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...Daniel Webster invented a "bull plow" to pull out tree stumps. It didn't catch on because it was huge and required four oxen to pull it!
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| Number | Title | Issue Date |
| 8173000 | Active matrix device and method of driving the same An active matrix electrowetting on dielectric (AM-EWOD) device which includes a plurality of array elements configured to manipulate one or more droplets of fluid on an array, each of the array elements including a corresponding array element circuit. Each array ele... | 05/08/2012 |
| 8163150 | Electrowetting dispensing devices and related methods A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing... | 04/24/2012 |
| 8088265 | Cell separation A process for separating a cell type from a mixture of cell types by electrophoresis comprising providing a sample containing a mixture of cell types to a sample chamber of membrane-based electrophoresis apparatus adapted to separate cells and applying an electric p... | 01/03/2012 |
| 8075754 | Electrowetting pumping device and use for measuring electrical activity The invention relates to a method for pumping through an orifice (30, 31) of a first substrate (1), a first volume of liquid (2) in contact with a first hydrophobic surface of said substrate, wherein a pressure variation between the first volume... | 12/13/2011 |
| 8021530 | Method for separation of chemical substances and/or particles, device and its use Electric fields are applied parallel to and/or vertical to the interfaces on adjacent microfluid lamellae made of nonmiscible media containing said biomolecules and bioparticles to which they have different physico-chemical affinities in order to separate biomolecul... | 09/20/2011 |
| 7959779 | Macroscopically manipulable nanoscale devices made from nanotube assemblies This invention relates generally to cutting single-wall carbon nanotubes (SWNT). In one embodiment, the present invention provides for preparations of homogeneous populations of short carbon nanotube molecules by cutting and annealing (reclosing) the nanotube pieces... | 06/14/2011 |
| 7938945 | Microfluidic device for electrochemically regulating pH of fluid and method of regulating pH of fluid using the microfluidic device A microfluidic device includes; an ion exchange membrane, an anode chamber one side of which contacts a surface of the ion exchange membrane, wherein the anode chamber further includes a ladder-shaped anode and an anode support part, and a cathode chamber, one side ... | 05/10/2011 |
| 7931789 | Device for charging separation buffer liquid to microchip, and microchip processing device equipped with the charging device, electrophoresis method in capillary channel and its microchip processing device In a separation buffer solution filling device, a microchip is arranged such reservoirs are opened on a surface on respective ends of channels including at least a main separation channel in which analysis is performed while a solution moves inside a plate-like memb... | 04/26/2011 |
| 7931790 | Methods for forming small-volume electrical contacts and material manipulations with fluidic microchannels A microfabricated device employing a bridging membrane and methods for electrokinetic transport of a liquid phase biological or chemical material using the same are described. The bridging membrane is deployed in or adjacent to a microchannel and permits either ioni... | 04/26/2011 |
| 7922886 | Drop dispenser device A liquid dispensing device includes first and second substrates, with the first substrate including an opening for introduction of a fluid, and the second substrate including a multiplicity of electrodes. The device includes a transfer electrode, located at least pa... | 04/12/2011 |
| 7922885 | Device for transporting liquid and system for analyzing In a device for transporting liquid, liquid to be transported is enclosed by an oil droplet, which is fractionated with air, for manipulation. Moreover, as a method for supplying liquids wherein a plurality of liquids are enclosed by an oil droplet sequentially and ... | 04/12/2011 |
| 7918979 | Entropic trapping and sieving of molecules Nanofluidic entropic traps, comprising alternating thin and thick regions, sieve small molecules such as DNA or protein polymers and other molecules. The thick region is comparable or substantially larger than the molecule to be separated, while the thin region is s... | 04/05/2011 |
| 7909973 | Methods for forming small-volume electrical contacts and material manipulations with fluidic microchannels A microfabricated device employing a bridging membrane and methods for electrokinetic transport of a liquid phase biological or chemical material using the same are described. The bridging membrane is deployed in or adjacent to a microchannel and permits either ioni... | 03/22/2011 |
| 7906248 | Connecting structure, flow path control section, fuel cell-type power generation device, and electronic apparatus Disclosed herein is a connecting structure for connecting to an electro-osmotic flow pump with electrodes formed on both surfaces of electro-osmotic material, including: a first liquid absorber for absorbing liquid; and a second liquid absorber for absorbing the liq... | 03/15/2011 |
| 7883612 | Microfluidic device for electrochemically regulating the pH of a fluid therein using semiconductor doped with impurity and method of regulating the pH of a fluid in a microfluidic device using the same Provided is a microfluidic device for electrochemically regulating the pH of a fluid comprising: a cathode substrate; an anode substrate facing the cathode substrate and forming a reaction chamber with the cathode substrate; and a nonconductor which forms a boundary... | 02/08/2011 |
| 7875160 | Method for controlling a communication between two areas by electrowetting, a device including areas isolatable from each other and method for making such a device Device for displacing drops of liquid by electrowetting, and a method for isolating two areas delimited by at least one wall including a step for: placing by electrowetting, in an aperture of said wall, a substance capable of react... | 01/25/2011 |
| 7875159 | Electrokinetic pump having capacitive electrodes An electrokinetic pump achieves high and low flow rates without producing significant gaseous byproducts and without significant evolution of the pump fluid. A first feature of the pump is that the electrodes in the pump are capacitive with a capacitance of at least... | 01/25/2011 |
| 7842175 | Electrophoresis The invention relates to a method for separating a target for measurement utilizing electrophoresis, particularly capillary electrophoresis efficiently in high sensitivity and in a short period of time. It also relates to a method for measuring said target separated... | 11/30/2010 |
| 7833398 | Length-dependent recoil separation of long molecules Separation of long molecules by length is obtained by forcing such molecules to traverse a boundary between a low free-energy region and a high free-energy region. In one embodiment, the high free-energy region is a dense pillar region or other structure formed on a... | 11/16/2010 |
| 7803261 | Method to deposit particles on charge storage apparatus with charge patterns and forming method for charge patterns The present invention discloses a method to deposit particles on a charge storage apparatus with charge patterns and a forming method for charge patterns. The forming method for charge patterns includes providing the charge storage apparatus having an electrically c... | 09/28/2010 |
| 7780830 | Electro-wetting on dielectric for pin-style fluid delivery A method of delivering fluid can include using electro-wetting effects to pick-up, transport, and/or deliver discrete volumes of fluid. Voltage can be applied across a fluid contact area having a conductive substrate and a dielectric material with an outer surface. ... | 08/24/2010 |
| 7767069 | Method for controlling the contact angle of a droplet in electrowetting and an apparatus using the droplet formed thereby A method for controlling the hydrophilic droplet using the electrowetting principle is disclosed. More specifically, the present invention provides a method for increasing the change of the contact angle in the interface that is formed between the hydrophilic drople... | 08/03/2010 |
| 7736480 | Multi-dimensional electrophoresis method An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises a relatively large-bore transport capillary which intersects with a ... | 06/15/2010 |
| 7731826 | Controlled translocation of a polymer in an electrolytic sensing system An electrolytic sensing system for measuring a blocking signal allows for controlled translocation of a molecule, such as DNA, through a fluid channel. A substantially constant electric field supplied by a DC source is applied across the fluid channel and induces tr... | 06/08/2010 |
| 7718046 | Micellar gradient focusing A method and device are provided for affinity gradient focusing for directing at least one analyte in a solution containing a pseudostationary phase and located in a channel such as a capillary or a microchannel. The method includes establishing a steady-state spati... | 05/18/2010 |
| 7708871 | Nanodevice for controlled charged particle flow and method for producing same The present invention relates to an apparatus having a nanodevice (1) for controlling the flow of charged particles in an electrolyte. Such apparatus comprises an electrolytic bath container (2) divided by a polymeric membrane foil (3) into a fi... | 05/04/2010 |
| 7708870 | Method of electrophoresing protein To provide an electrophoresis method being capable of rapidly analyzing a protein in a native state without carrying out a heat-denaturing pretreatment step, and having even higher sensitivity. The electrophoresis method of the present invention is useful for proteo... | 05/04/2010 |
| 7704360 | Devices and methods for separating sample constituents Devices and methods for separating sample constituents are provided. The subject devices are characterized by having a fluid flow path with at least one electrophoretic separation element positioned at a region thereof. The separation element includes an element for... | 04/27/2010 |
| 7691244 | Microfluidic pumps and mixers driven by induced-charge electro-osmosis This invention provides devices and apparatuses comprising the same, for the mixing and pumping of relatively small volumes of fluid. Such devices utilize nonlinear electrokinetics as a primary mechanism for driving fluid flow. Methods of cellular analysis and high-... | 04/06/2010 |
| 7651598 | Arbitrary and simultaneous control of multiple objects in microfluidic systems In a microfluidic device, respective motion of a plurality of objects along corresponding trajectories is achieved by determining a force field, such as an underlying fluid flow which, when applied to the plurality of object, moves each object along its correspondin... | 01/26/2010 |
| 7645368 | Orientation independent electroosmotic pump According to some embodiments, a method, system, and apparatus for providing an orientation independent electroosmotic pump. In some embodiments, the method includes an anode and a cathode at different electrical potentials, the anode and cathode are each sealed in ... | 01/12/2010 |
| 7625474 | Method for a microfluidic weaklink device The present invention relates to an electrokinetic (EK) pump capable of creating high pressures electroosmotically, and capable of retaining high pressures. Both pressure creation and retention are accomplished without the need for moving parts. The EK pump uses a p... | 12/01/2009 |
| 7611614 | Method of cell capture Embodiments of methods and devices are disclosed for the manipulation (e.g., concentration, purification, capture, trapping, location, transfer) of analytes, e.g., biomolecules, with respect to analyte-containing solutions, using one or more electric fields. ... | 11/03/2009 |
| 7597790 | Flow control systems A flow controller which uses a combination of hydrostatic pressure and electroosmotic flow to control the flow of a fluid. A driving fluid (1204) whose flow rate is dependent on both hydrostatic pressures and electroosmotic flow can be used (a) directly as a ... | 10/06/2009 |
| 7569129 | Methods for manipulating droplets by electrowetting-based techniques Methods are provided for manipulating droplets. The methods include providing the droplet on a surface comprising an array of electrodes and a substantially co-planer array of reference elements, wherein the droplet is disposed on a first one of the electrodes, and ... | 08/04/2009 |
| 7537680 | Mixing reactions by temperature gradient focusing A method is provided for observing mixing interactions and reactions of two materials in a fluid. The method in one form provides for concentrating by balancing electrophoretic velocities of a material against the bulk flow of fluid in the presence of a temperature ... | 05/26/2009 |
| 7537679 | Materials classifier, method of using, and method of making The present invention relates to a method of classifying charged molecules such as proteins for quantitative analysis. An analyte solution of the molecules is subjected to separational forces may be fluid drag and electrophoretic force in opposition. The analyte sol... | 05/26/2009 |
| 7531072 | Device for controlling the displacement of a drop between two or several solid substrates A device for reversibly displacing at least one volume of liquid under the effect of an electrical control, including first electrically conductive device, second electrically conductive device, and a device for inducing a reversible displacement of a volume of liqu... | 05/12/2009 |
| 7517440 | Electrokinetic delivery systems, devices and methods A method of pumping fluid including the steps of providing an electrokinetic pump comprising a pair of double-layer capacitive electrodes having a capacitance of at least 10−2 Farads/cm2 and being connectable to a power source, a porous diele... | 04/14/2009 |
| 7510637 | Microelectronic arrays for cell-based functional genomics/high throughput phenotyping by electrokinetic assembly An electrochemical apparatus 1 permits electric-field-assisted fluidic assembly of objects 2 on a patterned silicon substrate 11 by means of electrical addressing. Charged objects 2 such as beads and live cells are moved electrokineticall... | 03/31/2009 |
