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| Number | Title | Issue Date |
| 8182696 | Multicolumn sequential separation process A process is disclosed for separating biomolecules from an aqueous solution containing the biomolectules and impurities, having different affinities and/or interactions with a solid support. The solution is passed over a fixed bed of chromatographic resin containing... | 05/22/2012 |
| 8177980 | Separation of a mixture of polyhydric alcohols The present invention provides methods of separating at butanediol compound from a mixture containing polyhydric alcohols and butanediol compounds. The mixture of polyhydric alcohols typically contains propylene glycol and ethylene glycol in addition to the butanedi... | 05/15/2012 |
| 8158004 | Method of manufacturing substances by supercritical fluid chromatography Provided is a method of manufacturing target substances with use of supercritical fluid chromatography, by which the following are achieved: solution of a problem at the time of sequential injections of samples containing the target substances; an increase of a trea... | 04/17/2012 |
| 8123950 | Process and apparatus for simulated moving bed separation comprising bypass lines in every other bed and with a modulated bypass fluid flow rate A process for separating a feed F by simulated moving bed adsorption in a SMB device is described, the device comprising external bypass lines Li/i+1 which directly connect two successive plates Pi, Pi+1, the index i being either eve... | 02/28/2012 |
| 8123952 | Process and device for simulated moving bed separation with a modulated by-pass fluid flow A process for separating a feed F by simulated moving bed adsorption in a SMB device comprises at least one zone 1 for desorption of the compounds produced in the extract, a zone 2 for desorption of the compounds produced in the raffinate, a zone 3 for adsorption of... | 02/28/2012 |
| 8123951 | Process and apparatus for simulated moving bed separation comprising bypass lines in every other bed and with controlled flushing flow rates during injections and withdrawals A process for separating a feed F by simulated moving bed adsorption in a SMB device comprises external bypass lines Li/i+1 which directly connect two successive plates, Pi, Pi+1, the index “i” being either even or (exclusive of ... | 02/28/2012 |
| 8110113 | High-throughput evaluation of Rubisco and plant photosynthetic performance in vivo The present invention provides a method for determining a level of a RuBP, PGA, 2-PA in a photosynthetic cellular extract by resolving at least one RuBP, PGA, or 2-PA or combinations thereof in a photosynthetic cellular extract obtained from a plant. In another aspe... | 02/07/2012 |
| 8088282 | Sieving media from planar arrays of nanoscale grooves, method of making and method of using the same Disclosed herein are an apparatus and a method for separating molecules on the basis of size and or structure, and to a method of making the apparatus. Generally, the separation method includes passing a fluid comprising particles having different effective molecula... | 01/03/2012 |
| 7959812 | Multi-column sequenced separation process for separating an ionic metal derivative The subject of the present disclosure is a multi-column sequenced separation process and a drive for implementing this process. The disclosure applies particularly to the separation of metal derivatives such as uranium, nickel, copper, cobalt and other precious meta... | 06/14/2011 |
| 7959811 | Separation process The present invention relates to a chromatographic separation process for fractionating solutions containing sugars, sugar alcohols, sugar acids and/or betaine by utilizing fractions comprising parts of the separation profile as a substituent of the eluent in a nove... | 06/14/2011 |
| 7906026 | Sieving media from planar arrays of nanoscale grooves, method of making and method of using the same Disclosed herein are an apparatus and a method for separating molecules on the basis of size and or structure, and to a method of making the apparatus. Generally, the separation method includes passing a fluid comprising particles having different effective molecula... | 03/15/2011 |
| 7901581 | Chromatography method The present invention relates to a simulated moving bed process, wherein at least one adsorbent is washed after binding of target compound and wherein the outlet of wash liquid from the adsorbent is subsequently passed onto another adsorbent for binding of target co... | 03/08/2011 |
| 7790040 | Continuous isocratic affinity chromatography The present invention provides devices and methods for micro-scale simulated moving bed chromatography (SMB) for continuous preparation of analytic quantities of highly pure fractions of target molecules. The present apparatus and method of the invention is adapted ... | 09/07/2010 |
| 7749389 | Filler used for separating optical isomers and process for separating optical isomers with the filler The objectives of this invention are to provide a filler for separating optical isomers, capable of efficiently carrying out optical resolution of optical isomer mixtures, and to provide a process for separating optical isomers by a simulated moving bed chromatograp... | 07/06/2010 |
| 7749390 | Semi-continuous chromatographic method and corresponding device for the separation of binary and multi-component mixtures The invention relates to a semi-continuous chromatographic method for the separation of binary and multi-component mixtures and corresponding devices. ... | 07/06/2010 |
| 7615159 | Method for the production of chemical and pharmaceutical products with integrated multicolumn chromatography The invention relates to a chromatographic process for substance separation in the context of the preparation of chemicals such as, for example, chiral pharmaceuticals, isomers or biomolecules on the small-scale and production scale, based on Simulated Moving Bed (S... | 11/10/2009 |
| 7488422 | Method and apparatus for separating a target molecule from a liquid mixture A simulated moving bed apparatus and methods are described for continuously separating a target molecule from a liquid mixture, using a simulated moving bed system. The simulated moving bed system includes a plurality of filter cartridge modules in serial fluid comm... | 02/10/2009 |
| 7479228 | Method and device for chromatographic component separation The invention relates to a process for the chromatographic separation of components (19, 20, 25, 26, 28, 29) of a multiple-component fluid mixture (2a) by means of the Simulated Moving Bed process, in which the multiple-component fluid mixture (... | 01/20/2009 |
| 7473368 | Simulated moving bed separation process and device A simulated moving bed (SMB) separation device comprises at least one column, beds of adsorbent arranged in this column, trays Pi with a chamber Ci for distribution and extraction of fluids, a multi-way rotary valve for the distribution of the fluids feeding or leav... | 01/06/2009 |
| 7413660 | Single pass method and apparatus for separating a target molecule from a liquid mixture A single pass simulated moving bed apparatus and methods are described for continuously separating a target molecule from a liquid mixture, using a simulated moving bed system. The simulated moving bed system includes a plurality of filter cartridge modules in seria... | 08/19/2008 |
| 7410586 | Purification or work-up on ionic liquids by means of adsorptive separation processes Process for the work-up of a mixture comprising ionic liquids and a further substance, wherein the substance present is separated off by means of adsorptive separation processes. ... | 08/12/2008 |
| 7407586 | Chromatographic separation The invention relates to an equipment for fractionating a solution by a sequential SMB process, which equipment comprises a feed column and one or several other columns, which include a chromatographic separation resin bed. The equipment of the invention is characte... | 08/05/2008 |
| 7402250 | Equipment and method for feeding liquid gradient in nano/micro liquid chromatography It is an object of the present invention to improve the performance of gradient liquid transfer in nano/micro liquid chromatographs when solvents are mixed. In a gradient liquid transfer device and method for a nano/micro liquid chromatograph, an opening and ... | 07/22/2008 |
| 7399415 | Parking a sample stream and suppressing the sample Pretreatment method and apparatus to remove matrix ions from a liquid sample, prior to separation of the sample analytes (e.g. by chromatography), by flowing the liquid sample into a sample compartment and stopping the flow. The sample compartment has a wall compris... | 07/15/2008 |
| 7399898 | Simulated moving bed adsorptive separation process for preventing increase in pressure drop and system thereof Disclosed is a simulated moving bed (SMB) adsorptive separation system in which at least one component of a fluid mixture is brought into contact with a solid adsorbent and the adsorbed component is desorbed with a desorbent, wherein the improvement comprises an ine... | 07/15/2008 |
| 7396469 | Backflow prevention for high pressure gradient systems Gradient performance with high pressure gradient solvent delivery system is optimized by approximation of infinite stroke volume of high pressure pumps by the addition of pulse dampening with backflow prevention to each high pressure pump. The backflow prevention ad... | 07/08/2008 |
| 7390412 | Method of managing the valves of a simulated moving bed separation system A method of managing the valves of a simulated moving bed separation system comprising at least one column of adsorbent beds split into several zones delimited by injection and draw-off points, allowing finer monitoring of a determined concentration profile. The met... | 06/24/2008 |
| 7373255 | Method and system for determination of molecular interaction parameters A method of determining kinetic parameters for a reversible molecular interaction between a ligand immobilized to a solid support surface and a binding partner to the ligand in solution, comprises sequentially, without intermediate regeneration or renewal of the imm... | 05/13/2008 |
| 7371913 | Selective aromatics isomerization process A process for isomerizing xylenes while retaining ethylbenzene in a C8-aromatics stream in liquid phase uses a gallium-substituted pentasil zeolite in the absence of hydrogen. ... | 05/13/2008 |
| 7368620 | Two-stage aromatics isomerization process This invention is drawn to a process for isomerizing a non-equilibrium mixture of alkylaromatics in two sequential zones, the first zone operating in the absence of hydrogen using a platinum-free catalyst and the second zone using a catalyst comprising a molecular s... | 05/06/2008 |
| 7368282 | Process and device for determining the activity of enzymes in liquids, or the concentration and/or activity of inhibitors in liquids A process and device are disclosed to determine the activity of enzymes in liquids in a largely automatic manner. The device for carrying out this process has a column (1) with a chromatographic carrier for treating a measurement sample. The carrier is mixed ... | 05/06/2008 |
| 7361273 | Separation of sugars, sugar alcohols, carbohydrates and mixtures thereof The present invention relates to a method of separating sugars and sugar alcohols from each other. More particularly the present invention relates to the use of a weakly basic anion exchange resin in a chromatographic separation process. The advantage of the present... | 04/22/2008 |
| 7361269 | Fraction collector with adjustable tray A fraction collector comprising a movable tray is provided. The movable tray may be attached to the fraction collector support system in a variety of ways and adjusted without adjusting the parts of the fraction collector support system. The moveable tray may be sta... | 04/22/2008 |
| 7347936 | Liquid chromatograph A liquid chromatograph has switching valves as a flow passage switching mechanism and an automatic sampler as an injection section. The liquid chromatograph can switch, by switching the switching valves between a concentration flow passage for concentrating the samp... | 03/25/2008 |
| 7347942 | Cyclic aeration system for submerged membrane modules An aeration system for a submerged membrane module has a set of aerators connected to an air blower, valves and a controller adapted to alternately provide a higher rate or air flow and a lower rate of air flow in repeated cycles. In an embodiment, the air blower, v... | 03/25/2008 |
| 7332087 | Flow sensing apparatus used to monitor/provide feedback to a split flow pumping system A method and apparatus for monitoring and controlling the nano-scale flow rate of fluid in the operating flow path of a HPLC system without relying on a nano-scale sensor in the operating flow path. A main flow sensor is disposed in the main flow path between the pu... | 02/19/2008 |
| 7332080 | Apparatus for salt free water softening A water softening system and process for softening water on an as needed basis is disclosed. The system and process softens water without the addition of a substitute metal exchange cation. ... | 02/19/2008 |
| 7326353 | Methods for reclaiming developing solvents The present invention relates to an improved method for reclaiming and recycling developing solvents used in the production of flexographic printing plates. More specifically, the invention relates to reclaiming and/or recycling of the developing solvent through cen... | 02/05/2008 |
| 7318900 | Chromatography system and method A chromatography system and method for analyzing a sample of interest. The chromatography system can include a housing, a cartridge holder coupled to the housing and formed to hold a chromatography cartridge containing a stationary phase, a collection vessel stand h... | 01/15/2008 |
| 7314528 | Crystallization of sugars The invention relates to removing crystallization inhibitors from a solution comprising one or more reducing sugars by nanofiltration, hydrolysis and/or chromatography. The reducing sugars are typically selected from fructose and xylose. ... | 01/01/2008 |
