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Class 204/469 - Gel composition (other than simple agarose or polyacrylamide)


Subclass of Class 204 - Chemistry: electrical and wave energy
Definition: Subject matter drawn to (a) gel compositions (other than
No. of patents: 126
Last issue date: 05/15/2012


1        
NumberTitleIssue Date
8177950Thermoresponsive microparticle composite hydrogels for electrophoresis
Disclosed are thermoresponsive microparticle composite hydrogels comprising poly(N-isopropyl acrylamide) and polyacrylamide, and methods regarding their manufacture and their use. The present invention provides in one aspect a thermoresponsive microparticle hydrogel...
05/15/2012
8034224Electrophoresis gel and method of making same
An electrophoresis gel has a colored or pigmented loading area at one edge having a plurality of sample wells for receiving samples, the loading area extending beyond the ends of the wells so that the wells can be visually differentiated from the surrounding colored...
10/11/2011
7967966System for pH-neutral stable electrophoresis gel
A gel and buffer system for gel electrophoresis wherein separation occurs at neutral pH. ...
06/28/2011
7799195Neutral polysaccharide wall coating for electrophoretic separations in capillaries and microchannels
The present invention describes a method of preparation of a permanent neutral wall coating made of thermally immobilized polysaccharides. The coating suppresses electroosmotic flow and adsorption on the wall under acidic, neutral, and basic conditions in capillary ...
09/21/2010
7799194Electrophoretic gels and their manufacture
The invention relates to a method of preparing a gel for use in electrophoresis, which method comprises: (a) providing a mixture comprising a solvent, agarose or a derivative thereof, one or more vinyl monomers, and a polymerisation initiator, the initiator f...
09/21/2010
7794576Protein resolution enhancement by using matrix containing DMSO
An electrophoresis gel matrix is provided for conducting proteomics, in particular the steps of separating and/or identifying proteins. The matrix comprises at least one chemical reagent being at least one of a denaturing, buffering, disaggregating, reducing, staini...
09/14/2010
7731829Electrophoresis gel and method of making same
An electrophoresis gel has a colored or pigmented loading area at one edge having a plurality of sample wells for receiving samples, the loading area extending beyond the ends of the wells so that the wells can be visually differentiated from the surrounding colored...
06/08/2010
7682497Thermo-gelling matrices for microchannel DNA sequencing
Polymeric compounds and related methods and apparatus, as can be used in a wide range of RNA and DNA separations. ...
03/23/2010
7399396Sparsely cross-linked nanogels: a novel polymer structure for microchannel DNA sequencing
The present invention is generally directed to novel polymeric mateirals for use in the electrophoretic separation of nucleic acids. In particular, the novel polymer materials are sparsely crosslinked nanogels, dissolved in an aqueous buffer to form solutions with m...
07/15/2008
7326324Purification and use of gellan in electrophoresis gels
Gellan can be purified from nucleic acid contamination by combining the contaminated gellan with DNase under conditions that allow the DNase to degrade the nucleic acid contaminant. The purified gellan is useful in gel electrophoresis. A buffer which allows cystamin...
02/05/2008
7326326System and methods for electrophoretic separation of proteins on protein binding membranes
Proteins can be rapidly separated to a high degree of resolution by electrophoresis on polymeric membranes that have high protein binding capacity. The electrophoretic separation is carried out in a low conductivity, water-miscible organic solvent buffer. The low co...
02/05/2008
7323092Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis
While the present invention has been described in conjunction with a preferred embodiment, one of ordinary skill, after reading the foregoing specification, will be able to effect various changes, substitutions of equivalents, and other alterations to the compositio...
01/29/2008
7323140Moving microdroplets in a microfluidic device
The present invention relates to a system and method for moving samples, such as fluid, within a microfluidic system using a plurality of gas actuators for applying pressure at different locations within the microfluidic. The system includes a substrate which forms ...
01/29/2008
7320747Gel for electrophoresis
The present invention is directed to a solidified hybrid gel for use in an electrophoresis process, having a solidified first gel portion juxtaposed with a solidified second gel portion. The first gel portion is capable of accommodating therein one or more samples f...
01/22/2008
7314708Method and apparatus for electronic synthesis of molecular structures
A self-addressable, self-assembling microelectronic device is designed and fabricated to actively carry out and control multi-step and multiplex molecular biological reactions in microscopic formats. These reactions include nucleic acid hybridization, antibody/antig...
01/01/2008
7314584Polymer gel composition and optical device using the same
The present invention provides a polymer gel composition including: at least two polymer compounds which interact with each other to form a polymer complex; and a liquid. One of the polymer compounds forms a three-dimensional crosslinked structure, at least one othe...
01/01/2008
7282127Microcapillary devices using high dielectric constant materials and related methods
A microcapillary device includes a microcapillary tube. An anode is positioned at a first end of the microcapillary tube. A cathode is positioned at a second end of said microcapillary tube. A plurality of electric field reducing components are spaced apart along a ...
10/16/2007
7270786Methods and systems for processing microfluidic samples of particle containing fluids
The present invention relates to a microfluidic system for processing a cell-containing liquid. The system includes a microfabricated substrate having an enrichment channel to prepare an enriched cell sample from the cell-containing liquid. A flow through member is ...
09/18/2007
7259217Controlled-architecture polymers and use thereof as separation media
Controlled architecture polymers made preferably with acrylamide type monomers are prepared in living-type or semi-living-type free radical polymerizations, with the architecture preferably being other than linear, such as star, branched, grafted or hyper-branched. ...
08/21/2007
7255781Production of aligned microfibers and nanofibers and derived functional monoliths
The present invention comprises a method for producing microfibers and nanofibers and further fabricating derived solid monolithic materials having aligned uniform micro- or nanofibrils. A method for producing fibers ranging in diameter from micrometer-sized to nano...
08/14/2007
7233481Electric double layer capacitor and electrolyte solution therefor
An electric double layer capacitor has a pair of activated carbon electrodes and an organic solution in which an electrolyte is dissolved in an organic solvent. An electrolyte solution is also provided. In the electric double layer capacitor, at least one of cycloal...
06/19/2007
7229539Destructible surfactants and uses thereof
Destructible surfactants and methods of using same are provided. The invention includes anionic surfactants having a dioxolane or dioxane functional group which enables the surfactant to be broken down under acidic conditions. The invention also includes methods of ...
06/12/2007
7217348Methods of identifying kinetically stable proteins
The present invention provides a fast and efficient means for identifying kinetically stable proteins. As used herein the term “kinetically stable protein” means a protein that is trapped in a specific conformation due to an unusually high unfolding barrier that...
05/15/2007
7198703Chamber-forming electrophoresis cassette cover
A multielevational cover for assembling a fluid retaining chamber on a face of an electrophoresis cassette is presented. The cover comprises a cassette-containing member, at least one chamber-defining member, and sealing means, typically sealing means that are capab...
04/03/2007
7192557Methods and systems for releasing intracellular material from cells within microfluidic samples of fluids
The present invention relates to a microfluidic system for processing a cell-containing liquid. The system includes a lysing zone to receive the cell-containing sample and a positioning element to position the cell-containing sample in a lysing position in the vicin...
03/20/2007
7179357Serial sample injection in capillary electrophoresis
The invention is a method of performing electrophoresis that increases sample throughput and increases the efficiency and speed of the analysis of polynucleotides by electrophoresis. The method is performed by loading and running multiple sequential samples on each ...
02/20/2007
7172896Integrated portable biological detection system
We have performed separation of bacterial and cancer cells from peripheral human blood in microfabricated electronic chips by dielectrophoresis. The isolated cells were examined by staining the nuclei with fluorescent dye followed by laser induced fluorescence imagi...
02/06/2007
7156969Microfluidic matrix localization apparatus and methods
Multiphasic microfluidic apparatus for performing product fluid manipulation and separation in a single continuous unit are provided. Related methods, kits, and compositions are also provided. ...
01/02/2007
7153955Pentopyranosyl nucleic acid arrays, and uses thereof
The invention relates to a pentopyranosylnucleoside of the formula (I) or of the formula (II) their preparation and use for the production of a therapeutic, diagnostic and/or electronic component. ...
12/26/2006
7147762Method of electrophoresis
The present invention relates a method of electrophoretic separation of protein and/or peptide components of a sample in a convection stabilized medium. More specifically, the method comprises the steps to contact the sample with the separation medium; to apply a vo...
12/12/2006
7118900Directed assembly of functional heterostructures
The present invention relates to a systematic process for the creation of functionally organized, spatially patterned assemblies of polymer-microparticle composites including the AC electric field-mediated assembly of patterned, self-supporting organic (polymeric) f...
10/10/2006
7101661Apparatus for active programmable matrix devices
A system for performing molecular biological diagnosis, analysis and multistep and multiplex reactions utilizes a selfaddressable, selfassembling microelectronic system for actively carrying out controlled reactions in microscopic formats. Preferably, a fluidic syst...
09/05/2006
7083711Capillary electrophoresis gel especially for separation made for single stranded nucleic acid separations
A separation matrix for capillary electrophoresis of single-stranded nucleic acids is disclosed. The matrix comprises an aqueous buffer containing a denaturant and (hydroxypropyl)methyl cellulose. ...
08/01/2006
7056426Pre-cast electrophoresis slab gels with extended storage life
In pre-cast slab gel cassettes, the formation of pathways in which proteins can migrate between the gel and the walls of the cassette to form shadow bands is avoided by including a nonionic amphiphilic polymer in the monomer solution from which the gel is formed and...
06/06/2006
7052590Method and kit for the manufacture of separation gels
A method for the manufacture of a separation gel, which comprises the steps: (i) providing a polymerization mixture containing a first monomer (I) having a polymerizable unsaturated structure and a second monomer (II) comprising two or more polymerizable unsaturated...
05/30/2006
7005050Electrophoresis in microfabricated devices using photopolymerized polyacrylamide gels and electrode-defined sample injection
The present invention relates to a novel, small-scale, electrophoretic separation system based on photodefined polymers and electrode-defined sample injection. Diffusion and displacement coefficients may be modified by varying the gel concentration, the intensity of...
02/28/2006
6942775Vertical electrophoresis system
A plugging medium is used to block the bottom opening of cassettes for vertical electrophoresis in order to facilitate filling the cassettes with separation media. Cassettes can be filled within a vertical electrophoresis system in which electrophoresis is conducted...
09/13/2005
6939453Electrophoresis process using ionic liquids
Highly hydrophobic compounds and hydrophobic proteins are solubilized in a non-aqueous solvent containing an electrolyte for electrophoretic separation. The non-aqueous solvent is an ionic liquid or a mixture of an organic solvent containing an ionic liquid in an am...
09/06/2005
6926815Copolymers for capillary gel electrophoresis
This invention relates to an electrophoresis separation medium having a gel matrix of at least one random, linear copolymer comprising a primary comonomer and at least one secondary comonomer, wherein the comonomers are randomly distributed along the copolymer chain...
08/09/2005
6878254Size separation of analytes using monomeric surfactants
A sieving medium for use in the separation of analytes in a sample containing at least one such analyte comprises a monomeric non-ionic surfactant of the of the general formula, B-A, wherein A is a hydrophilic moiety and B is a hydrophobic moiety, present in a solve...
04/12/2005
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