 8128923 | Renal carcinoma cell line and uses thereof The present invention relates to a renal carcinoma cell line capable of activating the immune system in an antigen-specific manner. According to a further aspect, the invention also includes derivatives of the cell line that maintain said activation capacity. The in... | 03/06/2012 |
| 8128924 | Methods for using a three-dimensional stromal tissue to promote angiogenesis The present invention relates to a method for promoting blood vessel formation in tissues and organs. In particular, the method relates to implantation or attachment of an engineered three-dimensional stromal tissue to promote endothelialization and angiogenesis in ... | 03/06/2012 |
| 8124071 | Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells The invention provides novel methods of reducing transplant rejection and cardiac allograft vasculopathy in humans by employing the implantation of autologous progenitor cells into the transplanted donor heart. The autologous progenitor cells can be vascular progeni... | 02/28/2012 |
| 8119122 | Use of gingival fibroblasts for vascular cell therapy The invention relates to the use of gingival fibroblasts for obtaining a cellular composition for treating arterial-remodelling pathology, for example an aneurysm, post-cryoplasty stenosis and restenosis, an aortic dissection or atherosclerosis. ... | 02/21/2012 |
| 8119121 | Autologous adipose tissue implant with concentrated stem cells Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a ... | 02/21/2012 |
| 8119123 | Compositions comprising vascular and myocyte progenitor cells and methods of their use The invention provides compositions of adult cardiac vascular progenitor cells (VPCs) and adult cardiac myocyte progenitor cells (MPCs) useful for the treatment of various cardiac conditions. The invention also encompasses methods of generating a biological bypass, ... | 02/21/2012 |
| 8110185 | Method for preventing and treating cardiovascular diseases with BRCA1 Methods for inhibiting cardiomyocyte apoptosis and/or to improving cardiac function and inhibiting inflammation-induced apoptosis in endothelial cells by delivering BRCA1 are provided. Such methods are useful in treatment and prevention of cardiovascular diseases. | 02/07/2012 |
| 8110184 | Ex vivo and in vivo methods and related compositions for generating hematopoietic stem cell populations Various embodiments provide methods and related compositions for increasing the population size of hematopoietic stem cells (HSCs) in patients that may benefit from reconstitution of stem cells and/or differentiated cells of the blood lineage. The present methods en... | 02/07/2012 |
| 8105582 | Tumour vaccine comprising allogenic or xenogeneic tumour cells The present invention provides a composition for the treatment of a tumor, comprising: (i) allogeneic or xenogeneic tumor cells; and (ii) a pharmaceutically acceptable excipient. If two or more heterozygous individuals have the same cancer/tumor of the same or simil... | 01/31/2012 |
| 8105580 | Methods of using adipose derived stem cells to promote wound healing Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be pr... | 01/31/2012 |
| 8105581 | Compositions and methods for inducing neuronal differentiation The present invention provides compositions and methods for inducing neuronal cell differentiation. ... | 01/31/2012 |
| 8097248 | Mite composition, use thereof, method for rearing the phytoseiid predatory mite , rearing system for rearing said phytoseiid mite and methods for biological pest control on a crop The present invention relates to a novel mite composition comprising a population of the phytoseiid predatory mite species Amblyseius swirskii. and a factitious host population, which may be employed for rearing said phytoseiid predatory mite species or for r... | 01/17/2012 |
| 8088370 | Compositions and methods of vascular injury repair The present invention relates to pharmaceutical compositions comprising a chemotactic hematopoietic stem cell product comprising an enriched population of CD34+ cells containing a subpopulation of cells having chemotactic activity, methods of preparing these composi... | 01/03/2012 |
| 8075880 | Compositions and methods for regulating angiogenesis In accordance with the present invention, EC progenitors can be used in a method for regulating angiogenesis, i.e., enhancing or inhibiting blood vessel formation, in a selected patient and in some preferred embodiments for targeting specific locations. For example,... | 12/13/2011 |
| 8075881 | Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also provided are methods of isolation and culture, as well as therapeutic us... | 12/13/2011 |
| 8048411 | Co-transplantation of hepatic stellate cells and islet cells A method of inhibiting graft rejection includes isolating Hepatic Stellate Cells from a mammal liver, activating the isolated Hepatic Stellate Cells, and administering a combination of Hepatic Stellate cells and a graft to a mammal. ... | 11/01/2011 |
| 8043614 | Autogenic living scaffolds and living tissue matrices: methods and uses thereof The present invention is drawn to a 3-dimensional cell-produced scaffold construct comprising fibroblasts and the extracellular matrix that has been produced and arranged by these cells. The constructs promote the differentiation, dedifferentiation and/or transdiffe... | 10/25/2011 |
| 8038991 | High-viscosity hyaluronic acid compositions to treat myocardial conditions Embodiments of single component bioscaffolding systems formed of a hydrogel such as hyaluronic acid or salt thereof are described. The hyaluronic acid or salt thereof may be dissolved in a buffer, plasma, or combination thereof to minimize adverse immunogenic respon... | 10/18/2011 |
| 8034335 | High-titer retroviral packaging cells The present invention relates to non-replicative recombinant retrovirus packaging cells able to grow in suspension in a serum-free medium. In particular, the present invention relates to a human embryonic 293SF-based cell line stably expressing gag and pol gene prod... | 10/11/2011 |
| 8034334 | Immunotherapy with in vitro-selected antigen-specific lymphocytes after non-myeloablative lymphodepleting chemotherapy A method of promoting the regression of a cancer in a mammal comprising: (i) administering to the mammal nonmyeloablative lymphodepleting chemotherapy, and (ii) subsequently administering: (a) autologous T-cells, which have been previously isolated, selected for hig... | 10/11/2011 |
| 8029780 | Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same The present invention relates to stem cells which exhibit increased sensitivity to a chemoattractant and, more particularly, to methods of generating and using them such as in clinical applications involving stem cell transplantation. ... | 10/04/2011 |
| 8017112 | Transplantation of bone marrow stromal cells for treatment of neurodegenerative diseases The present invention relates to a treatment of an autoimmune demyelinating disease/disorder. Also included in the present invention is the use of bone marrow stromal cells for the treatment of multiple sclerosis (MS). ... | 09/13/2011 |
| 8007784 | Antigenic modulation of cells The present invention is directed to a non-immunogenic cellular composition comprising: a cell having a cell surface and antigenic determinants on the cell surface; an optional linker molecule covalently attached to the cell surface; and a hydrophilic, biocompatible... | 08/30/2011 |
| 7994131 | Stimulation of proliferation of pluripotential stem cells through administration of pregnancy associated compounds The present invention provides for a method for stimulating the proliferation of pluripotential stem cells in a mammal comprising administration of pregnancy related compounds more particularly human chorionic gonadotropin, leutenizing hormone or prolactin. The pres... | 08/09/2011 |
| 7988962 | Use of polysulphated alginate in cellular matrices The present invention describes an in vitro/ex vivo method for the cultivation of connective tissue cells or progenitor cells (e.g. chondrogenic cells) in matrix comprising polysulphated alginate. These cultivated cells can be used in the preparation of a medicament... | 08/02/2011 |
| 7985408 | Tenocyte cell culturing method The present invention relates to a method for culturing tenocytes. In particular the present invention relates to a method for culturing tenocytes comprising the step of incubating tenocytes in a culture medium comprising insulin or functional derivative. ... | 07/26/2011 |
| 7968088 | Internally administered therapeutic agents for cranial nerve diseases comprising mesenchymal cells as an active ingredient Intravenous administration of bone marrow cells collected from rat bone marrow or peripheral blood to a rat cerebral infarction model was found to be effective in treating cerebral infarction. Human and murine bone marrow stem cells showed similar effects. Mesenchym... | 06/28/2011 |
| 7951364 | CaR receptor as a mediator of migratory cell chemotaxis and/or chemokinesis This invention relates to methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention relates to methods and compositions for modulating movement of CaR receptor expressing cells of hematopoietic, ne... | 05/31/2011 |
| 7947269 | Mite composition, use thereof, method for rearing a phytoseiid predatory mite, rearing system for rearing said phytoseiid predatory mite and methods for biological pest control on a crop The present invention relates to a novel mite composition comprising a population of a phytoseiid predatory mite species and a factitious host population, which may be employed for rearing said phytoseiid predatory mite species or for releasing the pyrltoseiid preda... | 05/24/2011 |
