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| Number | Title | Issue Date |
| 7332164 | Heterobifunctional polymeric bioconjugates Heterobifunctional polymeric prodrug platforms for delivering biologically active compounds, including proteins, monoclonal antibodies and the like are disclosed. One preferred compound is Methods of making and u... | 02/19/2008 |
| 7199098 | Copolymer-1 improvements in compositions of copolymers The present invention relates to an improved composition of copolymer-1 comprising copolymer-1 substantially free of species having a molecular weight of over 40 kilodaltons. ... | 04/03/2007 |
| 7067146 | Food compositions and methods of preparing the same The present invention concerns a food composition having a foodstuff and substantially pure eritadenine. The invention also concerns a food additive having a liquid or solid material intended to be added to a foodstuff, said material being supplemented with substant... | 06/27/2006 |
| 6939539 | Copolymer-1 improvements in compositions of copolymers The present invention relates to an improved composition of copolymer-1 comprising copolymer-1 substantially free of species having a molecular weight of over 40 kilodaltons. ... | 09/06/2005 |
| 6740641 | Sugar derivatives of hydromorphone, dihydromorphine and dihydromorphine, compositions thereof and uses for treating or preventing pain Glucoside and glucuronide derivatives of hydromorphone, dihydromorphine, and dihydroisomorphine and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising a glucoside or glucuronide derivative of hydromorphone, dihydromorphine, or dihydroi... | 05/25/2004 |
| 6620847 | Copolymer-1 improvements in compositions of copolymers The present invention relates to an improved composition of copolymer-1 comprising copolymer-1 substantially free of species having a molecular weight of over 40 kilodaltons.... | 09/16/2003 |
| 6464971 | Anionic or cationic dendrimer antimicrobial or autiprotozoan compositions To inhibit, prophylactically or therapeutically, a bacterial, yeast, fungal, or parasitic agent in a patient, an effective amount of a dendrimer is administered to the patient, which dendrimer has a plurality of terminal groups, at least one of which has ... | 10/15/2002 |
| 6328953 | Polymeric derivatives of camptothecins The invention relates to polymeric conjugates of 20-O-[glycyl-aminoacyl-glycyl]-camptothecins and a process for producing the same.... | 12/11/2001 |
| 6296842 | Process for the preparation of polymer-based sustained release compositions The invention relates to a sustained release composition and methods of forming and using said composition for the sustained release of biologically active agent. The sustained release compositions of the invention comprise a biocompatible polymer and a b... | 10/02/2001 |
| 6190650 | Antiviral dendrimers An antiviral compound comprises a dendrimer such as a polyamidoamine or polyly sine dendrimer having a plurality of terminal groups, wherein at least one of the terminal groups has an anionic- or cationic-containing moiety bonded thereto, particularly a s... | 02/20/2001 |
| 6126932 | Polymer bound carbodiimide coupling reagent This invention provides novel 5-HT1F agonists of Formula ##STR1## where X, R1, R2, and R3 are defined in the specification, which are useful for the treatment of migraine and associated disorders.... | 10/03/2000 |
| 6048898 | Copolymer-1 improvements in compositions of copolymers The present invention relates to an improved composition of copolymer-1 comprising copolymer-1 substantially free of species having a molecular weight of over 40 kilodaltons.... | 04/11/2000 |
| 5989535 | Polymeric bioadhesive emulsions and suspensions and methods of treatment Bioadhesive/mucoadhesive composition in a suspension or emulsion form that delivers drugs to the target tissue in a sustained manner is formulated. A composition, method of manufacture and its application in treatment of mammalian tissue are disclosed. Th... | 11/23/1999 |
| 5981589 | Copolymer-1 improvements in compositions of copolymers The present invention relates to an improved composition of copolymer-1 comprising copolymer-1 substantially free of species having a molecular weight of over 40 kilodaltons.... | 11/09/1999 |
| 5869099 | Cosmetic composition with polymer-bound benzophenone chromophores A cosmetic composition comprises a polymer with the repeating structural unit (I) ##STR1## where R and R' can be identical or different and are H, alkali metal, ammonium, C1 -C30 alkyl, X is a direct linkage, C1 -C | 02/09/1999 |
| 5800808 | Copolymer-1 improvements in compositions of copolymers The present invention relates to an improved composition of copolymer-1 comprising copolymer-1 substantially free of species having a molecular weight of over 40 kilodaltons.... | 09/01/1998 |
| 5720950 | Polymers containing antifibrotic agents, compositions containing such polymers, and methods of preparation and use The present invention concerns a method for treating fibrotic conditions by administration of an effective amount of an antifibrotic agent. The antifibrotic agent is preferably a proline analog, such as cis-4-hydroxy-L-proline (cHyp). The antifibrotic age... | 02/24/1998 |
| 5516881 | Aminoxyl-containing radical spin labeling in polymers and copolymers Aminoxyl-containing radical is provided in polymers and copolymers by replacing a hydroxyl moiety in a carboxyl group at a chain end of a starting material biodegradable polymer or copolymer with imino or oxy linked to aminoxyl-containing radical to form ... | 05/14/1996 |
| 5364638 | Antimicrobial material for breeding or keeping fish and process for producing the same An antimicrobial material for fish breeding or keeping comprising a formed article of a pulp and/or polyolefin base material and a process for producing the same are disclosed, in which said formed article contains a functional group having a function of ... | 11/15/1994 |
| 5252673 | Macromolecular mitomycin C derivative and method for production thereof A macromolecular mitomycin derivative excellent in antitumor ability is produced by causing a specific divinyl ether-maleic anhydride copolymer to react with a specific aminocarboxylic acid and causing mitomycin C to react on the resultant reaction produc... | 10/12/1993 |
| 5242684 | Antimicrobial, low toxicity, non-irritating composition comprising a blend of bis-quaternary ammonium compounds coprecipitated with a copolymer of vinylpyrrolidone and an acrylamido or vinyl quaternary ammonium monomer An antimicrobial, low toxicity, non-irritating composition comprises a blend of several bis-quaternary ammonium compounds coprecipitated with a copolymer of vinylpyrrolidone and an acrylamido or vinyl quaternary ammonium monomer.... | 09/07/1993 |
| 5200471 | Biomolecules covalently immobilized with a high bound specific biological activity and method of preparing same A biologically active adduct support, prepared from an azlactone-functional polymeric support and biomolecules covalently immobilized thereon, is disclosed. The biomolecules are covalently immobilized in the presence of polyanionic salt using a method whi... | 04/06/1993 |
| 5079004 | Antimicrobial superabsorbent compositions and method An antimicrobial superabsorbent composition of a cross-linked hydrophilic sodium salt form of a partially neutralized acrylic acid-based polymer gel having covalently bonded thereto a silane. The composition can be in the form of flakes, strips, powders, ... | 01/07/1992 |
| 5035892 | Antimicrobial superabsorbent compositions and methods An antimicrobial superabsorbent composition of a cross-linked hydrophilic sodium salt form of a partially neutralized acrylic acid-based polymer gel having covalently bonded thereto a silane. The composition can be in the form of flakes, strips, powders, ... | 07/30/1991 |
| 4990338 | Antimicrobial superabsorbent compositions and methods An antimicrobial superabsorbent composition of a cross-linked hydrophilic sodium salt form of a partially neutralized acrylic acid-based polymer gel having covalently bonded thereto a silane. The composition can be in the form of flakes, strips, powders, ... | 02/05/1991 |
| 4755379 | Polymers substituted by groups conferring anti-coagulant properties on them, process for their preparation, articles and compositions made therefrom and uses thereof Anticoagulant products are constituted by polymers (homopolymers or copolymers) including in their chain substitutable groups on which are fixed statistically, groups X and/or Y and/or V, where X denotes the group --SO3 R1 or --R | 07/05/1988 |
| 4705683 | Pharmaceutical compositions Pharmaceutical compositions comprising mixtures of a histamine H2 -receptor antagonist such as cimetidine or ranitidine and sodium polyacrylate in a specified range of ratios have been found to exhibit synergistic effects in an in vivo test mod... | 11/10/1987 |
| 4481167 | Sanitizing complexes of polyoxazolines or polyoxazines and polyhalide anions The title complexes comprise (a) a poly-2-oxazoline or poly-2-oxazine, such as the homopolymers of polymerized 2-ethyl-2-oxazoline or 2-ethyl-2-oxazine, and (b) IBrCl- or polyhalide anion of the formula (XY2n)- where X a... | 11/06/1984 |
| 4261973 | Allergen-containing substances This invention pertains to allergen-containing substances, methods of preparing the same and using the same as immunologically specific suppressants of the production of reaginic antibodies directed to the allergen in question. The allergen-containing sub... | 04/14/1981 |
| 4220565 | Immunochemical conjugates: method and composition Techniques for preparing stable conjugates of protein-D-GL which can then be isolated in pure form are disclosed, using hen egg ovalbumin (OVA) as a prototype protein, and conjugation and purification methods are described which involve (1) application of... | 09/02/1980 |
| 4003990 | Anti-inflammatory polymers, pharmaceutical compositions containing the same and process for producing said polymers A polymer has on its macromolecular chains in the form of a lateral branching an anti-inflammator residue having a carboxylic acid function chemically linked to the macromolecular chains by an intermediate covalent function.... | 01/18/1977 |
| 3997660 | Soluble hydrophilic polymers and process for producing the same Soluble, hydrophilic polymers suitable for medical use and as blood plasma substitutes comprising low molecular weight polymer derived from at least one monomer of an acrylamide type material or a mono-ester of an acrylic type acid and a glycol which is c... | 12/14/1976 |
| 3954967 | Method of producing microcolloidal aqueous emulsions of unsaturated organic insecticidal compounds A method of reducing the micelle size of an aqueous emulsion of an unsaturated organic compound utilizes an ionic pumping action to achieve micelle division. The resin utilized is selected on the basis of the presence in the molecular chain of a high numb... | 05/04/1976 |