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| Number | Title | Issue Date |
| 8080785 | High pressure collision cell for mass spectrometer A high pressure collision cell for use in a mass spectrometer. The high pressure collision cell has a cell length L selected to be in a range such that upon application of voltages to a pair of opposed elongate electrically conducting electrodes there is produced an... | 12/20/2011 |
| 8080786 | Mass spectrometer An electron capture dissociation device to implement a combination of electron capture dissociation and collision dissociation and a mass spectrometer with the use thereof are provided. This device includes a linear ion trap provided with linear multipole electrodes... | 12/20/2011 |
| 8080787 | Ion mobility measurement at a potential barrier Ion mobilities are measured by entraining the ions in a gas and adiabatically expanding the ion-containing gas through a nozzle to form a gas jet. An electrical field barrier with variable height is located at the nozzle exit. The field barrier may be located adjace... | 12/20/2011 |
| 8044349 | Mass spectrometer A mass spectrometer includes a linear multipole electrode, an auxiliary electrode that applies a DC potential on the center axis of the linear multipole electrode, and a DC power supply that supplies a DC power to the auxiliary electrode. The DC potential slope form... | 10/25/2011 |
| 8030612 | High resolution excitation/isolation of ions in a low pressure linear ion trap Methods for improved separation of ions from an ion trap employing a combination of low pressure and low amplitude ion excitation, including methods for removing, from an ion trap ion population, ions having a m/z value neighboring that of an ion of interest, mass s... | 10/04/2011 |
| 7999223 | Multiple ion isolation in multi-reflection systems This invention relates to a method of operating a charged particle trap in which ions undergo multiple reflections back and forth and/or follow a closed orbit around, usually, a set of electrodes. The invention allows high-performance isolation of multiple ion speci... | 08/16/2011 |
| 7947950 | Energy focus for distance of flight mass spectometry with constant momentum acceleration and an ion mirror A distance-of-flight mass spectrometer (DOF-MS) imparts constant momentum acceleration to ions in an ion source and uses an ion mirror to enhance energy focusing. Embodiments of DOF-MS with ion mirror are shown. Further, a method of compensating for the dispersion o... | 05/24/2011 |
| 7943902 | Method for introducing ions into an ion trap and an ion storage apparatus A method of introducing ions into an ion trap and an ion storage apparatus are described. Introduction means are used to introduce first ions into an ion trap through an entrance aperture to the ion trap. An operating condition of the introduction means is adjusted ... | 05/17/2011 |
| 7935922 | Ion guide chamber An ion guide chamber comprising a gas-tight elongate chamber, at least one first electrode for generating a field for transporting ions along the elongate chamber and at least one second electrode for generating a field for focusing ions within the elongate chamber.... | 05/03/2011 |
| 7928371 | Methods for penning trap mass spectroscopy A method of mass spectroscopy according to example embodiments may include injecting ions into a Penning trap and exciting the ions into cyclotron and/or magnetron motions. The cyclotron motions and magnetron motions may be converted to one another with external rad... | 04/19/2011 |
| 7893402 | Measurement of the mobility of mass-selected ions The mobility of mass-selected ions in gases is measured at pressures of a few hectopascal by selecting the ions under investigation in a quadrupole filter according to their mass-to-charge ratio m/z, measuring their mobility in a drift region at a pressure of a few ... | 02/22/2011 |
| 7855360 | Method and apparatus to accurately discriminate gas phase ions with several filtering devices in tandem A method for fast and accurate recognition of species contained in trace amounts in complex mixtures such as ambient air or biological fluids is taught based on the use in tandem of one or several differential mobility analyzers (DMAs) and possibly also a mass spect... | 12/21/2010 |
| 7847247 | Method of plasma particle simulation, storage medium, plasma particle simulator and plasma processing apparatus A method of plasma particle simulation capable of preventing solution divergence. A space within a housing chamber of a plasma processing apparatus is divided into a plurality of cells. A weighting factor corresponding to the number of plasma particles represented b... | 12/07/2010 |
| 7847246 | Collision-induced decomposition of ions in RF ion traps In an RF ion trap, analyte ions are fragmented by applying a moderately high RF storage voltage to the trap. The ions are then excited via dipolar excitation, and after a short time, the ions are forced into a resting state, again using dipolar excitation. The RF st... | 12/07/2010 |
| 7842918 | Chemical structure-insensitive method and apparatus for dissociating ions In a method for exciting a precursor ion in an ion trap, the ion is trapped in a nonlinear trapping field that includes a quadrupolar field and a multipole field. The quadrupolar field is generated by applying a radio-frequency (RF) trapping voltage to the ion trap ... | 11/30/2010 |
| 7842919 | Q-pole type mass spectrometer A Q-pole type mass spectrometer can be used under a high-pressure atmosphere of more than 0.1 Pa. The Q-pole type mass spectrometer can analyze the mass of gas molecules continuously, and can separate mass properly even if an ion is injected at high speed in order t... | 11/30/2010 |
| 7829850 | Branched radio frequency multipole Systems and methods of the invention include a branched radio frequency multipole configured to act, for example, as an ion guide. The branched radio frequency multipole comprises multiple ion channels through which ions can be alternatively directed. The branched r... | 11/09/2010 |
| 7829849 | Mass spectrometer A device (6) for separating ions according to differences in their ion mobility as a function of electric field strength is disclosed. The device (6) comprises an upper electrode (7a), a lower electrode (7b) and a plurality ... | 11/09/2010 |
| 7812309 | Apparatus and method for an electro-acoustic ion transmittor A method of transmitting ions along an analyzer region between closely spaced electrodes is disclosed. The method includes providing an analyzer region for transmitting ions, the analyzer region in fluid communication with an ionization source and with an ion detect... | 10/12/2010 |
| 7772549 | Multiplexed tandem mass spectrometry One or more methods for determination and/or deconvolution of complex mass spectra, using quadrupole ion trap mass spectrometry. ... | 08/10/2010 |
| 7772550 | Electronic drive and acquisition system for mass spectrometry The present invention discloses an mixed signal RF drive electronics board that offers small, low power, reliable, and customizable method for driving and generating mass spectra from a mass spectrometer, and for control of other functions such as electron ionizer, ... | 08/10/2010 |
| 7759641 | Ion trap mass spectrometer In a mass spectrometer in which a high ion dissociation efficiency is possible, inserted electrodes are arranged with a form divided into two or more in the axial direction of the ion trap, an electric static harmonic potential is formed from a DC voltage applied to... | 07/20/2010 |
| 7718959 | Storage bank for ions The invention relates to instruments for storing ions in more than one ion storage device and to the use of the storage bank thus created. The ion storage bank includes several storage cells configured as RF multipole rod systems, where the cells contain damping gas... | 05/18/2010 |
| 7714282 | Apparatus and method for forming a gas composition gradient between FAIMS electrodes A method of separating ions includes providing a FAIMS analyzer region for separating ions, the FAIMS analyzer region in fluid communication with an ionization source and with an ion detecting device. The method further includes affecting a gas composition within a ... | 05/11/2010 |
| 7692142 | Differential-pressure dual ion trap mass analyzer and methods of use thereof A dual ion trap mass analyzer includes adjacently positioned first and second two-dimensional ion traps respectively maintained at relatively high and low pressures. Functions favoring high pressure (cooling and fragmentation) may be performed in the first trap, and... | 04/06/2010 |
| 7671330 | High resolution mass spectrometry method and system for analysis of whole proteins and other large molecules A matrix assisted laser desorption/ionization (MALDI) method and related system for analyzing high molecular weight analytes includes the steps of providing at least one matrix-containing particle inside an ion trap, wherein at least one high molecular weight analyt... | 03/02/2010 |
| 7638765 | FAIMS cell with separate desolvation and carrier gas inlets A method for analyzing ions includes providing a desolvation chamber in communication with an analytical gap of a FAIMS analyzer, via an ion inlet orifice. A flow of ions is introduced into the desolvation chamber along a flow path that is toward the ion inlet orifi... | 12/29/2009 |
| 7598488 | Apparatus and method for field asymmetric ion mobility spectrometry combined with mass spectrometry In a system for analyzing samples by mass spectrometry, analyte ions are analyzed first by field asymmetric ion mobility spectrometry (FAIMS) before being analyzed by a mass analyzer. The analyte ions are produced in an ion source operating at near atmospheric press... | 10/06/2009 |
| 7589320 | Mass spectrometer An electron capture dissociation device to implement a combination of electron capture dissociation and collision dissociation and a mass spectrometer with the use thereof are provided. This device includes a linear ion trap provided with linear multipole electrodes... | 09/15/2009 |
| 7582864 | Linear ion trap with an imbalanced radio frequency field An imbalanced radio frequency (RF) field creates a retarding barrier near the exit aperture of a multipole ion guide, in combination with the extracting DC field such that the barrier provides an m/z dependent cut of ion sampling. Contrary to the prior art, the mass... | 09/01/2009 |
| 7468511 | FAIMS electrodes with lateral ion focusing A FAIMS cell including one of side-to-side cylindrical geometry electrodes and stacked-plate electrodes is adapted with a medial surface feature for focusing ions along a lateral direction within an ion separation region of the FAIMS cell. The medial surface feature... | 12/23/2008 |
| 7442921 | Protein profiles with atmospheric pressure ionization The invention relates to the acquisition of mass spectra of complex protein mixtures, often called protein profiles, for example to search for biomarkers which indicate stress situations, or to identify microbes. Up to now protein profiles have been acquired using i... | 10/28/2008 |
| 7435953 | Quadrupole mass filter length selection In this invention the technology is provided for rod shaped conductor member fabrication in situ, in position, in the mass filter spatial configuration by growth through vertically repeated conduit mold formations, filling the conduit increments with to be rod mater... | 10/14/2008 |
| 7435950 | Micromachined field asymmetric ion mobility filter and detection system A micromechanical field asymmetric ion mobility filter for a detection system includes a pair of spaced substrates defining between them a flow path between a sample inlet and an outlet; an ion filter disposed in the path and including a pair of spaced filter electr... | 10/14/2008 |
| 7435951 | Ion source sample plate illumination system The invention provides a mass spectrometry system ion source containing a sample plate and an illumination device that is configured to produce a light beam that contacts the sample plate surface to define a grazing angle between the light beam and the sample plate ... | 10/14/2008 |
| 7432516 | Rapid cycling medical synchrotron and beam delivery system A medical synchrotron which cycles rapidly in order to accelerate particles for delivery in a beam therapy system. The synchrotron generally includes a radiofrequency (RF) cavity for accelerating the particles as a beam and a plurality of combined function magnets a... | 10/07/2008 |
| 7429730 | SIFT-MS instruments A SIFT or SIFDT apparatus in which the upstream quadrupole and the downstream quadrupole are housed within a single evacuated chamber with the upstream quadrupole being connected to the downstream quadrupole by a curved flow tube. In a preferred form the interior of... | 09/30/2008 |
| 7425699 | Mass spectrometry method and apparatus A mass spectrometer 10 comprises an ion source 12 which generates nebulized ions which enter an ion cooler 20 via an ion source block 16. Ions within a window of m/z of interest are extracted via a quadrupole mass filter 24 and pas... | 09/16/2008 |
| 7420161 | Branched radio frequency multipole Systems and methods of the invention include a branched radio frequency multipole configured to act, for example, as an ion guide. The branched radio frequency multipole comprises multiple ion channels through which ions can be alternatively directed. The branched r... | 09/02/2008 |
| 7411185 | Atmospheric pressure ionization mass spectrometer system An atmospheric pressure ionization mass spectrometry system has an atmospheric pressure ionization chamber for ionizing a sample, an evacuated intermediate evacuation chamber into which generated ions are introduced through a capillary tube, and a vacuum chamber fur... | 08/12/2008 |
