Did You Know...
...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 8163151 | Assays for detection of Von Willebrand factor (vWF) multimers and for degradation of vWF by agents such as Adamts13 and related methods Methods of analyzing the electrophoretic mobility distribution of von Willebrand factor (vWF) multimers include providing a sample medium comprising a plurality vWF multimers. The vWF multimers are electrophoretically separated by electrohoretic mobility in the samp... | 04/24/2012 |
| 8118986 | Determination of the hydrodynamic radii of the constituents of an admixture by means of analysis of a taylor dispersion carried out following a separation by means of capillary electrophoresis A method for determining the hydrodynamic radius for the constituents of an admixture, includes: (A) by separating capillary electrophoresis, the constituents of the admixture, leaving them within the capillary; (B) at one of the ends of the capillary obtained in th... | 02/21/2012 |
| 8012327 | Capillary electrophoresis apparatus and electrophoresis method An object of the present invention is to provide a capillary electrophoresis apparatus in which simultaneity can be ensured between sensitivity and data acquisition to decrease a pull-up signal while spectral data acquisition is eliminated in each capillary exchange... | 09/06/2011 |
| 7901557 | Method for multiplexed capillary electrophoresis signal cross-talk correction The present invention provides a simple method to correct cross-talk, after the data have been generated. Adjacent signals are simply subtracted from the original observed signal with a repeating process. The data processing is stopped when a predefined condition is... | 03/08/2011 |
| 7780831 | Assays for detection of von willebrand factor (vWF) multimers and for degradation of vWF by agents such as ADAMTS13 and related methods Methods of analyzing the electrophoretic mobility distribution of von Willebrand factor (vWF) multimers include providing a sample medium comprising a plurality vWF multimers. The vWF multimers are electrophoretically separated by electrohoretic mobility in the samp... | 08/24/2010 |
| 7758737 | Total analyte quantitation Methods for determining total analyte concentrations and amounts, especially in combination with analyte separations are provided. Microfluidic devices are used to separate analyte mixtures and detect the individual analytes. Signal areas are summed for each individ... | 07/20/2010 |
| 7670471 | Method and apparatus for analysis and sorting of polynucleotides based on size The invention relates to a microfabricated device and methods of using the device for analyzing and sorting polynucleotide molecules by size. ... | 03/02/2010 |
| 7638024 | Capillary electrophoresis method Disclosed is a capillary electrophoresis method for simultaneously electrophoresing an unknown sample and an internal standard material, determining an earliest peak as a peak derived from the internal standard material, and identifying the unknown sample on the bas... | 12/29/2009 |
| 7572357 | Chiral temperature gradient focusing A method and device are provided for concentrating and separating materials in fluids within a fluidic device having a fluid conduit such as a channel or capillary. The concentration is achieved by balancing the electrophoretic velocity of a material against the bul... | 08/11/2009 |
| 7497934 | System and method An analysis system for and method of enabling determination of the velocities of migrating objects and also classifying migrating objects into groups having a common constraint. In one aspect the present invention provides an analysis system for and method of enabli... | 03/03/2009 |
| 7438792 | Separation system with a sheath-flow supported electrochemical detector An electrochemical detector including side channels associated with a separation channel of a sample component separation apparatus is provided. The side channels of the detector, in one configuration, provide a sheath-flow for an analyte exiting the separation chan... | 10/21/2008 |
| 7439075 | Method and device for withdrawing suspended microparticles from a fluidic microsystem A method of discharging a fluid flow with suspended microparticles from a fluidic microsystem (10) is described, whereby the fluid flow converges with at least one output flow to form a discharge flow at the end of a discharge channel (14) of the micro... | 10/21/2008 |
| 7385210 | Device for spectroscopy using charged analytes A device for spectroscopy using charged analytes has an electron generator, which sends electrons through membrane into a charging chamber. The thermal strain of the membrane may be lowered significantly if a material is selected for the membrane which contains at l... | 06/10/2008 |
| 7368728 | Ionization source for mass spectrometry analysis A new ionization source named Surface Activated Chemical Ionization (SACI) has been discovered and used to improve the sensitivity of the mass spectrometer. According to this invention the ionization chamber of a mass spectrometer is heated and contains a physical n... | 05/06/2008 |
| 7359109 | Rear-viewable reflective display A novel reflective display system is described. The display system is viewable through the display backplane instead of the counterelectrode. Making the display viewable through the backplane allows use of a conducting elastomer as a counterelectrode which facilitat... | 04/15/2008 |
| 7344628 | Capillary electrophoresis-electrochemical detection microchip device and supporting circuits The present invention is a capillary electrophoresis device, comprising a substrate; a first channel in the substrate, and having a buffer arm and a detection arm; a second channel in the substrate intersecting the first channel, and having a sample arm and a waste ... | 03/18/2008 |
| 7341652 | Stationary capillary electrophoresis system A system and method for capillary electrophoresis are provided for analyzing a macromolecule prepared from a complex liquid mixture. In particular applications, methods and apparatus are provided for separating and analyzing a solution containing a denatured macromo... | 03/11/2008 |
| 7338808 | Method and apparatus for determining zeta potential using alternating current electric field and T channel Provided is a method for determining a zeta potential generated between a solid wall and a solution. The method includes (a) injecting an electrolyte solution into a first inlet of a T channel, which is provided with first and second inlet electrodes and a grounded ... | 03/04/2008 |
| 7332902 | Micro sensor for electrochemically monitoring residue in micro channels The present invention provides a micro sensor for monitoring the cleaning and drying processes for very high aspect ratio micro channels in dielectric films oriented parallel to the fluid-solid interface during the manufacture of ICs, MEMS and other micro-devices. T... | 02/19/2008 |
| 7329333 | Uniform laser excitation and detection in capillary array electrophoresis system and method A capillary electrophoresis system comprises capillaries positioned in parallel to each other forming a plane. The capillaries are configured to allow samples to migrate. A light source is configured to illuminate the capillaries and the samples therein. This causes... | 02/12/2008 |
| 7329388 | Electrophoresis apparatus having staggered passage configuration An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises a relatively large-bore transport capillary which intersects with a ... | 02/12/2008 |
| 7326326 | System and methods for electrophoretic separation of proteins on protein binding membranes Proteins can be rapidly separated to a high degree of resolution by electrophoresis on polymeric membranes that have high protein binding capacity. The electrophoretic separation is carried out in a low conductivity, water-miscible organic solvent buffer. The low co... | 02/05/2008 |
| 7318908 | Integrated nanotube sensor Integrated nanotube sensors are adapted for detecting various chemical and biological molecules. In one implementation, nanotube sensor arrays are formed as nano-electronic noses capable of such detection, and can be implemented in devices including carbon nanotube-... | 01/15/2008 |
| 7317111 | Green and orange fluorescent labels and their uses The present invention provides novel fluorescent compounds and covalent attachment chemistries which facilitate the use of these compounds as labels for ultrasensitive and quantitative fluorescent detection of low levels of biomolecules. In a preferred embodiment, t... | 01/08/2008 |
| 7316770 | Method of electrophoresis, electrophoresis apparatus and capillary array A method of electrophoresis, an electrophoresis apparatus and a capillary array in which a fluorescently labelled sample is supplied into capillaries in a capillary array constituted by a plurality of capillaries and including a sample supply portion, an electrophor... | 01/08/2008 |
| 7316700 | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties A lancing device, an embodiment of which controls the advancement and retraction of a lancet by monitoring the position of the lancet in conjunction with a lancet controller which incorporates a feedback loop for modulating the lancet driver to follow a predetermine... | 01/08/2008 |
| 7315667 | Propagating light to be sensed Light to be sensed is spreaded across an entry surface of a transmission structure with a laterally varying energy transmission function. For example, the light could be output from a stimulus-wavelength converter, provided through an optical fiber, or it could come... | 01/01/2008 |
| 7315021 | Charged droplet spray probe An improved sample introduction probe is disclosed for the production of ions from liquid sample solutions in an electrospray ion source. Nebulization of a liquid sample emerging from the end of an inner flow tube is pneumatically assisted by gas flowing from the en... | 01/01/2008 |
| 7309409 | Multi-channel bio-separation cartridge A bio-separation system using an efficient, compact, portable, interchangeable, reusable, recyclable, multi-channel cartridge, has integrated pre-aligned optics and an integrated reagent reservoir. The cartridge supports, for example, multiple capillaries for CE sep... | 12/18/2007 |
| 7307141 | Thermoresponsive sensor comprising a polymer solution Methods and apparatus for measuring and/or controlling the temperature on the surface or inside of micro chips are provided, including using thermally responsive polymers. ... | 12/11/2007 |
| 7301199 | Nanoscale wires and related devices The present invention relates generally to sub-microelectronic circuitry, and more particularly to nanometer-scale articles, including nanoscale wires which can be selectively doped at various locations and at various levels. In some cases, the articles may be singl... | 11/27/2007 |
| 7295311 | Methods and apparatus for electrophoretic mobility determination using phase light scattering analysis An apparatus and method are disclosed for determining electrophoretic mobility using scattering light phase analysis comprising emitting a laser light along a path and transmitting a first portion of the laser light and reflecting a second portion of the laser light... | 11/13/2007 |
| 7282126 | System and method for determining known DNA variants with temperature gradient electrophoresis The present invention relates to a method of determining the genotype of a sample polynucleotide having at least a first variant site. At least a portion of the sample polynucleotide is amplified to obtain first amplicons, the first amplicons including the first var... | 10/16/2007 |
| 7276446 | Planarizing solutions, planarizing machines and methods for mechanical or chemical-mechanical planarization of microelectronic-device substrate assemblies Planarizing solutions, planarizing machines and methods for planarizing microelectronic-device substrate assemblies using mechanical and/or chemical-mechanical planarizing processes. In one aspect of the invention, a microelectronic-device substrate assembly is plan... | 10/02/2007 |
| 7271895 | Fluorescent sensor on basis of multichannel structures Sensor for use in highly sensitive analytical devices for qualitative and quantitative analysis of natural waters and technology-related solutions, containing low concentrations of components determined. Design of a sensor provides for simplification and costs reduc... | 09/18/2007 |
| 7264702 | Total analyte quantitation Methods for determining total analyte concentrations and amounts, especially in combination with analyte separations are provided. Microfluidic devices are used to separate analyte mixtures and detect the individual analytes. Signal areas are summed for each individ... | 09/04/2007 |
| 7265349 | Method and apparatus for a multiple part capillary device for use in mass spectrometry The present invention provides a multiple part capillary for use in mass analysis instruments. Specifically, a multiple part capillary comprising at least two capillary sections joined with airtight seal by a union for use in mass spectrometry (particularly with ion... | 09/04/2007 |
| 7265348 | Apparatus for dispensing a sample in electrospray mass spectrometers The present invention relates to an apparatus to dispense a sample for subsequent electrospray ionisation (ESI) mass spectrometry (MS) analysis, to a method of fabricating such apparatus and to applications of such apparatus in biological and chemical analysis. The ... | 09/04/2007 |
| 7258775 | Method and device for the qualitative and/or quantitative analysis of a protein and/or peptide pattern of a liquid sample that is derived from the human or animal body The invention relates to a method for the qualitative and/or quantitative analysis of a protein and/or peptide pattern of a liquid sample that is derived from the human or animal body. The proteins and peptides of the liquid sample are separated by capillary electro... | 08/21/2007 |
| 7258776 | Capillary array assembly for loading samples from a device, and method A capillary array assembly is provided that can be used to inject samples into an electrophoresis device. The capillary array assembly can include an injection end that can be arranged to interface with output wells of a fluid processing device, for example, a micro... | 08/21/2007 |
