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Pneumatic Shoe Lacing Apparatus
This invention provides a pneumatic shoe lacing apparatus for the pneumatic lacing of shoe.
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| Number | Title | Issue Date |
| 6025540 | Transgenic non-human mammals producing EC-SOD protein in their milk The present invention relates to a transgenic non-human mammal comprising a DNA sequence encoding human extracellular superoxide dismutase (human EC-SOD) or a variant thereof which is expressed in the milk. Transgenic mice containing a chimeric whey acidi... | 02/15/2000 |
| 6018096 | Animal model for engraftment, proliferation and differentiation of human hematopoietic stem cells A chimeric, non-human, genetically-immunocompetent mammal is disclosed. The hematopoietic system of the mammal has human passaged bone marrow stromal cells and human hematopoietic stem cells obtained from a CD34+ -enriched bone marrow fraction,... | 01/25/2000 |
| 5994617 | Engraftment of immune-deficient mice with human cells A process for transplanting into an immunodeficient mouse, which is deficient in T-cells and B-cells, human cells to form a chimeric mouse is provided. The transplanted human cells proliferate and thereby permit in vivo study of the human cells. The human... | 11/30/1999 |
| 5969211 | Pantropic retroviral vectors for gene transfer in mollusks A method for introducing foreign nucleic acid sequences into marine mollusks. A pantropic retroviral vector containing a foreign gene sequence is introduced into fertilized mollusk embryos by electroporation. The gene sequence becomes integrated into the ... | 10/19/1999 |
| 5965149 | Granular formulation of biological entities with improved storage stability A method for preparing granules containing pesticidal or herbicidal biological organisms which can be stored for prolonged periods and conveniently dispensed is provided. Compositions are provided which comprise granules containing entomopathogenic nemato... | 10/12/1999 |
| 5962321 | Leukemia inhibitory factor from mammalian species and use thereof to enhance implantation and development of embryos Leukemia inhibitory factor or LIF as an addition to culture media promotes the development of embryos to the implantation stage. Growth in the presence of LIF increases the percentage of embryos that reach the implantation stage than growth without LIF. L... | 10/05/1999 |
| 5962648 | Production of human recombinant collagen in the milk of transgenic mammals Production of human procollagen or collagen in cells which ordinarily do not produce these molecules is effected by constructing expression systems compatible with mammary glands of non-human mammals. For example, expression systems can be microinjected i... | 10/05/1999 |
| 5952488 | Androgen regulation with DNA sequences of rat probasin gene A DNA sequence (-426 to +28 base pairs) cloned from the probasin (PB) gene promoter region confers androgen regulation in cell culture and prostate specific expression in transgenic non-human eukaryotic animals. Various PB promoter fragments impart prefer... | 09/14/1999 |
| 5944652 | Method for breeding chickens Disease resistance in chickens has been associated with the Rfp-Y system of major histocompatability genes in chickens. A method for breeding chickens to produce disease resistant offspring involves selecting at least one parent that has an Rfp-Y haplotyp... | 08/31/1999 |
| 5939598 | Method of making transgenic mice lacking endogenous heavy chains The subject invention provides non-human mammalian hosts characterized by inactivated endogenous Ig loci. The hosts are produced by repetitive transformations of embryonic stem cells by homologous recombination, preferably in conjunction with breeding. Di... | 08/17/1999 |
| 5932250 | Anti-cholesterolemic egg, vaccine and method for production, and use The present invention is directed to the treatment of vascular disorders particularly arteriosclerosis and atherosclerosis in warm-blooded animals. The invention encompasses the ingestion, by warm-blooded animals, of eggs or egg fractions derived from fem... | 08/03/1999 |
| 5932237 | Steinernema Sp. nematode for suppression of Helicoverpa zea and Spodoptera frugiperda A novel entomopathogenic nematode of the genus Steinernema, which is effective as a biopesticide for the control of insects, and particularly the corn earworm, Helicoverpa zea, and the fall armyworm, Spodoptera frugiperda. This nematode has been identifie... | 08/03/1999 |
| 5925802 | Functional reconstitution of SCID-bo mice with bovine fetal hematopoietic tissues The present invention provides a non-human chimeric mammal, comprising a severe-combined immunodeficient mammal engrafted with bovine immune system tissues, wherein said chimeric mammal is functionally reconstituted. Also provided is a method of producing... | 07/20/1999 |
| 5917123 | Transgenic mice containing a nucleic acid encoding tumor necrosis factor- under the control of a cardiac specific regulatory region The present invention provides transgenic nonhuman mammals that exhibit elevated levels of tumor necrosis factor alpha in myocardium relative to nontransgenic control mammals, and methods for making transgenic non-human mammals. The invention further prov... | 06/29/1999 |
| 5885836 | FLP-mediated gene modification in mammalian cells, and compositions and cells useful therefor A gene activation/inactivation and site-specific integration system has been developed for mammalian cells. The invention system is based on the recombination of transfected sequences by FLP, a recombinase derived from Saccharomyces. In several cell lines... | 03/23/1999 |
| 5880326 | Models for measuring the sense of smell The invention provides methods and compositions for measuring the sense of smell, including animals having general anosmia as a result of a genetic mutation. The genetic mutation disrupts a function of a protein required for cyclic nucleotide mediated sig... | 03/09/1999 |
| 5866757 | Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems Non-human chimeric mammals are created from a mammal having hematopoietic cells replaced with hematopoietic cells from a hematopoietic deficient mammal donor, and optionally in which xenogeneic cells and/or tissue are engrafted. The xenogeneic, preferably... | 02/02/1999 |
| 5858354 | Repopulation of testicular Seminiferous tubules with foreign cells, corresponding resultant germ cells, and corresponding resultant animals and progeny An animal harboring a non-native germ cell, its corresponding line, and the corresponding germ cells, are obtained by colonizing the testis (or testes) of a host animal with primitive cells followed by raising and/or breeding the host.... | 01/12/1999 |
| 5849288 | Method for production of monoclonal antibodies in chimeric mice or rats having xenogeneic antibody-producing cells Non-human chimeric mammals are created from a mammal having hematopoietic cells replaced with hematopoietic cells from a hematopoietic deficient mammal donor, and in which xenogeneic hematopoietic cells and/or tissue are engrafted. The chimeric mammal can... | 12/15/1998 |
| 5849991 | Mice homozygous for an inactivated 1,3-galactosyl transferase gene Human pre-formed xenoantibodies play an important role in the hyperacute rejection response in human xenotransplantation. Disclosed are materials and methods for removing or neutralizing such antibodies. Also disclosed are materials and methods for reduci... | 12/15/1998 |
| 5849349 | Anti-cholesterolemic egg, vaccine and method for production, and use Eggs that affect lipid and cholesterol levels obtained from avian species that are hyperimmunized against a variety of bacterial antigens are disclosed. These eggs are useful as a dietary supplement for humans and other animals.... | 12/15/1998 |
| 5824841 | Tetraploid shellfish Provided by this invention are novel tetraploid mollusks, including oysters, scallops, clams, mussels and abalone. Also, provided are a method for producing the tetraploid mollusks and a method for producing triploid mollusks by mating the novel tetraploi... | 10/20/1998 |
| 5770786 | Method for the isolation and/or testing of genes and promoters involved in plant-nematode interactions using plants of the genus arabidopsis The invention provides a method for infecting a root of a plant of the genus Arabidopsis with a plant parasitic nematode under monoxenic conditions, comprising the steps of: (a) contacting the root with a plant parasitic nematode in the presence of a gell... | 06/23/1998 |
| 5602301 | Non-human mammal having a graft and methods of delivering protein to myocardial tissue Described are preferred myocardial grafts of skeletal myoblasts or cardiomyocytes, and cellular compositions and methods useful in obtaining the grafts. The myocardial grafts are stable and can be used, for example, to deliver recombinant proteins directl... | 02/11/1997 |
| 5602302 | Models for asthma guinea pig The present invention relates to a method of preparing bronchial hypersensitive or hyposensitive guinea pigs by selective breeding on the basis of bronchial sensitivity to inhalant chemicals inducing bronchoconstriction. The hypersensitive guinea pigs of ... | 02/11/1997 |
| 5557033 | Method of increasing egg production in avian species by active immunization against vasoactive intestinal peptide The present method of increasing egg production in laying turkey hens includes actively immunizing the hens with vasoactive intestinal peptide. The peptide is conjugated to a protein to induce an antibody response in the hens. The resulting antibodies tie... | 09/17/1996 |
| 5549884 | Rat or mouse exhibiting behaviors associated with human schizophrenia This invention provides a unique and surprisingly accurate animal model for human schizophrenia. The animals are brain damaged while prepubescent. The brain damage consists of a ventral hippocampus lesion induced by exposure of the hippocampus region to a... | 08/27/1996 |
| 5183950 | Commercial storage and shipment of entomogenous nematodes Methods and materials for inducing anhydrobiosis in entomogenous nematode infective juveniles and then maintaining and storing them in an apparently anhydrobiotic state are described. Infective juveniles are induced into an anhydrobiotic state at relative... | 02/02/1993 |
