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| Number | Title | Issue Date |
| 8105628 | Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects Two (or more), -component, body-implantable, absorbable, biocompatible, putty, and non-putty hemostatic tamponades for use in surgery. Component 1 is a finely powdered bulking material, preferably less than 50 microns, e.g. the calcium, magnesium, aluminum, or bariu... | 01/31/2012 |
| 8101206 | Method of attenuating swelling or inflammation The present invention provides a method of attenuating the formation or reducing the severity of swelling and/or inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion... | 01/24/2012 |
| 8075915 | Composition and method of transmitting ultrasonic and electrical impulses using a physiologically compatible conductive agent The present invention provides a physiologically compatible conductive agent comprising (a) a long chain water-soluble ionic polymeric thickening agent selected from the group consisting of a copolymer of methyl vinyl ether and maleic anhydride, carboxy polymethylen... | 12/13/2011 |
| 8071131 | Mineralizing composite materials for restoring teeth Compositions and methods useful in restorative dentistry are disclosed. Compositions of the present invention include a peptide, and a polymer matrix. The peptide is one capable of reacting with a source of mineralizing ions to initiate deposition of hydroxyapatite ... | 12/06/2011 |
| 8067031 | Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use Crosslinkable compositions are provided that readily crosslink in situ to provide crosslinked biomaterials. The composition contains at least two biocompatible, non-immunogenic components having reactive groups thereon, with the functional groups selected so as to e... | 11/29/2011 |
| 8062667 | Modified release formulations containing drug-ion exchange resin complexes A coated drug-ion exchange resin complex comprising a core composed of a drug complexed with a pharmaceutically acceptable ion-exchange resin is provided. The drug-ion exchange resin complex is in admixture with a release retardant. The coating is a polyvinyl acetat... | 11/22/2011 |
| 8052997 | Anti-bacterial composition and method for producing the same The invention discloses an anti-bacterial composition and method for producing the same. The anti-bacterial composition of the invention includes an organic siloxane material which comprises an amino group, and a plurality of silver atoms. Particularly, the organic ... | 11/08/2011 |
| 8025901 | Bifunctional-modified hydrogels Disclosed are hydrogels wherein a polymer matrix is modified to contain a bifunctional poly(alkylene glycol) molecule covalently bonded to the polymer matrix. The hydrogels can be cross-linked using, for example, glutaraldehyde. The hydrogels may also be crosslinked... | 09/27/2011 |
| 8017150 | Polyethylene oxide-based films and drug delivery systems made therefrom The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains th... | 09/13/2011 |
| 8012505 | Dosage form having a saccharide matrix The present invention provides a non-compressed fast-dispersing solid dosage form suitable for oromucosal administration of a pharmaceutically active substance comprising (a) a first matrix forming agent in the form of maltodextrin... | 09/06/2011 |
| 7989000 | Absorbable putty-like implants and methods for their use for mechanical hemostasis of bone and for the treatment of osseous defects Disclosed are body-implantable, appropriately absorbable, biocompatible, putty-like compositions useful as mechanical hemostatic tamponades for the control of osseous hemorrhage arising from surgical intervention or trauma and for providing an osteoinductive matrix ... | 08/02/2011 |
| 7988999 | Pharmaceutical preparation in the form of a paste comprising an acid-labile active ingredient The present invention relates to the field of pharmaceutical technology and describes a pharmaceutical preparation in the form of a paste comprising an acid-labile active ingredient, in particular an acid-labile proton pump inhibitor. The invention also relates to p... | 08/02/2011 |
| 7968122 | Anti-viral pharmaceutical compositions The present invention provides antiviral compositions that comprise one or more of an ionic multivalent metal component, a cationic polymer, and a cationic surfactant. The present invention also provides methods for making and using such antiviral compositions. ... | 06/28/2011 |
| 7947306 | Modifications of solid 3-sn-phosphoglycerides Methods for hydrolyzing solid ungranulated lysophosphatidylcholine with phospholipase A2 are provided. Also disclosed are methods for making a lipid matrix of lysophosphatidylcholine, monoglyceride and fatty acid, and lipid matrices of particular structur... | 05/24/2011 |
| 7943173 | Pharmaceutical combinations of oxycodone and naloxone Disclosed in certain embodiments is a pharmaceutical composition comprising from 10 to 40 mg of oxycodone or a pharmaceutically acceptable salt thereof and 0.65 to 0.90 mg naloxone or a pharmaceutically acceptable salt thereof. ... | 05/17/2011 |
| 7919117 | Transdermal delivery of (R)-3,3-diphenylpropylamin-monoestern The invention relates to a device for transdermally administering a compound of formula (I), wherein A represents hydrogen or deuterium, R represents a group selected among C1-4alkyl, C3-10cycloalkyl, or phenyl, each of which can be substituted... | 04/05/2011 |
| 7906142 | Agropolymer material for use in water purification and a method of producing the same The present invention relates to novel agropolymers, which comprise a carbohydrate and/or silica matrix substantially devoid of proteins, tannins and polyphenols and which comprise metal binding reactive sites. A method of producing the agropolymers is also disclose... | 03/15/2011 |
| 7897174 | Formulation comprising bioactive agents and method of using same Disclosed are methods of making BMP-2 microparticles and methods of using the microparticles. These microparticles are prepared, for example, by mixing a solution containing BMP-2 with a second solution whose ionic concentration and pH results in the precipitation o... | 03/01/2011 |
| 7897175 | Dosage forms comprising a CETP inhibitors and an HMG-CoA reductase inhibitor A dosage form comprises (1) a solid amorphous dispersion comprising a cholesterol ester transfer protein inhibitor and an acidic concentration-enhancing polymer and (2) an HMG-CoA reductase inhibitor. The solid amorphous dispersion and the HMG-CoA reductase inhibito... | 03/01/2011 |
| 7887842 | Methods of administering a dermatological agent to a subject Methods for administering a dermatological agent to a subject are provided. In the subject methods an effective amount of a topical formulation of the dermatological agent is topically applied to a host. The topically applied formulation of dermatological agent is t... | 02/15/2011 |
| 7875294 | Method of attenuating bruise formation The present invention provides a method of attenuating the formation or reducing the severity of a bruise in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of t... | 01/25/2011 |
| 7867517 | Oral pharmaceutical composition with improved bioavailability The present invention relates to prompt-release oral pharmaceutical compositions containing one or more active principles solubilised, suspended or embedded in a suitably formulated amphiphilic matrix for improving in vitro and in vivo bioavailability of medicaments... | 01/11/2011 |
| 7850992 | Cucurbituril-containing gel and method of preparing the same Provided are a gel including a compound represented by Formula 1 below and a method of preparing the same: wherein n, X, A1, and A2 are as defined in the specification. ... | 12/14/2010 |
| 7829116 | Adhesive-forming composition and blend of adhesives obtained therefrom The present invention relates to novel adhesive-forming compositions of silylated polyurethane prepolymer blended with pre-formed adhesives, and pressure sensitive adhesives containing the same. The silylated polyurethane prepolymer is obtained from the silylation o... | 11/09/2010 |
| 7785627 | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a thiazolidinedione derivative is herein disclosed and described. ... | 08/31/2010 |
| 7771749 | Lignin-based microparticles for the controlled release of agricultural actives A method of producing lignin-based matrix microparticles for the controlled release of an agricultural active includes forming an emulsion of an organic solution in an aqueous solution, wherein the organic solution contains a lignin derivative and an agricultural ac... | 08/10/2010 |
| 7767228 | Pharmaceutical composition for oral application and method for preparing thereof The present invention relates to a pharmaceutical composition for oral application comprising: i) an anthelmintic agent; ii) a first excipient having a porous structure with an inner surface of about 500 to 1500 m2/g and a surface area according to BET of... | 08/03/2010 |
| 7754240 | Topical pharmaceutical formulations and methods of treatment In certain embodiments, the present invention is directed to a pharmaceutical formulation for topical administration on a mammal, comprising a unit dose of a therapeutically effective amount of a therapeutic agent and a pharmaceutically acceptable carrier medium the... | 07/13/2010 |
| 7749538 | Molded object having high pullulan content, process for the producing the same, and use thereof Since conventional high pullulan content shaped products have a low stability to the change of humidity, the object of the present invention is to provide a high pullulan content shaped product having a satisfactory stability to the change of humidity, a process for... | 07/06/2010 |
| 7727550 | Biologically active native biomatrix composition The present disclosure relates to a biologically active biomatrix composition. In one embodiment, the biomatrix composition is derived from human amnions. The biomatrix is termed HuBiogel™. The composition of HuBiogel™ closely mimics naturally occurring basement... | 06/01/2010 |
| 7713551 | Gel stabilized nanoparticulate active agent compositions Disclosed is a solid or semi-solid gelatin nanoparticulate active agent dosage form comprising at least one nanoparticulate active agent and at least one gel forming substance which exhibits gelation sufficient to retain excess water in the solid or semi-solid gelat... | 05/11/2010 |
| 7713942 | Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides The present invention pertains to complexes comprising sterols and saponins. The complexes are capable of binding a genetic determinant including a polynucleotide. The complexes may further comprise a lipophilic moiety, optionally a lipophilic moiety comprising a co... | 05/11/2010 |
| 7662409 | Protein matrix materials, devices and methods of making and using thereof The present invention relates to protein matrix materials and devices and the methods of making and using protein matrix materials and devices. More specifically the present invention relates to protein matrix materials and devices that may be utilized for various m... | 02/16/2010 |
| 7625585 | Method of attenuating neurogenic bruise formation The present invention provides a method of attenuating the formation or reducing the severity of a neurogenic bruise in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the s... | 12/01/2009 |
| 7592021 | Bioadhesive delivery system for transmucosal delivery of beneficial agents Formulations and methods for transmucosal delivery of a beneficial agent are described in which a pH-responsive component and a temperature-responsive component are combined and applied to a mucous membrane. The temperature-responsive component is a component that, ... | 09/22/2009 |
| 7556827 | Implantable active ingredient depot The invention relates to an implantable active ingredient depot for therapeutically active substances. The fields of application are in medicine and the pharmaceutical industry. The implantable active ingredient depot is constituted of a lipid matrix capable of form... | 07/07/2009 |
| 7550154 | Methods of treatment with drug loaded polymeric materials Polymeric microparticles have been developed which encapsulate therapeutic compounds such as drugs, cellular materials or components, and antigens, and can have targeting ligands directly bound to the microparticle surface. Preferred applications include use in tiss... | 06/23/2009 |
| 7544371 | Drug delivery systems Matrix controlled diffusion drug delivery systems based on one or more silicone-containing monomers of the general formula: wherein x, y, m, m′, R, R1, R2, R3, R4, R5... | 06/09/2009 |
| 7534451 | Bone restorative carrier mediums Biocompatible bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities. ... | 05/19/2009 |
| 7482023 | Hygiene tissue with lactic acid producing bacterial strains A hygiene tissue is used for both cleaning and transferring lactic acid producing bacteria to the skin and urogenital area. The hygiene tissue contains, on separate parts of the tissue, cleaning liquid and a bacterial composition. Bacterial viability and transfer ab... | 01/27/2009 |
