Quotables
"There is no reason anyone would want a computer in their home."
Ken Olsen, chairman and founder of Digital Equipment Corporation ; 1977
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7425254 | Fractionation of macro-molecules using asymmetric pulsed field electrophoresis A method and apparatus for fractionation of charged macro-molecules such as DNA is provided. DNA solution is loaded into a matrix including an array of obstacles. An alternating electric field having two different fields at different orientations is applied. The alt... | 09/16/2008 |
| 7282127 | Microcapillary devices using high dielectric constant materials and related methods A microcapillary device includes a microcapillary tube. An anode is positioned at a first end of the microcapillary tube. A cathode is positioned at a second end of said microcapillary tube. A plurality of electric field reducing components are spaced apart along a ... | 10/16/2007 |
| 7217352 | Capillary electrophoresis device An electrophoresis device is disclosed that is capable of reducing waves occurring in a fluid in which the capillary tips of a capillary assay are immersed. A plurality of partition plate members can be provided in a container containing the fluid to divide the surf... | 05/15/2007 |
| 7189316 | Pulsed field electrophoresis chambers, accessories and method of utilization for separation of DNA molecules Methods of use, accessories and chambers, optimal for performing Pulsed Field Gel Electrophoresis (PFGE) of DNA molecules in ‘Contour Clamped Homogeneous Electric Field’ (CHEF) and ‘Transversal Alternating Field Electrophoresis’ (TAFE) systems, are provided ... | 03/13/2007 |
| 7172896 | Integrated portable biological detection system We have performed separation of bacterial and cancer cells from peripheral human blood in microfabricated electronic chips by dielectrophoresis. The isolated cells were examined by staining the nuclei with fluorescent dye followed by laser induced fluorescence imagi... | 02/06/2007 |
| 7125478 | Microscale electrophoresis devices for biomolecule separation and detection The present invention relates to microfabrication and utilization of microscale electrophoresis devices as well as the separation and detection of biomolecules in microscale electrophoresis devices. The device of the present invention utilizes novel fabrication and ... | 10/24/2006 |
| 7112266 | Multi channel capillary electrophoresis device and method Embodiments of a device and method are described which provide for control over the distortion of a sample zone upon exiting an electrophoresis separation channel. According to the teachings herein (i) the downstream regions of the channels, near the outlet ends, an... | 09/26/2006 |
| 7087148 | Binding acceleration techniques for the detection of analytes The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either dire... | 08/08/2006 |
| 6974528 | High performance wide bore electrophoresis Methods, apparatus and systems are provided for efficient separation of various small and large molecules, especially biomolecules such as proteins, nucleic acids and polysaccharides. In particular, an electrophoresis apparatus is employed in a wide bore electrophor... | 12/13/2005 |
| 6969449 | Multi-well plate and electrode assemblies for ion channel assays Plate and electrode assemblies include configurations allowing for relatively uniform electric field production. The electrodes may comprise strips of conductive material plated onto the bottom surface of sample wells or they may comprise plate electrodes extending ... | 11/29/2005 |
| 6913679 | Apparatus and methods for high resolution separation of sample components on microfabricated channel devices Sample component separation apparatus and methods are described. An exemplary sample component separation apparatus includes a separation channel having a turn portion configured to reduce band-broadening caused by passage of a sample through the turn portion. To re... | 07/05/2005 |
| 6881317 | Fractionation of macro-molecules using asymmetric pulsed field electrophoresis A method and apparatus for fractionation of charged macro-molecules such as DNA is provided. DNA solution is loaded into a matrix including an array of obstacles. An alternating electric field having two different fields at different orientations is applied. The alt... | 04/19/2005 |
| 6866759 | Stepped electrophoresis for movement and concentration of DNA A fluidic channel patterned with a series of thin-film electrodes makes it possible to move and concentrate DNA in a fluid passing through the fluidic channel. The DNA has an inherent negative charge and by applying a voltage between adjacent electrodes the DNA is c... | 03/15/2005 |
| 6837977 | Capillary electrophoresis method for screening for affinity ligands using a detectable competitive ligand The invention relates to a capillary electrophoresis-based method of screening complex materials for any unidentified affinity ligand that binds to a target of interest. The method subjects a plug of a mixture of the target and a complex material sample, and a separ... | 01/04/2005 |
| 6524866 | Capillary electrophoretic method to detect target-binding ligands and to determine their relative affinities The invention relates to capillary electrophoretic methods for detecting ligands or hit compounds that can bind to a selected target at or above a selected binding strength. The method allows one to rank various ligands based on their relative affinity, i... | 02/25/2003 |
| 6113767 | Electrophoresis sequencing apparatus A compact, low cost, automated electrophoresis apparatus provides for the optical detection of multiple DNA samples. A substantially cylindrical gel cartridge houses multiple sample lanes that are sealed on the outer periphery by a shrink tube, which allo... | 09/05/2000 |
| 6103084 | Apparatus for electroporation An apparatus for electroporation stores a level of charge, specified by a user, on a capacitor, which is delivered to a cuvette through an optically isolated high voltage switch. The capacitor is charged through a charging system, including a current mode... | 08/15/2000 |
| 6068753 | Automatic electrophoresis apparatus with fluorescent and visible scanning An apparatus for electrophoresing a sample and for thereafter either scanning in the visible mode or the fluorescent mode, under control of a central processor, to provide scanning densitometry of the electrophoresed sample, and with the fluorescent mode ... | 05/30/2000 |
| 6007689 | Apparatus for preparing gels for use in electrophoretic separations and similar applications An apparatus for the rapid preparation of electrophoresis gels comprises: (a) a housing; (b) a support fixture removably disposed within the housing and adapted to receive a gel holder having an internal gel compartment, the support fixture being optional... | 12/28/1999 |
| 5949899 | Apparatus for measuring and analyzing electrophoresis images A system for measuring and analyzing an image of a gel electrophoresis, includes measuring apparatus and a processor. The measuring apparatus includes a frame mountable in a fixed location relative to the image, including a bar extending along a first axi... | 09/07/1999 |
| 5846394 | Method and apparatus for carrying out electrophoresis in fractal fields A method and apparatus for carrying out electrophoretic separation is provided which imparts a fractal field component to the particles themselves or to the medium in which the particles are to be separated which, in combination with a steady field compon... | 12/08/1998 |
| 5776767 | Virtual DNA sequencer A virtual DNA sequencer combines a plurality of individual DNA sequencers. Samples of DNA or other nucleic acid from subjects are prepared and allocated in real time to particular lanes or sets of lanes in electrophoresis plates of the individual sequence... | 07/07/1998 |
| 5650055 | Electrophoresis separation method and apparatus using barrier separation and polarity reversing The method and apparatus for preparative electrophoresis is especially useful for proteins. An electrophoretic potential with an initial polarity is applied across an electrophoretic medium (13) to induce at least two species of macromolecules (1,2) in a ... | 07/22/1997 |
| 5616227 | Method for extending the life of electrophoretic gels A method for extending the useful lifetime and improving the reproducibility of electrophoresis gels, particularly gel-filled capillaries. The polarity of the applied electric field imposed across the gel is periodically reversed between one or more elect... | 04/01/1997 |
| 5587062 | Sample collecting apparatus by gel electrophoresis An apparatus for collecting samples by gel electrophoresis has a base table, a cutting tool or an extractor disposed above the base table, a moving mechanism, a pattern detector and a control device. The base table is for placing thereon a gel in the form... | 12/24/1996 |
| 5549796 | Electrophoresis using contour-clamped electric fields A gel electrophoresis method and apparatus is described in which the shape and orientation of the electric field is controlled by contour clamping. Electrodes are arranged around a closed contour. Two or more electrodes, the driving electrodes, are clampe... | 08/27/1996 |
| 5538613 | Electrophoresis analyzer An apparatus for detecting fluorescently-labeled molecules moving in an electrophoretic separation medium. The apparatus utilizes a scanning detection system in which multiple fluorophores are efficiently and simultaneously detected using dichroic mirrors... | 07/23/1996 |
| 5534125 | DNA sequencing To sequence DNA, DNA samples marked with flourscent infrared dye are applied at a plurality of locations for electrophoresing in a plurality of channels through a gel electrophoresis slab. The channels are scanned with a laser and a sensor, that include a... | 07/09/1996 |
| 5518604 | Buffer shaping device Electrophoresis apparatus with a gel support configured and arranged to hold a gel, a buffer chamber configured and arranged to hold a buffer, with the buffer contacting each end of the gel, and a buffer shaper configured to be positioned near the gel sup... | 05/21/1996 |
| 5419825 | Base sequencing apparatus An on-line system base sequencing apparatus wherein calibration coefficients for time bases of respective electrophoresis lanes are evaluated from differences between positions of signals already outputted in a range causing no sequence inversion and posi... | 05/30/1995 |
| 5360523 | DNA sequencing To sequence DNA, DNA samples marked with fluorescent infrared dye are applied at a plurality of locations for electrophoresing in a plurality of channels through a gel electrophoresis slab. The channels are scanned with a laser and a sensor, that include ... | 11/01/1994 |
| 5342497 | Electrophoresis system The invention provides an electrophoresis system which separates charged chemical substances by means of applying an electrical potential across a buffer solution which includes those chemical substances. The system of the invention includes a power suppl... | 08/30/1994 |
| 5279721 | Apparatus and method for an automated electrophoresis system An automated electrophoresis and transfer apparatus for separating macromolecules in accordance with their molecular weight and transferring the same to a transfer membrane includes a housing having a perforated intermediate horizontal partition defining ... | 01/18/1994 |
| 5217593 | Nucleic acid purification system and method A process for the purification of DNA and the like comprises a housing having walls forming a reservoir having a chamber for containing a buffer solution, means for circulating a buffer through the reservoir, a disposable cassette within said chamber havi... | 06/08/1993 |
| 5194133 | Sensor devices A sensor device for the analysis of a sample fluid comprises a substrate in a surface of which an elongate channel is micromachined. The channel contains a material, such as a starch, agarose, alginate, carrageenin or polyacrylic polymer gel, with a biolo... | 03/16/1993 |
| 5190632 | Multi-colored electrophoresis pattern reading system The multi-colored electrophoresis pattern reading system compares the patterns of electrophoresis without a warp to be caused upon electrophoresis by reading the patterns of electrophoresis which is carried out concurrently for plural samples and by label... | 03/02/1993 |
| 5185071 | Programmable electrophoresis with integrated and multiplexed control A user programmable device for horizontal gel eletrophoresis is provided. This device can both accurately and programmably control: (a) the angle between electrical field and gel by use of a rotatable gel bed, (b) magnitude of the electrical field, and (c... | 02/09/1993 |
| 5167790 | Field-inversion gel electrophoresis A method and apparatus for gel electrophoresis which employs periodic inversion of the electric field essentially in one dimension, denoted as field-inversion gel electrophoresis (FIGE), results in net migration by using a longer time or higher voltage in... | 12/01/1992 |
| 5165898 | Electrophoresis using contour-clamped electric fields A gel electrophoresis method and apparatus is described in which the shape and orientation of the electric field is controlled by contour clamping. Electrodes are arranged around a closed contour. Two or more electrodes, the driving electrodes, are clampe... | 11/24/1992 |
| 5147522 | Automatic electrophoresis apparatus and method Apparatus adapted to provide electrophoresis current sheets in opposite longitudinal directions of an electrophoresis plate is disclosed. The apparatus is designed to work with an existing automatic electrophoresis machine which performs all electrophores... | 09/15/1992 |
