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| Number | Title | Issue Date |
| 4937374 | Process for preparing methyl 3-methoxy-2-(2-phenoxyphenyl)propenoalis Process for the preparation of a compound of general formula (I): ##STR1## by reacting a compound of general formula (II) ##STR2## (X is halide; rings M and N are optionally substituted) with an optionally substituted phenol in the presence of a... | 06/26/1990 |
| 4914127 | 3-Demethylmevalonic acid derivatives, a process for their preparation pharmaceutical products based on these compounds, their use and intermediates 3-Demethylmevalonic acid derivatives of the formula I (δ-lactone) and Ia (corresponding dihydroxycarboxylic acid derivative) ##STR1## in which A-B, Z, R1, R2, R3 and R4 have the indicated meanings, a proce... | 04/03/1990 |
| 4894480 | Phenyl substituted-2,4,6,8-nonatetraenoic acid The compounds 9-phenyl-3,7-dimethyl-2,4,6,8 nonatetraenoic acids wherein the phenyl group is substituted with an alkyl, aminoalkyl, hydroxyalkyl, alkoxy, hydroxyalkylamino, and a hydroxy alkoxy group, and derivatives thereof which are used as disease modi... | 01/16/1990 |
| 4883614 | Phenyl substituted-2,4,6,8-nonatetraenoic acid The compounds 9-phenyl-3,7-dimethyl-2,4,6,8 nonatetraenoic acids wherein the phenyl group is substituted with an alkyl, aminoalkyl, hydroxyalkyl, alkoxy, hydroxyalkylamino, and a hydroxy alkoxy group, and derivatives thereof which are used as disease modi... | 11/28/1989 |
| 4883613 | Phenyl substituted-2,4,6,8-nonatetraenoic acid The compounds 9-phenyl-3,7-dimethyl-2,4,6,8 nonatetraenoic acids wherein the phenyl group is substituted with an alkyl, aminoalkyl, hydroxyalkyl, alkoxy, hydroxyalkylamino, and a hydroxy alkoxy group, and derivatives thereof which are used as disease modi... | 11/28/1989 |
| 4855211 | Polymeric phosphonium mordant and photographic element containing the same Phosphonium mordanting polymer, that is capable of fixing acid dyes and that comprises randomly distributed recurring units corresponding to the general formula (I) ##STR1## wherein: A represents a unit that is derived from a copolymerizable mon... | 08/08/1989 |
| 4788348 | Insecticidal alkenes Compounds of formula R3 --CH.dbd.CH--CR1 R2 --CH2 OCH2 R4 wherein R1 and R2 are H, alkyl or together form a cycloalkyl group with the adjacent carbon, R3 is a su... | 11/29/1988 |
| 4780251 | Phenyl substituted-2,4,6,8-nonatetraenoic acid The compounds 9-phenyl-3,7-dimethyl-2,4,6,8-nonatetraenoic acids wherein the phenyl group is substituted with an alkyl, aminoalkyl, hydroxyalkyl, alkoxy, hydroxyalkylamino, and a hydroxy alkoxy group, and derivatives thereof which are used as disease modi... | 10/25/1988 |
| 4769495 | Perfluoro-keto-ylids as precursors of polychloroketones, 1,2-diketones and quinoxalines The invention relates to a novel fluorinated pre-polymer and novel process steps in producing the same. The pre-polymers are quinoxaline materials derived by reaction of diketone linkage containing perfluoro-compounds with an aromatic diamine. The diketon... | 09/06/1988 |
| 4705900 | Insecticidal alkenes Compounds of formula R3 --CH.dbd.CH--CR1 R2 --CH2 OCH2 R4 wherein R1 and R2 are H, alkyl or together form a cycloalkyl group with the adjacent carbon, R3 is a su... | 11/10/1987 |
| 4683087 | Anti-cancer agents and processes for their preparation Compounds of the formula ##STR1## wherein R1 and R2 are either two hydrogen atoms or together form a methylene group, and each X is a bromo, iodo or tosyloxy group and the dotted bonds indicate that the central linkage is attach... | 07/28/1987 |
| 4648996 | Phenyl substituted-2,4,6,8-nonatetraenoic acid The compounds 9-phenyl-3,7-dimethyl-2,4,6,8 nonatetraenoic acids wherein the phenyl group is substituted with an alkyl, aminoalkyl, hydroxyalkyl, alkoxy, hydroxyalkylamino, and a hydroxy alkoxy group, and derivatives thereof which are used as disease modi... | 03/10/1987 |
| 4638002 | 2,3,4-trinor-1,5-inter-meta-phenylene-prostacyclin compounds useful in inhibiting thrombocyte aggregation The invention relates to new 2,3,4-trinor-1,5-inter-m-phenylene-PGI2 derivatives of the formula (I) ##STR1## wherein A stands for carboxy, cyano, tetrazolyl or --COOR3 or --CONR1 R2 ; R3 is C | 01/20/1987 |
| 4633020 | Perfluoro-keto-ylids as precursors of polychloroketones, 1,2-diketones and quinoxalines The invention relates to a novel fluorinated pre-polymer and novel process steps in producing the same. The pre-polymers are quinoxaline materials derived by reaction of diketone linkage containing perfluoro-compounds with an aromatic diamine. The diketon... | 12/30/1986 |
| 4583826 | Phenylethanes Compounds of the formula ##STR1## wherein R1 signifies trans-4-alkylcyclohexyl, 4'-alkyl-4-biphenylyl, p-(trans-4-alkylcyclohexyl)phenyl, 2-(trans-4-alkylcyclohexyl)ethyl or p-[2-(trans-4-alkylcyclohexyl)ethyl]phenyl and R2 sign... | 04/22/1986 |
| 4546184 | Perfluoro-keto-ylids as precursors of polychloroketones, 1,2-diketones and quinoxalines The invention relates to a novel fluorinated pre-polymer and novel process steps in producing the same. The pre-polymers are quinoxaline materials derived by reaction of diketone linkage containing perfluoro-compounds with an aromatic diamine. The diketon... | 10/08/1985 |
| 4540823 | Tetrahydrocarbyl phosphonium salts Novel advanced epoxy resins are prepared using phosphine or phosphonium salt initiators bearing at least one hydroxyphenyl or thiophenyl groups. These phosphonium salt initiators are novel compositions of matter. The resulting resins contain reduced quant... | 09/10/1985 |
| 4528114 | Acetylenes Compounds of the formula ##STR1## wherein ring B stands for 1,4-phenylene or a trans-1,4-disubstituted cyclohexane ring and A stands for a group with 1 to 3 six-membered rings, which together with ring B represents a central group of formulae II-XIII... | 07/09/1985 |
| 4493843 | Indole and indoline carboxylic acid compounds and method of use Indole and indoline derivatives of the formula: ##STR1## wherein indicates a double bond or a single bond between carbon atoms, R1 represents hydrogen, alkyl of 1 through 6 carbon atoms, or alkyl of 1 through 6 carbon atoms substituted b... | 01/15/1985 |
| 4482751 | Method for preparation of 8-methoxy-4,8-dimethyl-1-(4-isopropylphenyl)-nonane Disclosed is a method for the preparation of 8-methoxy-4,8-dimethyl-1-(4-isopropylphenyl)-nonane which comprises the steps of (a) reacting para-isopropylbenzyl chloride with triphenylphosphine in the presence of a suitable solvent for a sufficient period ... | 11/13/1984 |
| 4477645 | Immobilized epoxy advancement initiators Novel advanced epoxy resins are prepared using phosphine or phosphonium salt initiators bearing at least one hydroxyphenyl or thiophenyl groups. These phosphonium salt initiators are novel compositions of matter. The resulting resins contain reduced quant... | 10/16/1984 |
| 4476056 | Trifluoromethoxy analogs of aromatic retinoids Aromatic retinoids bearing a trifluoromethoxy substituent on the aromatic nucleus which are useful as antitumor agents and in the treatment of dermatological disorders as well as a method for their manufacture are disclosed.... | 10/09/1984 |
| 4417064 | Biphenyl compounds and method of preparing same The present invention relates to novel biphenyl compounds of the formula ##STR1## wherein one of R1 and R2 is hydrogen and the other is --CH3-m Xm wherein X is chloro or bromo and m is an integer one or two... | 11/22/1983 |
| 4407753 | 8-Oestra-1,3,5(10)-triene derivatives, processes for their preparation and pharmaceutical compositions The invention relates to new 8-oestra-1,3,5(10)-triene derivatives having the formula: ##STR1## in which R1 =H or a free, esterified or etherified hydroxy group; R2 =H or a free, esterified or etherified hydroxy group, with th... | 10/04/1983 |
| 4405626 | 9-Hydroxyoctahydrobenzo(c)quinolines analgesic compositions containing them and processes for producing analgesic with them 1,9-Dihydroxyoctahydrobenzo[c]quinolines (I), 1-hydroxyhexahydrobenzo[c]quinoline-9(8H)-ones (II), and 1-hydroxy-tetrahydrobenzo[c]quinolines (IV) useful as CNS agents, especially as analgesics and tranquilizers, as hypotensives, as agents for the tr... | 09/20/1983 |
| 4400385 | 9-Hydroxyoctahydrobenzo [c]quinolines, analgesic compositions containing them and processes for producing analgesia with them 1,9-Dihydroxyoctahydrobenzo[c]quinolines (I), 1-hydroxyhexahydrobenzo[c]quinoline-9 (8H)-ones (II), and 1-hydroxy-tetrahydrobenzo[c]quinolines (IV) useful as CNS agents, especially as analgesics and tranquilizers, as hypotensives, as agents for the t... | 08/23/1983 |
| 4380542 | 9-Hydroxyoctahydrobenzo[c]quinolines and their pharmaceutical compositions and method of use 1,9-Dihydroxyoctahydrobenzo[c]quinolines (I), 1-hydroxyhexahydrobenzo[c]quinoline-9(8H)-ones (II), and 1-hydroxy-tetrahydrobenzo[c]quinolines (IV) useful as CNS agents, especially as analgesics and tranquilizers, as hypotensives, as agents for the tr... | 04/19/1983 |
| 4372971 | Heterocyclic prostaglandin type compounds, medicaments containing them and processes for the preparation and use of these heterocyclic compounds and medicaments Disclosed are new heterocyclic compounds, medicaments containing them (for oral or parenteral administration) and processes for the preparation and use of these heterocyclic compounds and medicaments. The new compounds which particularly act as inhibitors... | 02/08/1983 |
| 4340737 | 9-Hydroxyoctahydrobenzo[C]quinolines and intermediates therefor 1,9-Dihydroxyoctahydrobenzo[c]quinolines (I), 1-hydroxyhexahydrobenzo-[c]quinoline-9(8H)-ones (II), and 1-hydroxy-tetrahydrobenzo[c]quinolines (IV) useful as CNS agents, especially as analgesics and tranquilizers, as hypotensives, as agents for the t... | 07/20/1982 |
| 4337337 | 2,5-Inter-o-phenylene-3,4-dinor-5,9-epoxy-6-iodo-PGF1 compounds The present invention provides 2,5-inter-o-phenylene-3,4-dinor-6,9-epoxy-6ଲ-6-iodo-PGF1 compounds. These compounds are intermediates for preparing 2,5-inter-o-phenylene-3,4-dinor-prostacyclin analogs, which are useful for phar... | 06/29/1982 |
| 4337203 | 2,5-Inter-o-phenylene-3,4-dinor-5,9-epoxy PGF1 amides The present invention provides 2,5-inter-o-phenylene-3,4-dinor-5,9-epoxy-PGF1 amides. These compounds are useful for a wide variety of pharmacological and therapeutical purposes, e.g., as antithrombotic agents.... | 06/29/1982 |
| 4337338 | 2,5-Inter-o-phenylene-3,4-dinor-5,9-epoxy-6-iodo-PGF1 amides The present invention provides 2,5-inter-o-phenylene-3,4-dinor-5,9-epoxy-6-iodo-PGF1 amides. These compounds are intermediates for preparing 2,5-inter-o-phenylene-3,4-dinor-prostacyclin analogs, which are useful for pharmacological ... | 06/29/1982 |
| 4328338 | 2,5-Inter-o-phenylene-3,4-dinor-6,9-epoxy-6ଲ-PGF1 amides The present invention provides 2,5-inter-o-phenylene-3,4-dinor-6,9-epoxy-6ଲ-PGF1 amides. These compounds are useful for a wide variety of pharmacological and therapeutical purposes, e.g., as antithrombotic agents.... | 05/04/1982 |
| 4326055 | Stilbene derivatives This invention is directed to 5,6,7,8-tetrahydro-naphthyl or indanyl stilbene derivatives which are useful as tumor inhibiting agents, in the treatment of neoplasms, dermatological conditions and rheumatic illnesses.... | 04/20/1982 |
| 4324889 | 2,5-Inter-o-phenylene-3,4 -dinor-6,9-epoxy-6ଲ-5-iodo-PGF1 amides The present invention provides 2,5-inter-o-phenylene-3,4-dinor-6,9-epoxy-6ଲ-5-iodo-PGF1 amides. These compounds are intermediates for preparing 2,5-inter-o-phenylene-3,4-dinor-prostacyclin analogs, which are useful for pharmac... | 04/13/1982 |
| 4321370 | 2,5-Inter-o-phenylene-3,4-dinor-6,9-epoxy-6ଲ-PGF1 compounds The present invention provides 2,5-inter-o-phenylene-3,4-dinor-6,9-epoxy-6ଲ-PGF1 compounds. These compounds are useful for a wide variety of pharmacological and therapeutical purposes, e.g., as antithrombotic agents.... | 03/23/1982 |
| 4316905 | Mercaptoacyl derivatives of various 4-substituted prolines This invention is directed to compounds of the formula ##STR1## and various intermediates therefore. The final products possess useful hypotensive activity.... | 02/23/1982 |
| 4316860 | Phosphonium compounds, a process for their preparation and a process for the preparation of asymmetrically substituted stilbene fluorescent brightening agents Phosphonium compounds of the formula in which R is preferably alkyl having 1 to 4 C atoms, cyclohexyl or phenyl, R1 is a substituted or unsubstituted aromatic radical, especially a phenyl radical, X is phenylene, 4,4'-biphenylene or 1,4- or 2,6... | 02/23/1982 |
| 4312810 | 2,5-Inter-o-phenylene-3,4-dinor-5,9-epoxy-9-deoxy-PGF1 compounds This invention relates to certain structural and pharmacological analogs of prostacyclin (PGI2) and 5,6-dehydroprostacyclin (PGI1) and 5,9-epoxy-9-deoxy-PGF1, wherein between the position beta to the carboxy (C-2) a... | 01/26/1982 |
| 4311705 | Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines Compounds, compositions and method of alleviating hypertension using a compound of the formula ##STR1## wherein R is hydrogen or lower alkyl; R1 is hydrogen, lower alkyl or phenyl-lower alkyl; R2 is hydrogen, lower alkyl or phenyl lo... | 01/19/1982 |
