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...When G.G. Hubbard learned of his future son-in-law's invention, he called it "only a toy." His daughter was engaged to a young man named Alexander Graham Bell.
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| Number | Title | Issue Date |
| 8007646 | Fluorescent detection of proteins in polyacrylamide gels The mechanism of the UV light-induced reaction between the indole moiety of tryptophan and chloroform, and the structure of the modified tryptophan and polypeptides including such modified tryptophan residues. The excited indole moiety, which is formed upon UV light... | 08/30/2011 |
| 7901559 | Polyacrylamide gel for electrophoresis, polyacrylamide gel electrophoresis method using the same, method of producing the same, and acrylamide compound It is intended to provide a method for easily detecting a phosphorylated peptide (protein) in a test sample by using SDS-polyacrylamide gel electrophoresis (SDS-PAGE) which has been conventionally employed in analyzing a protein; a polyacrylamide gel for electrophor... | 03/08/2011 |
| 7901558 | Integrated 2D gel electrophoresis method and system Described is a process for the separation of a sample mixture for analytical reason based on two-dimensional gel electrophoresis. The method is involving a first separation in a first gel strip on the basis of isoelectric points and a second separation in a second g... | 03/08/2011 |
| 7828949 | Biomolecule detection device, mobile phone for biomolecule detection, and biomolecule detection method Provided are a biomolecule detection device, a mobile phone for biomolecule detection, and a biomolecule detection method. The biomolecule detection device includes an electrophoresis unit comprising an electrophoretic gel filtering erythrocytes and leukocytes in bl... | 11/09/2010 |
| 7824532 | Apparatus and method for electrophoresis Apparatus for conducting electrophoresis therein includes a chamber with a gel matrix. The chamber has a first sealed region and a second sealed region, and an anode within the first sealed region of the chamber and in contact with the gel matrix, and a cathode with... | 11/02/2010 |
| 7811435 | Method for scanning gels and gel folder for use in the method The present invention relates to a method of scanning an electrophoretic gel after electrophoresis of fluorescence labelled samples, comprising inserting the gel into a separate low fluorescent scanning unit, in the shape of a gel folder or a frame, and scanning the... | 10/12/2010 |
| 7749366 | Isolation and cloning of DNA from uncultivated organisms The present invention relates to a device for the isolation and/or purification of nucleic acid molecules suitable to bind and/or inactivate inhibitors of the activity of reagents or enzymes used for DNA manipulation and to separate a plurality of nucleic acid molec... | 07/06/2010 |
| 7435388 | Applicator of a fluid sample on a substrate Applicator of a fluid sample on a substrate, wherein at least an applying blade substantially of rectangular shape in its turn defining a body of the blade, a tip of the blade and two facing side edges of the blade, wherein each blade has a drain of the body of the ... | 10/14/2008 |
| 7422670 | System for pH-neutral stable electrophoresis gel A gel and buffer system for gel electrophoresis wherein separation occurs at neutral pH. ... | 09/09/2008 |
| 7399394 | Electrophoresis device, electrophoresis method using an electrophoresis device and use of the electrophoresis device An electrophoresis device having a separation chamber that is provided with at least one sample inlet on the inlet side and outlets (9) for the electrophoretically treated sample species on the outlet side. The separation chamber is divided into two chamber p... | 07/15/2008 |
| 7399395 | Method and device for generating microconvections The invention relates to a method for generating a convective liquid motion in a fluidic microsystem. According to this method, a liquid in a microsystem is simultaneously exposed to an electrical field and a thermal gradient. The electrical field is generated by me... | 07/15/2008 |
| 7393443 | Methods of identifying kinetically stable proteins The present invention provides a fast and efficient means for identifying kinetically stable proteins. As used herein the term “kinetically stable protein” means a protein that is trapped in a specific conformation due to an unusually high unfolding barrier that... | 07/01/2008 |
| 7374649 | Dispersion of carbon nanotubes by nucleic acids Carbon nanotubes dispersed by a stabilized solution of nucleic acid molecules formed separated nanotube-nucleic acid complexes and were separated according to standard chromatographic methods, including gel electrophoresis, two phase solvent systems and ion exchange... | 05/20/2008 |
| 7365847 | Method and apparatus for automated excision of samples from two-dimensional electrophoresis gels A system for automated excision of one or more samples from a sample media, including by using a device for electronically capturing one or more traits of samples in the media, using a microprocessor linked to the device to analyze the captured traits by comparison ... | 04/29/2008 |
| 7361260 | Methods, articles and kits for labeling polymer gels The invention provides methods, apparatus and kits for integrally labeling polymeric gels, such as polyacrylamide and agarose gels, with indicia that can serve, inter alia, unambiguously to identify the individual gel, using polymeric film labeled with detectable in... | 04/22/2008 |
| 7361308 | Spot picker device and method for picking gel plugs The present invention relates to devices and methods for removing gels plugs (47) from a gel(3) bonded to a surface (5) wherein means are provided for rotating the gel plug before lifting it from said surface. The rotation of the gel plug is int... | 04/22/2008 |
| 7347922 | Multi-dimensional proteomic analysis method A multi-dimensional proteomic analysis method utilizing cationic electrophoresis is described. The method includes separating proteins in one direction using cationic electrophoresis and separating the proteins in a second orthogonal direction using other electropho... | 03/25/2008 |
| 7332268 | Layered support sheet for high-yield spot cutting from gels or membranes The excision of sample spots from a gel or membrane by pressing a cutting tool terminating in a hollow cylinder against the gel or membrane supported on a rigid surface is made more reliable by interposing a relatively pliable, intermediate layer on the side of the ... | 02/19/2008 |
| 7323092 | Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis While the present invention has been described in conjunction with a preferred embodiment, one of ordinary skill, after reading the foregoing specification, will be able to effect various changes, substitutions of equivalents, and other alterations to the compositio... | 01/29/2008 |
| 7320747 | Gel for electrophoresis The present invention is directed to a solidified hybrid gel for use in an electrophoresis process, having a solidified first gel portion juxtaposed with a solidified second gel portion. The first gel portion is capable of accommodating therein one or more samples f... | 01/22/2008 |
| 7310625 | Knowledge network generation A knowledge-based system has one or more repositories with information and knowledge for topics, problems, and solutions to problems. One method to find a solution for a problem by generating a knowledge network in a master knowledge repository includes identifying ... | 12/18/2007 |
| 7309409 | Multi-channel bio-separation cartridge A bio-separation system using an efficient, compact, portable, interchangeable, reusable, recyclable, multi-channel cartridge, has integrated pre-aligned optics and an integrated reagent reservoir. The cartridge supports, for example, multiple capillaries for CE sep... | 12/18/2007 |
| 7284409 | Thermal modulation for gas chromatography A thermal modulator device for gas chromatography and associated methods. The thermal modulator device includes a cooling member, an electrically conductive capillary in direct thermal contact with the cooling member, and a power supply electrically coupled to the c... | 10/23/2007 |
| 7282126 | System and method for determining known DNA variants with temperature gradient electrophoresis The present invention relates to a method of determining the genotype of a sample polynucleotide having at least a first variant site. At least a portion of the sample polynucleotide is amplified to obtain first amplicons, the first amplicons including the first var... | 10/16/2007 |
| 7282128 | Buffers for electrophoresis and use thereof Various embodiments provide, for example, buffer compositions and/or sieving formulations useful in connection with electrophoresis instruments, such as capillary electrophoresis (CE) devices. In various embodiments, a buffer composition can include Bis-Tris, TAPS a... | 10/16/2007 |
| 7280266 | Electrophoretic display medium and device An electrophoretic display medium includes at least one set of colored particles in a dielectric fluid, wherein the display medium has an electrical conductivity of about 10−11 to about 10−15 S/m. The display medium is included in an electr... | 10/09/2007 |
| 7276143 | Electrophoresis module having electrophoresis bath with upright carriers The electrophoresis module has an upright cassette of which at least one of the front and rear sides has a recess opened upwardly, the recess has on the peripheral edge thereof a buffering member; the cassette has on the two ends thereof a clamping assembly each, ea... | 10/02/2007 |
| 7264703 | Gel trap for electrophoresis An apparatus for electrophoresis having a first gel matrix, adapted for performing an electrophoretic process therein, in communication with a second gel matrix, both being accommodated within a suitable housing. The housing has a first opening adapted to permit ion... | 09/04/2007 |
| 7261800 | Automatic in situ electrophoresis method and apparatus A method of in situ electrophoresis of biological samples has the steps of preparing a sample plate and a gel plate, applying reagent onto the gel plate, moving an applicator to the sample plate so as to receive a sample onto the applicator, moving the applicator to... | 08/28/2007 |
| 7259217 | Controlled-architecture polymers and use thereof as separation media Controlled architecture polymers made preferably with acrylamide type monomers are prepared in living-type or semi-living-type free radical polymerizations, with the architecture preferably being other than linear, such as star, branched, grafted or hyper-branched. ... | 08/21/2007 |
| 7255781 | Production of aligned microfibers and nanofibers and derived functional monoliths The present invention comprises a method for producing microfibers and nanofibers and further fabricating derived solid monolithic materials having aligned uniform micro- or nanofibrils. A method for producing fibers ranging in diameter from micrometer-sized to nano... | 08/14/2007 |
| 7250100 | Two dimensional electrophoresis cassette A device for two-dimensional electrophoresis includes a cassette comprising two opposing plates. The two opposing plates form a first elongated portion for receiving a first elongated electrophoretic separation medium and a second portion extending away from the fir... | 07/31/2007 |
| 7235123 | Particle transport and near field analytical detection Particle collection, transport, and detection systems are disclosed. The systems are uniquely adapted for collecting or concentrating particles from a flowing medium and then transporting the collected particles to a desired location or for subsequent analysis. Elec... | 06/26/2007 |
| 7229539 | Destructible surfactants and uses thereof Destructible surfactants and methods of using same are provided. The invention includes anionic surfactants having a dioxolane or dioxane functional group which enables the surfactant to be broken down under acidic conditions. The invention also includes methods of ... | 06/12/2007 |
| 7217350 | Mobility and effects arising from surface charge A method of, and apparatus for, automatically determining an electric charge—related characteristic or derived parameter of particles in a dispersion or of a cell wall, comprises having a particle—containing dispersion provided in a cell. The dispersion is illum... | 05/15/2007 |
| 7217348 | Methods of identifying kinetically stable proteins The present invention provides a fast and efficient means for identifying kinetically stable proteins. As used herein the term “kinetically stable protein” means a protein that is trapped in a specific conformation due to an unusually high unfolding barrier that... | 05/15/2007 |
| 7214299 | Method for separation, identification and evaluation of microbes and cells The method entails using capillary electrophoresis or capillary isoelectric focusing to separate intact microbes. The capillary system can be a conventional capillary tube or a microfluidic device. The method is employed to maintain the microbes intact to ide... | 05/08/2007 |
| 7211181 | Photoelectrochemical molecular comb A method, system, and apparatus are provided for separating molecules, such as biomolecules. The method, system, and apparatus utilize an electrochemical cell having at least to electrodes, one electrode comprising a photo-sensitive material capable of generating a ... | 05/01/2007 |
| 7204922 | Method and device for the electrophoretic separation of particles, especially of macromolecules, by electrophoresis The present invention provides a method for the electrophoretic separation of particles, especially of macromolecules, comprising the steps of applying the particles to be separated on a substrate supported membrane, such that the particles are mobile across the sur... | 04/17/2007 |
| 7198703 | Chamber-forming electrophoresis cassette cover A multielevational cover for assembling a fluid retaining chamber on a face of an electrophoresis cassette is presented. The cover comprises a cassette-containing member, at least one chamber-defining member, and sealing means, typically sealing means that are capab... | 04/03/2007 |
