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| Number | Title | Issue Date |
| 8149506 | Cassette for facilitating optical sectioning of a retained tissue specimen A cassette for retaining a specimen of surgically exposed tissue from a patient in an orientation that facilitates optical sectioning of the tissue by a confocal microscopic or other optical imaging microscope. The cassette includes a base member having an optically... | 04/03/2012 |
| 7974003 | Photolithographed micro-mirror well for 3D tomogram imaging of individual cells A micro-mirror well. In one embodiment the micro-mirror well includes a plurality of planar mirrors arranged around an axis of symmetry and inclined to form a pyramid well, where each of the plurality of planar mirrors is capable of reflecting light emitting from an... | 07/05/2011 |
| 7885000 | Apparatus for imaging cells An apparatus for imaging cells including a culture chamber, in which a cultivation sub-structure is placed, imaging optics, and actuators for providing the relative movement of the cultivation substructure and the imaging optics in such a way that the imaging optics... | 02/08/2011 |
| 7583436 | Sampler carrier for a confocal microscope and method for fabricating a sample carrier A sample carrier (30) for microscopy, in particular for confocal microscopy, and a method for producing the sample carrier (30), are disclosed. The sample carrier (30) has a first coverslip (32) and a second coverslip (33). The sec... | 09/01/2009 |
| 7495827 | Sample tube handling apparatus A test tube (72, 72′) defines a test tube axis (75) and contains or supports an associated sample in an annular sampling region (12). At least two alignment bearings (80, 81, 81′, 82, 83, 110, 140, 142, 181, 182, 183, 184, 211, 212) e... | 02/24/2009 |
| 7382531 | Microscope and method of preventing dew condensation on objective lens The problem to be solved by the present invention is to provide a microscope that prevents a dew condensation on an objective lens and allows obtaining a good microscopic image, and a method of preventing a dew condensation on an objective lens. A microscope ... | 06/03/2008 |
| 7372626 | Device for sequential observation of samples and methods using same The invention concerns methods and devices for observing or analysing samples on a support. More particularly, it concerns a device for sequential observation of several samples arranged on a common plate (19) comprising an objective (15) for observing... | 05/13/2008 |
| 7355697 | Flow-through, thermal-expansion-compensated cell for light spectroscopy Optical cells are non-actively compensated to ensure that a sample gap of a sample space remains nearly constant upon a change in temperature. Fluids can be flowed through the sample space of the optical cells. ... | 04/08/2008 |
| 7345817 | Ceramic coating for parts of a microscope A microscope is disclosed which comprises several parts, such as a stand, a stage, a nose piece and several elements used to operate the microscope. At least one of these parts is provided with the ceramic layer on its surface. ... | 03/18/2008 |
| 7343257 | Method and system for device-independent determination of coordinates of a point displayed by means of a microscope A method for non-instrument-dependent determination of coordinates of a point imaged using a microscope includes determining, at object-related reference coordinates of at least one imaged reference point in a DICOM coordinate system, corresponding first instrument ... | 03/11/2008 |
| 7336417 | Method of measuring biological sample with high accuracy A displacement prevention sheet that, in order to inhibit a sample from deviating at the time of measurement with a microscope, is disposed between a sample holder in which the sample is set and a sample holder mounting stage on which the sample holder is mounted, w... | 02/26/2008 |
| 7329537 | Micro-pattern embedded plastic optical film device for cell-based assays In the present invention, a micro-pattern embedded optical film for cell-based assays is described. The optical film contains micro-patterns in the form of geometric shapes, such as lines and curves, and numbers and letters. Furthermore, the optical film contains a ... | 02/12/2008 |
| 7326560 | Tissue micro-array builder manual test The tissue micro-array (TMA) building manual set, which includes a well-known SZK tissue core punch extractor and a TMA block mould (1) characterized as follows: the TMA block mould (1) consists of a lower (2) and an upper (3) part, the l... | 02/05/2008 |
| 7274809 | Computerized methods and systems related to the detection of malignancy-associated changes (MAC) to detect cancer Computer programs, systems and the like related to processing, segmenting and feature normalizing digital images. The images are of cells and the methods are useful for the detection of malignancy-associated changes (MAC) in cells, which can be used for the detectio... | 09/25/2007 |
| 7247499 | Method for conducting binding reactions on a solid surface within an enclosed chamber The invention provides an apparatus and method for conducting chemical or biochemical reactions on a solid surface within an enclosed chamber. The invention may be used in conducting hybridization reactions, as of biopolymers such as DNA, RNA, oligonucleotides, pept... | 07/24/2007 |
| 7245368 | Sample chamber for microscopy A chamber is provided having a main body and one or two optical plates that are held to the main body by O-rings or other seal forming elements using forces created by vacuum and/or chemical adhesion. The chamber, in which a sample well holds a specimen, is formed f... | 07/17/2007 |
| 7238535 | Test cell for evaluating phosphor An test cell is adapted for both making and testing samples. The cell includes a bottom plate and a top plate having concentric apertures defining a central test cavity. A post attached to the bottom plate closes off the bottom of the test cavity. A slide closes off... | 07/03/2007 |
| 7235400 | Laminated microarray interface device A device for forming a low volume reaction chamber on a substrate such as a microarray slide and its method of use is disclosed. The reaction chamber forming device has an adhesive laminate design that permits it to be manufactured as a disposable device. A preferre... | 06/26/2007 |
| 7227630 | Imaging of surgical biopsies In order to determine, rapidly and without the delay required by conventional tissue preparation techniques for pathological examination (freezing, sectioning, staining, etc.), whether, an excision, which may be a biopsy sample, is representative of the morphology o... | 06/05/2007 |
| 7223363 | Method and system for microfluidic interfacing to arrays A method and system for providing a fluidic interface to slides bearing microarrays of biomolecules or other samples immobilized thereon to perform a variety of chemical reactions or processing steps on the slide. An interface device seals against the slide to form ... | 05/29/2007 |
| 7221447 | Consumable for laser capture microdissection Systems and methods for acquiring laser capture microdissection samples are disclosed. A scattering media is located within a beam path defined by the laser capture microdissection microscope and the sample is imaged through the scattering media. A transfer film car... | 05/22/2007 |
| 7215431 | Systems and methods for immersion metrology Fluid immersion technology can be utilized to increase the resolution and angular range of existing metrology systems. An immersion fluid placed between the metrology optics and the sample can reduce the refraction at the sample interface, thereby decreasing the spo... | 05/08/2007 |
| 7197355 | Variable-motion optical tomography of small objects Motion of an object of interest, such as a cell, has a variable velocity that can be varied on a cell-by-cell basis. Cell velocity is controlled in one example by packing cells into a capillary tube, or any other linear substrate that provides optically equivalent 3... | 03/27/2007 |
| 7194118 | System for optically sectioning and mapping surgically excised tissue A display (34) provides from digital images of an excised tissue specimen the orientation and location of tissue and regions of interest (cancers). Images of slices through excised specimen are obtained using a confocal microscope (10) to obtain confoc... | 03/20/2007 |
| 7186015 | Backlight display system An apparatus and method for backlighting a translucent image. At least one polymer thick film conductive strip is applied to a glass substrate, connecting a plurality of light emitting devices, a dropping resistor, and a power supply connection. The glass substrate ... | 03/06/2007 |
| 7139070 | Ultra-fast temperature switch for microscopic samples A device for producing rapid temperature changes around microscopic samples comprises two hollow channels (5,6) positioned at the same plane but at an angle to each other, FIG. 1. Streams of solutions (9, 10) flowing from the respective channels... | 11/21/2006 |
| 7138270 | Assay device and method for chemical or biological screening An assay device (1) comprises a base (2) and glass plate lid (3). The base (2) has an array of shallow microwells (4), each having a flat rim (9), all rims being co-planar. When the lid (3) is placed on the base (2... | 11/21/2006 |
| 7135331 | Apparatus for detecting biopolymers and cartridge Provided is an apparatus for detecting biopolymers (DNA) capable of total analysis including non-reacted samples without complicated operations such as washing. A DNA probe is fixed to one of electrodes and direct current voltage is placed between the electro... | 11/14/2006 |
| 7126692 | Device for holding measurement instruments A device for holding measurement instruments (2), in particular interferometers, is formed from a plurality of structure elements (4, 5, 6, 7) connected to one another and made from at least one material. The at least one material has a very low coeffi... | 10/24/2006 |
| 7119955 | Multi-aperture high-fill factor telescope A multi-aperture high-fill-factor telescope is provided. Specifically a multi-aperture high-fill-factor telescope is provided that includes a plurality of sub-aperture telescopes, each sub-aperture telescope being configured to collect electromagnetic radiation from... | 10/10/2006 |
| 7108833 | Sample tab A sample tab for retaining a sample during spectroscopic analysis includes a base plate, a sample well, and a cover plate. The sample well may vary in size to accommodate different sample volumes, and the base of the sample well may be positioned above or below the ... | 09/19/2006 |
| 7092154 | Apparatus for microscopic observation of long-term culture of single cell An apparatus is provided with a cell culture container having a cell culture region made of a hole formed on a substrate, a semi-permeable membrane covering a top plane of the cell culture region and a culture medium replacement part provided over the semi-permeable... | 08/15/2006 |
| 7091035 | Cell culturing and storage systems, devices and methods Featured is a long-term cell culture system being configured and arranged so as to be capable of monitoring the dynamic processes that occur during proliferation and differentiation of stem cells such as central nervous system (CNS) stem cells/embryonic stem cells. ... | 08/15/2006 |
| 7075640 | Consumable for laser capture microdissection Systems and methods for acquiring laser capture microdissection samples are disclosed. An integral portion of a biological reaction vessel includes a transfer film carrier having a substrate surface; and a laser capture microdissection transfer film coupled to the s... | 07/11/2006 |
| 7063774 | Recloseable biosensor A biosensor is provided that comprises a substrate, a sample site positioned on the substrate, a cover coupled to the substrate, and biocide positioned between the substrate and the cover. The biosensor may also include desiccant. The cover is operative to selective... | 06/20/2006 |
| 7062837 | Method for manufacturing a disk drive with a hinged head disk assembly enclosure A disk drive includes an enclosure that defines an exterior surface, the enclosure including a base, a cover and a hinge mechanically coupling the base to the cover such that the hinge forms a portion of the exterior surface of the enclosure. A spindle motor is atta... | 06/20/2006 |
| 7057808 | Slide staining device The slide staining device has a generally rectangular body which includes an upper rectangular frame and a lower rectangular frame. The upper rectangular frame and the lower rectangular frame are aligned and detachably connected together so that multiple microscope ... | 06/06/2006 |
| 7042639 | Identification of cells with a compact microscope imaging system with intelligent controls A Microscope Imaging System (CMIS) with intelligent controls is disclosed that provides techniques for scanning, identifying, detecting and tracking microscopic changes in selected characteristics or features of various surfaces including, but not limited to, cells,... | 05/09/2006 |
| 7023614 | Portable microscope having an illumination device, and microscope stage A portable microscope and a microscope stage (10) for a portable microscope are disclosed. The microscope comprises a stand (4) that carries the adjustable-height microscope stage (10). The microscope stage (10) is constructed from a samp... | 04/04/2006 |
| 7016033 | Counting chamber provided with a reference and method for manufacturing a counting chamber provided with a reference Disclosed is a counting chamber for optical detection of particles that are present in a fluid, comprising two substantially transparent and substantially parallel plates of material, between which the fluid can be introduced. At least one of the plates includes a v... | 03/21/2006 |
