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A mouse device for use as an input device of a computer is provided that includes a housing in which recording paper is loadable, and a printer unit provided within the housing for printing on the recording paper print information received from the computer.

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Class 204/454 - With adjustment or alteration of electro-osmotic bulk flow


Subclass of Class 204 - Chemistry: electrical and wave energy
Definition: Process which provides for adjustment or alteration of continuous
No. of patents: 174
Last issue date: 01/17/2012


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NumberTitleIssue Date
8097140Liquid sample analysis methods
A method for collecting an analyte species from a sample is provided, the method of collection potentially being supplemented to give a method of preparing a sample for analysis and/or a method of analysis. The method including providing part of a sample in a substr...
01/17/2012
7439075Method and device for withdrawing suspended microparticles from a fluidic microsystem
A method of discharging a fluid flow with suspended microparticles from a fluidic microsystem (10) is described, whereby the fluid flow converges with at least one output flow to form a discharge flow at the end of a discharge channel (14) of the micro...
10/21/2008
7431888Photoinitiated grafting of porous polymer monoliths and thermoplastic polymers for microfluidic devices
A microfluidic device preferably made of a thermoplastic polymer that includes a channel or a multiplicity of channels whose surfaces are modified by photografting. The device further includes a porous polymer monolith prepared via UV initiated polymerization within...
10/07/2008
7347617Mixing in microfluidic devices
Mixing of liquids in a microfluidic device is accomplished by dispensing the liquids into a first chamber to produce combined liquid. The liquids are thereafter discharged through at least one capillary from the first chamber into a second chamber for complete mixin...
03/25/2008
7334630Closed-loop microchannel cooling system
Apparatus and methods according to the present invention utilize micropumps that are capable of generating high pressure and flow without moving mechanical parts and the associated generation of unacceptable electrical and acoustic noise, as well as the associated r...
02/26/2008
7323140Moving microdroplets in a microfluidic device
The present invention relates to a system and method for moving samples, such as fluid, within a microfluidic system using a plurality of gas actuators for applying pressure at different locations within the microfluidic. The system includes a substrate which forms ...
01/29/2008
7318912Microfluidic systems and methods for combining discrete fluid volumes
Microfluidic devices capable of combining discrete fluid volumes generally include channels for supplying different fluids toward a sample chamber and means for establishing fluid communication between the fluids within the chamber. Discrete fluid plugs are defined ...
01/15/2008
7316543Electroosmotic micropump with planar features
An electroosmotic micropump having a plurality of thin, closely-spaced, approximately planar, transversel aligned partitions formed in or on a substrate, among which electroosmotic flow (EOF) is generated. Electrodes are located within enclosed inlet and outlet mani...
01/08/2008
7316769Length-dependent recoil separation of long molecules
Separation of long molecules by length is obtained by forcing such molecules to traverse a boundary between a low free-energy region and a high free-energy region. In one embodiment, the high free-energy region is a dense pillar region or other structure formed on a...
01/08/2008
7316320Sorting charged particles
Charged particles may undergo two different separations within a single device, without manual intervention to effect the transfer of the particles between separations. In some embodiments, the device may be a Micro-Electro-Mechanical System. ...
01/08/2008
7314708Method and apparatus for electronic synthesis of molecular structures
A self-addressable, self-assembling microelectronic device is designed and fabricated to actively carry out and control multi-step and multiplex molecular biological reactions in microscopic formats. These reactions include nucleic acid hybridization, antibody/antig...
01/01/2008
7285421Apparatus for capillary electrophoresis and associated method
An apparatus and method for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage defined by passage walls comprising fused silica. The poly...
10/23/2007
7282127Microcapillary devices using high dielectric constant materials and related methods
A microcapillary device includes a microcapillary tube. An anode is positioned at a first end of the microcapillary tube. A cathode is positioned at a second end of said microcapillary tube. A plurality of electric field reducing components are spaced apart along a ...
10/16/2007
7270786Methods and systems for processing microfluidic samples of particle containing fluids
The present invention relates to a microfluidic system for processing a cell-containing liquid. The system includes a microfabricated substrate having an enrichment channel to prepare an enriched cell sample from the cell-containing liquid. A flow through member is ...
09/18/2007
7258839Temperature controlled microfabricated two-pin liquid sample dispensing system
A cooled liquid sample dispensing system comprises a pair of pins for holding a droplet of liquid therebetween and a cooling element. Each pin includes a tip spaced predetermined distance from the other pin to define a sample acquisition region. The pins acquire and...
08/21/2007
7252928Methods for prevention of surface adsorption of biological materials to capillary walls in microchannels
Methods for reducing surface adsorption of biological materials to the walls of microfluidic conduits in microscale devices are provided. In an example of the methods, one or more colloidal-size particles, such as colloidal silica particles, are flowed in a fluid wi...
08/07/2007
7243670Microfluidic system
A microfluidic system, particularly a microfluidic chip, with at least one operational channel, in which a fluid and/or the constituents contained therein are moveable in the direction of the operational channel by a driving force, particularly by using pressure, ac...
07/17/2007
7231839Electroosmotic micropumps with applications to fluid dispensing and field sampling
Apparatus and methods according to the present invention preferably utilize electroosmotic pumps in fluid handling and field sampling applications. The electroosmotic pumps used in these applications are capable of generating high pressure and flow without moving me...
06/19/2007
7226562Liquid analysis cartridge
The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of particle capture regions. The storage channel is preferably an isotropic spa...
06/05/2007
7223325Method for orthogonal analyte stacking/injection systems in electrophoresis
In the present capillary electrokinetic chromatograpy method, analytes are injected by electroosmotic flow directly from a sample matrix into a separation buffer containing an electrokinetic vector with an opposite mobility. Analytes can now be injected at the veloc...
05/29/2007
7223327Method of preparing free polyelectrolyte membranes
A releaseable membrane structure for producing a free membrane containing a substrate, a release stratum on the substrate and a membrane stratum on the release stratum. The release stratum and the membrane stratum contain oppositely-charged polyelectrolytes that are...
05/29/2007
7216660Method and device for controlling liquid flow on the surface of a microfluidic chip
The invention is directed to a method and device for routing, mixing, or reacting droplets or liquid microstreams along the surface of a flat substrate. The flow of liquid microstreams or microdroplets along designated pathways is confined by chemical surface patter...
05/15/2007
7214299Method for separation, identification and evaluation of microbes and cells
The method entails using capillary electrophoresis or capillary isoelectric focusing to separate intact microbes. The capillary system can be a conventional capillary tube or a microfluidic device. The method is employed to maintain the microbes intact to ide...
05/08/2007
7201834Methods and compositions for modifying the surface of a polymeric substrate
Methods and compositions for modifying the surface of a polymeric substrate are provided. In the subject methods, at least a portion of the surface of the polymeric substrate is contacted with a biofouling resistant surfactant composition. At least a portion of the ...
04/10/2007
7192557Methods and systems for releasing intracellular material from cells within microfluidic samples of fluids
The present invention relates to a microfluidic system for processing a cell-containing liquid. The system includes a lysing zone to receive the cell-containing sample and a positioning element to position the cell-containing sample in a lysing position in the vicin...
03/20/2007
7189358Integrated micropump analysis chip and method of making the same
An integrated micropump or a plurality of integrated micropumps are communicated to a plurality of analysis chambers. A plurality of integrated analysis chambers include integrated analysis devices to test a fluid for an analyte. The micropumps continuously or perio...
03/13/2007
7185697Electroosmotic microchannel cooling system
Apparatus and methods according to the present invention preferably utilize electroosmotic pumps that are capable of generating high pressure and flow without moving mechanical parts and the associated generation of unacceptable electrical and acoustic noise, as wel...
03/06/2007
7179423Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
A fluid interface port in a microfluidic system and a method of forming the fluid interface port is provided. The fluid interface port comprises an opening formed in the side wall of a microchannel sized and dimensioned to form a virtual wall when the microchannel i...
02/20/2007
7172864Methods for electronically-controlled enzymatic reactions
A self-addressable, self-assembling microelectronic device is designed and fabricated to actively carry out and control multi-step and multiplex molecular biological reactions in microscopic formats. These reactions include nucleic acid hybridizations, antibody/anti...
02/06/2007
7172896Integrated portable biological detection system
We have performed separation of bacterial and cancer cells from peripheral human blood in microfabricated electronic chips by dielectrophoresis. The isolated cells were examined by staining the nuclei with fluorescent dye followed by laser induced fluorescence imagi...
02/06/2007
7163612Method, apparatus and article for microfluidic control via electrowetting, for chemical, biochemical and biological assays and the like
An active matrix microfluidic platform employs thin film transistor active (“TFT”) matrix liquid crystal display technology to manipulate small samples of fluid for chemical, biochemical, or biological assays without moving parts, for example, using a two-dimens...
01/16/2007
7156969Microfluidic matrix localization apparatus and methods
Multiphasic microfluidic apparatus for performing product fluid manipulation and separation in a single continuous unit are provided. Related methods, kits, and compositions are also provided. ...
01/02/2007
7153421Frit material and bonding method for microfluidic separation devices
A multi-layer microfluidic separation device comprises a polymeric membrane frit that may be securely bonded within the device and minimizes lateral wicking. Stationary phase material having an average particle size is retained by a frit having an average pore size ...
12/26/2006
7153955Pentopyranosyl nucleic acid arrays, and uses thereof
The invention relates to a pentopyranosylnucleoside of the formula (I) or of the formula (II) their preparation and use for the production of a therapeutic, diagnostic and/or electronic component. ...
12/26/2006
7155344Distributed database for analytical instruments
Techniques for controlling analytical instruments are provided. A sequence of steps can be utilized to specify wells of a microfluidic device, mobility to be applied to fluid in the wells, and the duration to apply the mobility. For example, fluids can be sequential...
12/26/2006
7134486Control of electrolysis gases in electroosmotic pump systems
Apparatus and methods according to the present invention preferably utilize electroosmotic pumps that are capable of generating high pressure and flow without moving mechanical parts and the associated generation of unacceptable electrical and acoustic noise, as wel...
11/14/2006
7131486Electroosmotic microchannel cooling system
Apparatus and methods according to the present invention preferably utilize electroosmotic pumps that are capable of generating high pressure and flow without moving mechanical parts and the associated generation of unacceptable electrical and acoustic noise, as wel...
11/07/2006
7130780Method and instrument for electronically recording and imaging fluid washover via measuring characteristics of the fluid at multiple locations simultaneously
An array of electrically isolated electrode pairs in combination with a specially configured processor, e.g., a personal computer, is employed to obtain a continuous real-time acquisition, processing, mapping and visualization of fluid washover. In a specific applic...
10/31/2006
7125711Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
A microliter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved by capillary forces into one or more metering wells which define the amount of the sample to be analyzed in subseque...
10/24/2006
7112361Methods of making decomposable thin films of polyelectrolytes and uses thereof
A decomposable thin film comprising a plurality of polyelectrolyte layers of alternating charge, wherein decomposition of the thin film is characterized by degradation of at least a portion of the polyelectrolyte layers. ...
09/26/2006
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