...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Number | Title | Issue Date |
| 7901635 | Method of multiple reaction in microreactor, and microreactor When fluids A and B are caused to flow together from a fluid introduction portion into a microreactionchannel, they are divided into a plurality of fluid segments A and B in a diametral section of the microreactionchannel at the entrance side, and are mixed with eac... | 03/08/2011 |
| 7892496 | Mechanically-actuated microfluidic pinch valve A microfluidic pinch valve. The valve comprises a microfluidic channel defined in a compliant body; a valve sleeve defined by a section of the microfluidic channel, the valve sleeve having a membrane wall defining part of an outer surface of the body; a compression ... | 02/22/2011 |
| 7887756 | Microfluidic system comprising mechanically-actuated microfluidic pinch valve A microfluidic system. The system comprises: (A) a microfluidics platform comprising: a compliant body having a microfluidic channel defined therein; a valve sleeve defined by a section of the microfluidic channel, the valve sleeve having a membrane wall defining pa... | 02/15/2011 |
| 7842248 | Microfluidic system comprising microfluidic pump, mixer or valve A microfluidic system. The system comprises: (A) a microfluidics platform comprising: a compliant body having a microfluidic channel defined therein; an elongate chamber defined by a section of the microfluidic channel, the chamber having a membrane wall defining pa... | 11/30/2010 |
| 7837947 | Sample mixing on a microfluidic device Mixing structures for use on sample processing devices are disclosed. The mixing structures include one or more mixing chambers in fluid communication with a process chamber, such that changing the rotational speed of the sample processing device forces sample mater... | 11/23/2010 |
| 7837948 | Phase transition type valve and method of manufacturing the same A phase transition type valve is provided. The valve includes a phase transition material filled and hardened in a section of a channel and a tube expanding region which has a larger cross-sectional area than the channel formed at both ends of the section in which t... | 11/23/2010 |
| 7794665 | Fluidic device A fluidic device includes a first material defining a first region, a second material defining a second region that is separated from the first region, and a connector coupled between the first region and the second region. The connector includes a brittle material ... | 09/14/2010 |
| 7767155 | Microreactor apparatus having integral connectors A microreactor apparatus includes; a microreactor body that includes first and second substrates; a microchannel that is formed inside the microreactor body; and integral connectors that are disposed detachably on the microreactor body, and through which supply/disc... | 08/03/2010 |
| 7731910 | Microfluidic mixing assembly A microfluidic mixing assembly includes at least first and second liquid sources, a microfluidic manifold, a first capillary valve between the first liquid source and the manifold, and a second capillary valve between the second liquid source and the manifold, where... | 06/08/2010 |
| 7695688 | High density plate filler A filling apparatus for filling a microplate. The microplate can comprise a plurality of wells each sized to receive an assay. A substrate can comprise a first surface and an opposing second surface, a first assay input port for receiving the assay disposed on the f... | 04/13/2010 |
| 7678336 | Channel apparatus for focusing a fluid flow Disclosed is a focusing channel device which focuses fluid containing micro particles so that the micro particles flow in a line. The channel device comprises a nozzle formed by left and right walls each of which comprises an inclination surface. The cross sectional... | 03/16/2010 |
| 7622083 | Multi-capillary electrophoresis cartridge interface mechanism The present invention provides for an interface mechanism in a bio-separation instrument that makes interface connections to a multi-channel cartridge. The interface mechanism precisely positions the cartridge in relation to the support elements in the instrument (e... | 11/24/2009 |
| 7611673 | PMDS microfluidic components and methods of operation of the same Component microfluidic devices which are integrated with polydimethylsiloxane (PDMS) microfluidic chips, include designs for an electrical and optical pressure gauge, valve, electrostatic and magnetic pumps, alternating or mixing pumps, a solenoid, a magnetometer, a... | 11/03/2009 |
| 7575723 | Mass rate attenuator While a large primary stream (24) of analytes flow from a chromatographic column (20) to containers of a receiver (108), small samples of the analytes are diverted for flow to a mass spectrometer (54) for analysis, by use of a transfer mo... | 08/18/2009 |
| 7553455 | Micromanifold assembly A micromanifold for connecting external capillaries to the inlet and/or outlet ports of a microfluidic device can employ a ferrule/capillary assembly that includes: (a) a ferrule comprising an elongated member and having a bore traversing from a proximal end to a di... | 06/30/2009 |
| 7521022 | Receiving device comprising an adjustable covering element The invention relates to a holding device (1) with a holding container (2) for a holding vessel, in particular a blood sample collecting tube, in which the holding container (2) surrounds a holding chamber (7) with a container wall (6 | 04/21/2009 |
| 7501097 | Positioning device for a test element The invention relates an analysis system having a positioning device for positioning a test element and a method for positioning the test element in the analysis system. The positioning device has a support surface for supporting the test element. A first switch com... | 03/10/2009 |
| 7438856 | Microfluidic devices and methods Embodiments of the invention are directed to microfluidic devices. In one embodiment, a microanalysis chip comprises a body having at least one transfer-separation channel with a channel bottom that has a bottom opening. The transfer-separation channel terminates in... | 10/21/2008 |
| 7438858 | Dispensing assembly for liquid droplets A dispensing assembly for liquid droplets that includes a dispenser connected to a liquid carrying pipe which in turn is connected to a source of pressurized liquid. The dispenser has an elongated body member having a main bore connected to the liquid carrying pipe.... | 10/21/2008 |
| 7435381 | Packaging of microfluidic devices A microfluidic device containing liquid reagents having an extended shelf life contains the liquid reagents in micro-reservoirs that limit the escape of moisture to less than 10% over the shelf life of the device. The micro-reservoir preferably is made of polypropyl... | 10/14/2008 |
| 7431884 | Chemical assays An assay device in which to carry out a fluid-phase chemical assay, comprising means for supporting a test substrate, a sample chamber for receiving a fluid sample and at least one fluid control device for controlling the movement of fluid into and/or out of the sam... | 10/07/2008 |
| 7431890 | Fluid system coupler A tissue processing system includes a tissue processor for processing tissue using reagent fluids, a fluid container and a coupler providing bi-direction fluid communication between the tissue processor and the fluid container. The coupler includes first and second ... | 10/07/2008 |
| 7419737 | Fuel supply device for direct methanol fuel cells A fuel supply device for direct methanol fuel cells includes a fuel tank for storing liquid fuel, a wick structure formed on the fuel tank, the wick structure for receiving the liquid fuel from the fuel tank, a sheet stack disposed on the wick structure, the sheet s... | 09/02/2008 |
| 7416896 | Determination of plasma total and unbound bilirubin using zone fluidics A method for determining total and bound plasma bilirubin. The method utilizes zone fluidics to enable accurate determination of the bilirubin using small volumes of sample and reagents, and significantly reduces dilution errors caused by inherent changes in bilirub... | 08/26/2008 |
| 7412990 | Microfluidic control device and method for controlling microfluid Provided is a microfluidic control device and method for controlling the microfluid, and a fine amount of fluid is controlled even with natural fluid flow and solution injection, wherein a pressure barrier of a capillary is removed by a surface tension change result... | 08/19/2008 |
| 7410615 | Precision liquid dispensing system A system for dispensing microdrops of reagent in small, precisely metered quantities maintains the fluid reagent to be dispensed in a reservoir under a controlled pressure. The reagent is dispensed through multiple nozzles connected to solenoid-actuated valves that ... | 08/12/2008 |
| 7402285 | Switch block having at least one attached or integrated reaction vessel Twelve reaction vessels (2) in two parallel rows are attached to a switch block (401). The switch block (401) comprises a reaction block (403) and twelve slide plates (404), which are arranged within it and which can be adjusted be... | 07/22/2008 |
| 7393508 | Valve arrangement The valve arrangement comprises a predetermined number of individual valve functionalities, arranged in a manner parallel to each other. A fixed connector plate (3) has a number of sample funnel tubes (6) and output connections (8) for forward t... | 07/01/2008 |
| 7387764 | Contained oxygen analyzing apparatus and contained analyzing method An apparatus for analyzing the amount of gas in a solid sample such as a contained oxygen analyzing apparatus and method utilizing a preliminary reducing furnace which can be connected to an analyzing furnace by a transfer unit. A sample such as steel can be reduced... | 06/17/2008 |
| 7384602 | Chemical analysis apparatus and genetic diagnostic apparatus In a chemical analysis apparatus for extracting a specific substance, such as nucleic acid, from a sample containing a plurality of chemical substances, solutions remaining in valves are prevented so that a reagent in an earlier step does not contaminate the subsequ... | 06/10/2008 |
| 7384605 | Fluidics system The present invention provides a fluidics system and a method for selectively drawing fluid from at least one selected reservoir into a channel by providing a negative pressure source downstream of the fluid and channel and selectively back filling the selected rese... | 06/10/2008 |
| 7378280 | Apparatus and methods for conducting assays and high throughput screening The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention... | 05/27/2008 |
| 7374722 | System for taking a gas sample able to contain particles of suspended materials The sampling system of the invention includes a column comprising a first separator associated with a first collector so as to extract particles whose diameter is larger than a first diameter, and a second separator associated with a second collector which eliminate... | 05/20/2008 |
| 7371247 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the pe... | 05/13/2008 |
| 7367358 | Medical fluid delivery system and method relating to the same A medical fluid delivery system for the use in the delivery of medical fluids. The medical fluid delivery system may include a pumping system, a disposable medical fluid line set and a valve operating system. The disposable tubing line set may include valves adapted... | 05/06/2008 |
| 7368080 | Smear preparing apparatus A smear preparing apparatus for preparing a smear of a specimen on a glass slide by using a spreader based on a smearing condition, the apparatus includes a memory for storing smearing conditions in connection with pertinent information required for establishing the... | 05/06/2008 |
| 7357852 | Bubble-free and pressure-generating electrodes for electrophoretic and electroosmotic devices Bubble-free electrodes, electrochemical cells including bubble-free electrodes, analytical devices, and methods for preparing and using them are provided. The analytical devices each include at least one bubble-free electrode. Analytical devices that include an elec... | 04/15/2008 |
| 7355045 | Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof In some embodiments, this invention pertains to isotopically enriched N-substituted piperazine acetic acids. In some embodiments, this invention pertains to methods for the preparation of isotopically enriched N-substituted piperazine acetic acids. ... | 04/08/2008 |
| 7354510 | Extracting apparatus A mechanism for introducing pressurized air into an extracting cartridge comprises an air pump, an on-off valve, and a pressure sensor for detecting an internal pressure within the extracting cartridge. The on-off valve is turned on in order to introduce the pressur... | 04/08/2008 |
| 7351380 | Microfluidic structures and methods for integrating a functional component into a microfluidic device Injection molding is used to form microfluidic devices with integrated functional components. One or more functional components are placed in a mold cavity which is then closed. Molten thermoplastic resin is injected into the mold and then cooled, thereby forming a ... | 04/01/2008 |