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| Number | Title | Issue Date |
| 8008619 | High sensitivity mass spectrometer interface for multiple ion sources An interface for mass spectrometers. The interface uses non coaxial sampling pathways of the analyte ion beam prior to entering the entrance of a mass spectrometer for decreasing chemical background, and can be done in such a way as to permit multiple sprayers, incr... | 08/30/2011 |
| 7928364 | Sampling system for containment and transfer of ions into a spectroscopy system The invention provides for efficient collection of analyte ions and neutral molecules from surfaces for their subsequent analysis with spectrometry. In an embodiment of the invention, a ‘multiple desorption ionization source’ includes a tube which can contain io... | 04/19/2011 |
| 7687771 | High sensitivity mass spectrometer interface for multiple ion sources An interface for mass spectrometers. The interface uses non coaxial sampling pathways of the analyte ion beam prior to entering the entrance of a mass spectrometer for decreasing chemical background, and can be done in such a way as to permit multiple sprayers, incr... | 03/30/2010 |
| 7679053 | Multiple sample sources for use with mass spectrometers, and apparatus, devices, and methods therefor A method for introducing samples through a boundary member partially defining a chamber at an entrance point coaxial to a sampling inlet of a mass spectrometer is described. Field-free conditions can be established in at least one region of the chamber. The sample c... | 03/16/2010 |
| 7528366 | Method and apparatus for multiplexing plural ion beams to a mass spectrometer A method and apparatus for multiplexing plural ion beams to a mass spectrometer. At least two ion sources are provided with means of transporting the ions from the ion sources to separate two-dimensional ion traps. Each ion trap is used for storage and transmission ... | 05/05/2009 |
| 7439499 | Multiple electrospray probe interface for mass spectrometry In one embodiment, an analytical apparatus is provided that includes a carriage; and a plurality of electrospray probes pivotably mounted on the carriage, wherein movement of the carriage engages a feature with a selected one of the electrospray probes whereby movem... | 10/21/2008 |
| 7435951 | Ion source sample plate illumination system The invention provides a mass spectrometry system ion source containing a sample plate and an illumination device that is configured to produce a light beam that contacts the sample plate surface to define a grazing angle between the light beam and the sample plate ... | 10/14/2008 |
| 7429730 | SIFT-MS instruments A SIFT or SIFDT apparatus in which the upstream quadrupole and the downstream quadrupole are housed within a single evacuated chamber with the upstream quadrupole being connected to the downstream quadrupole by a curved flow tube. In a preferred form the interior of... | 09/30/2008 |
| 7427751 | High sensitivity slitless ion source mass spectrometer for trace gas leak detection A mass spectrometer includes a main magnet having spaced-apart polepieces which define a gap, the main magnet producing a magnetic field in the gap, an ion source to generate ions and to accelerate the ions into the magnetic field in the gap, the ion source located ... | 09/23/2008 |
| 7420180 | Mass spectrometer and mass spectrometry A mass spectrometer capable of measuring under switching two ion sources at different pressure levels in which a sample gas separated by GC column is branched, and separately introduced to a first ion source (for example, APCI ion source) and a second ion source (fo... | 09/02/2008 |
| 7397027 | Multi-channel high-field asymmetric waveform ion mobility spectrometry A multi-channel high field asymmetric waveform ion mobility spectrometer (FAIMS) is provided. The apparatus provides for substantially simultaneous FAIMS analysis of plurality of ions from a single sample. The apparatus has a analyzer region comprising a hollow elec... | 07/08/2008 |
| 7397026 | Efficient electron transfer dissociation for mass spectrometry The present invention relates to, inter alia, methods and apparatuses for electron transfer dissociation (ETD) that vary the internal energy of precursor ions for ETD. The methods and apparatuses are particularly useful in mass spectrometry. ... | 07/08/2008 |
| 7397029 | Method and apparatus for ion fragmentation in mass spectrometry An apparatus for mass analyzing molecules includes a mass spectrometer configured to select precursor ions having a mass to charge ratio range, a metastable species generator configured to generate a metastable species for introduction into the mass spectrometer, an... | 07/08/2008 |
| 7391020 | Electrospray apparatus with an integrated electrode The invention provides related apparatus and methods of making an integrated electrospray tip by depositing ionic and/or electronic conductor materials onto a planar substrate. The invention also features methods of forming an electrospray apparatus comprising coupl... | 06/24/2008 |
| 7385185 | Molecular activation for tandem mass spectroscopy In a tandem mass spectrometer means are provided for molecular activation of ions prior to fragmentation. An embodiment of a tandem mass spectrometer comprises a first collision cell receiving analyte ions having an internal energy and a second collision cell situat... | 06/10/2008 |
| 7378653 | Increasing ion kinetic energy along axis of linear ion processing devices In a method for increasing the kinetic energy of an ion in a linear electrode structure, axial motion of the ion is constrained substantially to a selected axial end the electrode structure. The ion is driven to move axially from the selected end toward the other en... | 05/27/2008 |
| 7378652 | Nebulizer with plasma source A combination electrospray/microwave induced plasma (MIP) ionization source is used as the ionization source for a mass spectrometer. The electrospray can be operated in positive mode, negative mode, or it can be switched off. The microwave-induced plasma can also b... | 05/27/2008 |
| 7378651 | High field asymmetric waveform ion mobility spectrometer FAIMS Disclosed is an apparatus for separating ions including a plurality of first electrode portions, each first electrode portion of the plurality of first electrode portions having a first length and an outer surface that is at least partially curved in a direction tra... | 05/27/2008 |
| 7375316 | Mass spectrometer and mass spectrometry A mass spectrometer capable of measuring under switching two ion sources at different pressure levels in which a sample gas separated by GC column is branched, and separately introduced to a first ion source (for example, APCI ion source) and a second ion source (fo... | 05/20/2008 |
| 7372042 | Lens device for introducing a second ion beam into a primary ion path The invention provides a device for introducing ions into the primary ion path of a mass spectrometry system. In general, the device contains an electrical lens having a primary ion passageway and a secondary ion passageway that merges with the primary ion passagewa... | 05/13/2008 |
| 7364913 | Direct flow injection analysis nebulization electrospray and APCI mass spectrometry A method and apparatus for Flow Injection Analysis (FIA) into Atmospheric Pressure Ion sources (API) including Electrospray (ES) and Atmospheric Pressure Chemical Ionization (APCI) sources whereby the sampling and spray needles are one and the same. The sampling and... | 04/29/2008 |
| 7361888 | Method and apparatus for multiplexing plural ion beams to a mass spectrometer A method and apparatus for multiplexing plural ion beams to a mass spectrometer. At least two ion sources are provided with means of transporting the ions from the ion sources to separate two-dimensional ion traps. Each ion trap is used for storage and transmission ... | 04/22/2008 |
| 7358488 | Mass spectrometer multiple device interface for parallel configuration of multiple devices A multi-device interface for use in mass spectrometry for interfacing one or more ion sources to one or more downstream devices. The multi-device interface comprises three or more multipole rod sets configured as either an input rod set or an output rod set dependin... | 04/15/2008 |
| 7355169 | Method of selectively inhibiting reaction between ions A method of inhibiting the reaction between ions of opposite polarity is disclosed. The method includes exposing a population of ions to a resonance excitation frequency during a mass-to-charge altering reaction between a first subpopulation of ions and a second sub... | 04/08/2008 |
| 7351963 | Multiple rod systems produced by wire erosion The invention relates to a method of creating multipole systems carrying RF voltage which can be used as ion guides, mass-selective quadrupole filters or collision cells to fragment ions; and multipole systems manufactured according to this method. The invention pro... | 04/01/2008 |
| 7342224 | Obtaining tandem mass spectrometry data for multiple parent ions in an ion population This invention relates to tandem mass spectrometry and, in particular, to tandem mass spectrometry using a linear ion trap and a time of flight detector to collect mass spectra to form a MS/MS experiment. The accepted standard is to store and mass analyze precursor ... | 03/11/2008 |
| 7317186 | Short torch design for direct liquid sample introduction using conventional and micro-nebulizers for plasma spectrometry An apparatus and method for providing direct liquid sample introduction using a nebulizer are provided. The apparatus and method include a short torch having an inner tube and an outer tube, and an elongated adapter having a cavity for receiving the nebulizer and po... | 01/08/2008 |
| 7315020 | Ionization chamber for atmospheric pressure ionization mass spectrometry The ionization chamber consists of a plurality of ports to accept multiple identical devices or varying devices. Ports may be arranged at various positions on the ionization chamber and at various angles with respect to the sampling orifice leading into the vacuum c... | 01/01/2008 |
| 7297939 | Mass spectrometer A mass spectrometer includes an ion detector positioned upstream of a quadrupole mass filter/analyser. Ions are passed through the quadrupole mass filter/analyser, stored in an ion trap and then passed back through the same mass filter/analyser before being detected... | 11/20/2007 |
| 7294830 | Simultaneous acquisition of chemical information A method and apparatus for operating a mass spectrometer include providing at least two different ion sources, and coupling ion streams simultaneously from the at least two different ion sources to the spectrometer. Another method of operating a spectrometer include... | 11/13/2007 |
| 7265348 | Apparatus for dispensing a sample in electrospray mass spectrometers The present invention relates to an apparatus to dispense a sample for subsequent electrospray ionisation (ESI) mass spectrometry (MS) analysis, to a method of fabricating such apparatus and to applications of such apparatus in biological and chemical analysis. The ... | 09/04/2007 |
| 7260483 | Real-time detection method and system for identifying individual aerosol particles An improved method and system of identifying individual aerosol particles in real time. Sample aerosol particles are collimated, tracked, and screened to determine which ones qualify for mass spectrometric analysis based on predetermined qualification or selection c... | 08/21/2007 |
| 7223971 | Method and apparatus for selecting inlets of a multiple inlet FAIMS An ion introduction system for selecting ions from one of two separate ionization sources of ions is provided. The system includes a plate having a hole formed therethrough, the plate for being disposed adjacent an ion introduction region of a gas phase ion analyzer... | 05/29/2007 |
| 7223966 | Time-of-flight mass spectrometers with orthogonal ion injection The invention relates to time-of-flight mass spectrometers, equipped with ion reflector and ion detector, with orthogonal ion injection and outpulsing of a segment of the ion beam perpendicular to the direction of injection in a pulser. The invention is directed to ... | 05/29/2007 |
| 7217919 | Method and apparatus for multiplexing plural ion beams to a mass spectrometer A method/apparatus for multiplexing plural ion beams to a mass spectrometer. At least two ion sources are provided with means of transporting the ions from the ion sources to separate two-dimensional ion traps. Each ion trap is used for storage and transmission of t... | 05/15/2007 |
| 7217920 | Pancake spectrometer Method and apparatus for identification of chemical compounds in a sample based on differences in ion mobility, wherein the filter and detector electrodes are formed radially spaced on facing substrates. ... | 05/15/2007 |
| 7205536 | Micro matrix ion generator for analyzers A source of ions for an analyzer includes a reservoir for containing a liquid, a manifold having a plurality of nozzles, a conduit connecting the reservoir to the manifold and a counter electrode having a potential different between the counter electrode and the noz... | 04/17/2007 |
| 7205537 | Ion guides with movable RF multiple segments The invention relates to an ion guide consisting of RF multipole segments to transfer ions from an ion source into a mass analyzer. The invention consists in having movable RF multipole segments in the ion guide which extend or electrically connect other RF multipol... | 04/17/2007 |
| 7199363 | Mass spectrometer A mass spectrometer is disclosed comprising an ion source 4, a field free or drift region 5 and an ion mirror 7 comprising a reflectron. Metastable parent ions which spontaneously fragment by Post Source Decay whilst passing through the field fr... | 04/03/2007 |
| 7196326 | Mass spectrometer and reaction cell for ion-ion reactions The invention relates to a reaction cell for reactions between different types of ion species and a related mass spectrometer to analyze the ion products. The invention consists in an RF-operated straight ion guide with a side inlet, particularly suitable for reacti... | 03/27/2007 |
