...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 7041281 | Natural feel polymers Natural feel polymers exhibit an advantageous blend of flexibility and a strong affinity to natural fibers imparting a natural feel when applied to keratin-based fibers, e.g. hair, skin, or textiles, e.g. cotton, wool, and are water-soluble and water-resistant. The ... | 05/09/2006 |
| 7018625 | Personal care compositions Personal care compositions, particularly hair care products, include a polymer mixture made from (A) a derivatized polymer of maleic anhydride having defined repeat units of a monomer (e.g. α-olefin) maleic anhydride alkyl half-ester or full acid, maleamic acid and... | 03/28/2006 |
| 7005125 | Personal care products Personal care products, particularly hair care products, are made herein by mixing (A) a polymer having defined repeat units of a monomer (e.g. α-olefin) maleic anhydride alkyl half-ester or full acid, maleamic acid and maleimide, which is derivatized with an amine... | 02/28/2006 |
| 6911197 | N-maleimidyl polymer derivatives The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded t... | 06/28/2005 |
| 6692732 | Ionic polymers as toxin-binding agents A method for treating pathogenic toxins in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising a cationic group attached to the polymer backbone. The polymer can be a homopolymer or a c... | 02/17/2004 |
| 6602498 | N-maleimidyl polymer derivatives The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being direct... | 08/05/2003 |
| 6482392 | Aerosol antimicrobial compositions An aerosol antimicrobial composition is provided with the following ingredients: a) an anionic polymer or prepolymer; (b) a quaternary ammonium compound, the components (a) and (b) combining to form an antimicrobially effective complex; (c) at least one w... | 11/19/2002 |
| 6331296 | Food additives which affect conformationally altered proteins An assay comprises contacting cells containing a conformationally altered protein with test compound and determining if the altered protein is cleared. The cells may be scrapie-infected neuroblastoma cells. Another assay comprises contacting organ or tiss... | 12/18/2001 |
| 6290947 | Ionic polymers as toxin-binding agents A method for treating pathogenic toxins in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising a cationic group attached to the polymer backbone. The polymer can be a homopolymer or a c... | 09/18/2001 |
| 6190688 | Material for elimination or detoxification of super antigens A material with excellent selective absorption of super antigens. Said material contains urea bonds or thiourea bonds and remains active even in a high protein concentration solution in the neutral region, Activity remains after sterilization. Also provid... | 02/20/2001 |
| 6080387 | Aerosol antimicrobial compositions An aerosol antimicrobial composition is provided with the following ingredients: a) an anionic polymer or prepolymer; (b) a quaternary ammonium compound, the components (a) and (b) combining to form an antimicrobially effective complex; (c) at least one w... | 06/27/2000 |
| 6015551 | Copolymers of carboxylic acids and multiply olefinically unsaturated carboxylic acid derivatives and their use as thickeners and dispergents The disclosure relates to a copolymer obtainable by radically initiated polymerization of the following: A) 70-99.9 wt. % an olefinically unsaturated C3 -C5 monocarboxylic acid, an olefinically unsaturated C4 -C8 | 01/18/2000 |
| 5928633 | Material for elimination or detoxification of super antigens A material with excellent selective absorption of super antigens. Said material contains urea bonds or thiourea bonds and remains active even in a high protein concentration solution in the neutral region, Activity remains after sterilization. Also provid... | 07/27/1999 |
| 5902589 | Method for treating hydratable polymers, compositions obtained therefrom, and methods of using same Aqueous solutions of hydratable polymers are prepared by hydrating a hydratable polymer in water without agitation sufficient to shear the molecular structure of the polymer thereby maintaining intact the polymer's molecular structure thereby providing a ... | 05/11/1999 |
| 5869099 | Cosmetic composition with polymer-bound benzophenone chromophores A cosmetic composition comprises a polymer with the repeating structural unit (I) ##STR1## where R and R' can be identical or different and are H, alkali metal, ammonium, C1 -C30 alkyl, X is a direct linkage, C1 -C | 02/09/1999 |
| 5736128 | Cosmetic composition for rejuvenation of skin without skin irritation A cosmetic composition for rejuvenating the appearance of skin with reduced or minimal potential for skin irritation, in the form of a lotion, creme, solution or gel, includes an aqueous, alcoholic or aqueous-alcoholic solution of a polymer having a carbo... | 04/07/1998 |
| 5679366 | Pesticide or herbicide polymer complexes for forming aqueous dispersions Various liquid or low melting pesticide and herbicide formulations, previously formulated with organic solvents, are combined with a polymer in solution and co-precipitated to form a polymer complex which captures the pesticide or herbicide yet exists as ... | 10/21/1997 |
| 5668111 | Sustained-release preparation A sustained-release preparation which comprises a physiologically active peptide of general formula ##STR1## wherein X represents an acyl group; R1, R2 and R4 each represents an aromatic cyclic group; R3 re... | 09/16/1997 |
| 5626858 | Pesticide or herbicide polymer complexes for forming aqueous dispersions Various liquid or low melting pesticide and herbicide formulations, previously formulated with organic solvents, are combined with a polymer in solution and co-precipitated to form a polymer complex which captures the pesticide or herbicide yet exists as ... | 05/06/1997 |
| 5514670 | Submicron emulsions for delivery of peptides The present invention provides emulsions comprising a plurality of submicron particles, a bioactive peptide, and an aqueous continuous phase or that effect enhanced oral bioavailability of the peptide. Another aspect of the invention provides compositions... | 05/07/1996 |
| 5488075 | Contraceptive for use by a male The present invention relates to a contraceptive for use by a male. The contraceptive consists of a copolymer of styrene maleic anhydride which is prepared by the step of irradiation at a dose of 0.2 to 0.24 megarad for every 40 gms. of the copolymer. The... | 01/30/1996 |
| 5480868 | Sustained-release preparation A sustained-release preparation which comprises a physiologically active peptide of general formula ##STR1## wherein X represents an acyl group; R1, R2 and R4 each represents an aromatic cyclic group; R3 re... | 01/02/1996 |
| 5476662 | Pesticide or herbicide polymer complexes for forming aqueous dispersions Various liquid or low melting pesticide and herbicide formulations, previously formulated with organic solvents, are combined with a polymer in solution and co-precipitated to form a polymer complex which captures the pesticide or herbicide yet exists as ... | 12/19/1995 |
| 5462738 | Copper hydroxide dry flowable bactericide/fungicide and method of making and using same There is disclosed a granular copper hydroxide dry flowable bactericide/fungicide having improved biological activity and a method for making and using same. A bactericide/fungicide is made by forming a homogeneous aqueous slurry containing between approx... | 10/31/1995 |
| 5425939 | Thickened cosmetic compositions Thickened cosmetic compositions are provided based upon a thickening system that includes sclerotium gum and a hydrophobically-modified acrylate or methacrylate copolymer. The relative weight ratio of sclerotium gum to the polymer may range from about 1:1... | 06/20/1995 |
| 5393798 | Hydrogel material and method of preparation Hydrogel materials suitable for use in bandages and the like have been made from modified copolymers of poly(methyl vinyl ether/maleic anhydride). The modifying groups are three to seven carbon amines, amides or alcohols having a terminal vinyl group whic... | 02/28/1995 |
| 5389366 | Neocarzinostatin derivative composition for oral administration A composition for oral administration to cancer patients includes a neocarzinostatin derivative and from 0.1 and 100 ml per mg of the neocarzinostatin derivative of at least one fatty acid glyceride which has from 6 to 20 carbon atoms and which is noniodi... | 02/14/1995 |
| 5378456 | Antitumor mitoxantrone polymeric compositions An antitumor polymeric composition comprising an anthracene antitumor compound, particularly mitoxantrone, covalently conjugated to, or admixed with, a divinyl ether-maleic anhydride (MVE) copolymer and methods of treating solid tumors and inducing regres... | 01/03/1995 |
| 5320838 | Protectant for irritated skin containing polyethyleneglycols, polyvinylether salt anhydride and polyvinylpyrrolidone A smooth, greaseless skin ointment especially prepared for irritated skin, which protects, adheres and simultaneously is easily washable without causing skin damage. The ointment base is a blend of polyethylene glycols. It is combined with a bioadhesive w... | 06/14/1994 |
| 5298253 | Copper hydroxide dry flowable bactericide/fungicide and method of making and using same There is disclosed a granular copper hydroxide dry flowable bactericide/fungicide having improved biological activity and a method for making and using same. A bactericide/fungicide is made by forming a homogeneous aqueous slurry containing between approx... | 03/29/1994 |
| 5292517 | pH sensitive, reversible gelling, copolymeric erodible drug delivery system pH sensitive, reversible gelling erodible drug delivery compositions and methods for their production are disclosed. The compositions are liquid solutions of poly(methylvinylether/maleic acid) having pharmaceutical compounds incorporated therein. The poly... | 03/08/1994 |
| 5206009 | Non-aerosol, low voc, pump hair spray composition A non-aerosol, low VOC, pump hair spray composition containing dimethoxymethane as cosolvent is described herein. The composition is applied by the user as a fine spray mist which dries rapidly on the hair, and provides a low curl droop and effective curl... | 04/27/1993 |
| 5185143 | Terpolymer hair fixative resins prepared by solution polymerization of maleic anhydride, vinyl acetate and isobornyl acrylate What is described herein is solution polymerization in acetone solvent of a monomer mixture of maleic anhydride, vinyl acetate and isobornyl acrylate or methacrylate.... | 02/09/1993 |
| 5173298 | Nonaqueous fluorinated drug delivery vehicle suspensions Nonaqueous pharmaceutical compositions for use in aqueous physiological systems are disclosed comprising drug delivery vehicles suspended in nonaqueous perfluorocarbon or fluorinated silicone liquid carriers. The suspended drug delivery vehicles may be wa... | 12/22/1992 |
| 5173290 | Hair fixatives A hair treating method for imparting curl retention to hair in which at least one film forming ingredient is applied to the hair. The improvement utilizes as the film forming ingredient an interpenetrating polymer network that contains an organosilicon co... | 12/22/1992 |
| 5158766 | Storage stable aqueous soluble germicidal film forming composition A single-part aqueous, storage stable, antimicrobial film-forming composition comprising a major portion of water, an antimicrobially effective amount of a cationic germicidal agent having the structure (R) (R1) (R2) (R3) ... | 10/27/1992 |
| 5047238 | Adjuvants for vaccines An efficacious parenterally administered inactivated canine coronavirus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent canine coronavirus is produced. A method for propaga... | 09/10/1991 |
| 5032386 | Antiplaque antibacterial oral composition An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, about 0.25-0.35% by weight of a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichlor... | 07/16/1991 |
| 4774082 | Volatile insect repellents This invention relates to volatile insect repellent compositions comprising an insect repellent, such as deet, and specific maleic anhydride/alpha olefin polymers to increase the residual activity of the insect repellent.... | 09/27/1988 |
| 4536206 | Miticidal composition and method for controlling spider mites A miticidal composition comprising a water-soluble acidic high polymer electrolyte of branching crosslinked polymer having a plurality of carboxyl groups as active ingredient and an aqueous medium is effective for various spider mites without causing chem... | 08/20/1985 |