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| Number | Title | Issue Date |
| 8101137 | Analysis instrument An analysis instrument for processing a microfluidic device, having sample storage means, a microfluidic device holder, sample loading means for loading sample into a microfluidic device disposed in the holder, processing means for enabling a reaction in a microflui... | 01/24/2012 |
| 8029743 | Microfluidic device with vertical injection aperture A microfluidic device with a vertical injection aperture is provided. The microfluidic device comprises a separation channel, an injection aperture disposed adjacent to and in fluid communication with the separation channel. The microfluidic device further comprises... | 10/04/2011 |
| 7846315 | Integrated bio-analysis and sample preparation system An integrated bio-analysis system incorporates built-in sample preparation capabilities. In one aspect of the present invention, a bio-analysis instrument is provided with a built-in sample preparation device based on PCR (or thermal cycling block/module). In one em... | 12/07/2010 |
| 7811436 | Electrophoresis apparatus having an outlet passage An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises a relatively large-bore transport capillary which intersects with a ... | 10/12/2010 |
| 7790008 | Electrophoresis chip and electrophoresis unit having the same In order to provide a high-performance electrophoresis chip and an electrophoresis unit having the same that can restrain the diffusion of sample at an intersection between the electrophoresis groove and the sample introduction groove and prevent decrease in contras... | 09/07/2010 |
| 7655125 | Electrophoresis apparatus For automating the operation of an electrophoresis apparatus and improving the throughput, the present electrophoresis apparatus has two platens capable of controlling temperature of electrophoresis plates placed thereon, a loading medium charging unit for sending a... | 02/02/2010 |
| 7439075 | Method and device for withdrawing suspended microparticles from a fluidic microsystem A method of discharging a fluid flow with suspended microparticles from a fluidic microsystem (10) is described, whereby the fluid flow converges with at least one output flow to form a discharge flow at the end of a discharge channel (14) of the micro... | 10/21/2008 |
| 7438793 | Capillary array having load header A multi-capillary array which can be used for a multi-capillary electrophoresis apparatus to effectively disperse the heat generated within a load header. In a load header of the capillary array used for the multi-capillary electrophoresis, an insulated holder, a co... | 10/21/2008 |
| 7435322 | Device and method for automatically analysing the constituents of an analyte The invention relates to a device and a method for automatically analysing the constituents of at least one analyte, especially by means of gel electrophoresis and/or isoelectric focussing, comprising at least one separating matrix, especially a gel. Each separating... | 10/14/2008 |
| 7422672 | Capillary array apparatus, method of manufacturing the same, and electrophoresis analysis method An electrophoresis analysis method and apparatus capable of maintaining high reliability upon a repeated use of the same gel. A heat transfer medium selected from the group consisting of solids, liquids and gels is filled in substantially all of the gaps between the... | 09/09/2008 |
| 7417418 | Thin film sensor An electrically operated, particle detecting, or characterizing, sensor structured as a thin film multilayer sandwich. Three or more electrodes are deposited onto thin layers of film, and stacked to form the sandwich. A representative stacking arrangement provides a... | 08/26/2008 |
| 7396444 | Device to operate a laboratory microchip In a device to operate and handle a laboratory microchip to chemically process or analyze substances, the microchip is on a chip holder (41) that is part of a first assembly (42). The first assembly (42) also has an optical device (43) fo... | 07/08/2008 |
| 7390390 | Capillary array electrophoretic device and auto sampler used for the device A capillary array electrophoretic device capable of securing a sample plate array and a buffer container three dimensionally on a tray of an autosampler. A tray (700) is provided with a guide groove (701) and a stopper (702) corresponding to gui... | 06/24/2008 |
| 7387765 | Microfluidic chip system integrated with nano-electrospray interface and method using thereof The present invention provides an integrated microfluidic electrospray chip system and analytical method thereof, characterized in which the proteinase reaction, solid-phase extraction mechanism, electrophoresis and mass spectrometry are integrated into one system. ... | 06/17/2008 |
| 7371310 | Apparatus for producing a thin sample band in a microchannel system The present invention improves the performance of microchannel systems for chemical and biological synthesis and analysis by providing a method and apparatus for producing a thin band of a species sample. Thin sample bands improve the resolution of microchannel sepa... | 05/13/2008 |
| 7364705 | Microfabricated structures for facilitating fluid introduction into microfluidic devices Fluid introduction is facilitated through the use of a port which extends entirely through a microfluidic substrate. Capillary forces can be used to retain the fluid within the port, and a series of samples or other fluids may be introduced through a single port by ... | 04/29/2008 |
| 7364703 | Microfabricated structures for facilitating fluid introduction into microfluidic devices Fluid introduction is facilitated through the use of a port which extends entirely through a microfluidic substrate. Capillary forces can be used to retain the fluid within the port, and a series of samples or other fluids may be introduced through a single port by ... | 04/29/2008 |
| 7364704 | Microfabricated structures for facilitating fluid introduction into microfluidic devices Fluid introduction is facilitated through the use of a port which extends entirely through a microfluidic substrate. Capillary forces can be used to retain the fluid within the port, and a series of samples or other fluids may be introduced through a single port by ... | 04/29/2008 |
| 7364915 | Microfabricated structures for facilitating fluid introduction into microfluidic devices Fluid introduction is facilitated through the use of a port which extends entirely through a microfluidic substrate. Capillary forces can be used to retain the fluid within the port, and a series of samples or other fluids may be introduced through a single port by ... | 04/29/2008 |
| 7364916 | Microfabricated structures for facilitating fluid introduction into microfluidic devices Fluid introduction is facilitated through the use of a port which extends entirely through a microfluidic substrate. Capillary forces can be used to retain the fluid within the port, and a series of samples or other fluids may be introduced through a single port by ... | 04/29/2008 |
| 7364706 | Microfabricated structures for facilitating fluid introduction into microfluidic devices Fluid introduction is facilitated through the use of a port which extends entirely through a microfluidic substrate. Capillary forces can be used to retain the fluid within the port, and a series of samples or other fluids may be introduced through a single port by ... | 04/29/2008 |
| 7361259 | Capillary array and electrophoresis apparatus, and method A capillary electrophoresis device including a capillary array, and a method of manufacturing the capillary array, are provided. During the manufacture of the capillary array, a plurality of capillaries are arranged in a substantially parallel arrangement and are fi... | 04/22/2008 |
| 7347617 | Mixing in microfluidic devices Mixing of liquids in a microfluidic device is accomplished by dispensing the liquids into a first chamber to produce combined liquid. The liquids are thereafter discharged through at least one capillary from the first chamber into a second chamber for complete mixin... | 03/25/2008 |
| 7344628 | Capillary electrophoresis-electrochemical detection microchip device and supporting circuits The present invention is a capillary electrophoresis device, comprising a substrate; a first channel in the substrate, and having a buffer arm and a detection arm; a second channel in the substrate intersecting the first channel, and having a sample arm and a waste ... | 03/18/2008 |
| 7341652 | Stationary capillary electrophoresis system A system and method for capillary electrophoresis are provided for analyzing a macromolecule prepared from a complex liquid mixture. In particular applications, methods and apparatus are provided for separating and analyzing a solution containing a denatured macromo... | 03/11/2008 |
| 7338584 | Electrophoresis apparatus An electrophoresis apparatus 1 has an introducing passage 11 for allowing a sample to move from one end of the introducing passage 11 toward the other end thereof, and an analyzing passage 10, formed so as to cross the introducing passage... | 03/04/2008 |
| 7334630 | Closed-loop microchannel cooling system Apparatus and methods according to the present invention utilize micropumps that are capable of generating high pressure and flow without moving mechanical parts and the associated generation of unacceptable electrical and acoustic noise, as well as the associated r... | 02/26/2008 |
| 7323140 | Moving microdroplets in a microfluidic device The present invention relates to a system and method for moving samples, such as fluid, within a microfluidic system using a plurality of gas actuators for applying pressure at different locations within the microfluidic. The system includes a substrate which forms ... | 01/29/2008 |
| 7316543 | Electroosmotic micropump with planar features An electroosmotic micropump having a plurality of thin, closely-spaced, approximately planar, transversel aligned partitions formed in or on a substrate, among which electroosmotic flow (EOF) is generated. Electrodes are located within enclosed inlet and outlet mani... | 01/08/2008 |
| 7312611 | Apparatus and method for trapping bead based reagents within microfluidic analysis systems The present invention provides an on-chip packed reactor bed design that allows for an effective exchange of packing materials such as beads at a miniaturized level. In accordance with the present invention, there is provided a method of concentrating an analyte wit... | 12/25/2007 |
| 7312029 | Method of combing an elongated molecule Elongated molecules are stretched across a substrate by controlled fluid flow. ... | 12/25/2007 |
| 7294503 | Microfabricated crossflow devices and methods A microfluidic device for analyzing and/or sorting biological materials (e.g., molecules such as polynucleotides and polypeptides, including proteins and enzymes; viruses and cells) and methods for its use are provided. The device and methods of the invention are us... | 11/13/2007 |
| 7289105 | Real motion detection sampling and recording for tracking and writing instruments using electrically-active viscous material and thin films The present invention details a system for tracking writing motions internally to the pen (or other instrument) and communicating such motions to a general or specific purposes computer systems. In a preferred embodiment the present invention uses multiple tubes wit... | 10/30/2007 |
| 7270730 | High-throughput electrophysiological measurement system Systems, including apparatus and methods, for performing electrophysiological measurements on membranous samples, including living cells, isolated cell fragments (such as organelles), and/or artificial membranes (such as vesicles). The apparatus may include a high-t... | 09/18/2007 |
| 7270786 | Methods and systems for processing microfluidic samples of particle containing fluids The present invention relates to a microfluidic system for processing a cell-containing liquid. The system includes a microfabricated substrate having an enrichment channel to prepare an enriched cell sample from the cell-containing liquid. A flow through member is ... | 09/18/2007 |
| 7261801 | Method for analyzing a sample from a process with on-line capillary electrophoresis apparatus and capillary electrophoresis apparatus Disclosed is a method and apparatus by which a sample can be taken from a process and be analyzed on-line by means of a capillary electrophoresis apparatus. On the feed side of the capillary electrophoresis unit (13) the sample is continuously collected via a... | 08/28/2007 |
| 7258776 | Capillary array assembly for loading samples from a device, and method A capillary array assembly is provided that can be used to inject samples into an electrophoresis device. The capillary array assembly can include an injection end that can be arranged to interface with output wells of a fluid processing device, for example, a micro... | 08/21/2007 |
| 7238268 | Microfluidic devices for the controlled manipulation of small volumes A method for conducting a broad range of biochemical analyses or manipulations on a series of nano- to subnanoliter reaction volumes and an apparatus for carrying out the same are disclosed. The invention is implemented on a fluidic microchip to provide high serial ... | 07/03/2007 |
| 7235163 | Loading features for channel array Apparatus and method for loading a channel device for electrophoretic separation including cilia which can be deflected into wells of a multi-well tray. ... | 06/26/2007 |
| 7231839 | Electroosmotic micropumps with applications to fluid dispensing and field sampling Apparatus and methods according to the present invention preferably utilize electroosmotic pumps in fluid handling and field sampling applications. The electroosmotic pumps used in these applications are capable of generating high pressure and flow without moving me... | 06/19/2007 |
