Bizarre Patents
Behavior Modification Wristwatch
A wristwatch including a watch band and a watch body having an octagon shaped perimeter and being red in color and having the word STOP thereon to resemble a stop sign.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7129329 | Heme proteins hemAT-Hs and hemAT-Bs and their use in medicine and microsensors The present invention provides an isolated archael and bacterial heme binding protein which reversibly binds oxygen with a low affinity. The heme binding protein may be utilized as a blood substitute. The invention also provides a method for controlled storage of ox... | 10/31/2006 |
| 6846667 | Virulence genes and proteins, and their use The present invention is based on the identification of a series of virulence genes in E. coli K1, the products of which may be implicated in the pathogenicity of the organisms. The identification of the genes allows them, or their expressed products, to be u... | 01/25/2005 |
| 6733997 | Isolated nucleic acids encoding a secretory signal for expression and secretion of heterologous recombinant proteins A universal secretory signal originally derived from a piscine vitellogenin (Vtg) gene is inserted into various expression vectors for driving the secretion of the recombinant protein into the culture medium. This enhances the detection, quantification and downstrea... | 05/11/2004 |
| 6130204 | Peptides Oligopeptides which comprise amino acid sequences that are recognized and proteolytically cleaved by free prostate specific antigen (PSA) are described. Also described are assays which comprise such oligopeptides useful for determining free PSA protease a... | 10/10/2000 |
| 5543497 | Genes encoding and method of expressing a novel enzyme: phthalyl amidase Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides DNA compounds encoding the phthalyl amidase enzyme and methods for expressing such co... | 08/06/1996 |
| 4873190 | Heterodimeric T lymphocyte receptor Disclosed is a heterodimeric T lymphocyte receptor comprising an alpha and a beta subunit. Each subunit consists of a signal peptide, variable, joining, constant, transmembrane, and cytoplasmic regions. The two subunits are connected by a disulfide bond b... | 10/10/1989 |
| 4871670 | Molecular cloning and characterization of a gene sequence coding for human relaxin Genes and DNA transfer vectors for the expression of human preprorelaxin; sub-units thereof, including genes and transfer vectors for expression of human prorelaxin and the individual A, B and C peptide chains thereof; and equivalents of all such genes. M... | 10/03/1989 |
| 4868112 | Novel procoagulant proteins Novel procoagulant proteins are disclosed which comprise the amino acid sequence: wherein region A represents the polypeptide sequence Ala-20 through Arg-759 substantially as shown in Table 1; region B represents the polypeptide sequence Ser-1709 through ... | 09/19/1989 |
| 4865974 | Bacterial methionine N-terminal peptidase Methods for obtaining N-terminal methionine-free proteins involve a novel E. coli methionine amino peptidase. The method is capable of in vitro or in vivo application. For in vivo application, a plasmid-borne DNA encoding the peptide is expressed in a bac... | 09/12/1989 |
| 4865982 | Cloned streptomycete gene A DNA fragment from Streptomyces sp. which contains the XP55 gene expression unit.... | 09/12/1989 |
| 4859600 | Recombinant procaryotic cell containing correctly processed human growth hormone The production of mature hGH in E coli and Pseudomonas strains transformed by a plasmid which encodes pre hGH (comprising the signal polypeptide and the hormone itself) is described. These prokaryotes process the pre-hGH to cleave the signal sequence and,... | 08/22/1989 |
| 4857637 | Methods and compositions for immunologically modulating growth hormone receptor activity The activity of growth-associated receptors is modulated in vivo in a controlled and reproducible fashion by immunizing animals against target growth-associated receptors. This is accomplished by the use of immunogens predetermined to induce primarily ago... | 08/15/1989 |
| 4855238 | Recombinant gamma interferons having enhanced stability and methods therefor The present invention relates to novel, stable recombinant gamma interferons exhibiting in greater or less degree the antiviral and antiproliferative activity in humans and pH 2 labile properties characteristic of native human gamma interferon. The amino ... | 08/08/1989 |
| 4851341 | Immunoaffinity purification system A process is disclosed for purifying a recombinant fusion protein having an N-terminal identification sequence comprising multiple anionic amino acid residues, comprising forming a complex of the protein with a divalent cation dependent monoclonal antibod... | 07/25/1989 |
| 4849351 | Multiple reading frame Escherichia coli expression vectors Vector plasmids are constructed to provide sites for insertion of a structural gene in phase with three reading frames downstream from the promoter of alkaline phosphatase gene of Escherichia coli.... | 07/18/1989 |
| 4847325 | Conjugation of polymer to colony stimulating factor-1 A biologically active CSF-1 protein is selectively conjugated via certain amino acid residues or carbohydrate moieties to a water-soluble polymer selected from polyethylene glycol or polypropylene glycol homopolymers, polyoxyethylated polyols, or polyviny... | 07/11/1989 |
| 4839293 | DNA encoding streptavidin, streptavidin produced therefrom, fused polypeptides which include amino acid sequences present in streptavidin and uses thereof DNA which encodes the polypeptide streptavidin has been isolated as a fragment 2 kb in length derived from a restriction endonuclease digestion of the chromosomal DNA of Streptomyces avidinii. The nucleic acid sequence of the gene and the amino acid seque... | 06/13/1989 |
| 4839283 | Method of expressing alpha-1-antitrypsin in yeast A method is provided for expressing human alpha-1-antitrypsin in yeast utilizing a wild-type strain and a hyperproduction mutant, GK100.... | 06/13/1989 |
| 4826763 | Process for preparing glucagon or fragments or derivatives thereof in yeast Glucagon or fragments or derivatives thereof are prepared by cultivation of a yeat strain transformed with a replicable expression vehicle comprising a gene encoding the expression of such products. Synthetic genes encoding glucagon or derivatives thereof... | 05/02/1989 |
| 4816567 | Recombinant immunoglobin preparations Altered and native immunoglobulins, including constant-variable region chimeras, are prepared in recombinant cell culture. The immunoglobulins contain variable regions which are immunologically capable of binding predetermined antigens. Methods are provid... | 03/28/1989 |
| 4816396 | Method and vector organism for controlled accumulation of heterologous gene products in bacillus subtilis The invention discloses a method and cloning vectors useful for the production of cloned heterologous gene products in B. subtilis. Use of the method and vector allows the host to produce the heterologous gene product as a single unfused peptide having no... | 03/28/1989 |
| 4816565 | Interleukin 2 receptor and a method for production thereof Interleukin 2 receptor protein having the following properties: (a) molecular weight: 40 to 43 kd, (b) pI of 5.2 to 4.4, (c) amino acid sequence (N-terminal): ##STR1##... | 03/28/1989 |
| 4810645 | Microbial production of mature human leukocyte interferon K and L This invention relates to the microbial production, via recombinant DNA technology, of new human leukocyte interferons, Le IF-K and Le IF-L for use in the treatment of viral and neoplastic diseases, and to the means and end products of such production.... | 03/07/1989 |
| 4801537 | Vector for expression of polypeptides in bacilli A replicable plasmidic expression vector, capable of high levels of expression and secretion of polypeptides in a bacillus is disclosed. The vector contains a DNA sequence comprising the promoter and regulatory regions which control expression and secreti... | 01/31/1989 |
| 4789702 | Feline leukemia virus vaccine Polypeptides that are synthesized or expressed directly in microorganisms, include an amino acid sequence that is homologous to at least a portion of gp70 envelope protein of FELV, and are immunogens that elicit or prime a humoral response in cats and imm... | 12/06/1988 |
| 4783415 | Gene coding for signal peptides and utilization thereof A DNA segment of a gene coding for a signal peptide is disclosed the segment is to be used in a host-vector system employing a bacterium belonging to the genus Streptomyces as a host by incorporation in the vector DNA. The segment comprises a DNA having a... | 11/08/1988 |
| 4782139 | Selective chemical removal of a protein amino-terminal residue The invention relates to a process and compounds useful therein for producing a compound having an amino acid sequence defining a biologically active peptide or protein from a compound of the formula in which X is the residue of a naturally occurring amino aci... | 11/01/1988 |
| 4775622 | Expression, processing and secretion of heterologous protein by yeast Yeast organisms are caused to express, process, and secrete protein that is normally heterologous to yeast and not required for its viability by transforming yeast with an expression vector containing a gene encoding heterologous protein and a signal sequ... | 10/04/1988 |
| 4772557 | DNA clone of human skin fibroblast collagenase enzyme A cDNA having a base sequence for human skin fibroblast collagenase has been cloned and characterized and the amino acid sequence of the human skin fibroblast protein has been determined.... | 09/20/1988 |
| 4769327 | Secretion vector A vector including a DNA sequence encoding a secretory signal sequence substantially identical to the secretory signal encoding sequence of the Bacillus licheniformis -amylase gene; upstream from the signal-encoding sequence, a promoter sequence an... | 09/06/1988 |
| 4767709 | Growth-related hormones Proliferin, a growth-related hormone of the prolactin-growth hormone family is provided, as well as DNA molecules encoding proliferin and methods of expressing the DNA molecules in vivo. Methods of probing for proliferin encoding DNA are also provided.... | 08/30/1988 |
| 4764593 | Manufacture and expression of genes for urogastrone and polypeptide analogs thereof Disclosed are DNA sequences comprising structural genes coding for (1) a polypeptide having the amino acid sequence and properties of urogastrone and for (2) polypeptide analogs thereof which differ in terms of the identity and/or location of one or more ... | 08/16/1988 |
| 4762791 | Human immune interferon Disclosed is a complete discription of the preparation of novel, recombinant human immune interferon via recombinant DNA techniques utilizing any of an assortment of expression vectors and host cultures. The recombinant human immune (gamma) interferon (IF... | 08/09/1988 |
| 4761375 | Human interleukin-2 cDNA sequence The mRNA of a distinct human Interleukin-2 concentrated from a plasma source lead to the production and cloning of its cDNA and the elucidation of its sequence and that of the mature protein. Transfer vectors for production of such Interleukin-2 are discl... | 08/02/1988 |
| 4758656 | Novel human interferon-gamma polypeptide derivative Disclosed is a novel derivative of human interferon-γ polypeptide, a recombinant plasmid wherein a DNA fragment coding for said polypeptide is incorporated and a process for producing the derivative of human interferon-γ polypeptide using a microorganis... | 07/19/1988 |
| 4758655 | Synthetic polypeptide corresponding to a portion of the heat-labile enterotoxin of escherichia coli, compositions and methods of therewith Synthetic polypeptides containing about 10 to about 35 amino acid residues corresponding in sequence to the amino acid residue sequence of about position 35 to about position 95 from the amino-terminus of the B-subunit of the heat-labile enterotoxin of Es... | 07/19/1988 |
| 4755465 | Secretion of correctly processed human growth hormone in E. coli and Pseudomonas The production of mature hGH In E. coli and Pseudomonas strains transformed by a plasmid which encodes pre hGH (comprising the signal polypeptide and the hormone itself) is described. These prokaryotes process the pre-hGH to cleave the signal sequence and... | 07/05/1988 |
| 4753873 | Peptides for the diagnosis of HTLV-III antibodies, their preparation and use Certain peptide fragments of the human T-cell leukemia (lymphotropic) virus (HTLV-III) are particularly immunoreactive to HTLV-III antibodies, and can therefore be applied to immunodiagnostic tests for the detection of antibodies to HTLV-III.... | 06/28/1988 |
| 4745056 | Streptomyces secretion vector Cloning vectors are disclosed to obtain secretion of a desired protein from a host Streptomyces when a structural gene coding for the protein is inserted into the vector. The vector has: (1) regulatory DNA that includes a promoter sequence effective to st... | 05/17/1988 |
| 4743679 | Process for producing human epidermal growth factor and analogs thereof Disclosed is a process for producing a fusion protein comprising epidermal growth factor (EGF) attached through a Glu-residue to a leader. Treatment of the fusion protein with a Staphylococcus aureus V8 protease specific for cleaving peptides at a Glu-lin... | 05/10/1988 |
