Quotables
"Inventing is a combination of brains and materials. The more brains you use, the less material you need."
Charles Kettering
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8147804 | Method and device for isolating a chemically and radiochemically cleaned Ga-radionuclide and for marking a marking precursor with the Ga-radionuclide The invention relates to initial 68Ge/Ga-generator elute which is guided directly to a cation exchanger, whereon 68Ga is quantitatively absorbed and is cleaned simultaneously in a chemical and radio chemical manner. Subsequently, the 68 | 04/03/2012 |
| 8003079 | Core and core-shell nanoparticles containing iodine for X-ray imaging Nanoparticles having an average particle size of less than 2000 nm, wherein said nanoparticles comprise a polymer having pendant cleavable iodine substituted groups are provided. Processes for preparing the nanoparticles and their use as a contrast agent for X-ray i... | 08/23/2011 |
| 7981400 | Shiga toxin B-subunit as a vector for tumor diagnosis and drug delivery to GB3 expressing tumors The invention relates to new compounds for cancer therapy or diagnosis and more specifically to the use of a non-toxic B subunit of Shiga toxin mutant as a vector for diagnostic products or drugs in over-expressing Gb3 receptor cells, such compounds havin... | 07/19/2011 |
| 7811551 | Imaging agents The invention relates to compounds of formula (I): and their use as targeting vectors that bind to receptors associated with angiogenesis. Such compounds may thus be used for diagnosis or therapy of, for example, malignant diseases, heart diseases, endometriosis, in... | 10/12/2010 |
| 7731940 | Compositions and methods related to serotonin 5-HT1A receptors Contemplated substituted arylpiperazinyl compounds, and most preferably 18F-Mefway, exhibit desirable in vitro and in vivo binding characteristics to the 5-HT1A receptor. Among other advantageous parameters, contemplated compounds retain high binding affi... | 06/08/2010 |
| 7713517 | Compositions and methods for enhancing contrast in imaging Example compositions of liposomes with hydrophilic polymers on their surface, and containing relatively high concentrations of contrast-enhancing agents for computed tomography are provided. Example pharmaceutical compositions of such liposomes, when administered to... | 05/11/2010 |
| 7708979 | Thermogelling polymer blends for biomaterial applications Thermogelling polymers are described containing poly (n-isopropyl acrylamide). Solutions of this polymer, copolymers or mixtures of the polymer with a second polymer such as poly(ethylene glycol), poly (vinyl pyrrolidone) or poly(vinyl alcohol) are liquids at room t... | 05/04/2010 |
| 7704488 | Dendritic and star-shaped contrast agents for medical devices and bioabsorbable radiopaque bulk material and method for producing same In accordance with the present invention, a high intensity radiopaque contrast agent is disclosed. The agent may be coated on or incorporated within bulk materials, which may then be subsequently utilized to fabricate a radiopaque medical device. Primary effects thr... | 04/27/2010 |
| 7582283 | Contrast agents to improve gastrointestinal tract opacification during abdominal and pelvic CT scans Methods of imaging a portion of a body of a patient are provided. In the methods, a contrast agent including an iso-osmotic contrast agent is administered to the patient. In a preferred embodiment, the iso-osmotic contrast agent comprises polyethylene glycol (PEG) a... | 09/01/2009 |
| 7498018 | Contrast media for use in medical and diagnostic procedures and methods of using the same The present invention relates to contrast media having a low concentration of contrast agent (active ingredient) and/or low Hounsfield value for use in medical or diagnostic procedures, or for therapeutic use. In one alternative embodiment, the contrast media are co... | 03/03/2009 |
| 7465434 | Diagnosis of blood clots using fibrin-binding proteins bound with contrast agents This invention describes how to modify a fibrin-binding protein, such as tPA, with a contrast agent, such as iodine. This substance could then be given to a patient suspected of having a blood clot by an intravenous route, and then detected by a radiographic study a... | 12/16/2008 |
| 7438894 | Dyes for organ function monitoring Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for opti... | 10/21/2008 |
| 7427391 | Formulations for use in medical and diagnostic procedures The present invention relates to formulations for use in medical or diagnostic procedures comprising a stabilizing agent alone or in combination with an osmotic agent. In one embodiment, the stabilizing agent is a natural hydrocolloid, preferably locust bean gum, an... | 09/23/2008 |
| 7427389 | Diagnostic agents for positron emission imaging using radiolabeled halogenated xanthenes New diagnostic agents for positron emission tomography (PET) and methods for use of such agents for imaging of human or animal tissue are described, wherein a primary active component of such agents is a radiolabeled halogenated xanthene or halogenated xanthene deri... | 09/23/2008 |
| 7407647 | Organic radiographic contrasting agents for medical devices The present invention discloses an organic radiographic contrasting agent containing an aliphatic or alicyclic backbone and multiple halogen-substituted aromatic groups. Each of the halogen-substituted aromatic groups in the radiographic contrasting agent is substit... | 08/05/2008 |
| 7402299 | Intracorporeal medicaments for photodynamic treatment of disease New intracorporeal photodynamic medicaments and certain medical uses and methods for use of such photodynamic medicaments for treatment of disease in human or animal tissue are described, wherein a primary active component of such medicaments is a halogenated xanthe... | 07/22/2008 |
| 7387772 | Chimeric, human and humanized anti-CSAP monoclonal antibodies The present invention provides humanized, chimeric and human anti-CSAp antibodies and anti-CSAp antibody fusion proteins that are useful for the treatment and diagnosis of various cancers, including colon cancer. ... | 06/17/2008 |
| 7384624 | Oral contrast and method of producing the oral contrast Oral contrast compositions are used as an aid for CAT scans and are ideally fast-flowing and good tasting for assisting in quick preparation of a patient in today's extremely active and busy emergency rooms. An oral contrast used for CAT scans of the esophagus, stom... | 06/10/2008 |
| 7384623 | High energy phototherapeutic agents High energy phototherapeutic agents or radiosensitizer agents comprised of a halogenated xanthene, or other related agents that exhibit a preference for concentration in biologically sensitive structures in diseased tissue, and methods of treating and imaging using ... | 06/10/2008 |
| 7385041 | Dual functioning excipient for metal chelate contrast agents A novel dual functioning excipient for metal chelate contrast agents is disclosed. The present excipient, Xm[X′(L′)]n, which is the calcium or zinc salt of the calcium or zinc complex of an organic ligand, enhances safet... | 06/10/2008 |
| 7378081 | Composition and method for direct visualization of the human appendix A positive contrast agent composition containing meglumine diatrizoate, sodium diatrizoate, simethicone, famotidine and aspartame in predetermined amounts that is orally administered to a patient for clinical evaluations of appendicitis wherein a positive contrast e... | 05/27/2008 |
| 7371714 | Chemical agent decontamination composition comprising a perfluorinated alkyl bromide A composition and methods of use for the decontamination of chemical agents, including chemical warfare agents. The decontamination composition is nontoxic, nonflammable and non-corrosive and includes an effective amount of a perfluorinated alkyl bromide or reactive... | 05/13/2008 |
| 7364748 | Controlled morphologies in polymer drug for release of drugs from polymer films The present invention includes a drug release system. The drug release system comprises a bulk polymer phase and a polymeric drug-enriched phase within the bulk polymer phase. At least one drug is incorporated into the drug-enriched phase. ... | 04/29/2008 |
| 7354416 | Methods and devices for draining fluids and lowering intraocular pressure Methods, devices and systems for draining fluid from the eye and/or for reducing intraocular pressure. A passageway (e.g., an opening, puncture or incision) is formed in the lamina cribosa or elsewhere to facilitate flow of fluid from the posterior chamber of the ey... | 04/08/2008 |
| 7354432 | Red to near-infrared photobiomodulation treatment of the visual system in visual system disease or injury A method of treating visual system disease is disclosed. One embodiment comprises the steps of (a) exposing a component of a patient's visual system to light treatment, wherein the light treatment is characterized by wavelength of between 630-1000 nm and power inten... | 04/08/2008 |
| 7344705 | Composition comprising low density microspheres Low density microspheres, methods for preparing same, and use of same as contrast agents are described. The microspheres have a void which contains a gas or the vapor of a volatile liquid selected from the group consisting of aliphatic hydrocarbons, chlorofluorocarb... | 03/18/2008 |
| 7338652 | Methods for positron emission imaging with radiolabeled halogenated xanthenes diagnostic agents New diagnostic agents for positron emission tomography (PET) and methods for use of such agents for imaging of human or animal tissue are described, wherein a primary active component of such agents is a radiolabeled halogenated xanthene or halogenated xanthene deri... | 03/04/2008 |
| 7335391 | Method for coating implantable devices A method of forming a coating for an implantable medical device, such as a stent, is provided which includes applying a composition to the device in an environment having a selected pressure. ... | 02/26/2008 |
| 7329413 | Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof Coatings for implantable medical devices, and methods for fabricating thereof, are provided. The coatings include a first polymer layer and a second polymer layer, where the second polymer has a higher degree of hydration than the first polymer. ... | 02/12/2008 |
| 7330535 | X-ray flux management device The invention is directed to an x-ray flux management device that adaptively attenuates an x-ray beam to limit the incident flux reaching a subject and radiographic detectors in potentially high-flux areas while not affecting the incident flux and detector measureme... | 02/12/2008 |
| 7329402 | Methods of imaging and treatment Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The... | 02/12/2008 |
| 7320784 | Immobilized labeling compounds and methods The invention includes methods and compounds for labelling conjugates with metals which comprise the steps of coupling the conjugate to a support surface; introducing a complex-forming metal to the support; and collecting the metal-conjugate complex released from th... | 01/22/2008 |
| 7321881 | Methods and systems for predicting occurrence of an event Embodiments of the present invention are directed to methods and systems for training a neural network having weighted connections for classification of data, as well as embodiments corresponding to the use of such a neural network for the classification of data, in... | 01/22/2008 |
| 7318932 | Coatings for drug delivery devices comprising hydrolitically stable adducts of poly(ethylene-co-vinyl alcohol) and methods for fabricating the same A polymer coating for medical devices based on a derivatized poly(ethylene-co-vinyl alcohol) is disclosed. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include poly(ethylene-co-vinyl a... | 01/15/2008 |
| 7311980 | Polyactive/polylactic acid coatings for an implantable device A polymeric coating for a medical device that comprises poly(lactic acid) and a block copolymer including blocks of poly(ethylene glycol) and poly(butylene terephthalate) is provided. ... | 12/25/2007 |
| 7306786 | Calcium phosphate cements comprising a water-soluble contrast agent Methods are provided for producing flowable compositions, e.g. pastes, that set into calcium phosphate products and include a contrast agent. In the subject methods, dry reactants that include a calcium source and a phosphate source are combined with setting fluid a... | 12/11/2007 |
| 7306785 | Multifunctional cross-bridged tetraaza macrocyclic compounds and methods of making and using A multifunctional cross-bridged tetraaza macrocyclic compound has at least one side arm that comprises a moiety that is capable of forming a bond with another molecule, which has a targeting moiety that directs the compound to a site a marker substance. The compound... | 12/11/2007 |
| 7288244 | Determining vulnerable plaque in blood vessels The invention is based on the realisation that inflamed plaques in blood vessel walls, which are potentially vulnerable to rupture, can be detected at elevated temperatures which are lower than previously realised. In particular, the low temperatures at which inflam... | 10/30/2007 |
| 7279174 | Stent coatings comprising hydrophilic additives A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically... | 10/09/2007 |
| 7270800 | Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition This invention relates to novel thioflavin derivatives, methods of using the derivatives in, for example, in vivo imaging of patients having neuritic plaques, pharmaceutical compositions comprising the thioflavin derivatives and method of synthesizing the compounds.... | 09/18/2007 |
