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| Number | Title | Issue Date |
| 8168230 | Platelet gel comprising platelet-rich plasma, platelet activator and polymer A semi-synthetic platelet gel comprising a platelet-rich plasma, at least one platelet activator, and a biocompatible polymer selected from the group comprising carbomers, polyalkylene glycols, poloxamers, polyesters, polyethers, polyanhydrides, polyacrylates, polyv... | 05/01/2012 |
| 8124130 | Formulations and methods for recovery from dental surgery Methods and formulations for the improvement of recovery following bone-impacting injury or surgery. The formulations of the present invention preferably include platelet-rich plasma with a pharmaceutical agent. The pharmaceutical agent may be a glucocorticoid hormo... | 02/28/2012 |
| 7341873 | Method for determination of platelets quality There is provided a method for assessing the quality of platelet concentrates for determining their suitability for transfusion. More specifically dynamic light scattering measurements of the samples containing platelets are obtained and parameters, such as hydrodyn... | 03/11/2008 |
| 7314755 | Preservation of eukaryotic cells using reversible pore formation A method is disclosed for reliably stabilizing eukaryotic cells that express the P2X7 receptor channel, particularly mammalian and other vertebrate cells, including human cells, for example mammalian macrophages, or hematopoietic stem cells, in order to i... | 01/01/2008 |
| 7253142 | Protein solution preparation and method of stabilizing the same The present invention provides stable protein solution formulations filled in a container made from a hydrophobic resin at least for the part in direct contact with said formulation. ... | 08/07/2007 |
| 7244552 | Artificial dermis and production method therefor Artificial dermis (1) obtained from plasma with platelets (2) and human fibroblasts. The plasma with platelets (2) is obtained from the fractionating of total blood (4) from the patient (8) by light centrifugation, and the human fi... | 07/17/2007 |
| 7220747 | Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer This invention provides methods for treating cellular blood components and other cells containing mitochondria to improve vital qualities of the cells by contacting the cells with a mitochondrial enhancer to the cells. Mitochondrial enhancers prevent damage to and r... | 05/22/2007 |
| 7202020 | Compositions, methods and apparatuses for preserving platelets A platelet composition suitable for direct transfusion into a patient is provided. The platelet composition includes a preservation medium comprising plasma and a gel-forming material in a concentration relative to the plasma such that the medium is in a sufficientl... | 04/10/2007 |
| 7169606 | Lyophilization of human platelets A protectant mixture for use in preserving biological materials comprising at least one polyhydroxy compound, and phosphate ions; a preservation medium comprising a biological material, at least one polyhydroxy compound, and phosphate ions; methods of preserving the... | 01/30/2007 |
| 7134437 | Method for utilizing human tissue Percutaneous tissue removal apparatus comprises a flexible drill shaft, a cutting tip mounted on the shaft for placement adjacent a tissue mass for cutting the tissue, means for transmitting motion to the shaft to move the cutting tip against the tissue to cut tissu... | 11/14/2006 |
| 7112342 | Enriched platelet wound healant An improved platelet gel wound healant, and methods of preparation and use thereof for healing wounds are disclosed. The improved wound healant comprises a therapeutically effective amount of activated growth factors and ascorbic acid with optional one or more addit... | 09/26/2006 |
| 7105093 | Processing set and methods for processing and treating a biological fluid Apparatus, systems and methods are disclosed for treating a biological fluid with light. A container of biological fluid is introduced into a fluid treatment chamber where it is contacted with light provided by one or more light sources in proximity to the fluid tre... | 09/12/2006 |
| 7094378 | Method and apparatus for inactivation of biological contaminants using photosensitizers Methods and apparatuses for treating fluids to inactivate microorganisms which may be present therein, said fluid containing one or more components selected from the group consisting of protein, blood and blood constituents are provided. The methods comprise adjusti... | 08/22/2006 |
| 7070557 | Tissue graft material and method of making The present invention relates to a method of making a tissue graft material. The method includes placing body tissue and a blood component in a chamber and extruding the body tissue and blood component from an opening in the chamber to form the tissue graft material... | 07/04/2006 |
| 7049110 | Inactivation of West Nile virus and malaria using photosensitizers Methods and apparatuses are provided for inactivation of microorganisms in fluids or on surfaces. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an effective, non-toxic a... | 05/23/2006 |
| 7011852 | Separation of platelets from whole blood for use as a healant A method is described for separating, retrieving and concentrating platelets from whole blood relying on aggregation of the platelets followed by filtration. This method eliminates the need of a centrifuge for separating said cells from blood. To obtain cellular con... | 03/14/2006 |
| 6998094 | Apparatus for and methods of handling biological sample containers Apparatus for handling biological sample containers comprises a conveyor assembly for conveying containers and a lid handling assembly operable to remove lids from and replace lids onto containers while the containers are in motion on the conveyor assembly. The lid ... | 02/14/2006 |
| 6960464 | Methods for lyophilizing competent cells This invention relates to a method for producing cells which are competent for transformation and which may be stably stored for extended periods of time at various temperatures. The method involves growing cells in a growth conducive medium, rendering said cells co... | 11/01/2005 |
| 6955682 | Wound closure system and methods A wound closure system and methods utilizes a patient's own blood. The system preferably includes a chamber with a needle and a plunger for transferring and storing blood prior to surgery and the use of reversible anticoagulants. The chamber is pre-loaded with a rev... | 10/18/2005 |
| 6942880 | Autologous platelet gel having beneficial geometric shapes and methods of making the same The present invention relates to the production of platelet gels formed into beneficial geometric shapes. Specifically the present invention provides a simpler way to introduce platelet gel for specific uses, such as into the cavity of a gum left after a tooth extra... | 09/13/2005 |
| 6899813 | Method for the production of a blood component composition A system for the production of a blood component composition is provided. The system includes a centrifuge having a blood reservoir for receiving and separating a blood sample into multiple components; a dispenser disposed outside of the centrifuge having a first co... | 05/31/2005 |
| 6863829 | Anti-bacteria agent made from shell, and methods for purifying and desalinating water and for washing agricultural products with use thereof For providing an anti-bacteria which is made from a natural material, therefore harmless if it is absorbed in the human body, can be produced in mass production with low cost, and shows a high anti-bacteria effect, the anti-bacteria agent is obtained by heating a sh... | 03/08/2005 |
| 6855489 | Systems and methods for removing viral agents from blood Systems and methods treat plasma carrying contaminants and cellular matter that are capable of entraining contaminants. The systems and methods separate cellular matter from the plasma by filtration, thereby removing contaminants entrained within the cellular matter... | 02/15/2005 |
| 6841170 | Process for preparing an autologous platelet gel and membrane thereof A process is disclosed for preparing an autologous platelet gel and membranes thereof comprising mixing a platelet concentrate with a calcium salt and batroxobin. This process encompassing the use of batroxobin as the gel activator allows to overcome the prior art p... | 01/11/2005 |
| 6830762 | Autologous fibrin sealant and method for making the same The present relates to an autologous bioadhesive sealant composition or fibrin glue prepared by a two-phase method, wherein all of the blood components for the bioadhesive sealant are derived from a patient to whom the bioadhesive sealant will be applied. A platelet... | 12/14/2004 |
| 6828090 | Compositions, methods and apparatuses for preserving platelets A platelet composition suitable for direct transfusion into a patient is provided. The platelet composition includes a preservation medium comprising plasma and a gel-forming material in a concentration relative to the plasma such that the medium is in a sufficientl... | 12/07/2004 |
| 6723497 | Therapeutic platelets and methods A dehydrated composition is provided that includes freeze-dried platelets. The platelets are loaded with trehalose which preserves biological properties during freeze-drying and rehydration. The trehalose loading is conducted at a temperature of from greater than ab... | 04/20/2004 |
| 6716187 | Platelet concentration syringe kit A single-use system for separating blood and producing platelet concentrates includes an elongated container for receiving blood from a patient. The container has a movable plunger mounted within the blood container for expressing blood fractions separated during ce... | 04/06/2004 |
| 6695805 | Systems and methods for removing free and entrained contaminants in plasma Systems and methods treat plasma carrying contaminants and leukocytes that are capable of entraining contaminants. The systems and methods separate leukocytes from the plasma by filtration, thereby removing contaminants entrained within leukocytes. The sy... | 02/24/2004 |
| 6653063 | Hematology composition using preserved white blood cells in combination with source particles to simulate native white blood cells and method of making same A hematology control composition and method of making the composition is provided. The control employs a plurality of components including a synthetic plasma component, a red blood cell component, a platelet component and a leukocyte component. The leukoc... | 11/25/2003 |
| 6649072 | Method for producing autologous platelet-rich plasma A novel method for producing an autologous platelet rich blood composition is described. The resulting blood composition is useful in procedures for enhancing bone fusion, hemostasis, and repairing soft tissue in animals.... | 11/18/2003 |
| 6610291 | Ready-to-use ristocetin cofactor test reagent possessing long-term stability The present invention relates to a ready-to-use ristocetin cofactor test reagent possessing long-term stability for use in coagulation tests.... | 08/26/2003 |
| 6599881 | Antithrombotic materials and methods Antithrombotic materials and methods are provided for the treatment of thrombotic disorders, in which therapeutically effective amounts of BPI protein products are administered.... | 07/29/2003 |
| 6599724 | Stable factor VIII compositions The present invention relates to a pharmaceutical composition comprising Factor VIII and the divalent metal ions Zn2+ and Cu2+, optionally in the presence of Ca2+ ions and/or Mn2+ ions, wherein said Factor VIII ... | 07/29/2003 |
| 6596180 | System and method for the production of autologous platelet gel A centrifuge system for the formation of an autologous platelet gel wherein all of the blood components for the gel are derived from a patient to whom the gel is to be applied. First a platelet rich plasma and a platelet poor plasma are formed by centrifu... | 07/22/2003 |
| 6589759 | Compositions and methods for producing platelets and/or proplatelets from megakaryocytes The present invention describes novel compositions and methods to enhance the in vitro and in vivo production of platelets and/or proplatelets from megakaryocytes. The present invention describes compositions comprising megakaryocytes, nitric oxide donors... | 07/08/2003 |
| 6444228 | Autologous fibrin sealant and method for making the same In general, the present invention relates to a two-phase method for forming an autologous bioadhesive sealant composition or fibrin glue wherein all of the blood components for the bioadhesive sealant are derived from a patient to whom the bioadhesive sea... | 09/03/2002 |
| 6362003 | Hematological reference control composition containing leukocyte analogs, methods of making, and uses thereof A method of quality control to diagnose the cause of a malfunction of an instrument. The method uses measurements of the physical property of a sample to diagnose the cause of a malfunction of an instrument. The spatial position of a control product sampl... | 03/26/2002 |
| 6303152 | Process for the production of substances that have been bactericidally treated and/or exhibit immune-modulatory activity, and the use thereof A process is disclosed for the production of immune-genetically active suspensions of which the initial substances are fluids or tissues from the human or animal body. Autohemotherapy, immune-stimulatory and/or immune-suppressive effects are employed. The... | 10/16/2001 |
| 6284871 | Factor IX binding peptides, derived from factor VIII and their use as inhibitors of blood coagulation The present invention relates to biologically active peptides which specifically inhibit the Factor IX-dependent pathway of blood coagulation. These peptides are based on a specific motif which represents a sequence of Factor VIII (amino acid 1811-1818) i... | 09/04/2001 |
