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...that after Walter Hunt patented the safety pin in 1849, he sold the rights to it for $400?
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| Number | Title | Issue Date |
| 7574931 | Quantitative sampling device A quantitative sampling device comprises a sampling part and a case; the sampling part further has a sampling loop with a predetermined size for sampling a fixed amount of an liquid sample; and the case includes a buffer solution with a predetermined volume, the sam... | 08/18/2009 |
| 7371247 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the pe... | 05/13/2008 |
| 7335188 | Lumbar puncture fluid collection device A device for collecting spinal fluid during a lumbar puncture or other medical procedure includes: a) an upper, generally cup-shaped portion including an open top, an upper cup side wall, an upper cup base plate at a lower end of the upper cup side wall, and a drain... | 02/26/2008 |
| 7331931 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generato... | 02/19/2008 |
| 7316700 | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties A lancing device, an embodiment of which controls the advancement and retraction of a lancet by monitoring the position of the lancet in conjunction with a lancet controller which incorporates a feedback loop for modulating the lancet driver to follow a predetermine... | 01/08/2008 |
| 7291117 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a voice coil based penetrating member driver. A plurality of penetrating members are included. A transport mechanism is configured to... | 11/06/2007 |
| 7282181 | Fluid collection and testing device A fluid collection and testing device includes a collection vial having a bottom and an open top along with an expresser sized for insertion into the vial open end. The expresser includes a ribbed base enabling fluid to pass therethrough and a support member holds t... | 10/16/2007 |
| 7258693 | Device and method for variable speed lancet A method of penetrating tissue is provided. The method comprises using a lancet driver to advance a lancet into the tissue; advancing the lancet at a first desired velocity in a first layer of tissue; advancing the lancet at a second desired velocity in a second lay... | 08/21/2007 |
| 7257991 | Sample testing device A sample testing device has a buffer container that can hold buffer fluid, a filter with a securement for holding a test strip, the test strip, a test strip container having a receptacle to accommodate the filter, so that when the filter is held therein the test str... | 08/21/2007 |
| 7244265 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a drive force generator and a penetrating member operatively coupled to the force generator. The force generator moves the member alo... | 07/17/2007 |
| 7244394 | Methods and kits for assays of analytes of interest in tears The invention, in one aspect, provides a strip for tear collection. The strip has a first end and an opposite second end and preferably has substantially uniform cross-sections from the first end to the second end. The strip is made of a hydrogel material in substan... | 07/17/2007 |
| 7232451 | Method and apparatus for penetrating tissue A skin penetrating system has a housing member and a plurality of penetrating members positioned in the housing member. A tissue stabilizing device is coupled to the housing member. A user interface is configured to relay at least one of, skin penetrating performanc... | 06/19/2007 |
| 7229458 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of cartridges each with a distal port and a proximal port. A plurality of penetrating members are provided, each coupled to a cartridge and having a sharpened distal tip and a shaft portion slidably disposed within th... | 06/12/2007 |
| 7226461 | Method and apparatus for a multi-use body fluid sampling device with sterility barrier release A device for use with a gripper is provided. A cartridge is provided that defines a plurality of cavities. A plurality of penetrating members are at least partially contained in the cavities of the cartridge. The penetrating members are slidably movable to extend ou... | 06/05/2007 |
| 7224448 | Apparatus and methods for evaluating an optical property of a liquid sample An apparatus for acquiring and holding minimum size liquid samples with predetermined pathlength and methods using the same. ... | 05/29/2007 |
| 7198606 | Method and apparatus for a multi-use body fluid sampling device with analyte sensing A device for use with a penetrating member driver to penetrate tissue is provided. A plurality of penetrating members are coupled to a single cartridge and are operatively couplable to the penetrating member driver. The penetrating members are movable to extend radi... | 04/03/2007 |
| 7175812 | Automatic sampler and needle for the same The surface of a needle for collecting samples is coated with a coating material lower in chemical activity than a base metal of the needle. More specifically, the surface of the needle may be coated with a layer of gold or platinum. Alternatively, the surface of th... | 02/13/2007 |
| 7160689 | Pretreatment instrument of saliva and pretreatment method of saliva In a pretreatment instrument and a pretreatment method of saliva, used for identification and quantitation of Streptococcus mutans in saliva by the immunochromatographic method utilizing an antigen-antibody reaction, the instrument includes a swab and a mixin... | 01/09/2007 |
| 7153699 | Microfabricated two-pin system for biomolecule crystallization A two-pin liquid handling system for crystallizing biomolecules comprises a pair of interacting pins for holding a droplet of liquid therebetween. Each pin includes a tip spaced predetermined distance from the other pin to define a sample acquisition region. The two... | 12/26/2006 |
| 7131342 | Method of preventing short sampling of a capillary or wicking fill device The current invention provides a device, and a method for using the device, for ensuring that a capillary or wicking fill device is fully filled. In particular this invention is directed to, but not limited to, use with capillary or wicking action filled electrochem... | 11/07/2006 |
| 7114403 | Fluid collection and application device and methods of use of same The present invention is a device for conveniently collecting and storing liquid samples, as well as applying an aliquot of the sample to a test device, such as a lateral flow immunoassay. The present invention comprises an absorbent swab and a dropper container con... | 10/03/2006 |
| 7094464 | Multi-layer coated porous materials and methods of making the same Multi-layer coated materials and methods of making them are disclosed. In a specific embodiment, a porous polymeric substrate is pre-activated and immersed in a polyelectrolyte solution to form a first layer having an electric charge and at least one functional grou... | 08/22/2006 |
| 7078480 | Process for stabilizing the content of glycated protein of a sample on a matrix material The invention concerns a method for stabilizing the content of glycated protein in a sample on a matrix material, which is characterized in that the matrix material is impregnated with boric acid buffer with a pH which is larger or equal to 10.5 or a transition meta... | 07/18/2006 |
| 7071000 | Method for sampling reaction products A method for sampling reaction products includes delivering a reactant through a sampling probe to contact a substance deposited on a substrate and reacting the reactant to form a reaction product. At least a portion of the reaction product is withdrawn through the ... | 07/04/2006 |
| 7043821 | Method of preventing short sampling of a capillary or wicking fill device The current invention provides a device, and a method for using the device, for ensuring that a capillary or wicking fill device is fully filled. In particular this invention is directed to, but not limited to, use with capillary or wicking action filled electrochem... | 05/16/2006 |
| 7041068 | Sampling module device and method A tissue penetration device and method of using same that may include a lancet module or sampling module. The sampling module may optionally be in a cartridge configuration and include sampling and analyzing functions, which may be integrated. ... | 05/09/2006 |
| 7025774 | Tissue penetration device A tissue penetration device and method of using same. The tissue penetration device may optionally include sampling and analyzing functions, which may be integrated. An embodiment provides control of a lancet used for sampling blood. Electric field coils or solenoid... | 04/11/2006 |
| 6864091 | Sampling probe A sampling probe for delivering a reactant to a substance deposited on a substrate to form a reaction product and for transporting the reaction product to a product analyzer for analysis. The probe includes a tip positionable over the substance on the substrate. The... | 03/08/2005 |
| 6835352 | Spotting pin A spotting pin 10 capable of spotting equal amounts of a solution in a sequential manner comprises a first member 11 having a solution holding portion 13 formed at the tip thereof for holding a predetermined amount of solution, and a second memb... | 12/28/2004 |
| 6823750 | Method of preventing short sampling of a capillary or wicking fill device The current invention provides a device, and a method for using the device, for ensuring that a capillary or wicking fill device is fully filled. In particular this invention is directed to, but not limited to, use with capillary or wicking action filled electrochem... | 11/30/2004 |
| 6820507 | Apparatus for extracting a representative sample of water, oil and sediment from a container A method and apparatus for extracting a representative sample of water, oil and sediment from a container. The apparatus is a container closure having a tube extending therethrough, such that fluids can be extracted from any closed container through the tube when cl... | 11/23/2004 |
| 6689323 | Method and apparatus for liquid transfer Liquids are transferred from a plurality of wells or depots having openings arranged in a selected format to one or more receptacles, by displacing liquid contained in each well so that a convex meniscus swells from the opening, and contacting the recepta... | 02/10/2004 |
| 6629626 | Liquid transfer device A device for transferring small drops of liquid from one or more liquid holders to one or more liquid destinations is disclosed. The device includes a support member and a plurality of fluid transfer members extending from the support member. Each fluid t... | 10/07/2003 |
| 6584832 | High-temperature characterization of polymer libraries Rapid characterization and screening of polymer samples to determine average molecular weight, molecular weight distribution and other properties is disclosed. Rapid flow characterization systems and methods, including liquid chromatography and flow-injec... | 07/01/2003 |
| 6578409 | Method and device for determining the threshold of heavy fraction deposit contained in a liquid hydrocarbon fluid The invention concerns a method whereby a fluid sample is brought (1) at constant pressure Pe and temperature maintaining the heavy fractions, in particular asphaltenes, in dissolved state and/or in stable colloidal state, at the intake (4) of a capillary... | 06/17/2003 |
| 6571651 | Method of preventing short sampling of a capillary or wicking fill device The current invention provides a device, and a method for using the device, for ensuring that a capillary or wicking fill device is fully filled. In particular this invention is directed to, but not limited to, use with capillary or wicking action filled ... | 06/03/2003 |
| 6557427 | Capillaries for fluid movement within microfluidic channels A capillary for introduction of whole blood into an analysis device. The capillary has a variable volume along its length, which allows the liquid sample to be drawn into the interior of the cartridge, away from the inlet, reducing the risk of contaminati... | 05/06/2003 |
| 6475440 | Applicator for use in deposition of fluid samples onto a substrate surface Applicator devices for depositing a fluid sample onto a substrate, as well as methods for their use, are provided. The subject devices are elongate in shape and have a first end and a second end. The first end has a planar surface of substantially circula... | 11/05/2002 |
| 6245559 | Handle for inoculating loop A two-piece handle assembly (10, 10a) including a plunger (12, 12a) and a body (24, 24a) having an axial bore (50, 50a) in which plunger (12, 12a) can move between retracted and extended positions. The upper end (28) of body (24, 24a) includes a pair of o... | 06/12/2001 |
| 6245558 | Transfer loop A transfer loop has a loop, a stem, and an optional main body member. The loop is connected to the stem and encloses a slit resulting in a discontinuous loop. The slit is positioned either to one side of the loop or at the bottom of the loop and aligned r... | 06/12/2001 |
