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| Number | Title | Issue Date |
| 8168946 | Charged particle separation apparatus and charged particle bombardment apparatus A charged particle separation apparatus that separates ionized gas clusters is disclosed. The charged particle separation apparatus includes an electric field applying part including two electrodes across which electric voltage is applied in order to generate electr... | 05/01/2012 |
| 7714283 | Electrostatic trap An electrostatic trap such as an orbitrap is disclosed, with an electrode structure. An electrostatic trapping field of the form U′(r,φ,z) is generated to trap ions within the trap so that they undergo isochronous oscillations. The trapping field U′(r, φ,z) is... | 05/11/2010 |
| 7521673 | Wide range, very high resolution differential mobility analyzer (DMA) The resolution of a differential mobility analyzer (DMA) and the range of valid mobility values for the charged particles that it can detect are increased. The DMA makes use of a flat configuration and a purely two-dimensional operating model in which shims are used... | 04/21/2009 |
| 7432501 | Ionising particle analyser enabling for example the separation of the fluorescent yield (FY) and the total electron yield (TEY) in EXAPS (extended X-ray absorption fine structure) measurements An ionising particle analyser comprises a source of ionising particles, a charged particle detector, and an ionisable gas located between the source and the detector. The analyser further comprises a charged particle impeding device located between the source and th... | 10/07/2008 |
| 7417226 | Mass spectrometer An Atmospheric Pressure Chemical Ionisation (“APCI”) ion source is disclosed comprising a housing 14 having a corona discharge chamber 1, a reaction chamber 2 and a passage 6 connecting the corona discharge chamber 1 to the rea... | 08/26/2008 |
| 7402799 | MEMS mass spectrometer A MEMS mass spectrometer having metal walls connected between a lid and base, with the walls defining a plurality of interior chambers including sample gas input chambers, an ionizer chamber, a plurality of ion optics chambers and a ion separation chamber. A detecto... | 07/22/2008 |
| 7399962 | All-mass MS/MS method and apparatus A method of obtaining a mass spectrum of elements in a sample is disclosed. Sample precursor ions having a mass to charge ratio M/Z are generated, and fragmented at a dissociation site, so as to produce fragment ions of mass to charge ratio m/z. The fragment ions ar... | 07/15/2008 |
| 7399959 | Method and apparatus for enhanced ion based sample filtering and detection The invention provides, in various embodiments, systems and methods relating to enhancing the filtering and detection capability of ion mobility based systems by various techniques to counteract a charge buildup in the ion mobility based system. ... | 07/15/2008 |
| 7388196 | Hyperbolic horn helical mass spectrometer An improved rotating electric field ion mass spectrometer (REFIMS) provides for a smooth transition of the input ion beam from zero rotation to the desired level of field rotation. The REFIMS grid shape is changed from a fixed-diameter tunnel to that of a horn. The ... | 06/17/2008 |
| 7388197 | Multiplex data acquisition modes for ion mobility-mass spectrometry A method and apparatus for multiplexed data acquisition for gas-phase ion mobility coupled with mass spectrometry is described. Ion packets are injected into an ion mobility drift chamber at a rate faster than the ion mobility separation arrival time distribution. T... | 06/17/2008 |
| 7385187 | Multi-reflecting time-of-flight mass spectrometer and method of use A multiple reflecting time-of-flight mass spectrometer (MR-TOF MS) and method of analysis are disclosed. The flight path of ions is folded along a trajectory by electrostatic mirrors. The longer flight path provides higher resolution while maintaining a moderate ins... | 06/10/2008 |
| 7378651 | High field asymmetric waveform ion mobility spectrometer FAIMS Disclosed is an apparatus for separating ions including a plurality of first electrode portions, each first electrode portion of the plurality of first electrode portions having a first length and an outer surface that is at least partially curved in a direction tra... | 05/27/2008 |
| 7368709 | Low field mobility separation of ions using segmented cylindrical FAIMS A method of separating ions is disclosed. The method includes a step of providing a FAIMS analyzer region for separating ions, the FAIMS analyzer region including at least one region of segmentation. The segmentation permits ion trapping, and a combination trapping ... | 05/06/2008 |
| 7365316 | Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry Method and apparatus for chromatographic high field asymmetric waveform ion mobility spectrometry, including a gas chromatographic analyzer section intimately coupled with an ionization section, an ion filter section, and an ion detection section, in which the sampl... | 04/29/2008 |
| 7351960 | Enhanced ion desolvation for an ion mobility spectrometry device An ion spectrometer apparatus is disclosed having an ion source, an ion mobility spectrometer device such as a FAIMS cell, and a capillary for transporting ions from the ion source to the entrance of the FAIMS cell. The capillary is heated to promote evaporation of ... | 04/01/2008 |
| 7339164 | Systems and methods for ion mobility control The invention provides, in various embodiments, systems and methods relating to controlling ion behavior in an ion-based analysis system. ... | 03/04/2008 |
| 7335897 | Method and system for desorption electrospray ionization A new method and system for desorption ionization is described and applied to the ionization of various compounds, including peptides and proteins present on metal, polymer, and mineral surfaces. Desorption electrospray ionization (DESI) is carried out by directing ... | 02/26/2008 |
| 7329866 | Two-dimensional ion trap mass spectrometry A two-dimensional ion trap comprises a first and second trapping plate located in a first and second terminals of the ion trap device, a set of four predetermined surface-shaped rods located in the center, a set of electrodes located between the set of four predeter... | 02/12/2008 |
| 7326925 | Multi-reflecting time-of-flight mass spectrometer with isochronous curved ion interface The present invention relates generally to a multi-reflecting time-of-flight mass spectrometer (MR TOF MS). To improve mass resolving power of a planar MR TOF MS, a spatially isochronous and curved interface may be used for ion transfer in and out of the MR TOF anal... | 02/05/2008 |
| 7326941 | Apparatus and methods for ion beam implantation using ribbon and spot beams This invention discloses an ion implantation apparatus with multiple operating modes. It has an ion source and an ion extraction means for extracting a ribbon-shaped ion beam therefrom. The ion implantation apparatus includes a magnetic analyzer for selecting ions w... | 02/05/2008 |
| 7317192 | High energy polyenergetic ion selection systems, ion beam therapy systems, and ion beam treatment centers Devices and methods are provided for generating laser-accelerated high energy polyenergetic positive ion beams that are spatially separated and modulated based on energy level. The spatially separated and modulated high energy polyenergetic positive ion beams are us... | 01/08/2008 |
| 7276103 | Method and device for separating molecules having different excitation spectra The invention relates to a method for the separation of molecules having different excitation spectra, which form components of a gas. The molecules are excited by laser pulses in a way that the molecules to be separated are transferred into a state of excitation du... | 10/02/2007 |
| 7268358 | Method of modulating laser-accelerated protons for radiation therapy Methods of optimizing a laser-accelerated proton radiation dose to a targeted region are disclosed. Disclosed methods include providing a plurality of modulated polyenergetic proton beamlets and irradiating the targeted region with the plurality of modulated beamlet... | 09/11/2007 |
| 7265347 | Multiple nano-spray delivery system for FAIMS An apparatus for multiple nano-spray delivery of a sample to FAIMS analyzer includes a micro-machined ionization source having a plurality of discrete nozzles. At least some of the discrete nozzles of the plurality are aligned one each with an ion inlet of a plurali... | 09/04/2007 |
| 7244931 | Ion mobility spectrometer with parallel running drift gas and ion carrier gas flows An ion mobility spectrometer is provided including at least one ionization chamber (1), which can be passed through by analyte-containing gas and at least one radiation source (2), from which ionizing radiation which is suitable for at least partially ... | 07/17/2007 |
| 7223967 | Side-to-side FAIMS apparatus having an analyzer region with non-uniform spacing and method therefore Disclosed is a high field asymmetric waveform ion mobility spectrometer (FAIMS) having a side-to-side electrode geometry. The FAIMS includes an inner electrode (102) having a length and an outer surface that is curved in a direction transverse to the length. ... | 05/29/2007 |
| 7223971 | Method and apparatus for selecting inlets of a multiple inlet FAIMS An ion introduction system for selecting ions from one of two separate ionization sources of ions is provided. The system includes a plate having a hole formed therethrough, the plate for being disposed adjacent an ion introduction region of a gas phase ion analyzer... | 05/29/2007 |
| 7186972 | Time of flight mass analyzer having improved mass resolution and method of operating same A time-of-flight mass analyzer having improved mass resolution without mandating a corresponding increase in instrument size is disclosed. The analyzer includes an ionizer that generates the ions that are to be analyzed. These ions are introduced to an ion flight pa... | 03/06/2007 |
| 7176452 | Microfabricated beam modulation device A beam modulation device gate is constructed from a silicon material, such as a silicon layer on an silicon on insulator wafer. The device further comprises a set of electrical contacts on the layer. The layer defines a set of electrically conducting silicon materia... | 02/13/2007 |
| 7148477 | System for trajectory-based ion species identification Method and apparatus for field ion mobility spectrometry for identification of chemical compounds in a sample by trajectory of sample ions in a transverse electric field. ... | 12/12/2006 |
| 7135689 | Apparatus and method for ion production enhancement The present invention relates to an apparatus and method for use with a mass spectrometer. The ion enhancement system of the present invention is used to direct a heated gas toward ions produced by a matrix based ion source and detected by a detector. The ion enhanc... | 11/14/2006 |
| 7135674 | Method and apparatus for FAIMS with a laser-based ionization source A method of separating ions comprises applying a spot of a sample material to a target plate. The target plate is mounted in fluid communication with an ion inlet orifice of a FAIMS analyzer region and externally to the FAIMS analyzer region. Using a laser light sou... | 11/14/2006 |
| 7132670 | Apparatus and method for ion production enhancement The present invention relates to an apparatus and method for use with a mass spectrometer. The ion enhancement system of the present invention is used to direct a heated gas toward ions produced by a matrix based ion source and detected by a detector. The ion enhanc... | 11/07/2006 |
| 7122794 | Systems and methods for ion mobility control The invention provides, in various embodiments, systems and methods relating to controlling ion behavior in an ion-based analysis system. ... | 10/17/2006 |
| 7115861 | Spectrograph time of flight system for low energy neutral particles A mass spectrometer is provided for identifying mass and velocity distributions in a continuous ion beam is configured with a circular dispersive system creating a rotating electromagnetic field, which is capable of deflecting the ion beam from an initial direction,... | 10/03/2006 |
| 7112788 | Apparatus and method for controllably affecting the temperature of FAIMS components An apparatus for separating ions includes providing a FAIMS analyzer region defined by a space between a first electrode surface and a second electrode surface and extending between an ion inlet end and an ion outlet end. An asymmetric waveform is applied to the fir... | 09/26/2006 |
| 7112789 | High aspect ratio, high mass resolution analyzer magnet and system for ribbon ion beams The present invention provides a windowframe magnet having an aligned array of paired bedstead coils in mirror symmetry can bend a high aspect ratio ribbon ion beam through angle of not less than about 45 degrees and not more than about 110 degrees, and can focus it... | 09/26/2006 |
| 7109475 | Leading edge/trailing edge TOF detection Disclosed are a time-of-flight mass spectrometer and signal processing electronics. The signal processing electronics include a plurality of time-to-digital converters configured to receive signal pulses from the same detector anode within the time-of-flight mass sp... | 09/19/2006 |
| 7091482 | Apparatus and method for ion production enhancement The present invention relates to an apparatus and method for use with a mass spectrometer. The ion enhancement system of the present invention is used to direct a heated gas toward ions produced by a matrix based ion source and detected by a detector. The ion enhanc... | 08/15/2006 |
| 7081621 | Laminated lens for focusing ions from atmospheric pressure A thin laminated high transmission electro-optical lens populated with a plurality of apertures in communication with its laminates used to improve the collection, focusing, and selection of ions generated from atmospheric pressure sources, such as electrospray, atm... | 07/25/2006 |
