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| Number | Title | Issue Date |
| 8021531 | Method for modifying the concentration of reactants in a microfluidic device A method of carrying out a chemical reaction on a microfluidic device in which a first reactant at a first concentration is delivered into a reaction channel; within the reaction channel the concentration of the first reactant is changed from the first concentration... | 09/20/2011 |
| 7951278 | Method of detecting directly undetectable analytes using directly detectable spacer molecules The present invention provides a method of indirectly detecting at least one directly undetectable analyte of interest. According to the method, a leading electrolyte and a trailing electrolyte are provided. In addition, a mixture of the at least one directly undete... | 05/31/2011 |
| 7397597 | Electrophoretic display panel An electrophoretic display panel for displaying a picture has a pixel having an electrophorectic medium having first and second charged particles, the first charged particles having a first optical property, the second charged particles having a second optical prope... | 07/08/2008 |
| 7327514 | Microscope system comprising actuator element for moving the objective lens for focussing A microscope system having a plurality of exchangeable objective lenses (10); an objective lens changeover element (18) for supporting each of the objective lenses which is operable for placing a selected one of said objective lenses into an optical ax... | 02/05/2008 |
| 7295311 | Methods and apparatus for electrophoretic mobility determination using phase light scattering analysis An apparatus and method are disclosed for determining electrophoretic mobility using scattering light phase analysis comprising emitting a laser light along a path and transmitting a first portion of the laser light and reflecting a second portion of the laser light... | 11/13/2007 |
| 7223325 | Method for orthogonal analyte stacking/injection systems in electrophoresis In the present capillary electrokinetic chromatograpy method, analytes are injected by electroosmotic flow directly from a sample matrix into a separation buffer containing an electrokinetic vector with an opposite mobility. Analytes can now be injected at the veloc... | 05/29/2007 |
| 7217350 | Mobility and effects arising from surface charge A method of, and apparatus for, automatically determining an electric charge—related characteristic or derived parameter of particles in a dispersion or of a cell wall, comprises having a particle—containing dispersion provided in a cell. The dispersion is illum... | 05/15/2007 |
| 7217901 | System for transporting and selectively sorting particles and method of using the same A system for transporting and selectively sorting particles includes a first wall and a traveling wave grid extending along the first wall. The system includes a second wall having a passage extending therethrough and a gate operatively associated with the passage. ... | 05/15/2007 |
| 7211183 | Analysis and fractionation of particles near surfaces A method and apparatus for fractionation of a mixture of particles and for particle analysis are provided, in which LEAPS (“Light-controlled Electrokinetic Assembly of Particles near Surfaces”) is used to fractionate and analyze a plurality of particles suspende... | 05/01/2007 |
| 7150812 | Method for continuous particle separation using obstacle arrays asymmetrically aligned to fields The present invention relates to methods and devices for separating particles according to size. More specifically, the present invention relates to a microfluidic method and device for the separation of particles according to size using an array comprising a networ... | 12/19/2006 |
| 7145320 | Particle counting method and particle counter A particle counter counts particles in aerosol having a particle size of from 2 nm to 50 nm in an operating pressure range from an atmospheric pressure through a reduced pressure to a low vacuum and calculate a particle size distribution. The particle counter charge... | 12/05/2006 |
| 7140239 | System and technique for ultrasonic characterization of settling suspensions A system for determining properties of settling suspensions includes a settling container, a mixer, and devices for ultrasonic interrogation transverse to the settling direction. A computer system controls operation of the mixer and the interrogation devices and rec... | 11/28/2006 |
| 7135144 | Method for the manipulation of a fluid sample The invention provides a device and method for the manipulation of materials (e.g., particles, cells, macromolecules, such as proteins, nucleic acids or other moieties) in a fluid sample. The device comprises a substrate having a plurality of microstructures and an ... | 11/14/2006 |
| 7116678 | High speed physical layer for CSMA/CD systems An electronic communications network technology, referred to as 100BASE-TD, offers full duplex operation and robust performance on marginal CAT5 wiring. It highly leverages 100BASE-TX functional blocks and is very complementary to 100BASE-TX, for example with regard... | 10/03/2006 |
| 7115423 | Fluidic structures within an array package A package for an addressable array of multiple features carried on a first side of a substrate, and a method of using such package. The package includes a housing which receives the substrate such that the housing and received substrate define a chamber into which t... | 10/03/2006 |
| 7111476 | Electrophoretic deposition process for making quartz glass products Cup-shaped porous silica preforms suitable for manufacture of large 24-inch crucibles used in Czochralski crystal-growing furnaces are produced by a unique electrophoretic casting process using a high-purity aqueous silica slip or slurry having a predetermined parti... | 09/26/2006 |
| 7072038 | Particle ID with narrow angle detectors A method for the identification of unknown particles contained in a fluid. The method utilizes a source of radiation and at least one radiation detector to measure the radiation scattered by an unknown particle in the fluid. The measurement for the unknown particle ... | 07/04/2006 |
| 7041510 | System and method for programmable illumination pattern generation A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on t... | 05/09/2006 |
| 6991941 | Light-controlled electrokinetic assembly of particles near surfaces A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on t... | 01/31/2006 |
| 6905583 | Closed-loop control of electrokinetic processes in microfluidic devices based on optical readings A method for performing an electrophoretic separation on a microfluidic device includes applying an electric field to electrokinetically move a sample along a channel towards a location. The sample may be concentrated by application of the electric field. The method... | 06/14/2005 |
| 6881315 | Fractionating apparatus having colonies of pillars arranged in migration passage at interval and process for fabricating pillars A fractionating apparatus is used for fractionating sample into micro-structures different in size, and includes a fractionating unit formed with a fractionating passage; the fractionating passage is defined in a groove formed in a substrate of the fractionating uni... | 04/19/2005 |
| 6706163 | On-chip analysis of particles and fractionation of particle mixtures using light-controlled electrokinetic assembly of particles near surfaces A method and apparatus for fractionation of a mixture of particles and for particle analysis are provided, in which LEAPS (“Light-controlled Electrokinetic Assembly of Particles near Surfaces”) is used to fractionate and analyze a plurality of particles suspende... | 03/16/2004 |
| 6685813 | Tandem isotachophoresis/zone electrophoresis method and system A method of separating components having a given negative or positive charge and contained in a sample is disclosed. The method involves, in one embodiment, loading a microchannel with a sample, placed between a trailing-edge electrolyte having a selected... | 02/03/2004 |
| 5614072 | Increased efficiency of electrophoretic separations by mobility matching The invention concerns electrophoresis and methods and electrolyte compositions for decoupling or isolating the dual functions of the electrolyte composition in order to increase separation selectivity or reduce electromigration dispersion, or both. An el... | 03/25/1997 |
| 5582701 | Ionic liquid-channel charge-coupled device An ionic liquid-channel charge-coupled device that separates ions in a liquid sample according to ion mobility characteristics includes a channel having an inner wall that has a matrix liquid disposed within. An insulating material surrounds the channel, ... | 12/10/1996 |
| 5562812 | Free flow electrophoresis device for biomolecule purification and separation in zero and one G An electrophoresis device is disclosed which may be partially disassembled and sterilized in an autoclave. The device includes a base and support framework extending from the base. A separation column including a separation chamber having a pair of plates... | 10/08/1996 |
| 5503723 | Isolation of ultra small particles The present invention is a method and apparatus for further reducing the size of nanoparticles. Nanoparticles are defined as having an effective average particle size of less than about 400 nm. The present invention separates the nanoparticles further usi... | 04/02/1996 |
| 5476992 | In-situ remediation of contaminated heterogeneous soils A process for the in-situ remediation of a contaminated heterogeneous soil region comprising: (a) introducing material for treating contaminants in a contaminated heterogeneous soil region into at least one liquid permeable region within the contaminated ... | 12/19/1995 |
| 5453163 | Electrokinetic packing of capillary columns Capillary columns are packed using electroosmotic flow (EOF) induced by an electrical double layer on the internal wall of a fused silica capillary and the electrophoretic mobility of positively-charged or negatively-charged particles of packing material.... | 09/26/1995 |
| 5439571 | Apparatus and method for enhanced resolution continuous flow zone electrophoresis An apparatus and method of continuous flow zone electrophoresis for separation of particulates or biological samples, including cells and sub-cellular components, in a separation chamber configured to enhance separation of the sample components. The peak-... | 08/08/1995 |
| 5427663 | Microlithographic array for macromolecule and cell fractionation A sorting apparatus and method for fractionating and simultaneously viewing individual microstructures, such as free cells, viruses, macromolecules, or minute particles in a fluid medium. The sorting apparatus is composed of a substrate having a receptacl... | 06/27/1995 |
| 5380410 | Process for fabricating an optical device for generating a second harmonic optical beam A method for fabricating an SHG device by forming an inversion region having a first direction of polarization selectively in a ferroelectric substrate that has a second, opposite direction of polarization. A proton exchange process exchanges cations in t... | 01/10/1995 |
| 5348633 | Method for quantitating trace amounts of an analyte in a sample by affinity capillary electrophoresis A method for quantitative detection of trace amounts of an analyte in a sample is disclosed. The method in the preferred embodiment includes providing an Fab' fragment of an immunoglobulin labelled at a reactive sulfhydryl group with a fluorescent dye; co... | 09/20/1994 |
| 5306412 | Method and apparatus for improving electrospray ionization of solute species The subject invention teaches the use of mechanical vibration to enhance the electrostatic dispersion of sample solutions into the small, highly charged droplets that can produce ions of solute species for mass spectrometric analysis. Such vibration turns... | 04/26/1994 |
| 5240618 | Electrical field-flow fractionation using redox couple added to carrier fluid Improved apparatus and procedures for electrical field-flow fractionation is disclosed. A test sample is injected into the liquid carrier stream flowing through the flow channel of the apparatus. The apparatus comprises a thin flow channel having a top, a... | 08/31/1993 |
| 5209834 | Ordered transport and identification of particles A method and apparatus are provided for application of electrical field gradients to induce particle velocities to enable particle sequence and identification information to be obtained. Particle sequence is maintained by providing electroosmotic flow for... | 05/11/1993 |
| 5200050 | Electrophoretic processor and methods An electrophoretic processor for separating proteins and other chemicals exhibiting varying electrophoretic mobilities. The preferred processor includes a rotor which turns within a stator to define a processing chamber therebetween. The rotor and stator ... | 04/06/1993 |
| 5183542 | Apparatus and method for separating zirconium isotopes using balanced ion electromigration Both a method and apparatus for separating zirconium isotopes by balanced ion migration in a counterflowing electrolyte are disclosed herein. In the method of the invention, zirconium chloride is dissolved in a solution of HCl, and a voltage of between 2 ... | 02/02/1993 |
| 5131994 | Electrophoresis method and apparatus The present invention relates to a method and apparatus for effecting an electrophoretic separation of charged particles. A fractionation chamber comprising a semipermeable membrane is used wherein a transmembrane force holds the particles to be separated... | 07/21/1992 |
| 5108568 | Controlled method of reducing electrophoretic mobility of macromolecules, particles or cells A method of reducing electrophoretic mobility of macromolecules, particles, cells and other substances is provided which comprises interacting in a conventional electrophoretic separating procedure the substances with a polymer-linked affinity compound co... | 04/28/1992 |
