In 1608, Dutch eyeglass maker Hans Lipperhey filed the first patent for a working telescope. The patent was denied.
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| Number | Title | Issue Date |
| 7521024 | Magnetic bead-based migration apparatus This invention relates to a method to make biopolymers such as proteins or nucleic acids migrate by applying a spatially distributed magnetic field to a solution containing biopolymers marked with magnetic beads. In this case, marking the biopolymers to be fractiona... | 04/21/2009 |
| 7402292 | Device and methods of ammonia generation for NOx abatement One embodiment of a method of operating a NOx abatement system comprises: introducing an exhaust stream to an ammonia generator in a normal flow direction, adsorbing NOx from the exhaust stream in the ammonia generator, diverting the exhaust stream around the ammoni... | 07/22/2008 |
| 7112449 | Combinatorial chemical synthesis Combinatorial synthesis methods obtain a plurality of compositions having materially different characteristics using an apparatus having a plurality of collectors. A first quantity of fluid reactants are reacted to form a first quantity of product composition. Follo... | 09/26/2006 |
| 7067101 | Water wall boiler for air and oxygen fired Claus sulfur recovery units The thermal combustion step of the modified Claus process is carried out in a water-wall boiler instead of a refractory-lined reaction furnace. The water-wall boiler replaces the conventional refractory-lined furnace and waste heat boiler when air, oxygen, or oxygen... | 06/27/2006 |
| 7001503 | Method and apparatus for stripping sulfur-containing compounds from hydrocarbon feed stock in hydrorefining of petroleum distillates A unit for hydrorefining of hydrocarbon crude oil comprising sulfur-containing compounds comprises first catalyst layer 33 and second catalyst layer 38, top space 34 for separating vapor component and liquid component, bottom space 36, an... | 02/21/2006 |
| 6680407 | Installation and process for the preparation of urea The invention relates to an installation for the preparation of urea from ammonia and carbon dioxide, the installation comprising two reactor sections in a vertically placed combined reactor and a high-pressure condenser section. The installation may comp... | 01/20/2004 |
| 6600031 | Methods of making nucleic acid or oligonucleotide arrays A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techni... | 07/29/2003 |
| 6419883 | Chemical synthesis using solvent microdroplets The present invention relates to microdroplets of a solution comprising a solvent having a boiling point of 150° C. or above, a surface tension of 30 dynes/cm or above, and a viscosity of 0.015 g/(cm)(sec). Such microdroplets are useful for the synthesis... | 07/16/2002 |
| 6375903 | Method and apparatus for synthesis of arrays of DNA probes The synthesis of arrays of DNA probes sequences, polypeptides, and the like is carried out using a patterning process on an active surface of a substrate. An image is projected onto the active surface of the substrate utilizing an image former that includ... | 04/23/2002 |
| 6261771 | Method and apparatus for detection of multiple nucleic acid sequences and multiple antigens A method and apparatus for detection of multiple target nucleic acids and/or antigens such as hormones, antibodies, or nerve agents in a sample, involves presenting the sample to a plurality of reporter binding sites wherein each reporter binding site com... | 07/17/2001 |
| 6150002 | Creped nonwoven liner with gradient capillary structure A unitary creped nonwoven web has a hydrophobic uncreped side and a creped side. The hydrophobic side includes looped regions. The creped side includes relatively narrow hydrophilic regions. The looped regions and creped regions act in conjunction with ea... | 11/21/2000 |
| 6068978 | Apparatus and method for transfer of a fluid sample Methods, devices, apparatus and kits for amplifying and detecting nucleic acid are provided. The apparatus is a one or two-tier thermal cycling device that operates in conjunction with a reaction/detection unit. A sample is loaded into a reaction chamber ... | 05/30/2000 |
| 5916776 | Amplification method for a polynucleotide The nucleic acid amplification procedures of the present invention provide methods for amplification of a nucleic acid comprised of a first strand, comprising (a) using the first strand to generate copies of a second strand at a first location, (b) moving... | 06/29/1999 |
| 5779977 | Nucleic acid amplification reaction apparatus and method Apparatus and method for performing a nucleic acid amplification reaction and preferably a polymerase chain reaction (PCR) in a reaction mixture in at least one capillary tube. Several different embodiments are disclosed. One embodiment cycles a sample th... | 07/14/1998 |
| 5746982 | Apparatus for automated synthesis of chemical compounds Apparatus for the synthesis of chemical compounds consists of a housing having a top, front, side and rear walls surrounding and enclosing a reaction table. A track on the rear wall of the housing carries a pair of extending arms on each of which is movab... | 05/05/1998 |
| 5728183 | Shift reactor for use with an underoxidized burner A shift reactor is disclosed that is mounted on the exhaust end of an underoxidized burner so that the exhaust product is introduced to a cooler water bath in a compartment of the reactor. The exhaust product is passed through the water bath via submerged... | 03/17/1998 |
| 5720923 | Nucleic acid amplification reaction apparatus Apparatus and method for performing a nucleic acid amplification reaction and preferably a polymerase chain reaction (PCR) in a reaction mixture in at least one capillary tube. Several different embodiments are disclosed. One embodiment cycles a sample th... | 02/24/1998 |
| 5705129 | NOx sensor An NOx sensor has the sensor element made of an oxide, the resistance of which is varied in response to an NOx component in a gas to be measured, and a measuring portion for measuring a resistance variation of the sensor element and for detecting an NOx c... | 01/06/1998 |
| 5677195 | Combinatorial strategies for polymer synthesis A method and device for forming large arrays of polymers on a substrate (401). According to a preferred aspect of the invention, the substrate is contacted by a channel block (407) having channels (409) therein. Selected reagents are delivered through the... | 10/14/1997 |
| 5474960 | Process for reactivating a fluid bed catalyst in a reactor dipley The present invention relates to improvements of fluid bed catalysts. More particularly, the present invention relates to improvements of fluid bed oxidation catalysts useful in the preparation of maleic anhydride from C4 hydrocarbons, includin... | 12/12/1995 |
| 5384261 | Very large scale immobilized polymer synthesis using mechanically directed flow paths A method and device for forming large arrays of polymers on a substrate (401). According to a preferred aspect of the invention, the substrate is contacted by a channel block (407) having channels (409) therein. Selected reagents are flowed through the ch... | 01/24/1995 |
| 5350681 | Enzymatic membrane method for the synthesis and separation of peptides The present invention discloses a method for the enzymatic synthesis of a peptide. A protected peptide having a C-terminal carboxylate group or a protected, N-acyl amino acid having an alpha carboxylate group is reacted with a protected peptide having an ... | 09/27/1994 |
| 5190742 | Device and method for carrying out a plurality of sequential transformations of a substrate A device or kit having inlet means for introducing within the kit a first reagent, includes a substrate and at least a second reagent in the form of microcapsules adapted to release, according to a predetermined release profile, the second reagent after t... | 03/02/1993 |
| 4892142 | Device and method for removing gaseous impurities from a sealed vacuum A container is disposed within a vacuum insulation jacket which surrounds a vessel or pipe which contains or through which flows a hydrogen containing medium. The container holds oxygen under pressure or holds a material which liberates oxygen when expose... | 01/09/1990 |
| 4816513 | Automated polypeptide synthesis process An apparatus is provided for automatically constructing a polypeptide of high purity, up to 50 amino acids in length, using only single couplings. The apparatus includes an activation system for receiving protected amino acids, one kind at a time, having ... | 03/28/1989 |
| 4716023 | Composite partial oxidizer and reformer A partial oxidizer and reformer comprising a tubular member having a wick adjacent its inner wall and a catalyzed metallic spiral adjacent the wick and further comprising an annular member connected to and surrounding the tubular member and in which is di... | 12/29/1987 |
| 4666676 | Radioactive waste processing apparatus Apparatus for use in processing radioactive waste materials for shipment and storage in solid form in a container is disclosed. The container includes a top, and an opening in the top which is smaller than the outer circumference of the container. The app... | 05/19/1987 |
| 4575453 | Modified Claus furnace Modified Claus furnace containing, in addition to primary reaction chamber, a secondary chamber in heat exchange with said primary reaction chamber wherein H2 S is cracked to supply hydrogen needed downstream in a clean-up system. This eliminat... | 03/11/1986 |
| 4476918 | Method and apparatus for a temperature-shifted chemical heat pipe A method and apparatus are provided in a chemical heat pipe for shifting the reaction equilibrium in order to operate at a "shifted" temperature without also "shifting" the pressure. A diluent is added to the heat pipe in a constant-pressure manner near a... | 10/16/1984 |
| 4461742 | Pyrolysis of hydrocarbons Process and apparatus for pyrolysis of a heavy hydrocarbon feedstock in which the feedstock is countercurrently contacted with a hot hydrogenating gas stream flowing spirally from the periphery of a substantially circular reactor (1). The hydrocarbon feed... | 07/24/1984 |
| 4304755 | Apparatus for manufacturing vanadium pentoxide Disclosed herein are a process and apparatus for manufacturing vanadium pentoxide in powder form by the thermal decomposition of ammonium metavanadate containing more than 10% NH3 in a single operation.... | 12/08/1981 |
| 4262631 | Thin film deposition apparatus using an RF glow discharge An RF plasma deposition apparatus for depositing a film of material on substrates positioned in a vertical plane and electrically "floating" within the glow discharge. For deposition of silicon nitride films, the apparatus is adapted to introduce silane g... | 04/21/1981 |
| 4014657 | Catalytic-reactor for carrying out conjugate chemical reactions A catalytic reactor for carrying out conjugate chemical reactions, comprising a body with a system of plates arranged in said body parallel to one another and having their edges built into said body, said plates being made of a material selectively permea... | 03/29/1977 |