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| Number | Title | Issue Date |
| 8252162 | Capillary electrophoresis apparatus The invention provides a capillary electrophoresis apparatus which can improve the operability and measuring speed. According to the invention, a sensor for identifying the type of sample containers is fixed at the position away from a capillary anode electrode. The... | 08/28/2012 |
| 8246805 | Micro-fluidic chip and flow sending method in micro-fluidic chip Disclosed herein is a micro-fluidic chip including a hollow area into which a charged droplet is introduced, and an electrode configured to be provided toward the hollow area. Movement direction of a droplet in the hollow area is controlled based on electric force a... | 08/21/2012 |
| 8187442 | Microchip processing method and apparatus The processing apparatus for microchips, each at least having a main flow path performing migration of a sample for analysis inside a sheet-like member, comprises a holding part holding microchips so that the multiple main flow paths are provided; a pretreatment par... | 05/29/2012 |
| 8052856 | Support for capillaries, case for constraining capillaries including the same A support for capillaries comprises a ceramic member having a flat surface area on which the capillaries are to be aligned. The flat surface area has a flatness of not more than 0.02 mm and has a mean spacing of waviness motifs (AW) of not more than 100 μm. ... | 11/08/2011 |
| 8012430 | Methods for producing microchannel chips, microchannel chips, methods for separating biomolecules using the microchannel chips, and electrophoretic apparatus having the microchannel chips The methods for producing microchannel chips of the present invention comprise the steps of shielding substrate surfaces on which groove-like channels have been formed, using a mask that exposes the channels, and then forming polymer membranes on the exposed surface... | 09/06/2011 |
| 7981267 | Capillary electrophoresis device An object of the present invention is to prevent a variation in heat dissipating effect of a capillary between a holder part and an oven, to improve reproducibility of migration time, and to reduce a variation of migration time among capillaries in a single electrop... | 07/19/2011 |
| 7887690 | DNA separation device, DNA separation method, and ligand DNA A ligand DNA including a probe portion having a sequence that is complementary to a target DNA to be detected in a sample DNA, and a probe portion having a base sequence that is complementary to a base sequence of a marker DNA 2 in a conjugate DNA 10 i... | 02/15/2011 |
| 7883613 | Capillary electrophoresis apparatus The present invention provides a capillary electrophoresis apparatus in which a capillary is easily attached to and detached from a migration medium filling unit without mixing impurities into the capillary. Mixture of impurities such as dust is also prevented when ... | 02/08/2011 |
| 7727371 | Electrode apparatus for use with a microfluidic device An electrode alignment apparatus may be used with a microfluidic device for accurate and repeatable alignment of electrode pins with reservoirs on the microfluidic device. The apparatus includes a base unit and an electrode block assembly that are moveable with resp... | 06/01/2010 |
| 7713394 | Electrophoresis apparatus using capillary array and sample plate assembly used therefor A sample plate assembly for an electrophoresis apparatus including a tray at a sample supply portion of a capillary array, an adapter for the tray, a sample plate mounted on the adapter, a septer mounted on the sample plate and a septer holder mounted on the septer.... | 05/11/2010 |
| 7708874 | Electrophoresis apparatus An electrophoresis apparatus having a plate on which channels are formed, a tray on which the plate is to be set, a tray driving unit for rotary driving the tray on which the plate is set, a voltage application unit for applying voltage to a buffer agent in the chan... | 05/04/2010 |
| 7662269 | Capillary electrophoretic instrument and capillary array assembly The troublesomeness during the setting of a plurality of capillaries is eliminated by composing pairs of electrodes, which are electrically connected to the common electrode, and capillaries. By bringing electrodes installed in the vicinity of each capillary dispose... | 02/16/2010 |
| 7658830 | Capillary array and electrophoresis apparatus, and methods A capillary array capable of being easily mounted on an electrophoresis apparatus without damaging the capillaries. The capillary array can include a plurality of capillaries that can be fixed via hollow electrodes on a load header in a matrix arrangement. The load ... | 02/09/2010 |
| 7651600 | Electrokinetic concentration device and methods of use thereof The present invention provides a device and methods of use thereof in concentrating a species of interest and/or controlling liquid flow in a device. The methods, inter-alia, make use of a device comprising microchannels, which are linked to nanochannels, whereby in... | 01/26/2010 |
| 7641780 | Two-dimensional microfluidics for protein separations and gene analysis The invention provides a microfluidic apparatus for performing 2-D biomolecular separations. The microfluidic 2-D device may include first and second planar substrates which include at least a first dimension microchannel extending in a first direction and an array ... | 01/05/2010 |
| 7638025 | Fluid handling apparatus When a first liquid fed into a first flow passage 6 moves therein toward a connecting portion 10 due to capillarity, gas in the first flow passage 6 is pushed by the moving first liquid to be exhausted to the external environment via a third flo... | 12/29/2009 |
| 7632389 | Open tube suitable for separation purposes comprising covalently bonded zwitterionic betaine groups A novel open tube with a zwitterionic betaine polymer layer can be prepared by initiated grafting polymerization. This open tube can be used for separating inorganic anions, peptides and proteins. A capillary electrophoresis method and a capillary chromatography met... | 12/15/2009 |
| 7618524 | Polymeric salt bridges for conducting electric current in microfluidic devices A “cast-in-place” monolithic microporous polymer salt bridge for conducting electrical current in microfluidic devices, and methods for manufacture thereof is disclosed. Polymeric salt bridges are formed in place in capillaries or microchannels. Formulations are... | 11/17/2009 |
| 7601252 | Multi-capillary electrophoresis apparatus Scattering on analysis in a multi-capillary electrophoresis apparatus is suppressed. The multi-capillary electrophoresis apparatus has a multi-capillary array that has a sample and a separation medium for separating a sample charged therein, and has a sampling secti... | 10/13/2009 |
| 7594986 | Apparatus for capillary electrophoresis comprising polyelectrolyte multilayers An apparatus and method for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage defined by passage walls comprising fused silica. The poly... | 09/29/2009 |
| 7591936 | Microfluidic device wherein the liquid/fluid interface is stabilized The microfluidic device comprises at least one microchannel bounded by a bottom wall, side walls and a top wall and which is designed to contain at least one liquid and at least one fluid non-miscible with the liquid. The microfluidic device comprises means for stab... | 09/22/2009 |
| 7588671 | Microfluidic treatment method and device The present invention relates to a microchip apparatus using liquids. More specifically, the invention provides a liquid mixing apparatus comprising at least two microchannels for introducing liquids and a mixing microchannel that connects to the at least two liquid... | 09/15/2009 |
| 7540949 | Capillary array electrophoresis apparatus and method of separating and analyzing specimen At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays having different length. Thereby, a selected capillary array constitute... | 06/02/2009 |
| 7534335 | Multiplexed, absorbance-based capillary electrophoresis system and method A multiplexed, absorbance-based electrophoresis system for analyzing multiple samples simultaneously without use of a mask or slit comprising a light source, a planar array of capillary tubes and a detector positioned off-axis with the light source and positioned on... | 05/19/2009 |
| 7524409 | Method and system for electrokinetic, preparative sample separation in high-surface-area separation channels with non-convex cross sections Embodiments of the present invention employ complexly shaped, high-surface-area channels for separation and purification of molecules, including important biopolymers such as proteins, glycoproteins, polysaccharides, and other molecular components of living cells. T... | 04/28/2009 |
| 7491305 | High density electrophoresis device and method The present invention provides, in one aspect, an apparatus or electrophoretic separation of analytes. In one aspect, the apparatus comprises a disc-shaped substrate defining (1) a central reservoir region, (2) a plurality of electrophoretic channels in fluid commun... | 02/17/2009 |
| 7473342 | Capillary array and capillary electrophoresis apparatus In a case where the temperature of capillaries cannot be controlled rapidly in accordance with the change of the amount of heat generated from the capillaries, the phoretic speed of the sample is not controlled constant to lower the analyzing performance for the sam... | 01/06/2009 |
| 7449096 | Apparatus for the operation of a microfluidic device In a system for operation or handling of a laboratory microchip (41) for chemical processing or analysis, the microchip (41) is mounted in a first physical unit (42). The microchip (41) is arranged on a mounting plate, such that it is rea... | 11/11/2008 |
| 7439075 | Method and device for withdrawing suspended microparticles from a fluidic microsystem A method of discharging a fluid flow with suspended microparticles from a fluidic microsystem (10) is described, whereby the fluid flow converges with at least one output flow to form a discharge flow at the end of a discharge channel (14) of the micro... | 10/21/2008 |
| 7438793 | Capillary array having load header A multi-capillary array which can be used for a multi-capillary electrophoresis apparatus to effectively disperse the heat generated within a load header. In a load header of the capillary array used for the multi-capillary electrophoresis, an insulated holder, a co... | 10/21/2008 |
| 7425254 | Fractionation of macro-molecules using asymmetric pulsed field electrophoresis A method and apparatus for fractionation of charged macro-molecules such as DNA is provided. DNA solution is loaded into a matrix including an array of obstacles. An alternating electric field having two different fields at different orientations is applied. The alt... | 09/16/2008 |
| 7422669 | Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream A microfluidic device and method for forming and dispensing minute volume segments of a material are described. In accordance with the present invention, a microfluidic device and method are provided for spatially confining the material in a focusing element. The de... | 09/09/2008 |
| 7419577 | Removal method for coating of polymer coated glass capillary tubing and polymer coated glass capillary tubing The present invention provides a method for producing a high-quality capillary tube used in an electrophoresis apparatus in a safe and inexpensive manner. A polymer coating on a capillary tube is converted into gas and removed through an oxidative reaction with oxyg... | 09/02/2008 |
| 7419576 | Analyzing apparatus One of the principal objects of the present invention is to realize, in a small scale and at a low cost, an analyzing apparatus that analyzes and manipulates a minute sample such as DNA. The analyzing apparatus 1 incorporates an optical system for measuring a... | 09/02/2008 |
| 7411184 | Microfluidic device comprising an electrospray nose A microfluidic device including a microfluidic chip assembled to an electrospray structure. The microfluidic chip includes at least one microfluidic channel leading through an outlet aperture to a surface area of the microfluidic chip. The electrospray structure inc... | 08/12/2008 |
| 7402229 | Fabrication and use of semipermeable membranes and gels for the control of electrolysis in a microfluidic device A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrode po... | 07/22/2008 |
| 7399398 | Variable potential electrokinetic devices Variable potential electrokinetic devices and electrokinetic multipliers used for pumping and flow control are disclosed that offer improvements in safety and design flexibility. The devices of the present invention take advantage of combinations of pumping conduits... | 07/15/2008 |
| 7396444 | Device to operate a laboratory microchip In a device to operate and handle a laboratory microchip to chemically process or analyze substances, the microchip is on a chip holder (41) that is part of a first assembly (42). The first assembly (42) also has an optical device (43) fo... | 07/08/2008 |
| 7390390 | Capillary array electrophoretic device and auto sampler used for the device A capillary array electrophoretic device capable of securing a sample plate array and a buffer container three dimensionally on a tray of an autosampler. A tray (700) is provided with a guide groove (701) and a stopper (702) corresponding to gui... | 06/24/2008 |
| 7384525 | Electrophoretic analysis system having in-situ calibration An electrophoretic system having a plurality of separation lanes is provided with an automatic calibration feature in which each lane is separately calibrated. For each lane, the calibration coefficients map a spectrum of received channel intensities onto values ref... | 06/10/2008 |
