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A method of swing on a swing is disclosed, in which a user positioned on a standard swing suspended by two chains from a substantially horizontal tree branch induces side to side motion by pulling alternately on one chain and then the other.
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| Number | Title | Issue Date |
| 7670627 | pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients The present invention relates to a novel pH triggered, targeted controlled release system. The controlled delivery system of the present invention is substantially a free-flowing powder formed of solid hydrophobic nano-spheres comprising pharmaceutical active ingred... | 03/02/2010 |
| 7537787 | Method for modulating glutamate and/or aspartate release in a central nervous system locus Methods and compositions are disclosed for providing prolonged-release of therapeutic agents by way of in situ stereotaxic implantation in specific loci, including pathways, to treat know disorders. One or more microstructures comprising therapeutic agents and pharm... | 05/26/2009 |
| 7442385 | Chemoembolisation A composition for chemoembolotherapy of solid tumours comprises particles of a water-insoluble water-swellable synthetic anionic polymer and, absorbed therein an anthracycline. Suitably the polymer is a poly(vinyl alcohol) based polymer and the drug is doxorubicin. | 10/28/2008 |
| 7442388 | Phospholipid-based powders for drug delivery Phospholipid based powders for drug delivery applications are disclosed. The powders comprise a polyvalent cation in an amount effective to increase the gel-to-liquid crystal transition temperature of the particle compared to particles without the polyvalent cation.... | 10/28/2008 |
| 7432294 | Pharmaceutical formulations Improved pharmaceutical compositions are provided comprising one or more solubilized HIV protease inhibiting compounds having improved solubility properties in a medium and/or long chain fatty acid, or mixtures thereof, a pharmaceutically acceptable alcohol, and wat... | 10/07/2008 |
| 7407667 | Pesticidal preparations comprising copolymers The present invention relates to aqueous concentrates and solid formulations of pesticide preparations comprising copolymers which may be obtained by copolymerization of a) glycerol, b) at least one dicarboxylic acid, and c) at least one monocarboxylic acid of the f... | 08/05/2008 |
| 7404966 | Transfer-resistant makeup removing compositions The invention relates to a cleansing composition suitable for topical application to human skin, more particularly to an oil-based cleansing composition containing a silicone elastomer gelling agent for removal of make-up from the skin. ... | 07/29/2008 |
| 7399488 | Abuse-deterrent pharmaceutical compositions of opiods and other drugs An abuse-deterrent pharmaceutical composition has been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opiods. In the preferred embodiment, a drug is modified to increase its lipophilicity. In preferred embodiments th... | 07/15/2008 |
| 7323039 | Method for preparing microsphere It is to provide an improved method for preparation of microsphere from an emulsion wherein an organic phase containing an organic solvent having a boiling point lower than that of water and a hardly-water-soluble polymer is emulsified in an aqueous phase by an in-w... | 01/29/2008 |
| 7300919 | Pulmonary delivery of active fragments of parathyroid hormone Systemic delivery of parathyroid hormone to a mammalian host is accomplished by inhalation through the mouth of a dispersion of an N-terminal fragment of PTH. It has been found that such respiratory delivery of the PTH fragment provides a pulsatile concentration pro... | 11/27/2007 |
| 7291348 | Compositions and methods for biodegradable microspheres as carriers of bioactive substances A cost-effective, scalable technique for producing microspheres loaded with biologically active solid proteins is provided. The microspheres degrade over time and release biologically active VEGF, as demonstrated by the proliferation of HUVECs in vitro compared to n... | 11/06/2007 |
| 7282221 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 10/16/2007 |
| 7279182 | Formulation for spray-drying large porous particles Particles having a tap density less than about 0.4 g/cm3 are formed by spray drying from a colloidal solution including a carboxylic acid or salt thereof, a phospholipid, a divalent salt and a solvent such as an aqueous-organic solvent. The colloidal solution can al... | 10/09/2007 |
| 7276251 | Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid A sustained-release drug composition consisting essentially of microparticles of hyaluronic acid having a high molecular weight or an inorganic salt thereof and a protein or peptide drug encased in said microparticles, wherein the average size of said microparticles... | 10/02/2007 |
| 7252840 | Use of simple amino acids to form porous particles Particles having a tap density of less than 0.4 g/cm3 include a hydrophobic amino acid or salt thereof and a therapeutic, prophylactic or diagnostic agent or any combination thereof. Preferred particles include a phospholipid, have a median geometric diam... | 08/07/2007 |
| 7220731 | Derivatised carbohydrates and their use in solid delivery systems In a composition comprising a therapeutic agent and a compound which is a trisaccharide or higher polysaccharide, that compound has the formula X[—Y-Z]n wherein X and Z are each saccharide molecules in which none, some or all OH groups are derivatised; ... | 05/22/2007 |
| 7220433 | Compositions for parenteral administration and sustained-release of therapeutic agents The present invention is directed to parenterally-administrable microparticles for providing sustained-release of a therapeutic agent in the body, where the microparticles include a polymeric core containing a therapeutically effective amount of a therapeutic agent ... | 05/22/2007 |
| 7220726 | Antifungal pimaricin compositions and therapeutic methods employing same An antifungal composition suitable for parenteral administration to a mammal includes an amount of pimaricin or an antifungal derivative thereof that is effective to inhibit the growth of a fungal infection in a mammal; a pharmaceutically acceptable dipolar aprotic ... | 05/22/2007 |
| 7217427 | Polymersomes and related encapsulating membranes The present invention provides biocompatible vesicles comprising semi-permeable, thin-walled encapsulating membranes which are formed in an aqueous solution, and which comprise one or more synthetic super-amphiphilic molecules. When at least one super-amphiphile mol... | 05/15/2007 |
| 7205343 | Stabilized bioactive preparations and method of use Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that typically comprises a liquid fluorochemical. As density variations between ... | 04/17/2007 |
| 7202326 | Glycolic acid copolymer and method for production thereof A glycolic acid copolymer comprising (a) 80 to less than 95% by mole of glycolic acid monomer units, (b) 5.0 to 20.0% by mole of non-glycolic, hydroxycarboxylic acid monomer units, and (c) 0 to 0.10% by mole of diglycolic acid monomer units, the non-glycolic, hydrox... | 04/10/2007 |
| 7195779 | Storage stable thyroxine active drug formulations and methods for their production This invention provides a storage-stable dosage form of a thyroxine active drug composition which exhibits an improved stability. The formulation contains a thyroxine active drug substance, an alditol, and a saccharide, and, optionally, additional pharmaceutically a... | 03/27/2007 |
| 7195780 | Nanoparticle delivery system The invention relates to the nanotubes of various sizes and composed of a wide variety of materials, or combination of materials. The invention also describes the use of such nanotubes for the delivery of various payloads and, in particular, for the in vivo delivery... | 03/27/2007 |
| 7179490 | Sustained release ionic conjugate A method of spherifying a sustained release ionic conjugate which contains a free carboxyl group-containing biodegradable polymer and a free amino group-containing drug which are ionically bonded to each other. ... | 02/20/2007 |
| 7176171 | Low-viscosity opacifiers without anionic surface-active agents An emulsifier mixture for use in a wax-based opacifier composition is comprised of: (a) an alkyl and/or alkenyl oligoglycoside; (b) a fatty acid partial glyceride and optionally (c) at least one amphoteric surfactant, with the proviso that the ratio by weight of (a)... | 02/13/2007 |
| 7163697 | Biodegradable polymer compositions, compositions and uses related thereto The present application is directed to biodegradable polymers, compositions, including microspheres and nanospheres, formed of such polymers, and methods of using such polymers and compositions. In certain embodiments, the subject polymer compositions include therap... | 01/16/2007 |
| 7160557 | Matrices formed of polymer and hydrophobic compounds for use in drug delivery A lipid or other hydrophobic or amphiphilic compound (collectively referred to herein as “hydrophobic compounds”) is integrated into a polymeric matrix for drug delivery to alter drug release kinetics. In embodiments where the drug is water soluble, the drug is ... | 01/09/2007 |
| 7153838 | Pharmacologically acceptable solvent vehicles An antifungal composition suitable for parenteral administration to a mammal includes an amount of pimaricin or an antifungal derivative thereof that is effective to inhibit the growth of a fungal infection in a mammal; a pharmaceutically acceptable dipolar aprotic ... | 12/26/2006 |
| 7141593 | Pharmaceutical formulations Improved pharmaceutical compositions are provided comprising one or more solubilized HIV protease inhibiting compounds having improved solubility properties in a medium and/or long chain fatty acid, or mixtures thereof, a pharmaceutically acceptable alcohol, and wat... | 11/28/2006 |
| 7108859 | Antineoplastic product, use and formulation thereof An antineoplastic product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antineoplastic product being reached in less than about twelve hours. In one embodiment, there is an immediate rel... | 09/19/2006 |
| 7105174 | Multiple-delayed release anti-neoplastic product, use and formulation thereof An anti-neoplastic product is comprised of at least three delayed release dosages forms, each of which has a different release profile, with the Cmax for the anti-neoplastic product being reached in less than about twelve hours after initial release of an... | 09/12/2006 |
| 7101568 | Methods and compositions for treating solid tumors A biodegradable polymer composition comprising: (a) a poly(phosphoester) biodegradable polymer and (b) at least one antineoplastic agent in an amount effective to inhibit the growth of a solid tumor, which | 09/05/2006 |
| 7101914 | Isomer enriched conjugated linoleic acid compositions Compositions and methods of using conjugated linoleic acid preparations enriched for the t10,c12 and c9,t11 isomers are disclosed. It is found that preparations of conjugated linoleic acid containing a ratio of t10,c12 to c9,t11 of about greater than 1.2:1 are desir... | 09/05/2006 |
| 7097849 | Injectable aqueous dispersions of propofol Irritation upon injection of a formulation containing propofol is reduced or substantially eliminated by administering a stable, sterile, and antimicrobial aqueous dispersion comprising a water-insoluble microdroplet matrix of mean diameter from about 50 nm to about... | 08/29/2006 |
| 7094420 | Methods of using isomer enriched conjugated linoleic acid compositions Compositions and methods of using conjugated linoleic acid preparations enriched for the t10,c12 and c9,t11 isomers are disclosed. It is found that preparations of conjugated linoleic acid containing a ratio of t10,c12 to c9,t11 of about greater than 1.2:1 are desir... | 08/22/2006 |
| 7090831 | Pharmaceutical aerosol formulation The present invention relates to novel pharmaceutical aerosol formulations comprising: (A) salmeterol xinafoate in the form of particles coated by spray-drying with at least one surfactant in the absence of any other coating excipient, in suspension in (B) a liquefi... | 08/15/2006 |
| 7086466 | Use of substantially hydrated cement particulates in drilling and subterranean applications The present invention relates to substantially hydrated cement particulates. More particularly, the present invention relates to compositions comprising substantially hydrated cement particulates and associated methods of use in drilling and subterranean application... | 08/08/2006 |
| 7078051 | Conjugated linoleic acid alkyl esters in feedstuffs and food A novel method of delivering conjugated linoleic acid to an animal involves compounding feed or food for human consumption with a biologically active amount of conjugated linoleic acid alkyl ester (CLA-ester). The CLA-ester comprises a mixture of c9,t11-octadecanoic... | 07/18/2006 |
| 7074395 | Cosmetic formulations of quaternary ammonium compounds incorporating polyhydric alcohols Cosmetic, dermatological and pharmaceutical compositions containing quaternary ammonium compounds, particularly for hair-treatment, require low setting points, good solubility and dispersibility in aqueous media and a low flash point. It has now been found that such... | 07/11/2006 |
| 7074432 | Method of modifying the release profile of sustained release compositions The present invention relates to a method for the sustained release in vivo of a biologically active agent comprising administering to a subject in need of treatment an effective amount of a sustained release composition comprising a biocompatible polymer having the... | 07/11/2006 |