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Patent No. 5970981

Mouthguard made at least partially from an edible candy

A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.

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Class 424/490 - Coated (e.g., microcapsules)


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which the particle is coated.
No. of patents: 1596
Last issue date: 03/02/2010


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NumberTitleIssue Date
7670626Delivery of a bioactive material
A solid pharmaceutical composition comprising a water-soluble bioactive material and an encapsulating material which is present in the composition in the form of continuous solid phase, and in which solid particles of the bioactive material are dispersed and encapsu...
03/02/2010
7655259Delayed release carnitine
A sustained release, orally administered pharmaceutical composition comprising carnitine and an acceptable pharmaceutical excipient is described for the treatment of carnitine deficiency and other carnitine responsive conditions. The sustained release formulation av...
02/02/2010
7611731Mesostructured silica/block copolymer monoliths as a controlled release device and methods of manufacture
The invention comprises the design, synthesis, and characterization of mesostructured silica/block copolymer composite monoliths as controlled release systems. The controlled release function is based on the formation of mesostructured silica/block copolymer archite...
11/03/2009
7597907Antioxidant polymer nanocarriers for use in preventing oxidative injury
The present invention is a method for encapsulating active protein in a polymeric nanocarrier. The instant method employs homogenization at subzero temperatures so that enzyme activity is retained. Enzymes which can be encapsulated by the present method include, for...
10/06/2009
7575762Composition comprises sustained-release fine particles and manufacturing method thereof
The present invention relates to a composition comprising sustained-release fine particles, characterized in that it contains sustained-release fine particles that can be used in quick-disintegrating tablets in the buccal cavity, one or more fillers selected from th...
08/18/2009
7563456Process for preparation of programmed liberation composition with venlafaxine and the resulting product
Process for the preparation of programmed liberation compositions with venlafaxine and the resulting product, from which the resulting product allows a better absorption of the active principle and a drastic decrease of the adverse effects, due to the preparation me...
07/21/2009
7550158Controlled release by extrusion of solid amorphous dispersions of drugs
Controlled release dosage forms for low solubility drugs are disclosed wherein an amorphous solid dispersion of the drug is coated with a non-dissolving and non-eroding coating that controls the influx of water to the core so as to cause extrusion of a portion of th...
06/23/2009
7550157Method for the preparation of polymeric micelle via phase separation of block copolymer
A method for preparing a biodegradable polymeric micellar composition using liquid polyethylene glycol as a phase separation medium. The present invention also provides an efficient method to effectively incorporate a hydrophobic drug into a polymeric micelle in a p...
06/23/2009
7544373Minocycline oral dosage forms for the treatment of acne
Minocycline oral dosage forms containing a controlled release carrier are useful for the treatment of acne. ...
06/09/2009
7524515Pharmaceutical safety dosage forms
Pharmaceutical safety dosage forms are provided which include a pharmaceutical and an antagonist to the pharmaceutical. The safety dosage forms are such that the antagonist has no significant bioavailability when the pharmaceutical safety dosage form is administered...
04/28/2009
7510729Combination of polyvinyl acetate with water-insoluble, acid-insoluble, or alkali-insoluble polymers used for the production of film coatings with highly controlled release and high stability
The invention relates to the combination of polyvinyl acetate and water-insoluble, acid-insoluble, or alkali-insoluble polymers used for producing film coatings for forms of administration in which agents are released in a controlled manner, and methods for the prod...
03/31/2009
7510730Apparatus and method for preparing microparticles using in-line solvent extraction
Apparatus and method for preparing microparticles using in-line solvent extraction. An emulsion is formed by combining two phases in a static mixer. The emulsion is combined with an extraction liquid in a blending static mixer. The outflow of the blending static mix...
03/31/2009
7498045Biodegradable polymeric nanocapsules and uses thereof
The present invention relates to a biodegradable polymeric nanocapsule composition, adaptable for encapsulation of an agent of therapeutic interest for enhancing the in vivo circulation time of thereof and uses thereof. ...
03/03/2009
7445797Enhanced boron nitride composition and polymer-based compositions made therewith
A boron nitride composition having its surface treated with a coating layer comprising a zirconate coupling agent. The boron nitride composition can be used as fillers in polymeric compounds at levels of up to 90 wt. %, giving thermal conductivity of up to 35 W/mK.
11/04/2008
7442439Microencapsulated heat delivery vehicles
Microencapsulated delivery vehicles comprising an active agent are disclosed. In one embodiment, the microencapsulated delivery vehicles are heat delivery vehicles capable of generating heat upon activation. The microencapsulated heat delivery vehicles may be introd...
10/28/2008
7438929Multi-particulate form of medicament, comprising at least two differently coated forms of pellet
The invention relates to a multiparticulate drug form suitable for uniform release of an active pharmaceutical ingredient in the small intestine and in the large intestine, comprising at least two forms of pellets A and B which comprise an active pharmaceutical ingr...
10/21/2008
7438930Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations
The invention is directed to oral modified/controlled release drug formulations which provide a rapid initial onset of effect and a prolonged duration of effect. Preferably, the peak concentration is lower than that provided by the reference standard for immediate r...
10/21/2008
7435715Microcapsules
Microcapsules for use in liquid detergents having a core and a polyelectrolyte complex shell in the form of a semipermeable membrane capable of withstanding a force before bursting of from about 20 mN to about 20,00 N and having a density of from about 900 Kg/m...
10/14/2008
7431943Controlled release and taste masking oral pharmaceutical compositions
Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrop...
10/07/2008
7431944Delivery of multiple doses of medications
Dosage forms for oral administration of a methylphenidate drug are provided. The dosage forms provide a substantially immediate dose of methylphenidate upon ingestion, followed by one or more additional doses at predetermined times. By providing such a drug release ...
10/07/2008
7429394Ion binding compositions
The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides core-shell compositions and pharmaceutical compositions thereof. Methods of use of the core-shell compositions for therapeutic and/or p...
09/30/2008
7427415Implantation of encapsulated biological materials for treating diseases
The present invention relates to compositions and methods of treating a disease, such as diabetes, by implanting encapsulated biological material into a patient in need of treatment. This invention provides for the placement of biocompatible coating materials around...
09/23/2008
7422757Tabletting process
The invention refers to a process for the preparation of a self-dispersing or self-emulsifying tablet, wherein a heated granulation mixture containing an active lipophilic substance and a surfactant is granulated into granules, said granules are cooled to a semi-sol...
09/09/2008
7422758Sustained release vitamin composition
A therapeutic formulation in the form of a beadlet, suitable for oral administration and adapted to provide immediate and sustained release of therapeutic material. Each beadlet comprises an extruded-spheronized inner core containing at least one medicament e.g. a s...
09/09/2008
7419504Poly(ester amide) block copolymers
Provided herein is a copolymer that includes a soft block (A) that contains poly(ester amide) (PEA) and a hard block (B). The copolymer can be any of AB, ABA or BAB type block copolymers. By varying the relative amount of the PEA block and the hard block, one can ob...
09/02/2008
7408018Elastomeric functional biodegradable copolyester amides and copolyester urethanes
The invention provides elastomeric copolyester amides, elastomeric copolyester urethanes, and methods for making the same. The polymers are based on α-amino acids and possess physical, chemical and biodegradation properties that render them suitable for use in the ...
08/05/2008
7402321Oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles
The invention relates to an oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles and their salts, which comprises the active compound together with tablet disintegrants and is provided with a film coating customary per se for sustained-release c...
07/22/2008
7399487High-concentration aqueous dispersions comprising hydrophilic microfine metal oxide particles and dispersion auxiliaries
Aqueous dispersions comprising microfine metal oxide particles and dispersion auxiliaries, wherein, as dispersion auxiliaries, at least one of the compounds of the general formula (I) in which M is hydrogen, mo...
07/15/2008
7393544Dispersion for pulmonary delivery of a bioactive agent
Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that typically comprises a liquid fluorochemical. As density variations between ...
07/01/2008
7387994Compositions and methods for producing vascular occlusion using a solid-phase platelet binding agent
The present invention relates generally to methods and compositions for targeting and delivering solid-phase platelet-dependent vascular occlusion agents. In particular, particles or coils or stents coated with platelet binding agents are directed to target vasculat...
06/17/2008
7387795Cosmetic compositions organophosphonic acid coated particulates and methods for producing the same
The invention provides cosmetic compositions containing powders that are surface treated with organophosphonic acid compounds, where the surface treated particulates are simultaneously hydrophobic and lipophilic. The invention also provides (a) methods for preparing...
06/17/2008
7384653Oral dosage form comprising a therapeutic agent and an adverse-effect agent
The present invention provides an oral dosage form comprising a first composition and a second composition. The first composition comprises an effective amount of a therapeutic agent and the second composition comprises an effective amount of an adverse-effect agent...
06/10/2008
7378110High pressure spray-dry of bioactive materials
This invention provides compositions and methods providing, e.g., stable powder particles containing bioactive materials. The methods include, e.g., high pressure spraying of the bioactive materials in solution or suspension, with viscosity enhancing agents and/or s...
05/27/2008
7377968Blends of encapsulated biocides
The present invention relates to blends of encapsulated biocides with free biocides. In particular, the present invention relates to blends of encapsulated 4,5-dichloro-2-n-octyl-3(2H)-isothiazolone (“DCOIT”) with free biocides. The invention also relates to mar...
05/27/2008
7374783Powders coated with specific lipoamino acid composition and cosmetics containing the same
There is provided a coated powder having a high skin care effect and a high anti-aging effect. The powder which can be used in cosmetics is coated with a mixture (lipoamino acid composition) comprising N-acyl derivatives (also including the form of a salt) of (1) at...
05/20/2008
7371396Dermatological and cosmetic compositions
The present invention relates to a dermatological and/or cosmetic composition comprising a furfuryl derivative of formula (I), and its use in the treatment of dermatological disorders especially when caused by free radicals. ...
05/13/2008
7368130Microparticles
A method of forming particles comprises accelerating a stream comprising a liquid; and vibrating the stream, to form particles. The particle may have a diameter that is smaller than the diameter of the nozzle used to form the stream, allowing for the formation of mi...
05/06/2008
7368119Compositions and methods for WT1 specific immunotherapy
Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 polynucleotide, a WT1 polypeptide, an antigen-presenting cell presenting a WT1 polypeptide, an antibody that sp...
05/06/2008
7364585Medical devices comprising drug-loaded capsules for localized drug delivery
A medical device comprising a plurality of capsules, and a method of administering therapeutic agent to a patient using the same. The capsules further comprise a therapeutic agent and a multilayer polyelectrolyte shell. The medical device is adapted to apply a press...
04/29/2008
7364562Anti-clotting apparatus and methods for fluid handling system
A method for maintaining clear passageways in an extracorporeal blood flow system. The method comprises intermittently providing one or more anti-clotting agents to a passageway of the extracorporeal blood flow system. Also disclosed is an extracorporeal blood flow ...
04/29/2008
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