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| Number | Title | Issue Date |
| 8187583 | Oil-in-water emulsions Improved oil-in-water emulsions are provided and a method for their manufacture. In particular, the emulsions comprise a means to control delivery of oil-soluble or water-soluble actives in a core comprising a liquid oil or gel oil continuous phase, which actives ca... | 05/29/2012 |
| 7438900 | Dendritic encapsulation of active agents A pharmaceutical composition comprising an active agent bound to a scaffold for dendritic encapsulation wherein said scaffold is covalently or non-covalently attached to a polysaccharide. More specifically, the invention is directed to active agent complexes or conj... | 10/21/2008 |
| 7375083 | Pharmaceutical compositions for prevention of overdose or abuse The invention relates to pharmaceutical compositions comprised of a chemical moiety attached to an active agent in a manner that substantially decreases the potential of the active agent to cause overdose or to be abused. When delivered at the proper dosage the phar... | 05/20/2008 |
| 7375082 | Abuse-resistant hydrocodone compounds The present invention decreases the potential for abuse of opioids, particularly hydrocodone, by covalent modification. The invention provides methods of delivering hydrocodone as conjugates that release the hydrocodone following oral administration while being resi... | 05/20/2008 |
| 7192966 | Pharmaceutical composition A pharmaceutical composition comprising an analgesic or analgesic combination and a stool softener is disclosed. The analgesic is selected from morphine, meperidine, fentanyl, hydromorphone, oxymorphone, oxycodone, hydrocodone, methadone, propoxyphene, pentazocine, ... | 03/20/2007 |
| 7087223 | Preventives and/or remedies for hyperphosphatemia Provided in a phosphate ion adsorbent containing a weakly basic anion exchange resin as an active ingredient which aims at providing preventives and/or remedies for hyperphosphatemia having a high selectivity for the adsorption of phosphate ion and showing an effect... | 08/08/2006 |
| 6692732 | Ionic polymers as toxin-binding agents A method for treating pathogenic toxins in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising a cationic group attached to the polymer backbone. The polymer can be a homopolymer or a c... | 02/17/2004 |
| 6491903 | Particles comprising amphiphilic copolymers Provided are methods of inhibiting bile acid uptake from the gastrointestinal system and reducing blood serum cholesterol by administering to a mammal, such as a human, an effective amount of particles comprising amphiphilic copolymers, having a crosslink... | 12/10/2002 |
| 6387362 | Adsorbent for bradykinin, method for eliminating the same by adsorption, and adsorber An adsorbent or bradykinin comprising styrene-divinylbenzene copolymer having sulfonic acid groups and a method for adsorbing and removing bradykinin comprising contacting the adsorbent with a fluid containing bradykinin are provided. An adsorber for adso... | 05/14/2002 |
| 6383500 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications Provided are particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain. Also provided are compositions comprising such particles, including pharmaceutical compositions, methods of making the present particl... | 05/07/2002 |
| 6290947 | Ionic polymers as toxin-binding agents A method for treating pathogenic toxins in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising a cationic group attached to the polymer backbone. The polymer can be a homopolymer or a c... | 09/18/2001 |
| 5888526 | Antibacterial antifungal agent and fibrous material containing the same The present invention is to provide a fibrous material containing an antibacterial antifungal agent consisting of specific metal salt of organic compound effective for both antibacterial and antifungal functions and various articles containing the same fi... | 03/30/1999 |
| 5811436 | Oral liquid compositions containing paroxetine resinate An oral liquid pharmaceutical composition comprising a paroxetine-Amberlite IRP88 complex.... | 09/22/1998 |
| 5719265 | Polymer-bound paclitaxel derivatives A polymer conjugate consisting essentially of: from 90 to 99.9 mol % of units represented by the formula ##STR1## from 0.1 to 5 mol % of units represented by the formula ##STR2## wherein one of R1 and R2 is a copolymer resi... | 02/17/1998 |
| 5575993 | Ionene polymers containing biologically-active anions Ionene polymers having biologically-active organic and/or inorganic anions are described. Methods to prepare the ionene polymers, compositions containing them and their methods of use are also described.... | 11/19/1996 |
| 5368852 | Prolonged-release liquid type of pharmaceutical preparation comprising drug-resin complex and benzoate preservative The present invention provides a prolonged-release liquid type of pharmaceutical preparation prepared by coating a pharmaceutically active drug-ion exchange resin complex which was treated previously with an impregnating agent, with a water permeable diff... | 11/29/1994 |
| 5288503 | Cryogel oral pharmaceutical composition containing therapeutic agent An oral pharmaceutical composition comprising a hydrophobic resin or ion exchange resin which has a therapeutic agent bound thereto forming an agent-resin complex is disclosed. The complex is coated with a water-permeable diffusion barrier of poly(vinyl a... | 02/22/1994 |
| 5071646 | Pharmaceutical ion exchange resin composition An ion exchange resin composition which is readily dispersible in water is provided. This resin composition comprises a granulated ion exchange resin, a pharmacologically active ingredient bound thereto with a sugar or sugar alcohol, and a sufficient amou... | 12/10/1991 |
| 5032393 | Drug adsorbates The bitter taste of ranitidine may be masked by forming an adsorbate with a synthetic cation exchange resin. The adsorbate is particularly suitable for use in pharmaceutical compositions for oral administration such as chewable or suckable tablets, granul... | 07/16/1991 |
| 4996047 | Sustained release drug-resin complexes Disclosed are oral pharmaceutical preparations which comprise a pharmacologically active drug bound to small particles of an ion-exchange resin to provide a drug-resin complex having a drug content above a specified value. The drug-resin complex is subseq... | 02/26/1991 |
| 4781920 | Anthelmintic paste compositions containing resinates of d1-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole The invention provides physically stable anthelmintic paste compositions containing resinates of d1-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole and other anthelmintic compounds in combination with a wide variety of therapeutic agents such as an... | 11/01/1988 |
| 4587242 | Sulfonic resins having a therapeutical activity, preparation thereof and pharmaceutical compositions containing them A pharmaceutical compound characterized by a delayed release of the therapeutically active component, comprising a sulfonic type ion exchange resin and cis(b1;)-3-acetyloxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyp henyl)-1,5-benzothiazep... | 05/06/1986 |
| 4369175 | Process for the manufacture of prolonged action vincamine preparations, the vincamine preparations so obtained, and medicaments containing them The invention relates to a process for the manufacture of prolonged action and stable vincamine preparations, which process comprises reacting an acid addition salt of vincamine with an alkali metal salt or alkaline earth metal salt of a sulfonic acid cat... | 01/18/1983 |