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| Number | Title | Issue Date |
| 8409613 | Gastric retained gabapentin dosage form A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ... | 04/02/2013 |
| 8333991 | Gastric retained gabapentin dosage form A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ... | 12/18/2012 |
| 8333992 | Gastric retained gabapentin dosage form A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ... | 12/18/2012 |
| 8329217 | Dual controlled release dosage form A dosage form that provides a controlled release of at least two different active agents is provided. Particular embodiments include a dosage form that provides therapeutically effective levels of a first active agent and a second active agent in a mammal for an ext... | 12/11/2012 |
| 8323691 | Methods and apparatus for determining formulation orientation of multi-layered pharmaceutical dosage forms Rapid and accurate determination of the formulation orientation of multi-layer capsule-shaped tablets with respect to different internal formulation layers proximate to the opposite narrow and rounded ends of the tablets is required. By including an appropriate colo... | 12/04/2012 |
| 8252332 | Gastric retained gabapentin dosage form A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ... | 08/28/2012 |
| 8252331 | Osmotic device containing amantadine and an osmotic salt The osmotic devices of the present invention contain a unitary core comprising a salt of amantadine and an osmotic salt, wherein the two salts have an ion in common. The release rate of the amantadine is modified from a first order release profile to a zero order, p... | 08/28/2012 |
| 8241667 | Dual controlled release osmotic device A pharmaceutical composition and dosage form for the treatment of incontinence with oxybutynin and a second drug is provided. The second drug can be darifenacin or tolterodine. Depending upon the route of administration, the dosage form used, and the second drug use... | 08/14/2012 |
| 8231905 | Gastric retained gabapentin dosage form A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ... | 07/31/2012 |
| 8211467 | Osmotic drug delivery devices containing suspension formulations comprising particles having active agents and nonaqueous single-phase vehicles A nonaqueous, single-phase vehicle that is capable of suspending an active agent. The nonaqueous, single-phase vehicle includes at least one solvent and at least one polymer and is formulated to exhibit phase separation upon contact with an aqueous environment. The ... | 07/03/2012 |
| 8192756 | Gastric retained gabapentin dosage form A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ... | 06/05/2012 |
| 8187633 | Controlled release coated tablets having prolonged gastric retention The present invention relates to a tablet composed of a core and a coating; said core is formed by two or more layers, wherein at least one of them contains an active agent (3). Wherein one of said layers is formulated as a swellable composition (2), t... | 05/29/2012 |
| 8158150 | Two-piece, internal-channel osmotic delivery system flow modulator An osmotic delivery system flow modulator includes an outer shell constructed and arranged for positioning in an opening, an inner core inserted in the outer shell, and a fluid channel having a spiral shape defined between the outer shell and the inner core. The flu... | 04/17/2012 |
| 8084059 | Antidepressant dosage form The invention pertains to a dosage form 10 and to administering an antidepressant medicament 16 for an extended period of time in a rate-known dose. ... | 12/27/2011 |
| 8052996 | Two-piece, internal-channel osmotic delivery system flow modulator An osmotic delivery system flow modulator includes an outer shell constructed and arranged for positioning in an opening, an inner core inserted in the outer shell, and a fluid channel having a spiral shape defined between the outer shell and the inner core. The flu... | 11/08/2011 |
| 7959946 | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a thiazolidinedione derivative is herein disclosed and described. ... | 06/14/2011 |
| 7923027 | Process The present invention relates to a process using ultrasonic cutting for the preparation of an oral delivery device comprising a core which includes a pharmaceutically active agent covered by an outer coating which includes one or more openings communicating from the... | 04/12/2011 |
| 7879355 | Method and system for treatment of eating disorders The invention comprises a gastric device having a pouch formed from a degradable film. Preferably, the pouch contains a gas producing material. The gastric device hydrates within a patient's stomach and the gas producing material expands the device to a greater volu... | 02/01/2011 |
| 7879354 | Rapidly disintegrating gelatinous coated tablets The present invention relates to an improved gelatinous coated dosage form having two end regions coated with gelatinous materials and an exposed circumferential band. Openings are provided in at least the exposed band to reveal the core material. The invention also... | 02/01/2011 |
| 7875293 | Biointerface membranes incorporating bioactive agents A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to... | 01/25/2011 |
| 7807197 | Composite dosage forms having an inlaid portion A dosage form comprises at least one active ingredient, a first portion which comprises an exterior surface and one or more cavities defining at least one interior surface having indentations and an exterior surface, and a second molded portion which is inlaid into ... | 10/05/2010 |
| 7736668 | System for delaying drug delivery up to seven hours A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy. ... | 06/15/2010 |
| 7731989 | Gastric retained gabapentin dosage form A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ... | 06/08/2010 |
| 7713550 | Controlled release sodium valproate formulation Disclosed is a controlled release formulation comprising valproic acid, pharmaceutically acceptable salt thereof, amide thereof, or derivative thereof. ... | 05/11/2010 |
| 7709025 | Enteric coatings for orally ingestible substrates Enteric film coating systems for orally ingestible substrates such as pharmaceutical tablets and dietary supplements are disclosed. In preferred aspects, the enteric film coatings include an ethylcellulose dispersion and a substantially gastro-insoluble pore former ... | 05/04/2010 |
| 7682629 | Floating pharmaceutical composition comprising an active phase and a non-active phase The invention concerns a floating pharmaceutical composition consisting of at least a first phase comprising at least a high dose active principle combined with one or several carriers and at least a second phase comprising at least a gas-generating system. The inve... | 03/23/2010 |
| 7655257 | Sustained delivery of an active agent using an implantable system The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment i... | 02/02/2010 |
| 7514100 | Controlled release hydrocodone formulations A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and controlled release material. ... | 04/07/2009 |
| 7438927 | Methods of treatment using a gastric retained gabapentin dosage A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ... | 10/21/2008 |
| 7419684 | System and method for manufacturing oral osmotic drug delivery devices, and methods of administering same A system and method for manufacturing oral osmotic drug delivery devices including the use of a mathematical model in deriving relationships between parameters used in manufacturing the devices for a desired release rate of the active drug substance contained therei... | 09/02/2008 |
| 7413751 | Methods of treatment using a gastric retained losartan dosage A method of treatment for hypertension and other disease states is described, which comprises the delivery of losartan in a gastric retained dosage form. ... | 08/19/2008 |
| 7387792 | Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration New pharmaceutical compositions in unit dosage form are disclosed for both intraoral and oral administration to a patient, said unit dosage form configured to be placed intraorally of said patient, which comprises: (a) as a first p... | 06/17/2008 |
| 7350479 | System and method for controlling growth of aquatic plants utilizing bio-eroding means implanted in triploid grass carp An “implant and forget” device for interacting with biota after a pre-established time period. Preferably, the biota are fauna and more particularly fish. In select embodiments, the device comprises packaging enclosing apparatus for timing interaction via openin... | 04/01/2008 |
| 7351695 | Topiramate salts and compositions comprising and methods of making and using the same The invention encompasses novel salts of topiramate, and pharmaceutically acceptable polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, or amorphous forms thereof, as well as pharmaceutical compositions and pharmaceutical unit dosage forms containin... | 04/01/2008 |
| 7341986 | Cleaning concentrate consisting of extra virgin olive oil and isopropyl alcohol The invention, a stable composition of matter, has a 2 step method to make (maintain the same equalities in increased batches). Step #1. 0.4167 Extra Virgin Olive Oil First Cold Pressed, which is a high quality olive oil, 0.5833 IPA, Isopropyl Alcohol 70%, shake to ... | 03/11/2008 |
| 7342596 | Method for direct xerography A system for printing is described. The system uses at least one cantilever, and more typically a plurality of cantilever to transfer charge, either to or from a dielectric surface. The resulting charge distribution represents an image. Toner deposited over the diel... | 03/11/2008 |
| 7332183 | Multilayer dosage forms containing NSAIDs and triptans The present invention is directed to multilayer pharmaceutical tablets in which an NSAID and a triptan are present in separate and distinct layers. The layers are in a side-by-side configuration, which allows the dissolution of triptan and NSAID to occur independent... | 02/19/2008 |
| 7332525 | Method of treatment of prostate cancer and composition for treatment thereof A method and composition for the treatment of prostate cancer comprises an effective amount of a nonsteroidal antiandrogen and an effective amount of a selective estrogen receptor modulator. The composition has fewer side effects such as breast tenderness and gyneco... | 02/19/2008 |
| 7329418 | Pharmaceutical tablets having height greater than width An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die... | 02/12/2008 |
| 7329412 | Antimicrobial medical devices containing chlorhexidine free base and salt The present disclosure invention relates to medical devices treated with a solution comprising one or more solvents and a combination of chlorhexidine free base and a water-soluble chlorhexidine salt in a weight/weight ratio of between about 1:1 to about 1:5, prefer... | 02/12/2008 |
