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| Number | Title | Issue Date |
| 6030960 | Method of treating hepatitis virus infections A method of treating hepatitis virus infection is disclosed. The method comprising administering to a human subject in need of such treatment an effective hepatitis virus-combatting amount of an alkyl lipid or alkyl lipid derivative.... | 02/29/2000 |
| 5770584 | Method of treating hepatitis virus infections A method of treating hepatitis virus infection is disclosed. The method comprising administering to a human subject in need of such treatment an effective hepatitis virus-combatting amount of an alkyl lipid or alkyl lipid derivative.... | 06/23/1998 |
| 5000880 | Novel process for producing phosphatidylcholine derivatives Glycero-phosphatidylcholine is acylated with a higher fatty acid anhydride in the presence of a special organic solvent in the absence of a catalyst.... | 03/19/1991 |
| 4994581 | Phosphoric esters A novel phosphoric ester of the formula (I) ##STR1## wherein, Z represents the following radicals ##STR2## useful as modifiers for amino acids, peptides and proteins which are easily decomposable in living bodies.... | 02/19/1991 |
| 4981989 | Antihypertensive phosphate derivatives and intermediates thereof Antihypertensive phosphate derivatives having the following formula are described: ##STR1## wherein X is selected from one or more of: (a) C1 -C24 branched or straight chain alkyl; (b) C1 -C24 branched or s... | 01/01/1991 |
| 4963527 | Phospholipid complexes of extracts of vitis vinifera, their preparation process and pharmaceutical and cosmetic compositions containing them Complexes resulting from the reaction of phospholipids, synthetic or of vegetable or animal origin, with flavonoids extracted from Vitis vinifera, their use in therapeutics and in cosmetics.... | 10/16/1990 |
| 4962096 | Heterocyclic glycerol derivatives and their use as anti-hypertensive agents A novel glycerol derivative which is effective to reduce blood pressure has the formula: ##STR1## wherein R1 is an alkyl group having 10-22 carbon atoms, R2 is lower acyl, benzoyl, aryl, mono-, di- or triarylalkyl, alkyl, cycloa... | 10/09/1990 |
| 4959357 | Phospholipase A2 inhibitor Potent, specific inhibitors of phospholipase A2 are disclosed which are compounds of the formula: ##STR1## wherein A is R1 CO2 or OH, B is R2 CO2 or OH, D is R3 CO2 or OH an... | 09/25/1990 |
| 4939127 | Antihypertensive phosphate derivatives Antihypertensive phosphate derivatives having the following formula are described: ##STR1## wherein W is selected from the group consisting of methyl and phenyl optionally substituted with C1 -C3 alkyl, C1 -C3 | 07/03/1990 |
| 4916249 | Glycero-3(2)-phospho-L-serine derivatives and salts thereof The invention relates to novel glycero-3(2)phospho-L-serine derivatives of the general formula ##STR1## in which A represents unsubstituted or substituted (C5-C30) alkoxy, or unsubstituted or substituted (C5-C30) alkenoxy, whereby a double bond of ... | 04/10/1990 |
| 4900731 | Antihypertensive phosphate derivatives Antihypertensive phosphate derivatives are described having the following formula: ##STR1## wherein n is an integer 1 or 2; m is an integer 1 or 2, and the sum of n and m must be 3; X is selected from the group consisting of C1 -C | 02/13/1990 |
| 4897385 | Antihypertensive phosphate derivatives Antihypertensive phosphate derivatives having the following formula are described: ##STR1## wherein X is selected from the group consisting of a phenyl radical substituted at any position with a C1 -C20 branched or straight ... | 01/30/1990 |
| 4897382 | Organic amide compounds derived from nitrogenous lipids Organic amide compounds of the formula ##STR1## wherein R1 --CO is a residue of a carboxylic acid with the proviso that the carboxylic acid is not a natural fatty acid normally bound to nitrogen of nitrogenous lipids, R2 is a hy... | 01/30/1990 |
| 4897381 | Organic amide compounds derived from nitrogenous lipids Organic amide compounds of the formula ##STR1## wherein R1 --CO is a residue of a carboxylic acid with the proviso that the carboxylic acid is not a natural fatty acid normally bound to nitrogen of nitrogenous lipids, R2 is a hy... | 01/30/1990 |
| 4894367 | Antihypertensive phosphate derivatives Antihypertensive phosphate derivatives having the following formula: ##STR1## wherein X is selected from one or more of C1 -C24 alkyl; C1 -C24 alkoxy; n and m are integers from 0 to 25 and the sum of which ... | 01/16/1990 |
| 4883816 | Antihypertensive derivatives Antihypertensive sulfonyl derivatives having the following formula are described: ##STR1## where R" is a C2 -C20 alkyl group, R"1 is a C1 to C4 alkyl group, y is an integer from 2 to 10 and J- | 11/28/1989 |
| 4861521 | Polymerizable liposome-forming lipid, and method for production thereof A polymerizable liposome-forming lipid represented by the following general formula I: ##STR1## wherein R stands for --CH2)2 N.sym. (CH3)3, --CH2)2 N.sym. H3... | 08/29/1989 |
| 4849137 | Process for producing lysophospholipids containing substantially no lysophospholipids except LPC Lysophospholipids containing substantially no lysophospholipids except LPC can be obtained by dissolving lysophospholipids in a polar solvent or a mixture of a polar solvent and a non-polar solvent, contacting the resulting solution with an ion exchanger,... | 07/18/1989 |
| 4837340 | Phospholipid-like compounds Compounds related to phospholipids and a method for their preparation are sclosed.... | 06/06/1989 |
| 4827011 | Antihypertensive phosphate derivatives Antihypertensive phosphate derivatives having the following formula are described: ##STR1## wherein X is a C1 -C24 branched or straight chain alkyl group; R is selected from the group consisting of hydrogen and C1 -C | 05/02/1989 |
| 4824978 | Complexes of glycerylphosphorylcholine The diacylesters, particularly bis(pyridyl-3-carboxilate) of glycerylphosphorylcholine, both optically active L(alpha) or racemic D,L(alpha) and their complexes having general formula: ##STR1## wherein: Y represents ##STR2## M represents Ca... | 04/25/1989 |
| 4814112 | Single-stage process for preparing mixed-substituted 1,2-diacyl-sn-clycero-3-phosphocholines Single-stage process for preparing mixed-substituted enantiomerically pure 1,2-diacyl-sn-glycero-3-phosphocholines of general formula I ##STR1## in which R1 and R2 are different and independently of each other denote a substitut... | 03/21/1989 |
| 4808480 | Polymerizable heterocyclic disulfide-based compounds and membranes made therefrom Compounds adapted to making polymerizable, cross linkable vesicles and methods for making these compounds comprising combining a phophatidylcholine derivative with an acid anhydride of a heterocyclic carbon/disulfide to form reaction products which when d... | 02/28/1989 |
| 4788182 | Phosphatidyl compounds, processes for their manufacture, and their use Described are phosphatidyl compounds of the formula I ##STR1## in which R1 represents C3-14 -alkanoyl, benzoyl, the acyl radical of an -aminocarboxylic acid that is other than glycine, L-alanine and derivatives thereof ha... | 11/29/1988 |
| 4783402 | Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique A process for producing a primary or secondary alcohol derivative of a phosopholipid which comprises reacting the phospholipid with a primary or secondary alcohol in the presence of phospholipase DM.... | 11/08/1988 |
| 4782019 | Enzymatic production of sphingophospholipid derivatives A process for producing a sphingophospholipid derivative comprising reacting a sphingophospholipid with a specified compound having an alcoholic hydroxyl group selected from the group consisting of specified primary alcohol compounds, specified secondary ... | 11/01/1988 |
| 4778912 | Phospholipid derivatives Phospholipid derivatives of the formula: ##STR1## wherein R1 is a higher alkyl, acylmethyl or alkylcarbamoyl group which may be substituted by cycloalkyl; R2 is a lower alkyl which may be substituted by carboxy, formyl or lower ... | 10/18/1988 |
| 4775758 | Phospholipids Novel phospholipids, inclusive of salts thereof, of the formula ##STR1## wherein R1 and R2 are independently an aliphatic hydrocarbon residue containing 1 to 20 carbon atoms, with the numbers of the carbon atoms for both totalli... | 10/04/1988 |
| 4764508 | Complexes of flavanolignans with phospholipids, preparation thereof and associated pharmaceutical compositions The invention relates to novel compounds comprising lipophilic complexes of silybin, silidianin, and silicristin with phospholipids, and the preparation of these complexes by non-conventional methods. Absorption of the novel compounds in the gastrointesti... | 08/16/1988 |
| 4762942 | Antihypertensive phosphate derivatives Antihypertensive phosphate derivatives having the following formula are described: ##STR1## wherein X is selected from one or more of: (a) C1 -C24 branched or straight chain alkyl; (b) C1 -C24 branched or s... | 08/09/1988 |
| 4761404 | Phospholipid analogs useful as PAF synthesis inhibitors There are disclosed phospholipid analogs which are useful as PAF synthesis inhibitors. These compounds inhibit PAF (platelet-activating factor) biosynthesis and are thereby useful in the treatment of various diseases or disorders mediated by the PAF such ... | 08/02/1988 |
| 4757053 | Pyridinecarboxamide or trimethoxybenzamide compounds derived from nitrogenous lipids, pharmaceutical compositions containing same which possess anti-convalsive and anti-epileptic properties Organic amide compounds of the formula ##STR1## wherein R1 --CO is a residue of a carboxylic acid with the proviso that the carboxylic acid is not a natural fatty acid normally bound to nitrogen of nitrogenous lipids, R2 is a hy... | 07/12/1988 |
| 4749805 | Phospholipid-like compounds Compounds related to phospholipids and a method for their preparations.... | 06/07/1988 |
| 4749696 | Hydroxy-[1-substituted carbonyl-2-(or 3-) piperidinyl methoxy]phosphinyloxy]-N,N,N-trialkylalkaneaminium hydroxide inner salt oxides having antitumor activity The invention discloses hydroxy-[1-substituted carbonyl-2-(or 3-) piperidinyl methoxy]phosphinyloxy]-N,N,N-trilkylalkaneaminium hydroxide inner salt oxides useful as antitumor agents, pharmaceutical compositions containing said compounds as an active ingr... | 06/07/1988 |
| 4739095 | Derivatives of N,N-(2-chloro-ethyl)-phosphoric acid amide The invention concerns derivatives of N,N-bis(2-chloroethyl)-phosphoric acid amide of general formula I ##STR1## wherein X and Y are the same or different and signify oxygen or NR3, R1 and R2 are the same or different... | 04/19/1988 |
| 4717512 | Preparation of acylated glycerophosphocholines and glycerophosphoethanolamines Preparation of chemically defined pure enantiomeric 1,2-diacyl-sn-glycero-3-phosphocholines and 1,2-diacyl-sn-glycero-3-phosphoethanolamines which are substituted in positions 1 and 2 of the glycerol, by acylation of triphenylmethyl derivatives of sn... | 01/05/1988 |
| 4710579 | 2-(acetoacetyloxy)-3-(octadecyloxy)propyl-3-trimethylammoniopropyl phosphate or a pharmaceutically acceptable salt thereof A compound provided by the present invention, of the formula ##STR1## wherein R1 is C14-20 alkyl; R2, R3 and R4 are independently hydrogen or C1-5 alkyl, or ##STR2## represents a ... | 12/01/1987 |
| 4702864 | Analogs of platelet activating factor 1-Thioether-1-acylaminophosphatidylcholine compounds are structural analogs of platelet activating factor and useful for inhibition of phospholipase A2, reduction of blood pressure, and alleviation of inflammation.... | 10/27/1987 |
| 4703130 | Antihypertensive phosphate derivatives Antihypertensive phosphate derivatives having the following formula are described: ##STR1## wherein W is selected from the group consisting of methyl and phenyl optionally substituted with C1 -C3 alkyl, C1 -C3 | 10/27/1987 |
| 4699901 | Diacyl derivatives of glycerylphosphorylcholine, their preparation, and antihyperlipidemic compositions The diacylesters, particularly bis(pyridyl-3-carboxilate) of glycerylphosphorylcholine, both optically active L(alpha) or racemic D, L(alpha) and their complexes having general formula: ##STR1## wherein: Y represents ##STR2## M represents C... | 10/13/1987 |
