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| Number | Title | Issue Date |
| 8163308 | Homeopathy-based formulation A formulation comprising a potentized mixture of triturated Lichen planus tissue with histamine in the ratio of about 1:2 to about 2:1 in a vehicle, where the ratio of the mixture to the vehicle, can be varied from 1:99 to 50:50. ... | 04/24/2012 |
| 7438922 | Human prostate cell lines in cancer treatment Combinations of cell lines are provided for allogeneic immunotherapy agents in the treatment of cancer. Cancer vaccines generally have been limited to the use of cells that contain at least some tumor specific antigens (“TSAs”) and/or tumor associated antigens (... | 10/21/2008 |
| 7332157 | Methods for human allografting A method of preparing a human recipient for a graft from a human which includes: inducing mixed chimerism in the recipient (e.g., by administering to the recipient irradiation or chemotherapy), administering thymic irradiation, administering an antibody that deplete... | 02/19/2008 |
| 7316927 | Culture of goblet cells The invention encompasses isolation, culture and characterization of goblet cells in vitro from mammalian conjuctiva. Goblet cells can be cultured from conjunctiva of such mammals as, e.g., humans, rats, mice, rabbits and the like. In another aspect of the invention... | 01/08/2008 |
| 7285638 | Method of obtaining biologically active collagen from skins of the salmonidae fish The method of obtaining collagen as above, is characterized by this, that the process of cleaning the skins is done manually using tools made of natural materials such as glass and wood to remove from the skins scales, skills and meat tissue so prepared raw material... | 10/23/2007 |
| 7262174 | Treatment for wounds It has been discovered that increasing telomerase activity in cells surrounding a wound has a variety of effects that enhance wound healing. Replication capacity is enhanced, and the mobility of the epithelial cells can be increased by 3-fold or more. Some aspects o... | 08/28/2007 |
| 7232579 | Composition containing a marine-derived inorganic substance and chitin/chitosan, and method of producing the composition A composition contains an inorganic substance obtained as a residue after incinerating skins of marine organisms, and chitin/chitosan. The composition is obtained by incinerating the skins of the marine organisms at a temperature within a range between 600° C. and ... | 06/19/2007 |
| 7163702 | Process for isolating sea cucumber saponin Frondoside A, and immunomodulatory methods of use This present invention discloses use of a chloroform/solvent mixture extraction at different solvent-to-feed ratios, followed by evaporation and extraction with ethyl acetate/water; followed by chromatography of the water phase in Teflon or other non-polar resin and... | 01/16/2007 |
| 7153518 | Processed soft tissue for topical or internal application Disclosed herein are novel injectable, biocompatible compositions, preferably, comprising a combination of particulate, processed tissue and a carrier. Specifically disclosed are compositions comprising acellular, pulverized dermis combined with at least one glycosa... | 12/26/2006 |
| 7144588 | Method of preventing surgical adhesions The present invention relates to a method and composition for preventing surgical adhesions during surgery. Tissue surfaces and/or surgical articles involved in the surgery are separated by a biomaterial provided in the form of a non-crosslinked, decellularized and ... | 12/05/2006 |
| 7087089 | Graft prosthesis devices containing renal capsule collagen The invention provides tissue graft compositions comprising collagen-based extracellular matrices derived from renal capsules of warm-blooded vertebrates. The invention further provides a process of harvesting and purifying a renal capsule to provide an extracellula... | 08/08/2006 |
| 7052690 | Culture of goblet cells The invention encompasses isolation, culture and characterization of goblet cells in vitro form mammalian conjuctiva. Goblet cells can be cultured from conjunctiva of such mammals as, e.g., humans, rats, mice, rabbits and the like. In another aspect of the invention... | 05/30/2006 |
| 6969532 | Compounds inhibiting COX-2 and iNOS promoter activities A new chemical compound for treating human inflammatory diseases, tissue damage, stroke, septic shock and cancer. This chemical compound is produced from a process including the following steps: (a) washing human foreskin fibroblasts with a fresh DMEM medium then in... | 11/29/2005 |
| 6933103 | Biocompatible tissue for therapeutic use and method of making same A biocompatible graft material and a method for making the same are disclosed. The method of making the graft material involves freezing and subsequently thawing a donated tissue sample in a bleach solution. The tissue is then washed in a detergent solution, treated... | 08/23/2005 |
| 6933326 | Particulate acellular tissue matrix A method of processing an acellular tissue matrix to give a particulate acellular tissue matrix includes: cutting sheets of dry acellular tissue matrix into strips; cryofracturing the dry acellular tissue matrix strips at cryogenic temperatures; separating the resul... | 08/23/2005 |
| 6918396 | Method for vocal cord reconstruction A method for surgical repair of damaged or diseased head and neck tissues is described. In one aspect of the invention tissue graft constructs comprising vertebrate submucosa or vertebrate basement membrane materials are used to repair and promote growth of endogeno... | 07/19/2005 |
| 6797260 | Bleeding control and healing aid compositions and methods of use A composition is disclosed which has been shown to stop or control bleeding and seal open small blood vessels while accelerating the healing process of abraded oral “gum” and other “skin” (epithelial) tissues. The composition is preferably in the form of a p... | 09/28/2004 |
| 6660280 | Collagen product containing collagen of marine origin with a low odor and preferably with improved mechanical properties, and its use in the form of cosmetic or pharmaceutical compositions or products The invention relates to a collagen product containing collagen of marine origin with a low odor. The collagen product includes one or more collagens or derivatives thereof, including hydrolyzates, with a low odor, at least part of the collagen or the der... | 12/09/2003 |
| 6652840 | Bleeding control and healing aid compositions and methods of use A composition is disclosed which has been shown to stop or control bleeding and seal open small blood vessels while accelerating the healing process of abraded oral "gum" and other "skin" (epithelial) tissues. The composition is preferably in the form of ... | 11/25/2003 |
| 6645942 | Somatic cell gene therapy The present invention is a somatic cell gene therapy method that is especially useful for the treatment of certain diseases that are caused by gene defects. According to the invention, fibroblast cells are transduced so that they express a "replacement" g... | 11/11/2003 |
| 6627229 | Antiviral agent and method of producing the same An antiviral agent of an antiviral ability against various viruses and a method of producing the same are provided. A heat treatment is applied to a calcium-containing substance represented by calcium carbonate-containing substances originating from the a... | 09/30/2003 |
| 6623733 | Methods for treatment of vascular disease and device for preparation of an autologous composition for treating vascular disease A method for making a composition for administration to a patient, where the method includes: harvesting tissue including cells from a patient, lysing the cells to form a lysate, filtering the lysate to yield a filtrate, and collecting the filtrate as a c... | 09/23/2003 |
| 6585969 | Non-viable keratinocyte cell composition or lysate for promoting wound healing Cultures of keratinocyte cells are provided which are free from nonautologous fibroblasts and organ extracts, and which have a high speed of cell amplification for a minimum seeding density. The cultures can be cryopreserved in a buffered isotonic medium ... | 07/01/2003 |
| 6579538 | Tissue regenerative compositions for cardiac applications, method of making, and method of use thereof A matrix, including epithelial basement membrane, for inducing repair of mammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate.... | 06/17/2003 |
| 6558949 | Media for culturing human cells comprising human serum and method for culturing human cells using the same This invention relates to media for culturing human cells that the proliferation speed of human cells is increased and the cell expression type is stably manifested, and to a method for culturing human cells using the same. This invention is characterized... | 05/06/2003 |
| 6541519 | Methods and compositions for treating lipoxygenase-mediated disease states Methods and compositions are disclosed for prevention and/or treatment of diseases in which 5- and 12-lipoxygenase activity contributes to the pathological condition, by administration of 12-methyletradecanoic acids alone and in conjunction with other the... | 04/01/2003 |
| 6541036 | Treatment of tumors with oligonucleotides directed to insulin-like growth factor-I receptors (IGF-IR) A method of inducing resistance to or regression of tumor growth comprising placing tumor cells in culture in vitro or ex vivo supplemented with a pro-apoptotic agent for a period of time, transferring the tumor cells into a diffusion chamber, thereby pro... | 04/01/2003 |
| 6537567 | Tissue-engineered tubular construct having circumferentially oriented smooth muscle cells Improved methods for the production of tissue-engineered constructs, including muscular tissue constructs such as vascular constructs, are disclosed. The methods include the use of improved substrates for cell growth, improved cell culture media for cell ... | 03/25/2003 |
| 6514514 | Device and method for regeneration and repair of cartilage lesions Disclosed is a cartilage repair product that induces both cell ingrowth into a bioresorbable material and cell differentiation into cartilage tissue. Such a product is useful for regenerating and/or repairing both vascular and avascular cartilage lesions,... | 02/04/2003 |
| 6506415 | Method of inducing resistance to tumor growth A method of inducing resistance to tumor growth comprising placing tumor cells in culture in vitro supplemented with a pro-apoptotic agent for a period of time, transferring the tumor cells into a diffusion chamber, thereby producing a cell-containing cha... | 01/14/2003 |
| 6506414 | Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof This invention relates to a process by which organic solvent-containing solutions are used in lieu of pure water for the preparation of cartilage extracts and fractions thereof. Different organic solvents have been tested for the preparation of extracts c... | 01/14/2003 |
| 6428950 | Assay to identify compounds that alter apolipoprotein E expression The present invention provides a method of assaying for and arresting, preventing and/or reversing the impairment of central and peripheral nervous system function comprising reducing ଲ-amyloid plaque burden by the administration of compounds that r... | 08/06/2002 |
| 6429193 | CELL CHEMOTACTIC FACTOR (CCTF) ORIGINATING IN MAMMALIAN TOOTH PRICEMENT OR CEMENT, METHOD FOR PURIFYING THE SAME, AND NOVEL CONNECTIVE TISSUE ADHESION PROMOTERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT A precementum- and/or cementum-derived chemotactic factor (CCTF) of a tooth of a Mammalian is characterized by a molecular weight measured by SDS-PAGE of 67000&#b1;1000. A process for purifying a precementum- and/or cementum-derived gingival fibroblast ch... | 08/06/2002 |
| 6368636 | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation A method of reducing an immune response to a transplant in a recipient by treating said recipient with an amount of mesenchymal stem cells effective to reduce or inhibit host rejection of the transplant. The mesenchymal stem cells can be administered befo... | 04/09/2002 |
| 6352714 | Method of producing a metal nutrient for an animal feed A leather hydrolysate metal proteinate to be used as a metal nutrient for an animal feed. Chrome tanned leather scrap and shavings are heated in an aqueous solution with an alkali material to produce a water soluble, low molecular weight protein hydrolysa... | 03/05/2002 |
| 6284284 | Compositions and methods for production and use of an injectable naturally secreted extracellular matrix The present invention discloses compositions containing natural human extracellular matrices and methods for the use thereof. More particularly, the present invention provides compositions and methods for the repair of skin defects using natural human ext... | 09/04/2001 |
| 6272235 | Method and apparatus for creating a virtual microscope slide A method and apparatus are disclosed for constructing a virtual microscope slide comprised of digitally scanned images from a microscope specimen. The digitally scanned images are arranged in a tiled format convenient for viewing without a microscope, and... | 08/07/2001 |
| 6231879 | Biocompatible devices with foam scaffolds This invention is directed to methods of manufacturing implantable biocompatible cell encapsulation devices, wherein the cell encapsulation devices have a jacket made of a permeable, biocompatible material that is loaded with a core made of a reticulate f... | 05/15/2001 |
| 6207159 | Methods for the diagnosis and treatment of insulin-dependent diabetes mellitus Methods for detecting the status of an insulin-dependent diabetes mellitus (IDDM)-associated autoimmune response in a mammal are provided. Specifically, the ratio of the frequency of T helper 1 cells to T helper 2 cells specific for a pancreatic ଲ-c... | 03/27/2001 |
| 6165515 | Method for treatment of osteoporosis A therapeutic agent for osteoporosis brought about by a decrease in estrogen comprises an extract from inflammatory rabbit skin inoculated with vaccinia virus as an effective component. In ovariectomized rats, a model animal for osteoporosis brought about... | 12/26/2000 |
