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| Number | Title | Issue Date |
| 7410709 | Bio-battery A bio-battery includes a biomolecular energy source, a first electrode and a second electrode. In some configurations, a bio-battery may also include a first cell containing the first electrode and the biomolecular energy source, and a second cell having a reducible... | 08/12/2008 |
| 7393448 | Method of binding a compound to a sensor surface The present invention relates to a method of non-covalently binding a compound to a sensor surface. The method comprises adsorbing a hydrophobin-like substance to at least a part of the sensor surface, such as an electrode. The invention further provides a sensor ha... | 07/01/2008 |
| 7371247 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the pe... | 05/13/2008 |
| 7364886 | Chemical sensor enhanced by direct coupling of redox enzyme to conductive surface The invention provides a method, apparatus and system for detecting electrochemical oxidoreduction activity mediated by a redox enzyme at a site remote from the enzyme. In one embodiment, the method comprises immobilizing the redox enzyme on a first region of a cond... | 04/29/2008 |
| 7364647 | Laminated flow device A laminated flow device comprises a porous material encapsulated within bonding material. The porous material forms a flow path and the bonding material forms an enclosure surrounding the flow path. Micro-components, such as capillaries, electrodes, reservoirs, brid... | 04/29/2008 |
| 7351770 | Ionic hydrophilic high molecular weight redox polymers for use in enzymatic electrochemical-based sensors Ionic hydrophilic high molecular weight redox polymers for use in enzymatic electrochemical-based sensors include a hydrophilic polymer (such as a hydrophilic polymer backbone) with ionic portions (e.g., cationic monomers incorporated in the hydrophilic polymer back... | 04/01/2008 |
| 7341830 | Method and reagent system having a non-regenerative enzyme-coenzyme complex The invention relates to a method and reagent system for detecting an analyte in a sample by means of an enzymatic reaction, involving the use of an enzyme-coenzyme complex as a stoichiometric reaction partner for the analyte present in the sample. ... | 03/11/2008 |
| 7331931 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generato... | 02/19/2008 |
| 7316700 | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties A lancing device, an embodiment of which controls the advancement and retraction of a lancet by monitoring the position of the lancet in conjunction with a lancet controller which incorporates a feedback loop for modulating the lancet driver to follow a predetermine... | 01/08/2008 |
| 7311812 | Biosensor A biosensor for determining the concentration of an analyte in a biological sample. The biosensor comprises a support, a reference electrode or a counter electrode or both a reference and a counter electrode disposed on the support, a working electrode disposed on t... | 12/25/2007 |
| 7291117 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a voice coil based penetrating member driver. A plurality of penetrating members are included. A transport mechanism is configured to... | 11/06/2007 |
| 7287318 | Biosensor A biosensor is provided that comprises a plate element with a pre-determined reaction zone and a recess positioned adjacent to the reaction zone. The biosensor also comprises a reagent that is positioned on the reaction zone. In preferred embodiments, the recess cir... | 10/30/2007 |
| 7283866 | Needle having multiple electrodes Embodiments of the invention generally relate to needles having more than one electrode and which are particularly suited for use in electromyography. One embodiment relates to a tripolar needle having three concentric electrodes. The tripolar needle is formed by pr... | 10/16/2007 |
| 7258693 | Device and method for variable speed lancet A method of penetrating tissue is provided. The method comprises using a lancet driver to advance a lancet into the tissue; advancing the lancet at a first desired velocity in a first layer of tissue; advancing the lancet at a second desired velocity in a second lay... | 08/21/2007 |
| 7249490 | Isolated gas sensor configuration A gas sensor assembly detects a constituent in a gaseous stream. The assembly comprises: (a) a mounting surface, (b) a sensor mounted on the mounting surface and sensor capable of generating a detectable signal in the presence of the constituent, and (c) an enclosin... | 07/31/2007 |
| 7244265 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a drive force generator and a penetrating member operatively coupled to the force generator. The force generator moves the member alo... | 07/17/2007 |
| 7238442 | Biological fuel cell and methods A fuel cell has an anode and a cathode with anode enzyme disposed on the anode and cathode enzyme is disposed on the cathode. The anode is configured and arranged to electrooxidize an anode reductant in the presence of the anode enzyme. Likewise, the cathode is conf... | 07/03/2007 |
| 7232451 | Method and apparatus for penetrating tissue A skin penetrating system has a housing member and a plurality of penetrating members positioned in the housing member. A tissue stabilizing device is coupled to the housing member. A user interface is configured to relay at least one of, skin penetrating performanc... | 06/19/2007 |
| 7229458 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of cartridges each with a distal port and a proximal port. A plurality of penetrating members are provided, each coupled to a cartridge and having a sharpened distal tip and a shaft portion slidably disposed within th... | 06/12/2007 |
| 7226461 | Method and apparatus for a multi-use body fluid sampling device with sterility barrier release A device for use with a gripper is provided. A cartridge is provided that defines a plurality of cavities. A plurality of penetrating members are at least partially contained in the cavities of the cartridge. The penetrating members are slidably movable to extend ou... | 06/05/2007 |
| 7198606 | Method and apparatus for a multi-use body fluid sampling device with analyte sensing A device for use with a penetrating member driver to penetrate tissue is provided. A plurality of penetrating members are coupled to a single cartridge and are operatively couplable to the penetrating member driver. The penetrating members are movable to extend radi... | 04/03/2007 |
| 7198708 | Electrochemical biosensor An electrochemical biosensor for quantifying one or more redox species in a liquid sample comprising a background electrochemical activity, wherein said biosensor comprises: (i) an electrode system; (ii) a filter m... | 04/03/2007 |
| 7195704 | Determination of sample volume adequacy in biosensor devices Methods and systems are provided for determining whether a volume of biological sample is adequate to produce an accurate electrochemical analyte concentration measurement. Certain such methods and systems provide the additional function of compensating for a sample... | 03/27/2007 |
| 7192766 | Sensor containing molded solidified protein A method for formulating and immobilizing a protein and a protein matrix formed by the method. The protein matrix preparation method results in a physically and chemically stable protein matrix that has low swelling, non-leaching, high activity, and high mechanical ... | 03/20/2007 |
| 7192450 | Porous membranes for use with implantable devices A membrane for implantation in soft tissue comprising a first domain that supports tissue ingrowth, disrupts contractile forces typically found in a foreign body response, encourages vascularity, and interferes with barrier cell layer formation, and a second domain ... | 03/20/2007 |
| 7175746 | Polymer based enzyme electrode for estimation of cholesterol and process for preparation thereof A polymer based enzyme electrode useful for estimation for cholesterol is disclosed. The electrode has an ion-doped layer to increase the conductivity of the poly pyrrole layer. The ion doping is achieved by incorporating dodecyl benzene sulphonate (DBS) in the poly... | 02/13/2007 |
| 7146202 | Compound material analyte sensor A sensing element adapted to, at least in part, be inserted into a mammalian body. The sensing element is made up of a core of a structurally robust metal and a plated portion made of an electrochemically active metal conjoined to at least a portion of the core. Thi... | 12/05/2006 |
| 7146203 | Implantable biosensor and methods of use thereof Provided herein is a stabilized oxygen transport matrix that includes a reversible oxygen binding protein, such as hemoglobin, immobilized throughout the stabilized oxygen transport matrix. The stabilized oxygen transport matrix is used to transport oxygen and can b... | 12/05/2006 |
| RE39390 | Biosensor There is provided a cholesterol sensor with high-accuracy and excellent response, whose object to be measured is whole blood, where plasma with which is obtained by filtering out hemocytes therein filtered in blood can rapidly reach an electrode system. In a biose... | 11/14/2006 |
| 7135100 | Amperometric sensor An amperometric sensor suitable for determining the concentration of hydrogen peroxide in a sample, said sensor comprising a ferricyanide compound which, in reduced form, functions as a mediator specific to hydrogen peroxide. ... | 11/14/2006 |
| 7134999 | Optimized sensor geometry for an implantable glucose sensor An implantable sensor for use in measuring a concentration of an analyte such as glucose in a bodily fluid, including a body with a sensing region adapted for transport of analytes between the sensor and the bodily fluid, wherein the sensing region is located on a c... | 11/14/2006 |
| 7112265 | Disposable test strips with integrated reagent/blood separation layer An improved disposable glucose test strip for use in a test meter of the type which receives a disposable test strip and a sample of blood from a patient and performs an electrochemical analysis using a non-conductive integrated reagent/blood separation layer (17... | 09/26/2006 |
| 7108778 | Electrochemical sensors including electrode systems with increased oxygen generation The present invention relates generally to systems and methods for increasing oxygen generation in electrochemical sensors in order to overcome the oxygen limitations. The preferred embodiments employ electrode systems with at least two electrodes in relatively clos... | 09/19/2006 |
| 7059206 | Aquatic passive sampling device and methods for its use An aquatic passive sampling device is disclosed comprising a diffusion-limiting membrane and a receiving phase itself comprising an immobilised solid phase material supported by a solid support. The solid support and membrane features enable the device to be adapted... | 06/13/2006 |
| 7056726 | membrane for encapsulation chamber of cells producing at least a biologically active substance and bioartificial organ comprising same The invention concerns a semipermeable chamber for encapsulation of cells producing at least a biological substance of interest, characterised in that it consists of a porous polycarbonate biocompatible film modified at the surface by generated polar sites and cover... | 06/06/2006 |
| 7041068 | Sampling module device and method A tissue penetration device and method of using same that may include a lancet module or sampling module. The sampling module may optionally be in a cartridge configuration and include sampling and analyzing functions, which may be integrated. ... | 05/09/2006 |
| 7025774 | Tissue penetration device A tissue penetration device and method of using same. The tissue penetration device may optionally include sampling and analyzing functions, which may be integrated. An embodiment provides control of a lancet used for sampling blood. Electric field coils or solenoid... | 04/11/2006 |
| 6932894 | Biosensor membranes composed of polymers containing heterocyclic nitrogens Novel membranes comprising various polymers containing heterocyclic nitrogen groups are described. These membranes are usefully employed in electrochemical sensors, such as amperometric biosensors. More particularly, these membranes effectively regulate a flux of an... | 08/23/2005 |
| 6931327 | System and methods for processing analyte sensor data Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the ... | 08/16/2005 |
| 6776888 | Biosensor The present invention provides a biosensor that enables highly-accurate measurement of a sample solution including a solid component like hemocytes and has a little variation in response. The biosensor includes: an insulating base plate, an electrode system having a... | 08/17/2004 |
