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| Number | Title | Issue Date |
| 8173002 | Electro-blotting devices, systems, and kits, and methods for their use The invention provides a dry electroblotting system for dry blotting gels, in which the system includes an electroblotting transfer stack that comprises an analysis gel and a blotting membrane, an anode, a body of anodic gel matrix juxtaposed with the anode between ... | 05/08/2012 |
| 8075755 | Polymeric sorbent sheets as ion reservoirs for electroblotting Electroblotting for the transfer of electrophoretically separated species from a gel to a transfer membrane is performed in a semi-dry format with sheets of absorbent polyester or polyester/cellulose blend wetted with buffer solution in place of the traditional buff... | 12/13/2011 |
| 7435322 | Device and method for automatically analysing the constituents of an analyte The invention relates to a device and a method for automatically analysing the constituents of at least one analyte, especially by means of gel electrophoresis and/or isoelectric focussing, comprising at least one separating matrix, especially a gel. Each separating... | 10/14/2008 |
| 7384781 | Sensors for biomolecular detection and cell classification A sensor device is provided for detecting an analyte in a sample in which an analyte is bound to a detection reagent to form a bound complex. The device comprises (a) a sample (5) comprising an ionic analyte and a detection reagent in a conductive fluid, wher... | 06/10/2008 |
| 7250097 | Device for sequential protein transfer from a gel An apparatus and method for the sequential electroelution of biomolecules is described, the apparatus comprising a separation medium having an outlet, and a collector having at least a first receptacle and a second receptacle that can be sequentially brought into co... | 07/31/2007 |
| 6833060 | Electrophoresis gel support The present invention relates generally to the electrophoretic separation of biomolecules, including but not limited to proteins, peptides, DNA and RNA. The methods of this invention are particularly useful when applied to two-dimensional gel electrophoresis. ... | 12/21/2004 |
| 6638408 | Method and device for separation of charged molecules by solution isoelectric focusing The invention provides a novel solution isoelectric focusing device and method that can reproducibly fractionate charged molecules into well-defined pools. This approach can be applied to mixtures of charged molecules, such as eukaryotic proteome samples ... | 10/28/2003 |
| 6632339 | Method of identifying polypeptides Polypeptides which have been separated by gel electrophoresis can be identified by electroblotting them through a "sandwich" comprising in order: a) the separation gel; b) at least one hydrophilic membrane, e.g. of carboxyl-modified PVDF, on which... | 10/14/2003 |
| 6592734 | Semi-dry electroblotter A semi-dry electroblotter for transferring a gel after its electrophoresis onto a membrane enabling the electro-blotting process to be efficiently and effectively carried out within a short time, eliminating the shortcomings of the traditional technology,... | 07/15/2003 |
| 6193868 | Electrophoretic separating and blotting apparatus An electrophoretic separating and blotting apparatus, which includes a pressure block, two glass plates of different heights, a partition frame, a rack, a positioning unit, a cell, a blotting cassette, and two electrode plates. The component parts are alt... | 02/27/2001 |
| 5916429 | Direct blot electrophoresis apparatus and method In a horizontal gel, direct blot electrophoresis separation apparatus, device to remove gas dissolved in the buffer solution surrounding the anode at a location remote from the interface between the gel and the moving membrane, such as a gas evolution mem... | 06/29/1999 |
| 5840169 | Apparatus and process for electroelution of a gel containing charged macromolecules A process for electroelution of a gel containing charged macromolecules, such as proteins or polynucleotides, comprising the steps of providing a plurality of adjacent parallel chambers having a trapezoidal cross-section, placing a gel containing the char... | 11/24/1998 |
| 5635045 | Apparatus for, and a method of, electroelution isolation of biomolecules and recovering biomolecules after elution An apparatus for electroelution isolation of biomolecules and recovering biomolecules after elution including a tubular enclosure for engaging a piece of separating gel having a band of biomolecules. The enclosure is capped by a closure means having a pas... | 06/03/1997 |
| 5614361 | Method for identifying and characterizing organisms A method of characterizing an unknown organism species which comprises, determining the position of part or whole of evolutionarily conserved DNA sequences in DNA of the organism, relative to the position of restriction endonuclease cleavage sites in the ... | 03/25/1997 |
| 5595636 | Method for mass spectrometric analysis of samples from electrophoresis plates The invention relates to the mass spectrometric analysis of separated substance samples on so-called 2-D-gel electrophoresis plates, used particularly for protein determination, with ionization of the substance samples by MALDI. The molecules of the subst... | 01/21/1997 |
| 5514256 | Apparatus for improved DNA sequencing This invention is a means for the rapid sequencing of DNA samples. More specifically, it consists of a new design direct blotting electrophoresis unit. The DNA sequence is deposited on a membrane attached to a rotating drum. Initial data compaction is fac... | 05/07/1996 |
| 5480803 | Apparatus for treating analytes An apparatus includes an enclosed chamber in which a motor-driven cylinder is mounted for rotation about a horizontal axis. The lower half of the cylinder is disposed in a trough. A blot can be attached, analyte side outward, to the surface of the cylinde... | 01/02/1996 |
| 5474663 | Bowed framed membrane, processes for the preparation thereof, and uses therefor A bowed framed membrane is disclosed for use in automated direct blot electrophoresis and subsequent membrane process steps to develop a chemiluminescent image of the resultant blot of selected fragments and to detect that image. A frame made from a thin ... | 12/12/1995 |
| 5449446 | Multi-purpose electrophoresis apparatus The invention disclosed herein comprises a laboratory electrophoresis apparatus which overcomes many drawbacks of the previously known apparatus by combining a number of operations in the same unit, thereby eliminating the need for moving a gel between an... | 09/12/1995 |
| 5445723 | Blotting apparatus A blotting apparatus for transferring electrophoretically separated material from electrophoresis gels in a transfer stack. The device includes a resilient anode surface for more consistent transfer of DNA from DNA sequencing gels in the transfer stack to... | 08/29/1995 |
| 5439573 | Concentrating electroelutinon apparatus An electrophoretic gel elutor and concentrator includes a semi-permeable collecting membrane having a continuously diminishing cross-section terminating in an apex, and a supporting frame of matching configuration. This apparatus is useful in electrophore... | 08/08/1995 |
| 5415758 | Method and apparatus for electro-elution of biological molecules The invention includes methods for electro-elution of a biological molecule from a biological sample matrix, the methods including electro-eluting a negatively charged molecule from each of plural individual sample matrices via corresponding plural electr... | 05/16/1995 |
| 5395498 | Method for separating biological macromolecules and means therfor Macromolecules from a sample are electrophoresed and the obtained electrophoretogram is contacted with a planar matrix of magnetic particles. The magnetic particles having binding specificity to one or more specific species of biological macromolecules, w... | 03/07/1995 |
| 5350502 | Apparatus for fluid treatment of framed membranes A disclosure is made of automatic apparatus for processing transfer membranes to which a blot pattern of molecular fragments has been bound so that the pattern may be optically visualized. The apparatus is characterized by at least one open processing cel... | 09/27/1994 |
| 5340449 | Apparatus for electroelution This invention involves the elution of macromolecules such as proteins, deoxyribonucleic acid(DNA), ribonucleic acid(RNA) from solid phase matrix such as polyacrylamide, agarose and membranes such as polyvinyl difluoride (PVDF) in an electric field. The e... | 08/23/1994 |
| 5306468 | Apparatus for the handling of electrophoretic transfer membranes and for the chemiluminescent detection of blots contained thereon Improved apparatus for the handling and detecting of an electrophoretic transfer membrane is disclosed herein, the improvement comprising guide apparatus designed to accommodate the transfer membrane, a pressure head positioned relative to the guide appar... | 04/26/1994 |
| 5279721 | Apparatus and method for an automated electrophoresis system An automated electrophoresis and transfer apparatus for separating macromolecules in accordance with their molecular weight and transferring the same to a transfer membrane includes a housing having a perforated intermediate horizontal partition defining ... | 01/18/1994 |
| 5275710 | Gel electrophoresis system including optical stage, sample applicator and sample retriever An electrophoretic system is provided which allows for carrying out electrophoresis while monitoring and regulating the temperature and the electrical field gradient in the gel. In addition, photometric monitoring, including use of an optical stage, is pr... | 01/04/1994 |
| 5234559 | Apparatus for direct blotting and automated electrophoresis, transfer and detection and processes utilizing the apparatus thereof A separation and direct blot transfer module useful in gel electrophoresis is disclosed in which a transfer membrane stabilized by a frame is moved substantially orthogonally relative to the plane of the separation gel while in minimal contact with the en... | 08/10/1993 |
| 5217592 | Electrophoresis and vacuum molecular transfer apparatus An apparatus which includes the combination of a submarine gel tank, for the electrophoresic separation of, for example, nucleic acid molecules on agarose slab gels, with a vacuum applying means which transfers the separated molecules from the gel, withou... | 06/08/1993 |
| 5151189 | Cationic charge modified microporous membrane Cationic charge modified microporous hydrophilic membranes are provided, as well as preparation of the same by post-treatment. Typically, as an illustration, a microporous hydrophilic membrane substrate which contains non-leachable polymeric additive havi... | 09/29/1992 |
| 5112459 | Apparatus and method for transfer of macromolecules An apparatus and method for the transfer of macromolecules from a source medium to a transfer medium employ positive pressure to urge a sample from the source medium to the transfer medium. The source and transfer media are disposed in adjacent relation, ... | 05/12/1992 |
| 5102524 | Multiple electrophoresis device for the controlled migration of macromolecules through rectangular gel plates A multiple electrophoresis method and device are disclosed for the controlled migration of macromolecules in gel plates stacked in a direction perpendicular to their plane, at least one series of electrodes (20) disposed at the intersections of two series... | 04/07/1992 |
| 5013420 | Gel electrophoresis/electro-blot apparatus A gel electrophoresis/electro-blot transfer apparatus comprising a buffer tank having a upper and lower section adapted to maintain a buffer solution, a support frame for supporting a gel slab, a first member for securing the gel slab in a substantially v... | 05/07/1991 |
| 4994166 | Single apparatus for slab gel electrophoresis and blotting Electrophoretic separation in a slab gel and blotting of the resulting zone pattern onto a membrane are both performed in a single tank cell which contains separation electrodes along opposing vertical walls and blotting electrodes horizontally arranged a... | 02/19/1991 |
| 4913791 | Blot frame and method of handling A method and apparatus is disclosed for supporting and handling blot membranes during the course of blotting, analysis and storage.... | 04/03/1990 |
| 4911816 | Process for conducting electrophoresis and transfer An apparatus for carrying out horizontal gel electrophoresis for separation and subsequent vacuum-assisted transportation of macromolecules to a support membrane to facilitate detection. The entire procedure is conducted in one cartridge. A method for con... | 03/27/1990 |
| 4889606 | Electrophoresis and transfer for A method and apparatus for use in biological testing. The apparatus comprises electrophoresis apparatus comprising a tank (1) the interior of which is formed with a raised portion (5) which splits the tank into the two compartments (6,7) containing electr... | 12/26/1989 |
| 4849078 | Process for conducting electrophoresis and transfer An apparatus for carrying out horizontal gel electrophoresis for separation and subsequent vacuum-assisted transportation of macromolecules to a support membrane to facilitate detection. The entire procedure is conducted in one cartridge. A method for con... | 07/18/1989 |
| 4840714 | Electroblotting technique for transferring specimens from a polyacrylamide electrophoresis or like gel onto a membrane An apparatus especially suitable for transferring a particular specimen from a polyacrylamide electrophoresis or like gel onto a support sheet by means of electroblotting is disclosed herein along with its method of operation. This apparatus utilizes a pa... | 06/20/1989 |
