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| Number | Title | Issue Date |
| 8187468 | Preparation and use of chiral zeolites for liquid chromatography The present invention relates to the preparation of chiral zeolites and their use in liquid chromatography. The zeolite material may be used in the chromatographic separation of mixtures of components, such as the separation of enantiomers. ... | 05/29/2012 |
| 8173022 | Method for manufacturing packing material, packing material, and column A method for manufacturing a packing material includes a first step of reacting an inorganic particle having a hydroxyl group with a silane coupling agent including a silane coupling agent having an alkenyl group with a carbon number of 2 or more and 8 or less and/o... | 05/08/2012 |
| 8158003 | Precision peak matching in liquid chromatography-mass spectroscopy A method that identifies common peaks among unidentified peaks in the data from different LC-MS or LC-MS/MS runs is provided. The method employs an algorithm, herein referred to as “Precision Peak Matching (PPM).” The different runs can be from different laborat... | 04/17/2012 |
| 8153009 | Apparatus and methods for mass-spectrometric directed purification of biopolymers A method for extracting at least one target compound from a sample includes injecting an overloaded amount of the sample into a chromatographic conduit (110), and flowing a solvent having a time-varying composition through the conduit (110). An apparat... | 04/10/2012 |
| 8137563 | Preparation of polysaccharide beads The present invention relates a method of preparing agarose beads, which method results in a population of beads which are of relatively uniform particle size. In an advantageous embodiment, the beads are of a particle size less than 10 μm, and the coefficient of v... | 03/20/2012 |
| 8133395 | Automated column packing method A method for automatically without any required manual interaction packing a media bed in a column (3) from a slurry being a dispersion of said media particles and a liquid, said method comprising the steps a)-f) which all are performed automatically: a) fill... | 03/13/2012 |
| 8123949 | Methods for separating compounds Methods and systems for analyzing samples using multi-dimensional chromatography are disclosed. ... | 02/28/2012 |
| 8114295 | Intelligent system and method for automated packing of chromatography columns The present invention provides an automated system and method for packing chromatography columns. In one embodiment, the system first determines the type of media that is present in the column, and uses this information to generate an automated procedure to pack the... | 02/14/2012 |
| 8070957 | Flash chromatography cartridge A low pressure liquid chromatographic cartridge is provided having a tubular polymer container adapted to receive a chromatographic packing material. The container has an outlet port located at a downstream end of the container and container threads formed on an ups... | 12/06/2011 |
| 8070956 | Method of separation of polymers A method of using electrokinetics for separating particles in a buffer solution is provided, where a chromatographic column is provided having a non-uniform internal longitudinal cross-section. At least one main inlet for inputting solution and at least one main out... | 12/06/2011 |
| 8070958 | Separation matrix having a ligand density gradient The present invention relates to a separation matrix comprised of ligands coupled to the surfaces of a porous support, such as one or more porous particles, wherein the ligands provide at least one chemical gradient within the support. In the most advantageous embod... | 12/06/2011 |
| 8066882 | Column packing method A method for packing a media bed in a column (3) from a slurry being a dispersion of said media particles and a liquid, said method comprising the steps of: a) estimating a slurry concentration; b) filling the column (3) with a certain volume of the sl... | 11/29/2011 |
| 8048312 | Separation analyzer A separation analyzer for transferring solutions, while changing mixing ratios of the solutions, wherein a flow passage from a first pump, a flow passage from a second pump, and a passage for sample introduction section, the flow passages being connected, which furt... | 11/01/2011 |
| 8021555 | Recycled suppressor regenerants A suppressed ion chromatographic apparatus using a regenerant recycle loop, comprising (a) an ion separation device, (b) a membrane suppressor, (c) a detector, (d) a container for regenerant solution, (e) a first conduit between the ion separation device and the sup... | 09/20/2011 |
| 8017017 | Method for producing a target substance using a simulated moving bed chromatography separation system Disclosed is a method for producing a target substance by separating it from a mixture using a simulated moving bed chromatography (SMBC) separation system, which can minimize decreases in separation performance due to interference from a liquid accumulation portion... | 09/13/2011 |
| 7959810 | Method for adapting a detection device to be coupled to a liquid chromatography column and equipped with means for forming and conveying an aerosol The present invention relates to a method for adapting a detection device to be coupled to a liquid chromatography column and equipped with means for forming and conveying an aerosol as well as means for the formation of an aerosol and the conveyance thereof towards... | 06/14/2011 |
| 7862724 | Preparative liquid chromatograph system and preparative separation/purification method using the same A technique for extracting an objective component from a sample solution and obtaining the component in the form of equally separated powder aliquots is provided. A peak detector 12 detects the start point of the peak of the objective component on a chromatog... | 01/04/2011 |
| 7846336 | Chromatographic methods The current invention comprises a method for the regeneration of a cation exchange chromatography column. ... | 12/07/2010 |
| 7846335 | Device for chromatographic separations A device is provided for chromatographic separations comprising a manifold comprising a plurality of connectors for connecting to one or more chromatographic separation columns and/or feed or extraction tubing. At least one central duct is formed between at least tw... | 12/07/2010 |
| 7846337 | Superficially porous particles and methods of making and using same Disclosed are porous-shell particles, methods of making the particles, and uses thereof. In one aspect, the porous-shell particles are superficially porous particles. ... | 12/07/2010 |
| 7837881 | Method and device for chromatographic purification A process for continuous purification of a multi-component mixture by means of individual chromatographic columns though which the mixture is fed by means of at least one solvent. The multi-component mixture comprises at least light impurities, an intermediate produ... | 11/23/2010 |
| 7828978 | Simultaneous synthesis and purification of a fatty acid monoester biodiesel fuel Simultaneous synthesis and purification of a fatty acid monoester biodiesel fuel from a triacylglycerol feedstock is described. In an exemplary method, the triacylglycerol feedstock is continuously contacted with a catalytic chromatographic bed comprising a first (s... | 11/09/2010 |
| 7785472 | Carbon nanotube structure-selective separation and surface fixation A method of separating, concentrating or purifying uniform carbon nanotubes with desired properties (diameter, chiral vector, etc) in a highly sensitive manner by the use of structure-sensitive properties peculiar to carbon nanotubes; and an apparatus therefor. Ther... | 08/31/2010 |
| 7785473 | Chromatography column and method of maintenance A chromatography column and method of maintenance is described which does not require the use of a hoist or crane for disassembly. The method provides improved operator safety by reducing the need for the operator to work below a suspended or supported load within t... | 08/31/2010 |
| 7780853 | Method for conducting maintenance on a chromatography column The present invention relates to methods for conducting maintenance on chromatography columns used in industrial-scale chromatography. In particular, the invention is concerned with safer methods for performing maintenance on such columns, such as cleaning and repla... | 08/24/2010 |
| 7776220 | Pre-filled columns for flash chromatography with higher separating efficiency A column for flash chromatography having spherical, or semi-spherical, and porous silica gel having a granule size between 3 and 45 μm and pores between 30 and 300 Å. ... | 08/17/2010 |
| 7767090 | System for automated compression of chromatography columns The present invention provides an automated system and method for maintaining compaction, and therefore increased efficiency, of a media bed within a chromatography column. In the preferred embodiment, an adjustment assembly is slidingly engaged inside one end of th... | 08/03/2010 |
| 7749388 | Low volume filtration column devices and methods of filtering therewith This relates to filter columns for isolating nucleic acids, particularly at small elution volumes. The filter column is adapted for stable placement within the upper portion of standard plastic collection tubes of various sizes. The body of the filter column has a n... | 07/06/2010 |
| 7744762 | Microfluidic devices and methods facilitating high-throughput, on-chip detection and separation techniques The present invention provides a microfluidic device and method for facilitating on-chip complex sample processing and detection. In general, the device comprises at least a separation channel of a separation system, an interface, and an array of microreservoirs dis... | 06/29/2010 |
| 7727403 | Automated simultaneous separation system for radionuclides in multiple samples and a method for automatically separating uranium (U) using the same Disclosed herein are an automated simultaneous separation system for radionuclides in multiple samples and a method for automatically separating uranium (U) using the same, which can automatically and simultaneously separate multiple samples. The automated simultane... | 06/01/2010 |
| 7727401 | Selective purification of mono-terpenes for removal of oxygen containing species A process for purifying monoterpenes, including the steps of: providing a monoterpene comprising alpha terpinene of about 90% or greater purity and comprising an oxygen-containing impurity compound selected from the group consisting of 1,8-cineole, ... | 06/01/2010 |
| 7727402 | Dual-chamber chromatographic cartridge A chromatography cartridge with a packed bed is manufactured from an inner and outer chamber, the inner chamber being in an insert that is slidable into the outer chamber with openings in each such that a slurry that is originally placed in the interior of the outer... | 06/01/2010 |
| 7708891 | Chromatography column and method of maintenance A chromatography column and method of maintenance is described which does not require the use of a hoist or crane for disassembly. The method provides improved operator safety by reducing the need for the operator to work below a suspended or supported load within t... | 05/04/2010 |
| 7699990 | Separation analyzer A separation analyzer for transferring solutions, while changing mixing ratios of the solutions, wherein a flow passage from a first pump, a flow passage from a second pump, and a passage for sample introduction section, the flow passages being connected, which furt... | 04/20/2010 |
| 7686958 | Method for the production of a chemical reaction product with the aid of a fixed-bed reactor Disclosed is a method for producing at least one chemical reaction product by chemically reacting one or several reactants that is/are optionally dissolved in one or several solvents and is/are supplied as a feed stream by bringing the same in contact with a heterog... | 03/30/2010 |
| 7686959 | Control system and method for flash separation Provided are methods and apparatus for determining conditions for performing chromatography, particularly flash chromatography. The methods may be utilized for separating compounds in a sample in a column chromatography system. The method includes determining at lea... | 03/30/2010 |
| 7674383 | Method and apparatus for packing chromatography columns A slurry chamber is fastened to and held in coaxial alignment with a chromatography column by a V-band. One end of the column has an end cap and frit. A slurry of fluid and chromatographic media is placed in the column and chamber. A piston is forced through the cha... | 03/09/2010 |
| 7648636 | Mixed-modal anion-exchanged type separation material The present invention relates to mixed-modal anion-exchange materials composed of a support on which a ligand is immobilized. The ligand combines at least one basic domain based on cyclic monobasic derivatives with two or more rings as anion-exchange domain and at l... | 01/19/2010 |
| 7645388 | Flow rate control A liquid sample is prepared at a preparation site and then processed, e.g. in an HPLC column. The sample is prepared and conveyed to the device at a flow rate which is substantially less than the flow rate through the device. The different flow rates are preferably ... | 01/12/2010 |
| 7635433 | System and method for feature alignment In a system and method for feature alignment in chromatographic systems, the system runs a first sample through a first separation column. The system determines a first set of features for the first sample run. The system runs a second sample through a second separa... | 12/22/2009 |
