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| Number | Title | Issue Date |
| 8147816 | Presbyopia treatment by lens alteration Embodiments of the present invention relate to methods and pharmacological or biological compositions to treat presbyopia in the human eye. According to the embodiments, pharmacological or biological compositions may be applied to or injected into an eye to effect a... | 04/03/2012 |
| 8119112 | Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid Ophthalmic compositions that comprise 0.1 ppm to 10 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof; 0.005 wt. % to 0.15 wt. % of hyaluronic a... | 02/21/2012 |
| 8043607 | UV-absorbers for ophthalmic lens materials Dihydroxybenzotriazole UV absorbing compounds that are particularly useful in ophthalmic devices are disclosed. ... | 10/25/2011 |
| 7993634 | Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods Biocompatible intraocular implants, such as microparticles, include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be a... | 08/09/2011 |
| 7985405 | Treatment solution and method for preventing posterior capsular opacification by selectively inducing detachment and/or death of lens epithelial cells A treatment solution used to prevent posterior capsular opacification is applied or introduced into the lens capsular bag before, during, or after cataract surgery. The treatment solution comprises an ion transport mechanism interference agent, which either alone or... | 07/26/2011 |
| 7976833 | Ophthalmic surgical irrigating solutions containing hyaluronidase and method for preventing post-operative intraocular pressure increases An ophthalmic irrigating solution containing hyaluronidase and an antioxidant is provided. The solution prevents a post-operative intraocular pressure rise when used during an ophthalmic surgical procedure, and also protects corneal endothelial cells. A method for p... | 07/12/2011 |
| 7935332 | Presbyopia treatment by lens alteration This invention effects a change in the accommodation of the human lens affected by presbyopia through the use of various reducing agents that change accommodative abilities of the human lens, and/or by applying energy to affect a change in the accommodative abilitie... | 05/03/2011 |
| 7875270 | Treatment solution and method for preventing posterior capsular opacification by selectively inducing detachment and/or death of lens epithelial cells A treatment solution used to prevent posterior capsular opacification is applied or introduced into the lens capsular bag before, during, or after cataract surgery. The treatment solution may also be applied to an intraocular lens prior to surgery. The treatment sol... | 01/25/2011 |
| 7875271 | Ophthalmic composition comprising xanthan gum and glucose The present invention provides an ophthalmic composition containing xanthan gum and glucose, which has a superior corneal epithelial disorder-treating effect. ... | 01/25/2011 |
| 7871602 | Use of bis-amines to enhance the antimicrobial activity of aqueous compositions The use of bis-amines to enhance the antimicrobial activity of pharmaceutical compositions is described. The bis-amines are particularly useful for enhancing the antimicrobial activity of aqueous ophthalmic compositions, such as artificial tears or ocular lubricants... | 01/18/2011 |
| 7803359 | UV-absorbers for ophthalmic lens materials UV absorbing compounds that are particularly useful in ophthalmic devices are disclosed. ... | 09/28/2010 |
| 7785578 | Non-invasive ocular drug delivery The present invention is drawn to a pharmaceutical compound for the treatment of posterior retinal diseases through topical application of the compound. The compound includes an effective amount of a therapeutic compound, and at least one additional agent that helps... | 08/31/2010 |
| 7744860 | Reduced bioirritant composition A method for reducing irritancy of ascorbic acid administered to a biological surface for anti-angiogenic, anti-oxidant, anti-inflammatory and other effects. It has been discovered that pH neutralized ascorbic acid retains the efficacy of non-pH neutralized ascorbic... | 06/29/2010 |
| 7618619 | Colored visco-elastic composition The invention relates to a visco-elastic composition for use in ocular surgery and to a method of using said composition. Specifically, the present visco-elastic composition comprises a visco-elastic substance and at least one vital dye. The invention enables a visu... | 11/17/2009 |
| 7618620 | Ophthalmic compositions containing a synergistic combination of three polymers Ophthalmic compositions suitable for use as artificial tears or as vehicles for ophthalmic drugs are disclosed. The compositions contain a combination of three polymers that have a synergistic effect on viscosity. ... | 11/17/2009 |
| 7569212 | Procedure and composition of treatment and/or care of the eye A procedure for the manufacture of contact lenses for eye treatment, eye protection and eye-care wherein the lenses are impregnated with a suitable composition, a composition for the impregnation of a contact lens for the treatment and/or care and/or protection of t... | 08/04/2009 |
| 7445771 | Use of bis-amines to enhance the antimicrobial activity of aqueous compositions The use of bis-amines to enhance the antimicrobial activity of pharmaceutical compositions is described. The bis-amines are particularly useful for enhancing the antimicrobial activity of aqueous ophthalmic compositions, such as artificial tears or ocular lubricants... | 11/04/2008 |
| 7429483 | Use of nerve growth factor for the storage, culture or treatment of cornea The nerve growth factor (NGF) is used for the storage of corneas in culture, for the production and the storage in vitro of single cell populations of the corneal morphological and functional unit (i.e. epithelium, stroma/keratocytes and endothelium) and of the conj... | 09/30/2008 |
| 7393824 | Methods of peptide preparation The present invention relates to a method of producing a bioactive peptide, wherein the peptide is 7 to 25 amino acids in length, has at least 3 cationic amino acids and is capable of forming an amphipathic α-helix, which method comprises identification of a cation... | 07/01/2008 |
| 7393522 | Physiologically balanced, ionized, acidic solution and methodology for use in wound healing Described herein is a physiologically-balanced, acidic solution. Typically the solution is prepared by a chemical reactions or by the electrolysis of a solution comprising a mixture of an inorganic salt to form a physiologically balanced solution. This invention als... | 07/01/2008 |
| 7381404 | Treatment for dry macular degeneration The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a t... | 06/03/2008 |
| 7364723 | Liquid preparation for contact lenses A highly safe liquid preparation for contact lenses which contains 0.3 to 50 ppm of a polyamine having recurring units of the formula (I): wherein n is 0 or 1, and which has a high antibacterial effect even at low concentra... | 04/29/2008 |
| 7363928 | Dilution resistant viscoelastic compositions A method of performing intra-articular therapy and a dilution resistant viscoelastic composition are disclosed. One embodiment of the dilution resistant composition comprises a hyaluronate-based viscoelastic agent and a low viscosity, polymer-containing solution. Th... | 04/29/2008 |
| 7361368 | Device and method for combining a treatment agent and a gel A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first an... | 04/22/2008 |
| 7354574 | Treatment of ocular disease A method and article to treat ocular disease with Cyclosporin A alone or with compounds related to Cyclosporin A for intraocular injection or implantation. Treatment does not result in ocular toxicity and encompasses age related macular degeneration, retinitis pigme... | 04/08/2008 |
| 7351407 | Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (CTGF) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies The present invention provides a method for lowering intraocular pressure and providing neuroprotection to a patient in need thereof by administering a therapeutically effective amount of at least one non-nucleotide or non-protein agent that inhibits expression and/... | 04/01/2008 |
| 7338976 | Heterocyclic esters or amides for vision and memory disorders This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using heterocyclic esters and amides. ... | 03/04/2008 |
| 7332528 | DRI nasal sprays There are provided safe, tasteless, odorless, non-aqueous liquid spray compositions formulated for administration to the nasal cavity consisting essentially of pharmacologically acceptable non aqueous liquid carrier in which said bioactive material is directly insol... | 02/19/2008 |
| 7332470 | Methods and compositions for treating ocular disease The use of collectins and/or surfactant proteins for the treatment and prevention of ocular disease. ... | 02/19/2008 |
| 7329411 | Ophthalmic compositions containing a synergistic combination of three polymers Ophthalmic compositions suitable for use as artificial tears or as vehicles for ophthalmic drugs are disclosed. The compositions contain a combination of three polymers that have a synergistic effect on viscosity. ... | 02/12/2008 |
| 7306802 | Ophthalmic compositions containing a synergistic combination of three polymers Ophthalmic compositions suitable for use as artificial tears or as vehicles for ophthalmic drugs are disclosed. The compositions contain a combination of three polymers that have a synergistic effect on viscosity. ... | 12/11/2007 |
| 7300667 | Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract Disclosed are compositions comprising antiseptic and wound healing agents for the treatment of diseases of the lower respiratory tract and methods. ... | 11/27/2007 |
| 7282221 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 10/16/2007 |
| 7276619 | Vitreoretinal silicone tamponades made by supercritical fluid extraction A process for the purification of a silicone oil or fluid using neat supercritical carbon dioxide or a supercritical carbon dioxide mixture extraction to produce vitreoretinal silicone tamponades. The subject process is an economical, highly effective, reproducible,... | 10/02/2007 |
| 7276255 | Wound and ulcer treatment with super-oxidized water Super-oxidized water based on hypochlorous acid, such as is obtained by the electrochemical treatment of a saline solution, may be used in the treatment of leg ulcers or other open wounds. Preferably, the pH of the super-oxidized water is in a range of 4 to 7, and t... | 10/02/2007 |
| 7265150 | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders This invention relates to novel compositions and uses of N-heterocyclic carboxylic acids and carboxylic acid isosteres for treating a vision disorder, improving vision, treating memory impairment or enhancing memory performance in an animal. ... | 09/04/2007 |
| 7265117 | Topical brimonidine tartrate formulations that lack chlorine dioxide Topical solution compositions of brimonidine tartrate are disclosed. The solution compositions lack an oxidative preservative. ... | 09/04/2007 |
| 7247270 | Method and composition for reducing contact lens swelling The present invention is directed to an ophthalmic solution for soft contact lenses for controlled release of polyethers into an eye's tear film. Polyether components of the subject solution are released from the soft contact lens material matrix over long time peri... | 07/24/2007 |
| 7244440 | Ophthalmic compositions containing a synergistic combination of three polymers Ophthalmic compositions suitable for use as artificial tears or as vehicles for ophthalmic drugs are disclosed. The compositions contain a combination of three polymers that have a synergistic effect on viscosity. ... | 07/17/2007 |
| 7238678 | Adhesive N,O-carboxymethylchitosan coatings which inhibit attachment of substrate-dependent cells and proteins The present invention relates to a method of inhibiting cellular and protein attachment to substrates by applying a composition containing an effective amount of adherent N,O-carboxymethylchitosan to a substrate with such that cellular and protein attachment are pre... | 07/03/2007 |
