"To place a man in a multi-stage rocket and project him into the controlling gravitational field of the moon where the passengers can make scientific observations, perhaps land alive, and then return to earth--all that constitutes a wild dream worthy of Jules Verne. I am bold enough to say that such a man-made voyage will never occur regardless of all future advances."
Lee deForest, American radio pioneer ; 1957
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| Number | Title | Issue Date |
| 7384430 | Low crystalline polymeric material for orthopaedic implants and an associated method A component made from a crosslinked polymeric material, wherein the crosslinked polymeric material has a reduced crystallinity is described. An associated method for fabricating such a component is also described. ... | 06/10/2008 |
| 7311970 | Medical device having surface modification with superoxide dismutase mimic A medical device comprising a substrate having a plasma polymerized functionality bonded to at least a portion of the substrate. A superoxide dismutase mimic agent having a complimentary functional group to the plasma polymerized functionality is bonded to the porti... | 12/25/2007 |
| 7214245 | Associating hydrogels for nucleus pulposus replacement in intervertebral discs A prosthetic nucleus prepared from blends of polyvinylalcohol and polyvinyl pyrollidone or its copolymers for replacement of the nucleus pulposus in intervertebral discs is provided. Also provided are methods of replacing the nucleus pulposus and treating disc degen... | 05/08/2007 |
| 7094418 | Crosslinkable macromers A crosslinkable macromer system and related methods of preparing the system and using the system in the form of a crosslinked matrix between a tissue site and an implant article such as a tissue implant or on the porous surface of a prosthetic device. The macromer s... | 08/22/2006 |
| 7060347 | Bending element with behavior dependent on the direction of rotation An anisotropic bending element which contains at least the following layers: I. a reinforcing layer I, which contains a fibrous reinforcing component I with a tensile modulus of elasticity of from 1,800 to 20,000 N/mm2, ... | 06/13/2006 |
| 7041713 | Artificial dura mater The present invention provides an artificial dura mater which comprises an amorphous or low crystallinity polymer as a constituent component and which prevents the cerebrospinal fluid leakage. ... | 05/09/2006 |
| 6942695 | Biomedical devices with polyimide coating Intraocular lenses and methods producing the same are provided. The intraocular lens includes an optic and a haptic that are integrally formed together. The haptic has a polyimide coating. The polyimide coating promotes fibrosis in the surrounding eye tissue to enha... | 09/13/2005 |
| 6918936 | Thermoplastic liner blank A soft and elastic prosthetic liner blank for customizing to an individual user is formed from thermoplastic material and molded to a hollow, generally rotation symmetric shape having at least one radial dimension. The liner blank has an open proximal end for insert... | 07/19/2005 |
| 6855366 | Nitric oxide-modified linear poly(ethylenimine) fibers and uses therefor A novel coating for medical devices provides nitric oxide delivery using nanofibers of linear poly(ethylenimine)diazeniumdiolate. Linear poly(ethylenimine)diazeniumdiolate releases nitric oxide (NO) in a controlled manner to tissues and organs to aid the healing pro... | 02/15/2005 |
| 6818018 | In situ polymerizable hydrogels Compositions and methods for forming hydrogels in situ through a combination of physical and chemical crosslinking processes are provided in which physical crosslinking is mediated by one or more natural or synthetic components that stabilize the a hydrogel-forming ... | 11/16/2004 |
| 6712850 | Porous tissue scaffolds for the repair and regeneration of dermal tissue The present invention is a synthetic, biocompatible, bioabsorbable, porous foam tissue scaffolds possessing physicochemical properties suitable for use in the repair and regeneration of dermal tissue and to methods of preparing the foam scaffold. ... | 03/30/2004 |
| 6663668 | Hydratable siloxane comprising porous polymers An hydratable porous polymer comprising a polymerized polyorganosiloxane macromonomer of formula I wherein c is in the range of from 0 to 5, preferably in the range of from 0 to 3; M may be the same or different and is a difunctional block of molecular ... | 12/16/2003 |
| 6656217 | Medical device coated with a polymer containing a nitric oxide releasing organometallic nitrosyl compound useful for the prevention of platelet aggregation The aggregation of platelets on the surface of a foreign body exposed to the flowing blood of a living being (such as plastic tubing, a balloon or the end of a catheter surgically inserted in a blood vessel, a stent implanted therein or synthetic grafts, ... | 12/02/2003 |
| 6596024 | Polymeric heart valve fabricated from polyurethane/polysiliconeurethane blends Biocompatible prostheses, specifically, biocompatible heart valves, are described which comprise a blend of a polyurethane (PU) and a polysiliconeurethane (PSU). Preferably, the polyurethane is a polyetherurethane (PEU). More preferably, it is a polyether... | 07/22/2003 |
| 6585767 | Antimicrobial suturing ring for heart valve A suturing ring to attach the body of an implantable heart valve to heart tissue by sutures is composed of a fabric containing an inorganic antimicrobial agent. The fabric can have a material coating the fibers of the fabric in which particles of the agen... | 07/01/2003 |
| 6579313 | Methods for implanting cells A method for implanting cells onto a prosthesis includes the steps of: (a) providing a prosthesis including a porous tube, where at least 25% of the pores on the inner surface of the tube have diameters of more than about 40 μm, at least 25% of the pores... | 06/17/2003 |
| 6551683 | Preform for making a prosthetic limb socket A preform for making a prosthetic limb socket includes an injection molded flat circular disk of rigid thermoplastics material, and the disk has a peripheral portion with an embedded reinforcing ring which was spaced as an insert within the mold cavity. T... | 04/22/2003 |
| 6541116 | Superoxide dismutase or superoxide dismutase mimic coating for an intracorporeal medical device A method of providing a therapeutic, diagnostic or lubricious hydrophilic coating on an intracorporeal medical device and the coated device produced thereby, wherein the coating is durable. In one embodiment, the coating comprises a polymerized base coat ... | 04/01/2003 |
| 6511510 | Osteoinductive ceramic materials The invention relates to an osteoinductive biomaterial, which is based on a ceramic material and which has a total porosity of 20 to 90%, wherein macropores are present having a size ranging from 0.1 to 1.5 mm, and wherein micropores are present having a ... | 01/28/2003 |
| 6511507 | Article with biocompatible coating A coating composition is provided comprising hyaluronic acid or a salt thereof and a blocked polyisocyanate in a solvent comprising water. A method is provided for preparing the coating on a substrate comprising forming a coating mixture of hyaluronic aci... | 01/28/2003 |
| 6437073 | Non-elastomeric polyurethane compositions A non-elastomeric polyurethane composition which includes a first chain extender of the general formula (I) ##STR1## wherein R1, R2, R3, R4, R5, and R6 are the same or different and selecte... | 08/20/2002 |
| 6410044 | Crosslinkable macromers A crosslinkable macromer system and related methods of preparing the system and using the system in the form of a crosslinked matrix between a tissue site and an implant article such as a tissue implant or on the porous surface of a prosthetic device. The... | 06/25/2002 |
| 6399215 | Ultrafine-grained titanium for medical implants We disclose ultrafine-grained titanium. A coarse-grained titanium billet is subjected to multiple extrusions through a preheated equal channel angular extrusion (ECAE) die, with billet rotation between subsequent extrusions. The resulting billet is cold p... | 06/04/2002 |
| 6387450 | Method for preparing a biocompatible coating A coating composition is provided comprising hyaluronic acid or a salt thereof and a blocked polyisocyanate in a solvent comprising water. A method is provided for preparing the coating on a substrate comprising forming a coating mixture of hyaluronic aci... | 05/14/2002 |
| 6368356 | Medical devices comprising hydrogel polymers having improved mechanical properties The invention provides a means of boosting the mechanical performance of shaped shaped medical devices comprising polymer hydrogels, such as stents, so that they may be more easily inserted into or removed from the body. In one aspect, the invention provi... | 04/09/2002 |
| 6316091 | Method for preparing synthetic bone substitutes with controlled porosity The invention concerns a method for preparing macro-porous synthetic ceramics designed in particular for bone substitution. The invention also concerns macro-porous synthetic ceramics comprising pores of controlled dimensions, distributed in number and in... | 11/13/2001 |
| 6290723 | Method of making a synthetic triglyceride filler material A filler material for a surgically implantable prosthesis comprised of a synthetic triglyceride having a viscosity substantially greater than that of naturally occurring triglycerides is provided. The triglyceride composition is formed of saturated alkyl ... | 09/18/2001 |
| 6281262 | Shape-memory, biodegradable and absorbable material Shape-memory biodegradable and absorbable materials which make it possible to easily treat vital tissues by suture, anastomosis, ligation, fixation, reconstitution, prosthesis, etc. without causing burn. These materials never induce halation in MRI or CT ... | 08/28/2001 |
| 6270530 | Prosthetic repair fabric A prosthetic repair fabric including a sheet of tissue infiltratable fabric and a second sheet, also preferably including tissue infiltratable fabric, which is united with the first sheet. The second sheet is fused to an adhesion resistant barrier, formin... | 08/07/2001 |
| 6267784 | Intraocular lens and haptics made of a copolymer A one piece intraocular lens and an intraocular lens include an optic portion and a haptic portion formed from a copolymer that includes an incorporated hydrophilic monomer and an incorporated alkoxyalkyl methacrylate monomer. The optic and haptic portion... | 07/31/2001 |
| 6241771 | Resorbable interbody spinal fusion devices A resorbable interbody fusion device for use in spinal fixation is disclosed. The device is composed of 25-100% bioresorbable or resorbable material. The interbody fusion device of the invention can be in any convenient form, such as a wedge, screw or cag... | 06/05/2001 |
| 6241766 | Intraocular lenses made from polymeric compositions Ophthalmic lenses, such as intraocular lenses, include cross-linked polymeric materials having a first constituent derived from a first monomeric component selected from the group consisting of acrylates, methacrylates and mixtures thereof, and a second c... | 06/05/2001 |
| 6193749 | Calcification-resistant biomaterials In general, the invention features a bioprosthetic article including a biocompatible material having at least one bound exogenous storage structure, the storage structure having a quantity of calcification inhibitors releasably bound thereto. The storage ... | 02/27/2001 |
| 6187042 | Intraocular lens coating compositions Intraocular lens coating compositions for reducing the risk of posterior capsule opacification are disclosed. The coating materials, which differ from the substrate material, consist essentially of at least two aryl acrylic hydrophobic monomers of the for... | 02/13/2001 |
| 6171343 | Ultra high molecular weight polyethylene components treated to resist shearing and frictional wear The present invention provides methods for modifying surfaces made from metal alloy and/or UHMWPE, preferably surfaces which are frictionally engaged, e.g., in an orthopaedic implant. The methods of the present invention reduce the coefficient of friction... | 01/09/2001 |
| 6132470 | Apparatus and method for protecting prosthetic joint assembly from wear The disclosure relates to a tissue and debris barrier for use in association with implanted joint replacement devices. The barrier comprises a biocompatible membrane that is impermeable to debris. The membrane defines an aperture which is positioned about... | 10/17/2000 |
| 5840240 | Method of making a silicone composite vascular graft A silicone/DACRON polyester composite vascular graft especially well suited as an arteriovenous (A-V) graft fistula for dialysis application. The graft has the ability to seal around needle puncture holes without externally applied pressure, excellent ant... | 11/24/1998 |
| 5217495 | Synthetic semiabsorbable composite yarn A semi-bioabsorbable connective tissue prosthesis, e.g., a replacement for the human anterior cruciate ligament, is provided whose stress-strain characteristics closely match those of the natural tissue.... | 06/08/1993 |
| 5158573 | Injectable polymeric bodies An injectable composition consisting of a plurality of discrete physiologically-compatible, non-biodegradable, silicone rubber bodies, said bodies having (i) a maximum outside dimension of from about 0.005 to 0.08 inch (125 to 2000μ), (ii) reversible def... | 10/27/1992 |
| 5141522 | Composite material having absorbable and non-absorbable components for use with mammalian tissue The invention is a composite material of two or more biocompatible polymers, at least one of which is polytetrafluoroethylene (PTFE) and one of which is a bioabsorbable polymer. The nonabsorbable PTFE is used in the composite as a reinforcing binder. The ... | 08/25/1992 |