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| Number | Title | Issue Date |
| 7749369 | Gel processing and transfer device The present invention relates to a gel processing and transfer device, useful for the processing and transferring un-damaged and intact gel with minimal handling, said device comprising at least 4 separable components namely: a base plate for holding the gels with f... | 07/06/2010 |
| 7425254 | Fractionation of macro-molecules using asymmetric pulsed field electrophoresis A method and apparatus for fractionation of charged macro-molecules such as DNA is provided. DNA solution is loaded into a matrix including an array of obstacles. An alternating electric field having two different fields at different orientations is applied. The alt... | 09/16/2008 |
| 7399394 | Electrophoresis device, electrophoresis method using an electrophoresis device and use of the electrophoresis device An electrophoresis device having a separation chamber that is provided with at least one sample inlet on the inlet side and outlets (9) for the electrophoretically treated sample species on the outlet side. The separation chamber is divided into two chamber p... | 07/15/2008 |
| 7384527 | Electrophoresis apparatus and a plate therefor The invention provides an electrophoresis apparatus comprising an electrophoretic chamber containing at least on two-plate housing for a sieving matrix, each said at least one two-plate housing consisting of a cover plate and a plate for housing said sieving matrix,... | 06/10/2008 |
| 7264703 | Gel trap for electrophoresis An apparatus for electrophoresis having a first gel matrix, adapted for performing an electrophoretic process therein, in communication with a second gel matrix, both being accommodated within a suitable housing. The housing has a first opening adapted to permit ion... | 09/04/2007 |
| 7037419 | Concentration of protein and/or peptides samples The invention relates to a device for protein and/or peptide concentration, which device comprises electroconcentration means (23); at least two electrodes having a positive (7) and a negative charge (35), respectively; and protein and/or peptid... | 05/02/2006 |
| 6942775 | Vertical electrophoresis system A plugging medium is used to block the bottom opening of cassettes for vertical electrophoresis in order to facilitate filling the cassettes with separation media. Cassettes can be filled within a vertical electrophoresis system in which electrophoresis is conducted... | 09/13/2005 |
| 6942774 | Electrophoresis apparatus and a method of using the same An apparatus for rehydrating and for performing electrophoresis on a gel strip includes a tray defining a plurality of parallel troughs configured to receive gel strips. Each trough defines a centrally located rehydration area and an electrode area disposed either s... | 09/13/2005 |
| 6837977 | Capillary electrophoresis method for screening for affinity ligands using a detectable competitive ligand The invention relates to a capillary electrophoresis-based method of screening complex materials for any unidentified affinity ligand that binds to a target of interest. The method subjects a plug of a mixture of the target and a complex material sample, and a separ... | 01/04/2005 |
| 6783648 | Method and apparatus for unloading gels from isoelectric gel tubes An apparatus for expressing and unloading an isoelectric focusing gel from an electrophoresis gel tube includes a first support for supporting the gel tube, a plunger rod and a second support for supporting the plunger rod. The first support is mounted on a movable ... | 08/31/2004 |
| 6761810 | Automated apparatus including a robotic arm for loading samples into wells for first dimension electrophoresis separation An automated assembly for performing first dimension electrophoresis is described herein that includes a supply magazine, an electrophoresis tank and an automated transferring device that robotically transfers biological samples from sample vials retained in the sup... | 07/13/2004 |
| 6743344 | Coating of pre-cast electrophoresis slab gels In pre-cast slab gel cassettes, the formation of pathways in which proteins can migrate between the gel and the walls of the cassette to form shadow bands is avoided by the application of a coating of a nonionic amphiphilic polymer to the cassette walls. The coating... | 06/01/2004 |
| 6685811 | Method for separation of macromolecules The invention relates to a method and a system, suitable for automation, for the, preferably preparative, separation of amphoteric macromolecules, e.g. proteins or peptides, wherein said method comprises the steps of: (a) subjecting said mixture of macrom... | 02/03/2004 |
| 6682641 | Electrophoresis assembly and method of casting electrophoresis gels The invention provides an electrophoresis cassette to cast electrophoresis gels and to separate and analyze molecular components by electrophoresis. The electrophoresis cassette comprises a top plate assembly, a spacer and a bottom plate. The top plate as... | 01/27/2004 |
| 6537434 | First dimension electrophoresis separation method and apparatus An automated apparatus for carrying out a first dimension electrophoresis separation of proteins and other macromolecules includes a supply magazine, an automated transferring device and an electrophoresis tank. The supply magazine includes a carousel for... | 03/25/2003 |
| 6524866 | Capillary electrophoretic method to detect target-binding ligands and to determine their relative affinities The invention relates to capillary electrophoretic methods for detecting ligands or hit compounds that can bind to a selected target at or above a selected binding strength. The method allows one to rank various ligands based on their relative affinity, i... | 02/25/2003 |
| 6277258 | Device and method for focusing solutes in an electric field gradient An electrophoretic device and method for focusing a charged solute is disclosed. The device includes a first chamber for receiving a fluid medium, the first chamber having an inlet for introducing a first liquid to the chamber and an outlet for exiting th... | 08/21/2001 |
| 6139709 | Apparatus for producing electrophoresis gels A device and apparatus for producing ultra-thin electrophoresis gels formed between spaced-apart plates is provided, where at least one of the plates has a plurality of grooves, the device comprising a spacer comb having extensions formed thereon which ar... | 10/31/2000 |
| 6129828 | Apparatus and methods for active biological sample preparation Systems and methods for the electronic sample preparation of biological materials utilize the differential charge-to-mass ratio and/or the differential affinity of sample constituents to separation materials for sample preparation. An integrated system is... | 10/10/2000 |
| 6113766 | Device for rehydration and electrophoresis of gel strips and method of using the same The present invention involves a gel strip carrier module for a gel strip that reduces the handling of the gel strip and the hands-on-time during preparation of the gel strip for isoelectric focusing. The gel carrier module includes a gel strip chamber th... | 09/05/2000 |
| 5885431 | Microgels for use in medical diagnosis and methods of making and using same An electrophoresis microgel is formed in a gel holder. The gel holder comprises a top substrate, a bottom substrate and a spacer disposed between the top substrate and the bottom substrate. The spacer establishes a separation of from 25 to 250 microns bet... | 03/23/1999 |
| 5882495 | Electrophoresis system The present invention provides electrophoresis systems and methods for forming at least one gel therein and for conducting electrophoresis on the gel without removing the gel from the electrophoresis system. The systems of the present invention include an... | 03/16/1999 |
| 5865974 | Apparatus and method for electrophoresis A substantially closed cassette for conducting therein electrophoresis separation which includes a closed chamber, the chamber includes therein a body of gel, at least one ion source having a volume smaller than the volume of the gel for providing ions fo... | 02/02/1999 |
| 5851370 | Automated electrophoresis system and method Automated electrophoresis is performed by applying a cover plate to a substrate having a plurality of electrophoresis lanes, applying at least one sample to the plurality of electrophoresis lanes, electrophoresing the at least one sample, removing the cov... | 12/22/1998 |
| 5753095 | Plastic mold for electrophoresis gel An improved plastic mold for the polymerization of electrophoresis gels. The improved electrophoresis gel mold comprises non-conductive plastic film. The film is supported by a rigid plastic frame. The frame maintains the integrity of the electrophoresis ... | 05/19/1998 |
| 5618399 | Comb elements rotating in position to place selected slit arrays in the gel of an electrophoresis agarose gel tray, particularly as also serve as spacers between stacked trays A spacer-comb element including (i) a longitudinal central axis and (ii) three or more, preferably four, teeth arrays radially extending about the central axis and extending along a length thereof, serves to emplace arrayed slit apertures within flat shee... | 04/08/1997 |
| 5587061 | Device and method for biomolecule purification A novel device and method for biomolecule purification is provided as a handy tool for routine applications when both a high resolution and an easy manipulation are required. A sample is applied into a device and the different biomolecules are separated f... | 12/24/1996 |
| 5587062 | Sample collecting apparatus by gel electrophoresis An apparatus for collecting samples by gel electrophoresis has a base table, a cutting tool or an extractor disposed above the base table, a moving mechanism, a pattern detector and a control device. The base table is for placing thereon a gel in the form... | 12/24/1996 |
| 5582702 | Apparatus and method for electrophoresis A substantially closed cassette for conducting therein electrophoresis separation which includes a closed chamber, the chamber includes therein a body of gel, means for providing ions for driving the electrophoresis separation and electrodes for connectin... | 12/10/1996 |
| 5534121 | Preparative two dimensional gel electrophoresis system A preparative two dimensional gel electrophoresis system which serves as a single procedure for separation and isolation of preparative amounts of proteins from complex biological preparations. The system includes sized-up isoelectric focusing tube gels a... | 07/09/1996 |
| 5449446 | Multi-purpose electrophoresis apparatus The invention disclosed herein comprises a laboratory electrophoresis apparatus which overcomes many drawbacks of the previously known apparatus by combining a number of operations in the same unit, thereby eliminating the need for moving a gel between an... | 09/12/1995 |
| 5284559 | Preparative electrophoresis device and method A preparative electrophoresis device having a pair of spaced apart plates, a pre-cast electrophoretic gel between the plates, and a semipermeable membrane sealably connected to ends of the plates to define with the plates a collection channel for receivin... | 02/08/1994 |
| 5151165 | Methods and apparatuses for preparative electrophoresis The electrophoresis apparatus of the invention includes a semi-permeable element 6 which makes it possible to take advantage of the phenomenon of electro-endosmosis which is generated during electrophoresis, and outlet tube(s) 15 to transfer the products ... | 09/29/1992 |
| 4964961 | Elution method and device The present invention is directed to an apparatus for electro elution of components separated by preparative electrophoresis on a gel comprising a tapered tube divided by a porous disc into an upper section which is open at the top of the tapered tube and... | 10/23/1990 |
| 4913791 | Blot frame and method of handling A method and apparatus is disclosed for supporting and handling blot membranes during the course of blotting, analysis and storage.... | 04/03/1990 |
| 4911816 | Process for conducting electrophoresis and transfer An apparatus for carrying out horizontal gel electrophoresis for separation and subsequent vacuum-assisted transportation of macromolecules to a support membrane to facilitate detection. The entire procedure is conducted in one cartridge. A method for con... | 03/27/1990 |
| 4877510 | Apparatus for preparative gel electrophoresis Emerging solutes from a preparative gel electrophoresis column are drawn into a narrow transfer tube through a collar which fits over the column end and secures a porous plate and dialysis membrane to the column end. The collar is provided with a series o... | 10/31/1989 |
| 4707233 | Device for extraction of electrophoretic fractions A method and device for the preparative scale recovery of a protein or other charged macromolecule by electrophoretic separation of a mixture of such macromolecules. The device is adapted to be installed between the electrodes of an electrophoretic cell a... | 11/17/1987 |
| 4479861 | Method and apparatus for preparative gel electrophoresis A preparative gel electrophoresis apparatus comprises a first outer coolable cylinder, a second inner coolable cylinder within the outer cylinder, a compact column of separating material placed between the first and second cylinders and electrodes arrange... | 10/30/1984 |
| 4279724 | Preparative electrofocusing in flat bed granulated polysaccharide gels Methods are described for the generation of natural pH gradients in layers of granulated gels using mixtures of amphoteric or amphoteric non-amphoteric buffer reagents. Because of the favorable characteristics of these flat bed systems, high voltage gradi... | 07/21/1981 |
