Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 8173001 | Method and apparatus for analysis and sorting of polynucleotides based on size The invention relates to a microfabricated device and methods of using the device for analyzing and sorting polynucleotide molecules by size. ... | 05/08/2012 |
| 8142630 | Electrophoresis devices and methods for focusing charged analytes Devices are provided for separating and focusing charged analytes, comprising a separation chamber and two or more electrodes, for example, an electrode array. A membrane separates the separation chamber and the electrodes. The separation chamber of the device is co... | 03/27/2012 |
| 8142631 | Particle focusing apparatus and method for focusing particles by using the same In a particle focusing apparatus and a method for focusing particles, the particle focusing apparatus includes a channel, a fixing member, a fluid feeding portion and a power supply. The channel has first and second ends and extends substantially in a line. The fixi... | 03/27/2012 |
| 8105471 | Nanofluidics for bioseparation and analysis The invention includes nanochannel devices and methods for using such nanochannel devices for separating molecules, ions and biomolecules. The nanochannel devices have at least one nanochannel through which fluid can move, wherein ionic double layers form in the flu... | 01/31/2012 |
| 8083915 | Methods for forming small-volume electrical contacts and material manipulations with fluid microchannels A microfabricated device employing a bridging membrane and methods for electrokinetic transport of a liquid phase biological or chemical material using the same are described. The bridging membrane is deployed in or adjacent to a microchannel and permits either ioni... | 12/27/2011 |
| 8080144 | Gradient elution electrophoresis A method for performing electrophoretic separation of ionic compounds which involves varying a bulk fluid flow though a separation path into which ionic species are continuously introduced and separated. The method can also include the introduction of a leading elec... | 12/20/2011 |
| 7988840 | Method for continuous particle separation using obstacle arrays asymmetrically aligned to fields The present invention relates to methods and devices for separating particles according to size. More specifically, the present invention relates to a microfluidic method and device for the separation of particles according to size using an array comprising a networ... | 08/02/2011 |
| 7988839 | Capillary electrophoresis systems and methods An embodiment of the invention is directed to a capillary electrophoresis apparatus comprising a plurality of separation micro-channels. A sample loading channel communicates with each of the plurality of separation channels. A driver circuit comprising a plurality ... | 08/02/2011 |
| 7955575 | Microfluidic surfaces A microfluidic device comprising a set of one or more, preferably more than 5, covered microchannel structures manufactured in the surface of a planar substrate. The device is characterized in that a part surface of at least one of the microchannel structures has a ... | 06/07/2011 |
| 7906001 | Method for separating proteins by capillary electrophoresis and buffer compositions for capillary electrophoresis The invention concerns a free solution capillary electrophoresis method at alkaline pH for the analysis of samples comprising protein constituents including a lipoprotein constituent or constituents, characterized in that it comprises at least one step in which the ... | 03/15/2011 |
| 7887686 | Method for analyzing haemoglobin by capillary electrophoresis, a kit for capillary electrophoresis, and use of a flow inhibitor in said method The invention concerns a method for free solution capillary electrophoresis at an alkaline pH to analyze samples comprising haemoglobin, in which the sample is passed through a capillary containing an analysis buffer, comprising at least one step in which the sample... | 02/15/2011 |
| 7857955 | Coated capillary electrophoresis tubes and system The invention is directed to a capillary tube for electrophoresis that has a positively charged coating on the capillary inner surface that prevents positively charged analytes from adsorbing to the inner capillary surface. The capillary tube has an inner surface th... | 12/28/2010 |
| 7850834 | Electrophoresis method using capillary plate In an electrophoresis method, a capillary plate having a capillary channel is maintained in a predetermined temperature to be processed, and a sample is filled into the capillary channel. A solution is prepared to have a temperature substantially the same as the pre... | 12/14/2010 |
| 7846314 | Handling a plurality of samples A method for handling samples in a microfluidic system is described. The microfluidic system includes an injection channel fluidically coupled to an injection point adapted for injecting an amount of fluid, a first sample well containing a first sample, the first sa... | 12/07/2010 |
| 7837848 | Bidimensional separation by means of capillary electrophoresis carried out in a single capillary A method for separating the constituents of a mixture M by electrophoresis in a single capillary includes (A) separating compounds of the mixture M in a single capillary according to the capillary electrophoresis technique; (B) isolating a fraction F of the compound... | 11/23/2010 |
| 7833399 | Concentration method of fine particle dispersion and concentration apparatus of fine particle dispersion The present invention provides a concentration method of a fine particle dispersion containing fine particles to be electrophoretically migrated, for concentrating the fine particle dispersion by allowing the fine particle dispersion to flow in a laminar flow in a c... | 11/16/2010 |
| 7820023 | Preconcentration interface coupling liquid chromatography to capillary electrophoresis An arrangement for two-dimensional separation of a complex analyte mixture is provided comprising a first separation device for the separation in a first dimension and a second device for the separation in the second dimension. In the area of the interface between t... | 10/26/2010 |
| 7790007 | Electrophoresis chip, electrophoresis apparatus, and method for analyzing a sample A sample which contains protein is stably maintained in a liquid state during electrophoresis. Electrophoresis chip 1 includes substrate 2, channels 5a to 5d which is provided on surface 3 of substrate 2 and wh... | 09/07/2010 |
| 7736481 | Electrophoresis device and electrophoresis method To reduce the elongation of the migration time for the first electrophoresis cycle in successive electrophoresis cycles and improve the reliability of electrophoresis analysis. The present invention relates to making the condition of a migration medium at the start ... | 06/15/2010 |
| 7731827 | Method for capturing charged molecules traveling in a flow stream The invention relates to a method for capturing charged molecules of interest traveling in an electrolyte flow stream through an electrically non-conductive channel, comprising at least one anode and at least one cathode individually separated from said channel, but... | 06/08/2010 |
| 7708873 | Induced-charge electro-osmotic microfluidic devices This invention provides devices and apparatuses comprising the same, for efficient pumping and/or mixing of relatively small volumes of fluid. Such devices utilize nonlinear electrokinetics as a primary mechanism for driving fluid flow. Methods of cellular analysis ... | 05/04/2010 |
| 7708872 | Actuator in a microfluidic system for inducing electroosmotic liquid movement in a micro channel The present invention describes an actuator in a microfluidic system for inducing an electroosmotic liquid movement in a microchannel. ... | 05/04/2010 |
| 7678254 | Microchip processing method and apparatus The processing apparatus for microchips, each at least having a main flow path performing migration of a sample for analysis inside a sheet-like member, comprises a holding part holding microchips so that the multiple main flow paths are provided; a pretreatment par... | 03/16/2010 |
| 7645369 | Separation method and device for protein mixtures A separation device and a separation method for biomolecular sample material and in particular protein mixtures. For this purpose a separation element 10 for the two-dimensional and preferable electrophoretic separation of components of the sample material is... | 01/12/2010 |
| 7625475 | Nanotube fluid pump A microfluidic pump has an outer housing such as a capillary tube, a nanotube, and an ionic fluid or alcohol. The nanotube is placed inside the capillary tube, and the capillary tube is filled with the ionic fluid or alcohol. A voltage source is connected to the nan... | 12/01/2009 |
| 7578916 | Emulsions of ionic liquids The present teachings provide emulsions using ionic liquids for separation of biomolecules and related methods, compositions, and devices. ... | 08/25/2009 |
| 7578915 | Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis A modular multiple lane or capillary electrophoresis (chromatography) system that permits automated parallel separation and comprehensive collection of all fractions from samples in all lanes or columns, with the option of further on-line automated sample fraction a... | 08/25/2009 |
| 7465381 | Electrokinetic molecular separation in nanoscale fluidic channels A method for separation of mixtures in fluidic systems through electrokinetic transport by use of nanochannels when the fluidic systems approach the size of an electrical double layer, thereby allowing separation based on charge. The disclosed apparatus comprises a ... | 12/16/2008 |
| 7459068 | Multi-capillary electrophoresis apparatus A multi-capillary electrophoresis apparatus is provided for reducing errors during analysis caused by fluctuations in electrophoresis time among plural capillaries of the apparatus. The multi-capillary electrophoresis apparatus can contain a multi-capillary array th... | 12/02/2008 |
| 7459069 | Electrophoresis device and the use thereof The invention relates to a device for electrophoretically separating molecules. The inventive device comprises: at least one plate having a top side and an underside; a first separating channel provided for receiving at least one first separating medium; at least on... | 12/02/2008 |
| 7439075 | Method and device for withdrawing suspended microparticles from a fluidic microsystem A method of discharging a fluid flow with suspended microparticles from a fluidic microsystem (10) is described, whereby the fluid flow converges with at least one output flow to form a discharge flow at the end of a discharge channel (14) of the micro... | 10/21/2008 |
| 7425254 | Fractionation of macro-molecules using asymmetric pulsed field electrophoresis A method and apparatus for fractionation of charged macro-molecules such as DNA is provided. DNA solution is loaded into a matrix including an array of obstacles. An alternating electric field having two different fields at different orientations is applied. The alt... | 09/16/2008 |
| 7422669 | Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream A microfluidic device and method for forming and dispensing minute volume segments of a material are described. In accordance with the present invention, a microfluidic device and method are provided for spatially confining the material in a focusing element. The de... | 09/09/2008 |
| 7413642 | Material separation device A separating device for use in separating electrically charged components, e.g., by electrophoresis, comprises a channel branched at a branch point to provide a main feed channel (105) connected to at least two subsidiary channels (110, 115). In use, d... | 08/19/2008 |
| 7410559 | Electrophoresis methods A separation carrier comprising β-1,3-glucan and/or methyl cellulose; a running buffer comprising the separation carrier; a method of capillary electrophoresis or microchip electrophoresis, wherein a sample comprising macromolecular compounds is run in the presence... | 08/12/2008 |
| 7396444 | Device to operate a laboratory microchip In a device to operate and handle a laboratory microchip to chemically process or analyze substances, the microchip is on a chip holder (41) that is part of a first assembly (42). The first assembly (42) also has an optical device (43) fo... | 07/08/2008 |
| 7384525 | Electrophoretic analysis system having in-situ calibration An electrophoretic system having a plurality of separation lanes is provided with an automatic calibration feature in which each lane is separately calibrated. For each lane, the calibration coefficients map a spectrum of received channel intensities onto values ref... | 06/10/2008 |
| 7368728 | Ionization source for mass spectrometry analysis A new ionization source named Surface Activated Chemical Ionization (SACI) has been discovered and used to improve the sensitivity of the mass spectrometer. According to this invention the ionization chamber of a mass spectrometer is heated and contains a physical n... | 05/06/2008 |
| 7364647 | Laminated flow device A laminated flow device comprises a porous material encapsulated within bonding material. The porous material forms a flow path and the bonding material forms an enclosure surrounding the flow path. Micro-components, such as capillaries, electrodes, reservoirs, brid... | 04/29/2008 |
| 7361259 | Capillary array and electrophoresis apparatus, and method A capillary electrophoresis device including a capillary array, and a method of manufacturing the capillary array, are provided. During the manufacture of the capillary array, a plurality of capillaries are arranged in a substantially parallel arrangement and are fi... | 04/22/2008 |