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| Number | Title | Issue Date |
| 8025903 | Composite bone graft substitute cement and articles produced therefrom The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 t... | 09/27/2011 |
| 7976874 | Injectable calcium phosphate cements and the preparation and use thereof A calcium phosphate cement suitable for use in dental and bone prosthesis is disclosed, which include calcium phosphate particles having a diameter of 0.05 to 100 microns, wherein said calcium phosphate particles on their surfaces have whiskers or fine crystals havi... | 07/12/2011 |
| 7910136 | Nutritional supplement for osteoarthritis The present invention relates to a method of treating osteoarthritis by administering a mineral composition in the form of a nutritional supplement, where the mineral composition may contain Smectite, Gypsum, Quartz, Feldspar, Jarosite, Kaolinite and/or Zeolite.... | 03/22/2011 |
| 7858124 | Anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalyt... | 12/28/2010 |
| 7780994 | Composite biomaterials comprising calcium phospate materials, collagen and glycosaminoglycans A process for the production of a composite material comprising collagen, brushite and one or more glycosaminoglycans, said process comprising the steps of providing an acidic aqueous solution comprising collagen, a calcium source and a phosphorous source and one or... | 08/24/2010 |
| 7771755 | Injectable calcium phosphate solid rods and pastes for delivery of osteogenic proteins Osteogenic proteins are delivered via an injectable solid rod or hardenable paste. The formulation comprises a calcium phosphate material, an osteogenic protein, and optional additives and active ingredients such as a bone resorption inhibitor. Methods of making inj... | 08/10/2010 |
| 7758896 | Porous calcium phosphate networks for synthetic bone material A porous composition comprising a hydroxyapatite material, as can be made from a mixture of calcium phosphate, calcium oxide and a removable inorganic porogen. In other embodiments, the present invention provides a method of making such a porous hydroxyapatite mater... | 07/20/2010 |
| 7754246 | Composite bone graft substitute cement and articles produced therefrom The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 t... | 07/13/2010 |
| 7709029 | Calcium-containing restoration materials A bone or dental implant material in the form of a paste includes a mixture of calcium phosphate and/or calcium-containing powders, liquid glycerol, organic acid and gelling agent. The paste is stable, resistant to washout and will harden upon exposure to water. Phy... | 05/04/2010 |
| 7704529 | Magnesium-substituted hydroxyapatites A stable, phase-pure magnesium-substituted crystalline hydroxyapatite containing from about 2.0 to about 29 wt % magnesium, wherein at least 75 wt % of the magnesium content is substituted for calcium ions in the hydroxyapatite lattice structure. ... | 04/27/2010 |
| 7695740 | Synthetic calcium phosphate comprising silicon and trivalent cation Biomedical materials and, in particular, to substituted calcium phosphate (e.g. apatite and hydroxyapatite) materials for use as synthetic bone. A synthetic calcium phosphate comprising silicon and a trivalent cation having a formula Ca10−yMy... | 04/13/2010 |
| 7611732 | Nutritional supplement for osteoarthritis The present invention relates to a method of treating osteoarthritis by administering a mineral composition in the form of a nutritional supplement, where the mineral composition may contain Smectite, Gypsum, Quartz, Feldspar, Jarosite, Kaolinite and/or Zeolite.... | 11/03/2009 |
| 7597909 | Dietary supplement containing alkaline electrolyte buffers An improved dietary and/or therapeutic supplement composition comprising a quantity of a dietary and/or therapeutic supplement agent having a pH that upon ingestion with food or a beverage would limit the effectiveness of the agent and a sufficient amount of an alka... | 10/06/2009 |
| 7517539 | Method of preparing a poorly crystalline calcium phosphate and methods of its use The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosph... | 04/14/2009 |
| 7419680 | Calcium phosphate-based materials containing zinc, magnesium, fluoride and carbonate Compositions useful in the prevention and treatment of osteoporosis and for bone and fracture repair. Slow-releasing calcium phosphate-based materials are disclosed, incorporating Mg, Zn, F and carbonate, which will promote bone formation and inhibit bone resorption... | 09/02/2008 |
| 7417077 | Composition for an injectable bone mineral substitute material The invention refers to an injectable composition for a bone mineral substitute material, which comprises a dry powder mixed with an aqueous liquid. The powder comprises a first reaction component comprising a calcium sulphate hemihydrate with the capability of bein... | 08/26/2008 |
| 7413753 | Calcium phosphate delivery vehicles for osteoinductive proteins A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an effervescent agent. Methods of making the compositions and methods of using the ... | 08/19/2008 |
| 7399739 | Vertebral augmentation composition and method A flowable vertebral augmentation composition for the treatment and repair of a vertebral body defect, e.g., an osteoporotic condition, contains biocompatible, optionally osteoconductive, support elements that are resistant to deformation or fracture under the norma... | 07/15/2008 |
| 7393405 | Hydraulic cement based on calcium phosphate for surgical use A hydraulic cement is based on calcium phosphate for surgical use, and includes three components. The first component includes α-tricalcium phosphate powder particles. The second, component includes calcium sulphate dehydrate. The third component includes water. Fu... | 07/01/2008 |
| 7387799 | Anti-bacterial, anti-viral, and anti-fungus composition, its preparation and use The present invention relates to an anti-bacterial, anti-viral, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having catalytic... | 06/17/2008 |
| 7387785 | Preparation for treating diseases of bone tissues The present invention refers to an considerably improved medicinal preparation and its synthesizing method, in particular for allowing to affect the osteoreparative process due to stimulation of the prolific and functional activity of osteoblasts without risk of dev... | 06/17/2008 |
| 7387798 | Method and composition for resuscitation The key obstacle for current resuscitation is the acutely limited time window. The major reason for the limited time window is that the brain and spinal cord are extremely vulnerable to hypoxic-ischemic insult. A method and a lymph-like fluid composition for resusci... | 06/17/2008 |
| 7374776 | Bone-filling composition for stimulating bone-forming and bone-consolidation comprising calcium sulfate and viscous biopolymers The present invention relates to a composition for bone-filling, more particularly, to a bone-filling composition for stimulating bone-formation and bone consolidation comprising calcium sulfate and viscous biopolymers. The composition of the present invention can e... | 05/20/2008 |
| 7351433 | Method for producing polymeric sol of calcium phosphate compound and method for coating the same on a metal implant Disclosed is a method for producing a transparent and homogenized polymeric sol of a calcium phosphate compound, containing apatite and having excellent wettability and bioactivity, according to a sol-gel synthesis, and a method for coating the polymeric sol on a me... | 04/01/2008 |
| 7338668 | Drug carrier pellet production process The invention provides a process for the production of drug carrier pellets comprising spray-drying a solution of a physiologically tolerable cellulosic binder containing a physiologically tolerable inert particulate carrier having a particle size D (v, 0.5) of less... | 03/04/2008 |
| 7335664 | Colon cleansing composition and method A composition and method for cleansing a colon prior to endoscopic procedure. More particularly, a combination of bisacodyl, metoclopramide, sodium, and/or a phosphorus containing composition administered in sequential doses for preparing a colon prior to colonoscop... | 02/26/2008 |
| 7323211 | Bone-adherent implant with shock-absorbing property and manufacturing method thereof It is to provide an implant with shock-absorbing property that is able to be strongly secured in a living body as well as a manufacturing method of such implant. The implant comprising: a substrate; a first film on the substrate, which is comprised of a polym... | 01/29/2008 |
| 7320728 | Rod-shaped apatite crystals having a specific length-to-width ratio The rod-shaped apatite crystals of the formula Ca5(PO4)3(OH)xFy have the following features a) the length-to-breadth ratio of the crystals is at least ≧5 and b) x+y=1, where if x or y... | 01/22/2008 |
| 7318841 | Synthesis of calcium phosphates by mechano-chemical process A low crystallinity calcium phosphate powder is prepared by mechanically grinding a calcium phosphate solid under grinding forces local heating sufficient to mechanically alloy the calcium phosphate solid and reduce the crystalline domains of the calcium phosphate s... | 01/15/2008 |
| 7303755 | Pharmaceutical compositions with antibiotic activity The use of certain salts and aminoacids as stabilizer of the antibiotic Fosfomycin Tromethamol and pharmaceutical compositions containing them, is described. ... | 12/04/2007 |
| 7297349 | Copper-containing formulation for plant disease control The present invention relates to a copper-containing formulation for plant disease-control which comprises divalent copper and polyphosphate residues, wherein the amount of the polyphosphate residues per one chemical equivalent of the divalent copper is higher than ... | 11/20/2007 |
| 7279479 | Method for the treatment of heart failure A combination therapy for the treatment of heart failure, particularly acute heart failure, comprises administering a combination of levosimendan or a pharmaceutically acceptable salt thereof and a calcium ion source and/or an intracellular calcium increasing agent ... | 10/09/2007 |
| 7273596 | Method of producing granulated anhydrous dicalcium phosphate A new and useful method of simultaneously producing and granulating anhydrous dicalcium phosphate is provided. Such a method entails the reaction of concentrated phosphoric acid with a powdered material of lime and/or calcium carbonate in substantially equal stoichi... | 09/25/2007 |
| 7255882 | Enkephalinase inhibitor and GABA precursor loading as anti-anxiety compositions Benzodiazepine withdrawal induced anxiety is treated by administration of an enkephalinase inhibitor, and a gamma-aminobutyric acid (“GABA”) precursor, or an endorphin or enkephalin releaser. These components promote restoration of normal neurotransmitter functi... | 08/14/2007 |
| 7252841 | Rapid setting calcium phosphate cements Methods are provided for producing compositions, e.g. pastes or clays, which rapidly set into high-strength calcium phosphate products. In the subject methods, dry reactants that include calcium and phosphate sources, as well as a monovalent cation dihydrogen phosph... | 08/07/2007 |
| 7252833 | Calcium phosphate cements comprising an osteoclastogenic agent Methods and compositions are provided for producing flowable compositions, e.g. pastes, that set into calcium phosphate products that include an osteoclastogenic agent. In the subject methods, dry reactants that include a calcium source and a phosphate source are co... | 08/07/2007 |
| 7241439 | Biopesticide compositions The present invention relates to compositions suitable for use against one or more pathogens comprising at least one antagonistic micro-organism and at least one stimulating agent, which may be selected from the group consisting of one or more uronic acids, mannans,... | 07/10/2007 |
| 7235556 | Methods of treating dry eye disorders Fused pyridazine derivatives are useful for treating dry eye disorders and other disorders requiring the wetting of the eye. ... | 06/26/2007 |
| 7226620 | Directly compressible tricalcium phosphate A compressible tricalcium phosphate agglomerate comprises tricalcium phosphate particles, each having an outer surface, and a binder comprising a polyvinylpyrollidone, carrageenan, or a guar gum, supported on at least a portion of the outer surface of at least a por... | 06/05/2007 |
| 7223420 | Powder mixture for resorbable calcium phosphate biocements The present invention relates to a powder mixture for resorbable calcium phosphate biocements, which mixture consists of 40–99% by volume of powder having a particle size of 0.1–10 μm, 1–20% by volume of powder having a particle size of 10–43 μm and 0–59... | 05/29/2007 |
