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| Number | Title | Issue Date |
| 8187453 | Triglyceride and cholesterol sensing method and sensor A method for the determination of the amount of cholesterol in a sample is provided. The method typically provides a breakdown of the HDL and LDL cholesterol contents of the sample. ... | 05/29/2012 |
| 8163160 | Biosensor having improved hematocrit and oxygen biases The present invention provides reagent compositions, and analyte measuring devices and methods that utilize the reagent compositions. ... | 04/24/2012 |
| 8152992 | Cell-based sensing: biological transduction of chemical stimuli to electrical signals (nose-on-a-chip) Methods and compositions for the reliable detection of chemical stimuli using a “nose-on-a-chip” are presented. The invention uses cells sensitive to chemical stimuli and detects and processes the signals given by the cells upon contact with chemical stimuli. | 04/10/2012 |
| 8137529 | Methods of using an electrochemical biosensor According to one embodiment of the present invention, an electrochemical sensor (10) for detecting the concentration of analyte in a fluid test sample is disclosed. The sensor (10) includes a counter electrode having a high-resistance portion for use i... | 03/20/2012 |
| 8128803 | Method and system for determining the concentration of an analyte/enzyme complex or of an analyte/enzyme conjugate, especially for the electrochemical detection of the analyte, and corresponding measuring device A method follow the change in concentration of a redox-active substance, whereby suitable potentials for a reduction process or an oxidation process are applied to the working electrode of a measuring device. The potential of the working electrode is pulsed and meas... | 03/06/2012 |
| 8128802 | Analysis apparatus and analysis method for glycosylated hemoglobin Disclosed is a method for calculating a ratio of glycosylated hemoglobin with high accuracy by electrochemically detecting the concentration of fructosyl valine or fructosyl valyl-histidine in a sample. Also disclosed is an apparatus for assaying glucose and glycosy... | 03/06/2012 |
| 8101062 | System and methods for determination of analyte concentration using time resolved amperometry A method for determining a concentration of an analyte is disclosed. The method includes applying a potential excitation to a fluid sample containing an analyte and determining if a current decay curve associated with the fluid sample has entered an analyte depletio... | 01/24/2012 |
| 8101063 | Method of measuring quantity of substrate A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring devi... | 01/24/2012 |
| 8097147 | Method of measuring quantity of substrate A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring devi... | 01/17/2012 |
| 8092668 | System and method for quality assurance of a biosensor test strip The present invention provides a test strip for measuring a signal of interest in a biological fluid when the test strip is mated to an appropriate test meter, wherein the test strip and the test meter include structures to verify the integrity of the test strip tra... | 01/10/2012 |
| 8083924 | Small volume in vitro analyte sensor and methods of making A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffus... | 12/27/2011 |
| 8083925 | Analyte determination methods and devices The present invention provides methods and apparatuses for analyte detection. ... | 12/27/2011 |
| 8080153 | Analyte determination methods and devices The present invention provides methods and apparatuses for analyte detection. ... | 12/20/2011 |
| 8070934 | Transition metal complexes with (pyridyl)imidazole ligands Novel transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators in enzyme-based electrochemical sensors. The transition metal complexes include substituted or unsubstitute... | 12/06/2011 |
| 8048289 | Parallel patch clamp system A system for high-throughput analysis of membranous samples having ion channels including at least one membranous sample, a multi-compartment structure including an extracellular chamber, an opposing intracellular chamber and a partition separating the extracellular... | 11/01/2011 |
| 8025788 | Method for manufacturing an enzymatic reagent ink A method for manufacturing an enzymatic reagent ink for use in analytical test strips (such as electrochemical-based analytical test strips configured for the determination of glucose in blood) includes determining a first relationship between wetability of a repres... | 09/27/2011 |
| 8012341 | Biosensor electrode mediators for regeneration of cofactors The present invention is based on the discovery of NAD+ and NADP+ mediator compounds that do not bind irreversibly to thiol groups in the active sites of intracellular dehydrogenase enzymes. Such mediator compounds avoid a common mode of enzyme... | 09/06/2011 |
| 8007656 | Enzymatic electrochemical biosensor An electrochemical sensor strip has a base and a first electrode and a second electrode on the base. An oxidoreductase enzyme and a mediator are on the first electrode, and a soluble redox species is on the second electrode. The soluble redox species may be an organ... | 08/30/2011 |
| 8002965 | Oxidizable species as an internal reference in control solutions for biosensors Testing of the performance of an electrochemical meter used to measure the presence of an analyte in a biological sample, particularly glucose in whole blood, includes introducing a control solution containing a predetermined amount of the analyte and a predetermine... | 08/23/2011 |
| 7998337 | Biosensor electrode mediators for regeneration of cofactors The present invention is based on the discovery of NAD+ and NADP+ mediator compounds that do not bind irreversibly to thiol groups in the active sites of intracellular dehydrogenase enzymes. Such mediator compounds avoid a common mode of enzyme... | 08/16/2011 |
| 7998336 | Biosensor A biosensor comprises a space part for sucking and housing a sample formed of two upper and lower plates, the two plates being stuck together by an adhesive layer, the space part for sucking and housing the sample being constituted so as to be partially opened in th... | 08/16/2011 |
| 7993512 | Electrochemical test sensor An electrochemical test sensor for detecting the concentration of an analyte in a sample. The electrochemical test sensor comprises a base that provides a flow path for the fluid test sample having a counter electrode and a working electrode on its surface in electr... | 08/09/2011 |
| 7988845 | Integrated lancing and measurement device and analyte measuring methods An integrated lancing and measurement device is provided comprising a sensor designed to determine the amount and/or concentration of analyte in a biological fluid having a volume of less than about 1 μl. A piercing member is adapted to pierce and retract from a si... | 08/02/2011 |
| 7972494 | Application of biosensor chips A method of sensing a property of each of a plurality of samples is disclosed. The method includes disposing a sensor chip in each sample, the sensor chip being adapted to sense the property of a respective sample and comprising sensing electronics, a wireless commu... | 07/05/2011 |
| 7955492 | Method for measuring blood components and biosensor and measuring instrument for use therein The present invention provides a method of measuring a component in blood, by which the amounts of blood cells and an interfering substance can be measured with high accuracy and high reliability and the amount of the component can be corrected accurately based on t... | 06/07/2011 |
| 7955493 | Method of measuring the number of bacteria, device of measuring the number of bacteria and cell used in the device A method of measuring the number of bacteria according to the present invention includes step (a) through step (d). First, in step (a), a to-be-measured sample (specimen) including a predetermined bacterial strain (such as Escherichia coli or coliform bacteri... | 06/07/2011 |
| 7922891 | Methods for detection and quantification of analytes The present invention relates to a method for detecting and quantitating NADH/NAD+ and/or NADPH/NADP+ as well as NADHJNAD+ and/or NADPH/NADP+ dependent enzymes using a photoelectrochemical cell. ... | 04/12/2011 |
| 7918988 | Biosensor A biosensor comprises a space part for sucking and housing a sample formed of two upper and lower plates, the two plates being stuck together by an adhesive layer, the space part for sucking and housing the sample being constituted so as to be partially opened in th... | 04/05/2011 |
| 7909983 | System and methods for automatically recognizing a control solution Methods and devices for automatically distinguishing between a control solution and an actual patient/user sample in a biosensor are provided. The solution is introduced into an electrochemical cell having a working and counter electrode. Electric pulses are applied... | 03/22/2011 |
| 7906009 | Small volume in vitro analyte sensor A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 μL. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between ... | 03/15/2011 |
| 7850839 | Biosensor, measuring instrument for biosensor, and method of quantifying substrate A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring devi... | 12/14/2010 |
| 7833406 | Gene detection method, and intercalator A gene detection method for detecting a gene having a specific sequence with high sensitivity is provided. The gene detection method comprises a double-stranded nucleic acid formation step of forming double-stranded nucleic acid by hybridizing a nucleic acid probe i... | 11/16/2010 |
| 7815788 | Creatinine sensor calibration In a method for calibrating a biosensor for the amperometric determination of creatinine in biological liquids, consisting of one electrode system each for measuring the concentrations of creatinine and creatine, with at least two calibration solutions being used, t... | 10/19/2010 |
| 7807042 | System for and method of patch clamp analysis A system and method for automated patch clamp analysis of biological tissue such as cellular membrane. A biological membrane is applied to a porous semiconductor substrate, and laser energy is imparted thereon. Voltage clamped electrodes detect current across the me... | 10/05/2010 |
| 7794584 | pH-change sensor and method pH-change sensors and related methods are disclosed. One such sensor may have a first ion-sensitive transistor-operational-transconductance-amplifier (the “first IOTA”) and a second ion-sensitive transistor-operational-transconductance-amplifier (the “second I... | 09/14/2010 |
| 7780841 | E-field induced ion selective molecular deposition onto sensor arrays A sensor array for sensing at least one of chemical moieties and biological moieties is provided. The sensor array comprises a plurality of working electrodes electrically associated with a reference electrode, each working electrode in combination with the referenc... | 08/24/2010 |
| 7718048 | Base sequence detecting electrode, base sequence detecting device and base sequence detecting method A conductive detecting electrode (2), first blocking molecules (21) formed so as to cover a surface of the detecting electrode (2), the first blocking molecules decreasing adsorption of an intercalating agent to the surface of the detecting elec... | 05/18/2010 |
| 7699973 | Rapid analyte measurement assay The present the invention provides methods, devices and systems for rapidly measuring analytes within a biological sample. ... | 04/20/2010 |
| 7695609 | Nanobiosensor and carbon nanotube thin film transistors The present invention is directed to systems and methods for detecting biological and chemical species in liquid and gaseous phase. The systems and methods utilize carbon nanotubes to enhance sensitivity and selectivity towards the reacting species by decreasing int... | 04/13/2010 |
| 7691255 | Sensor, measuring device, and measuring method A sensor capable of measuring a plurality of measuring items quickly and accurately, a measuring device, and a measuring method are provided. The sensor includes a sample-holding unit for holding a sample containing an analyte; a sample-supplying port for supplying ... | 04/06/2010 |
